First-principle calculations of Dark Matter scattering off light nuclei

We study the scattering of Dark Matter particles off various light nuclei within the framework of chiral effective field theory. We focus on scalar interactions and include one- and two-nucleon scattering processes whose form and strength are dictated by chiral symmetry. The nuclear wave functions are calculated from chiral effective field theory interactions as well and we investigate the convergence pattern of the chiral expansion in the nuclear potential and the Dark Matter-nucleus currents. This allows us to provide a systematic uncertainty estimate of our calculations. We provide results for ${}^2$H, ${}^3$H, and ${}^3$He nuclei which are theoretically interesting and the latter is a potential target for experiments. We show that two-nucleon currents can be systematically included but are generally smaller than predicted by power counting and suffer from significant theoretical uncertainties even in light nuclei. We demonstrate that accurate high-order wave functions are necessary in order to incorporate two-nucleon currents. We discuss scenarios in which one-nucleon contributions are suppressed such that higher-order currents become dominant

The governance of genomic biobank research in Africa: reframing the regulatory tilt

Genomic biobank research has experienced exponential growth in recent years. It represents a real opportunity to remedy global health inequity that has seen limited investment in diseases affecting populations from low and middle income countries (LMICs). Previous research in Africa continent was limited to so-called parachute research whereby samples were taken from local populations for use in high income countries (HICs) with no local oversight or use of the sample. These exploitative practices must be guarded against, but the current regulation of genomic research in Africa adopts a risk-based precautionary approach, that at times is restrictive in nature. We argue that the regulation and oversight of genomic biobank research should guard against exploitative research, but in a manner that promotes reciprocal benefit and not restrictive research practices. To achieve this there must be a rebalancing of the regulatory tilt

ISM composition through X-ray spectroscopy of LMXBs

The diffuse interstellar medium (ISM) is an integral part of the evolution of the entire Galaxy. Metals are produced by stars and their abundances are the direct testimony of the history of stellar evolution. However, the interstellar dust composition is not well known and the total abundances are yet to be accurately determined. We probe ISM dust composition, total abundances, and abundance gradients through the study of interstellar absorption features in the high-resolution X-ray spectra of Galactic low-mass X-ray binaries (LMXBs). We use high-quality grating spectra of nine LMXBs taken with XMM-Newton. We measure the column densities of O, Ne, Mg, and Fe with an empirical model and estimate the Galactic abundance gradients. The column densities of the neutral gas species are in agreement with those found in the literature. Solids are a significant reservoir of metals like oxygen and iron. Respectively, 15-25 % and 65-90 % of the total amount of O I and Fe I is found in dust. The dust amount and mixture seem to be consistent along all the lines-of-sight (LOS). Our estimates of abundance gradients and predictions of local interstellar abundances are in agreement with those measured at longer wavelengths. Our work shows that X-ray spectroscopy is a very powerful method to probe the ISM. For instance, on a large scale the ISM appears to be chemically homogeneous showing similar gas ionization ratios and dust mixtures. The agreement between the abundances of the ISM and the stellar objects suggests that the local Galaxy is also chemically homogeneous.Comment: 13 pages, 10 figures, 5 tables, accepted to A&

Remote control of a streak camera for real time bunch size measurement in LEP

A double sweep streak camera, built by industry according to CERN specifications, has been used for a number of years to provide real time three-dimensional measurements of bunches in LEP, by means of a dedicated synchrotron light source. Originally requiring local manipulation in an underground lab close to the LEP tunnel, the camera can now be fully operated via the control system network. Control functions, such as the adjustment of lens and mirror positions, the selection of camera weep speeds, and the setting of 12 ps resolution trigger timing, are handled by various networked VME systems, as is real time image processing. Bunch dimension averages are transferred every few seconds via the control system to the LEP measurement database, and a dedicated high bandwidth video transmission allows the streak camera images and processed results to be viewed in real time (at 25 Hz) in the LEP control room. Feedback control loops for light intensity, trigger timing and image tracking allow the setup to provide useful bunch images and logged measurements over extended periods, without human intervention. An X-Window based control application (GUI) will allow LEP machine operators to select different bunches for display and measurement. The same application allows the specialists to control all parameters of the system

Laparoscopic Versus Open Cholecystectomy: A Prospective Matched-Cohort Study

To compare the results of laparoscopic cholecystectomy (LC) and open cholecystectomy (OC) for symptomatic cholelithiasis in elective surgery we performed a prospective matched-cohort study. Hundred consecutive patients who underwent LC in the period Sept. 1990-June 1992, and 100 patients who were age and sex matched and underwent an elective OC in the foregoing two years (1989-1990) were studied. The median operation time for LC (75, 40-180 min) was significantly longer than for OC (55, 20-155 min; p < 0.001). Postoperative hospitalization was significantly shorter after LC (3, 1-16 days), compared with OC (7, 4-22 days; p<0.001). Conversion of LC to OC occurred in 12 (12%) patients initially scheduled to undergo LC. Complications occurred in 5 patients (5%) after LC and in 5 patients (5%) after OC. The calculated expenses (operation and postoperative hospitalization, 3rd class) were approximately fl. 3740,- for LC (excl. investments for pieces of apparatus) and fl. 6725,- for OC. This study demonstrates that LC can be performed safely with the number of complications comparable to those for OC. Bile duct injury is a serious potential threat. The main advantages ofLC are the minimal trauma, with more rapid recovery. Insurers seem to benefit from reduced postoperative disability and earlier discharge

Quantum integrability of quadratic Killing tensors

Quantum integrability of classical integrable systems given by quadratic Killing tensors on curved configuration spaces is investigated. It is proven that, using a "minimal" quantization scheme, quantum integrability is insured for a large class of classic examples.Comment: LaTeX 2e, no figure, 35 p., references added, minor modifications. To appear in the J. Math. Phy

Unraveling models of CP violation through electric dipole moments of light nuclei

We show that the proposed measurements of the electric dipole moments of light nuclei in storage rings would put strong constraints on models of flavor-diagonal CP violation. Our analysis is exemplified by a comparison of the Standard Model including the QCD theta term, the minimal left-right symmetric model, a specific version of the so-called aligned two-Higgs doublet model, and briefly the minimal supersymmetric extension of the Standard Model. By using effective field theory techniques we demonstrate to what extend measurements of the electric dipole moments of the nucleons, the deuteron, and helion could discriminate between these scenarios. We discuss how measurements of electric dipole moments of other systems relate to the light-nuclear measurements.Comment: Published versio

Deuteron Magnetic Quadrupole Moment From Chiral Effective Field Theory

We calculate the magnetic quadrupole moment (MQM) of the deuteron at leading order in the systematic expansion provided by chiral effective field theory. We take into account parity and time-reversal violation which, at the quark-gluon level, results from the QCD vacuum angle and dimension-six operators that originate from physics beyond the Standard Model. We show that the deuteron MQM can be expressed in terms of five low-energy constants that appear in the parity- and time-reversal-violating nuclear potential and electromagnetic current, four of which also contribute to the electric dipole moments of light nuclei. We conclude that the deuteron MQM has an enhanced sensitivity to the QCD vacuum angle and that its measurement would be complementary to the proposed measurements of light-nuclear EDMs