8,410 research outputs found
The Future of Cloud-Based Library Systems
The limits of the now-aging integrated library system (ILS) software model are constraining the presence of the library within the new reality of the Internet and interconnected World Wide Web. Whether they are called cloud-based ILS or library services platforms, developing and future systems will move beyond shared library resources on shelves to establishing a shared technological infrastructure for supporting all that libraries do. Cloud-based systems will provide means for management of all library systems, including circulation, cataloging, acquisitions, serials, electronic resources, authentication, the public interface, and analytics for data in the system. All this will allow for greater cooperation among libraries and a strengthening of patron-driven print and digital services, thus getting the information to the user and fulfilling her information needs
The effects of peer influence on adolescent pedestrian road-crossing decisions
Objective: Adolescence is a high-risk period for pedestrian injury. It is also a time of heightened susceptibility to peer influence. The aim of this research was to examine the effects of peer influence on the pedestrian road-crossing decisions of adolescents.
Methods: Using 10 videos of road-crossing sites, 80 16- to 18-year-olds were asked to make pedestrian road-crossing decisions. Participants were assigned to one of 4 experimental conditions: negative peer (influencing unsafe decisions), positive peer (influencing cautious decisions), silent peer (who observed but did not comment), and no peer (the participant completed the task alone). Peers from the adolescent’s own friendship group were recruited to influence either an unsafe or a cautious decision.
Results: Statistically significant differences were found between peer conditions. Participants least often identified safe road-crossing
sites when accompanied by a negative peer and more frequently identified dangerous road-crossing sites when accompanied by a positive peer. Both cautious and unsafe comments from a peer influenced adolescent pedestrians’ decisions.
Conclusions: These findings showed that road-crossing decisions of adolescents were influenced by both unsafe and cautious comments from their peers. The discussion highlighted the role that peers can play in both increasing and reducing adolescent risk-taking
Autophagy dysregulation in cell culture and animals models of Spinal Muscular Atrophy
Abnormal autophagy has become a central thread linking neurodegenerative diseases, particularly of the motor neuron. One such disease is spinal muscular atrophy (SMA), a genetic neuromuscular disorder caused by mutations in the SMN1 gene resulting in low levels of Survival Motor Neuron (SMN) protein. Despite knowing the causal protein, the exact intracellular processes that are involved in the selective loss of motor neurons remains unclear. Autophagy induction can be helpful or harmful depending on the situation, and we sought to understand the state of the autophagic response in SMA. We show that cell culture and animal models demonstrate induction of autophagy accompanied by attenuated autophagic flux, resulting in the accumulation of autophagosomes and their associated cargo. Expression of the SMN-binding protein a-COP, a known modulator of autophagic flux, can ameliorate this autophagic traffic jam
Curriculum for Excellence Draft Experiences and Outcomes: Collection, analysis and reporting of data. Interim report.
An X-Ray Study of the Supernova Remnant G290.1-0.8
G290.1-0.8 (MSH 11-61A) is a supernova remnant (SNR) whose X-ray morphology
is centrally bright. However, unlike the class of X-ray composite SNRs whose
centers are dominated by nonthermal emission, presumably driven by a central
pulsar, we show that the X-ray emission from G290.1-0.8 is thermal in nature,
placing the remnant in an emerging class which includes such remnants as W44,
W28, 3C391, and others. The evolutionary sequence which leads to such X-ray
properties is not well understood. Here we investigate two scenarios for such
emission: evolution in a cloudy interstellar medium, and early-stage evolution
of a remnant into the radiative phase, including the effects of thermal
conduction. We construct models for these scenarios in an attempt to reproduce
the observed center-filled X-ray properties of G290.1-0.8, and we derive the
associated age, energy, and ambient density conditions implied by the models.
We find that for reasonable values of the explosion energy, the remnant age is
of order (1 - 2) x 10^{4} yr. This places a fairly strong constraint on any
association between G290.1-0.8 and PSR J1105-610, which would require an
anomalously large velocity for the pulsar.Comment: 7 pages, 7 figures, ApJ, accepte
Learning From NCLB: School Responses to Accountability Pressure and Student Subgroup Performance
Much has been written in the last decade about the spotlight that the No Child Left Behind Act (NCLB) shines on schoolperformance. Proponents and opponents alike are quick to discuss the law’s rigid definitions of school performance— exemplified by the classification of schools as making Adequate Yearly Progress (AYP) or not making AYP based largely on annual tests in reading and mathematics, disaggregating school performance by student subgroups, and requiring that all schools reach 100% proficiency. Yet for all its rigidity, the law has offered schools little guidance on how to make use of the performance data that the new systems provide or how to design improvement efforts. As policymakers discuss ways to change NCLB or design new federal education policies targeted at improving academic achievement, we present new research findings that can help to inform those discussions.
