Antibacterial activity the βCD-AT-AuNPs, βCD-AT and AT.

<p>Antibacterial activity the βCD-AT-AuNPs, βCD-AT and AT.</p

ROESY spectra of the βCD-AT complex and proposed inclusion geometries.

<p>Cross peaks between: (A) the H-3, H-5 and H-6 protons of βCD with the H’-2’/3’/5’/6’ protons of the aromatic ring of AT, (B) OH-2 and OH-3 groups of βCD with the H’-2’/3’/5’/6’ protons of the aromatic ring of AT, (C) OH-2 and OH-3 groups of βCD with NH₂’-2 and H'-5 protons of the thiazole group of AT.(D) Proposed inclusion geometries of the βCD-AT complex.</p

Chemical shifts of the IC and free species.

<p>Chemical shifts of the IC and free species.</p

SEM micrographs.

<p>Shown are (A) pure AT, (B) pure βCD, (C, D), βCD-AT crystals, and (E) AuNPs deposited on the βCD-AT crystals.</p

Powder x-ray diffraction (PXRD) intensities.

<p>PXRD diffractograms of (A) βCD, (B) AT,(C) the βCD-AT complex, and (D) the physical βCD/AT mixture.</p

AuNPs absorbance spectrum and TEM data.

<p>(A) Absorbance spectrum of AuNPs deposited on IC microcrystals using sputtering for 30 s. (B)TEM micrograph (left) of AuNPs covered with the IC (20000X magnification) and the respective histogram (right).</p

βCD-AT-AuNPs ternary system.

<p>Schematic representation of AuNPs deposited via sputtering on crystalline powder of βCD-AT forming the ternary system.</p

Antibacterial activity the βCD-AT-AuNPs, βCD-AT and AT.

<p>Antibacterial activity the βCD-AT-AuNPs, βCD-AT and AT.</p

Structural representation of (A) βCD and (B) AT.

<p>Structural representation of (A) βCD and (B) AT.</p

Effective permeability measurements.

<p>Shown are the effective permeability for the AT drug, βCD-AT complex, and βCD-AT-AuNPs system, as well as the corresponding positive (+) and negative (-) controls.</p