Critical behaviors of sheared frictionless granular materials near jamming transition

Critical behaviors of sheared dense and frictionless granular materials in the vicinity of the jamming transition are numerically investigated. From the extensive molecular dynamics simulation, we verify the validity of the scaling theory near the jamming transition proposed by Otsuki and Hayakawa (Prog. Theor. Phys., 121, 647 (2009)). We also clarify the critical behaviors of the shear viscosity and the pair correlation function based on both a phenomenology and the simulation.Comment: 13pages, 26 figure

Reverse-selective diffusion in nanocomposite membranes

The permeability of certain polymer membranes with impenetrable nanoinclusions increases with the particle volume fraction (Merkel et al., Science, 296, 2002). This intriguing observation contradicts even qualitative expectations based on Maxwell's classical theory of conduction/diffusion in composites with homogeneous phases. This letter presents a simple theoretical interpretation based on classical models of diffusion and polymer physics. An essential feature of the theory is a polymer-segment depletion layer at the inclusion-polymer interface. The accompanying increase in free volume leads to a significant increase in the local penetrant diffusivity, which, in turn, increases the bulk permeability while exhibiting reverse selectivity. This model captures the observed dependence of the bulk permeability on the inclusion size and volume fraction, providing a straightforward connection between membrane microstructure and performance

Remote sensing applications in forestry. The development of an earth resources information system using aerial photographs and digital computers photographs and digital computers

Remote aerial sensing and automatic mapping for forest resources information syste

MR400: Assessing Compliance with BMPs on Harvested Sites in Maine: Final Report

The research was designed to help answer three questions: (1) What are the documented types of impacts on water quality from forestry activities in Maine? (2) Do timber harvesters use the best management practices recommended by the state to control water pollution? (3) Are these practices effective when they are used?https://digitalcommons.library.umaine.edu/aes_miscreports/1025/thumbnail.jp

Instabilities in Zakharov Equations for Laser Propagation in a Plasma

F.Linares, G.Ponce, J-C.Saut have proved that a non-fully dispersive Zakharov system arising in the study of Laser-plasma interaction, is locally well posed in the whole space, for fields vanishing at infinity. Here we show that in the periodic case, seen as a model for fields non-vanishing at infinity, the system develops strong instabilities of Hadamard's type, implying that the Cauchy problem is strongly ill-posed

Clinical Uses of Melatonin in Pediatrics

This study analyzes the results of clinical trials of treatments with melatonin conducted in children, mostly focused on sleep disorders of different origin. Melatonin is beneficial not only in the treatment of dyssomnias, especially delayed sleep phase syndrome, but also on sleep disorders present in children with attention-deficit hyperactivity, autism spectrum disorders, and, in general, in all sleep disturbances associated with mental, neurologic, or other medical disorders. Sedative properties of melatonin have been used in diagnostic situations requiring sedation or as a premedicant in children undergoing anesthetic procedures. Epilepsy and febrile seizures are also susceptible to treatment with melatonin, alone or associated with conventional antiepileptic drugs. Melatonin has been also used to prevent the progression in some cases of adolescent idiopathic scoliosis. In newborns, and particularly those delivered preterm, melatonin has been used to reduce oxidative stress associated with sepsis, asphyxia, respiratory distress, or surgical stress. Finally, the administration of melatonin, melatonin analogues, or melatonin precursors to the infants through the breast-feeding, or by milk formula adapted for day and night, improves their nocturnal sleep. Side effects of melatonin treatments in children have not been reported. Although the above-described results are promising, specific studies to resolve the problem of dosage, formulations, and length of treatment are necessary

Involvement of N-6 adenine-specific DNA methyltransferase 1 (N6AMT1) in arsenic biomethylation and its role in arsenic-induced toxicity.

BackgroundIn humans, inorganic arsenic (iAs) is metabolized to methylated arsenical species in a multistep process mainly mediated by arsenic (+3 oxidation state) methyltransferase (AS3MT). Among these metabolites is monomethylarsonous acid (MMAIII), the most toxic arsenic species. A recent study in As3mt-knockout mice suggests that unidentified methyltransferases could be involved in alternative iAs methylation pathways. We found that yeast deletion mutants lacking MTQ2 were highly resistant to iAs exposure. The human ortholog of the yeast MTQ2 is N-6 adenine-specific DNA methyltransferase 1 (N6AMT1), encoding a putative methyltransferase.ObjectiveWe investigated the potential role of N6AMT1 in arsenic-induced toxicity.MethodsWe measured and compared the cytotoxicity induced by arsenicals and their metabolic profiles using inductively coupled plasma-mass spectrometry in UROtsa human urothelial cells with enhanced N6AMT1 expression and UROtsa vector control cells treated with different concentrations of either iAsIII or MMAIII.ResultsN6AMT1 was able to convert MMAIII to the less toxic dimethylarsonic acid (DMA) when overexpressed in UROtsa cells. The enhanced expression of N6AMT1 in UROtsa cells decreased cytotoxicity of both iAsIII and MMAIII. Moreover, N6AMT1 is expressed in many human tissues at variable levels, although at levels lower than those of AS3MT, supporting a potential participation in arsenic metabolism in vivo.ConclusionsConsidering that MMAIII is the most toxic arsenical, our data suggest that N6AMT1 has a significant role in determining susceptibility to arsenic toxicity and carcinogenicity because of its specific activity in methylating MMAIII to DMA and other unknown mechanisms

Direct Numerical Simulations of Electrophoresis of Charged Colloids

We propose a numerical method to simulate electrohydrodynamic phenomena in charged colloidal dispersions. This method enables us to compute the time evolutions of colloidal particles, ions, and host fluids simultaneously by solving Newton, advection-diffusion, and Navier--Stokes equations so that the electrohydrodynamic couplings can be fully taken into account. The electrophoretic mobilities of charged spherical particles are calculated in several situations. The comparisons with approximation theories show quantitative agreements for dilute dispersions without any empirical parameters, however, our simulation predicts notable deviations in the case of dense dispersions.Comment: 4pages, 3figures, to appear in Phys. Rev. Let

High-Dispersion Optical Spectra of Nearby Stars Younger Than The Sun

We present high-dispersion (R~16,000) optical (3900-8700 A) spectra of 390 stars obtained with the Palomar 60 inch telescope. The majority of stars observed are part of the Spitzer Legacy Science Program "The Formation and Evolution of Planetary Systems." Through detailed analysis we determine stellar properties for this sample, including radial and rotational velocities, Li I 6708 and Ha equivalent widths, the chromospheric activity index R'_HK, and temperature- and gravity-sensitive line ratios. Several spectroscopic binaries are also identified. From our tabulations, we illustrate basic age- and rotation-related correlations among measured indices. One novel result is that Ca II chromospheric emission appears to saturate at vsini values above ~30 km/s, similar to the well established saturation of X-rays that originate in the spatially separate coronal regions.Comment: 1 electronic table; published in the Astronomical Journa