302 research outputs found
Angular correlations of galaxy distribution
We study the angular correlations of various galaxy catalogs (CfA1, SSRS1,
Perseus-Pisces, APM Bright Galaxies and Zwicky). We find that the angular
correlation exponent is rather than as
usually found by the standard correlation function . We
identify the problem in the artificial decay of . Moreover we
find that no characteristic angular scale is present in any of the analyzed
catalogs. Finally we show that all the available data are consistent with each
other and the angular distribution of galaxies is quite naturally compatible
with a fractal structure with .Comment: 16 pages, latex, 3 postscript figures. Accepted for publication in
Astrophysical Journal Letters. This paper is also available at
http://www.phys.uniroma1.it/DOCS/PIL/pil.htm
Eindverslag aaltjeswijzer : geprikkeld door Aaltjes
In dit demonstratie- en kennisoverdrachtsproject is kennis rondom aaltjes en aaltjesbeheersing verzameld en vertaald naar zoveel mogelijk uniforme boodschappen naar akkerbouwers en intermediairs. Er zijn diverse brochures, leaflets en aaltjesschema’s gemaakt en breed onder de doelgroep verspreid. Daarnaast zijn er veel kennisbijeenkomsten, bijscholingen voor intermediairs (train de trainerscursus) en gruwelroutes uitgevoerd. Er zijn circa 3400 akkerbouwers bereikt via deze bijeenkomsten en circa 175 intermediairs. Via schriftelijke communicatie en mailingen van het PA zijn circa 20.000 akkerbouwers geïnformeerd over kennis, producten en adviezen vanuit dit project. De algemene tendens in de evaluaties en feedback was dat de activiteiten en producten goed aansloten bij de doelgroep
Orofacial abnormalities in mucopolysaccharidosis and mucolipidosis type II and III:A systematic review
Mucopolysaccharidoses (MPSs) and mucolipidosis II and III (ML II and III) often manifest with orofacial (progressive) abnormalities, which may have a major impact on quality of life. However, because these patients have multiple somatic health issues, orofacial problems are easily overlooked in clinical practice and available literature on this topic solely consists of case reports, small case series, and small cohort studies. The aim of this systematic review was to gain more insight in the nature and extent of orofacial abnormalities in MPS, ML II, and III. A systematic review of all previously published articles addressing orofacial abnormalities in MPS, ML II, and III was performed. Both clinical studies and case reports were included. Outcome was the described orofacial abnormalities, subdivided into abnormalities of the face, maxilla, mandible, soft tissues, teeth, and occlusion. The search resulted in 57 articles, describing orofacial features in 340 patients. Orofacial abnormalities were present in all subtypes of MPS, ML II, and III, and consisted of thickened lips, a hypoplastic midface, a high‐arched palate, hypoplastic condyles, coronoid hyperplasia, macroglossia, gingival hyperplasia, thick dental follicles, dentigerous cysts, misshapen teeth, enamel defects, and open bite. Orofacial abnormalities are present in all subtypes of MPS, ML II, and III. As orofacial abnormalities may cause complaints, evaluation of orofacial health should be part of routine clinical care
The Force-Velocity Relation for Growing Biopolymers
The process of force generation by the growth of biopolymers is simulated via
a Langevin-dynamics approach. The interaction forces are taken to have simple
forms that favor the growth of straight fibers from solution. The
force-velocity relation is obtained from the simulations for two versions of
the monomer-monomer force field. It is found that the growth rate drops off
more rapidly with applied force than expected from the simplest theories based
on thermal motion of the obstacle. The discrepancies amount to a factor of
three or more when the applied force exceeds 2.5kT/a, where a is the step size
for the polymer growth. These results are explained on the basis of restricted
diffusion of monomers near the fiber tip. It is also found that the mobility of
the obstacle has little effect on the growth rate, over a broad range.Comment: Latex source, 9 postscript figures, uses psfig.st
Modeling oscillatory Microtubule--Polymerization
Polymerization of microtubules is ubiquitous in biological cells and under
certain conditions it becomes oscillatory in time. Here simple reaction models
are analyzed that capture such oscillations as well as the length distribution
of microtubules. We assume reaction conditions that are stationary over many
oscillation periods, and it is a Hopf bifurcation that leads to a persistent
oscillatory microtubule polymerization in these models. Analytical expressions
are derived for the threshold of the bifurcation and the oscillation frequency
in terms of reaction rates as well as typical trends of their parameter
dependence are presented. Both, a catastrophe rate that depends on the density
of {\it guanosine triphosphate} (GTP) liganded tubulin dimers and a delay
reaction, such as the depolymerization of shrinking microtubules or the decay
of oligomers, support oscillations. For a tubulin dimer concentration below the
threshold oscillatory microtubule polymerization occurs transiently on the
route to a stationary state, as shown by numerical solutions of the model
equations. Close to threshold a so--called amplitude equation is derived and it
is shown that the bifurcation to microtubule oscillations is supercritical.Comment: 21 pages and 12 figure
Theory on quench-induced pattern formation: Application to the isotropic to smectic-A phase transitions
During catastrophic processes of environmental variations of a thermodynamic
system, such as rapid temperature decreasing, many novel and complex patterns
often form.