In this CPRE Policy Brief, we examine the extent to which the assumptions in the law manifest themselves in the actions that school leaders take. This brief asks and answers the question: How do school leaders—administrators and teachers— respond to the results of state assessment systems and the pressure of performance-based accountability? And do those responses seem to matter to achievement outcomes
Perfectionism, achievement motives, and attribution of success and failure in female soccer players
While some researchers have identified adaptive perfectionism as a key characteristic to achieving elite performance in sport, others see perfectionism as a maladaptive characteristic that undermines, rather than helps, athletic performance. Arguing that perfectionism in sport contains both adaptive and maladaptive facets, the present article presents a study of N 5 74 female soccer players investigating how two facets of perfectionism—perfectionistic strivings and negative reactions to imperfection (Stoeber, Otto, Pescheck, Becker, & Stoll, 2007)—are related to achievement motives and attributions of success and failure. Results show that striving for perfection was related to hope of success and self-serving attributions (internal attribution of success). Moreover, once overlap between the two facets of perfectionism was controlled for, striving for perfection was inversely related to fear of failure and self-depreciating attributions (internal attribution of failure). In contrast,
negative reactions to imperfection were positively related to fear of failure and self-depreciating attributions (external attribution of success) and inversely related to self-serving attributions (internal attribution of success and external attribution of failure). It is concluded that striving for perfection in sport is associated with an adaptive pattern of positive motivational orientations and self-serving attributions of success and failure, which
may help athletic performance. In contrast, negative reactions to imperfection are associated with a maladaptive
pattern of negative motivational orientations and self-depreciating attributions, which is likely to undermine athletic performance. Consequently, perfectionism in sport may be adaptive in those athletes who strive for perfection, but can control their negative reactions when performance is less than perfect
Особливості сучасних інтеграційних процесів для економіки України
Avoidance motivation has been associated with a wide range of negative psychological consequences, such as performance decrements, resource depletion, and reduced well-being, particularly in the long run. Here, we discuss the processes underlying these negative consequences. We put forward a research agenda, suggesting how knowledge of these processes can be translated into strategies that reduce the negative consequences of avoidance motivation. We propose and review initial support for three such strategies: (a) removing stressors, (b) providing structure and focus, and (c) creating opportunities to replenish and reinvigorate
Testing a model of antecedents and consequences of defensive pessimism and self-handicapping in school physical education
There has been very limited research on the use of self-worth protection strategies in the achievement context of school physical education (PE). Thus, this study aimed to examine some antecedents and consequences of defensive pessimism and self-handicapping. The sample comprised 534 (females n = 275; males n = 259) British pupils recruited from two schools who responded to established questionnaires. Results of structural equation modelling analysis indicated that self-handicapping and defensive pessimism were positively predicted by fear of failure and negatively predicted by competence valuation. In addition, defensive pessimism was negatively predicted by physical self-concept. In turn, defensive pessimism negatively predicted enjoyment in PE and intentions to participate in future optional PE programs. Self-handicapping did not predict enjoyment or intentions. Results from multi-sample structural equation modelling showed the specified model to be largely invariant across males and females. The findings indicate that although both strategies aim to protect one’s self-worth, some of their antecedents and consequences in PE may differ
A 3-dimensional fibre scaffold as an investigative tool for studying the morphogenesis of isolated plant cells
Background:
Cell culture methods allow the detailed observations of individual plant cells and their internal processes. Whereas cultured cells are more amenable to microscopy, they have had limited use when studying the complex interactions between cell populations and responses to external signals associated with tissue and whole plant development. Such interactions result in the diverse range of cell shapes observed in planta compared to the simple polygonal or ovoid shapes in vitro. Microfluidic devices can isolate the dynamics of single plant cells but have restricted use for providing a tissue-like and fibrous extracellular environment for cells to interact. A gap exists, therefore, in the understanding of spatiotemporal interactions of single plant cells interacting with their three-dimensional (3D) environment. A model system is needed to bridge this gap. For this purpose we have borrowed a tool, a 3D nano- and microfibre tissue scaffold, recently used in biomedical engineering of animal and human tissue physiology and pathophysiology in vitro.
Results:
We have developed a method of 3D cell culture for plants, which mimics the plant tissue environment, using biocompatible scaffolds similar to those used in mammalian tissue engineering. The scaffolds provide both developmental cues and structural stability to isolated callus-derived cells grown in liquid culture. The protocol is rapid, compared to the growth and preparation of whole plants for microscopy, and provides detailed subcellular information on cells interacting with their local environment. We observe cell shapes never observed for individual cultured cells. Rather than exhibiting only spheroid or ellipsoidal shapes, the cells adapt their shape to fit the local space and are capable of growing past each other, taking on growth and morphological characteristics with greater complexity than observed even in whole plants. Confocal imaging of transgenic Arabidopsis thaliana lines containing fluorescent microtubule and actin reporters enables further study of the effects of interactions and complex morphologies upon cytoskeletal organisation both in 3D and in time (4D).
Conclusions:
The 3D culture within the fibre scaffolds permits cells to grow freely within a matrix containing both large and small spaces, a technique that is expected to add to current lithographic technologies, where growth is carefully controlled and constricted. The cells, once seeded in the scaffolds, can adopt a variety of morphologies, demonstrating that they do not need to be part of a tightly packed tissue to form complex shapes. This points to a role of the immediate nano- and micro-topography in plant cell morphogenesis. This work defines a new suite of techniques for exploring cell-environment interactions
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