To understand such phenomena, a general mechanism is proposed based on the
competition between heat transfer and conversion of heat to other energy forms.
We apply it to the smectic-A filament growth process during quench-induced
isotropic to smectic-A phase transition. Analytical forms for the buckling
patterns are derived and we find good agreement with experimental observation
[Phys. Rev. {\bf E55} (1997) 1655]. The present work strongly indicates that
rapid cooling will lead to structural transitions in the smectic-A filament at
the molecular level to optimize heat conversion. The force associated with this
pattern formation process is estimated to be in the order of
piconewton.Comment: 9 pages in RevTex form, with 3 postscript figures. Accepted by PR
STUDIES ON THE PRESENCE OF VASOPRESSIN, OXYTOCIN AND VASOTOCIN IN THE PINEAL GLAND, SUBCOMMISSURAL ORGAN AND FETAL PITUITARY GLAND: FAILURE TO DEMONSTRATE VASOTOCIN IN MAMMALS
Energy Transduction of Isothermal Ratchets: Generic Aspects and Specific Examples Close to and Far from Equilibrium
We study the energetics of isothermal ratchets which are driven by a chemical
reaction between two states and operate in contact with a single heat bath of
constant temperature. We discuss generic aspects of energy transduction such as
Onsager relations in the linear response regime as well as the efficiency and
dissipation close to and far from equilibrium. In the linear response regime
where the system operates reversibly the efficiency is in general nonzero.
Studying the properties for specific examples of energy landscapes and
transitions, we observe in the linear response regime that the efficiency can
have a maximum as a function of temperature. Far from equilibrium in the fully
irreversible regime, we find a maximum of the efficiency with values larger
than in the linear regime for an optimal choice of the chemical driving force.
We show that corresponding efficiencies can be of the order of 50%. A simple
analytic argument allows us to estimate the efficiency in this irreversible
regime for small external forces.Comment: 16 pages, 10 figure
Statistical mechanics of semiflexible ribbon polymers
The statistical mechanics of a ribbon polymer made up of two semiflexible
chains is studied using both analytical techniques and simulation. The system
is found to have a crossover transition at some finite temperature, from a type
of short range order to a fundamentally different sort of short range order. In
the high temperature regime, the 2-point correlation functions of the object
are identical to worm-like chains, while in the low temperature regime they are
different due to a twist structure. The crossover happens when the persistence
length of individual strands becomes comparable to the thickness of the ribbon.
In the low temperature regime, the ribbon is observed to have a novel
``kink-rod'' structure with a mutual exclusion of twist and bend in contrast to
smooth worm-like chain behaviour. This is due to its anisotropic rigidity and
corresponds to an {\it infinitely} strong twist-bend coupling. The
double-stranded polymer is also studied in a confined geometry. It is shown
that when the polymer is restricted in a particular direction to a size less
than the bare persistence length of the individual strands, it develops zigzag
conformations which are indicated by an oscillatory tangent-tangent correlation
function in the direction of confinement. Increasing the separation of the
confining plates leads to a crossover to the free behaviour, which takes place
at separations close to the bare persistence length. These results are expected
to be relevant for experiments which involve complexation of two or more stiff
or semiflexible polymers.Comment: 20 pages, 11 figures. PRE (in press
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