Remote Predictive Mapping 5. Using a Lidar Derived DEM to Test the Influence of Variable Overburden Thickness and Bedrock on Drainage and Basin Morphology

A 4–m lidar digital elevation model (DEM) provides sufficient resolution to examine the impact of variable till cover on the incision history of multiple small (5 km2) catchments in eastern Canada.  The study site was selected because it has homogeneous bedrock geology that dips parallel to the land surface, is tectonically stable, has undergone common base level changes, and has a common ice history, with variable overburden thickness, from thin cover in the west to thick cover in the east. Basin morphometrics were compared for similar-size basins that have variable till cover thicknesses. Basins with thicker till cover are wider and show differences in hypsometries compared to those where till cover is thin. Two basins representing end members of till thickness were measured for stream discharge and water chemistry. Thick till  (> 1 m) on the eastern half of North Mountain retards infiltration sufficiently to promote overland flow and accelerate incision relative to areas with thinner till.  Till thickness and continuity therefore are expected to impede the achievement of steadiness and may also delay stream power law relationships in larger catchments until till cover has been effectively eroded.SOMMAIREUn modèle altimétrique numérique (MAN) par lidar 4 m offre une résolution suffisante pour étudier l'impact des divers dépôts de till sur l'histoire de l'érosion linéaire de multiples petits (5 km2) bassins versants dans l'Est du Canada.  Le site d'étude a été choisi parce que sa géologie est homogène et que son pendage est parallèle à la surface du sol, qu’il est tectoniquement stable, qu’il a subi des changements similaires du niveau de base d’érosion, de même qu’ une histoire glaciaire similaire, avec une épaisseur de mort-terrain variable, d’une couverture mince à l'ouest jusqu'à une couverture épaisse à l'est. La morphométrie du bassin a été comparée à celle de bassins de taille semblable aux épaisseurs de till variables.  Les bassins aux couvertures de till plus épaisses sont plus larges et montrent des différences hypsométriques comparé  à ceux aux couvertures minces.  Deux bassins représentant les termes extrêmes de l'épaisseur du till ont été mesurées quant au débit du courant et à la chimie de l'eau.  Les till épais (>1 m) sur la moitié est du mont Nord retardent l'infiltration, ce qui favorise l'écoulement en surface et accélèrent l’érosion linéaire par rapport aux zones couvertes de couches de till plus minces.  On s’attend donc à ce que l'épaisseur de la couche de till et sa continuité agissent comme une entrave à la stabilité et puissent aussi retarder les effets de la loi de puissance de l’écoulement dans les grands bassins récepteurs jusqu'à ce que la couverture de till a été effectivement érodée

Time--Splitting Schemes and Measure Source Terms for a Quasilinear Relaxing System

Several singular limits are investigated in the context of a $2 \times 2$ system arising for instance in the modeling of chromatographic processes. In particular, we focus on the case where the relaxation term and a $L^2$ projection operator are concentrated on a discrete lattice by means of Dirac measures. This formulation allows to study more easily some time-splitting numerical schemes

Using Fill Terraces to Understand Incision Rates and Evolution of the Colorado River in Eastern Grand Canyon, Arizona

The incision and aggradation of the Colorado River in eastern Grand Canyon through middle to late Quaternary time can be traced in detail using well-exposed fill terraces dated by a combination of optically stimulated luminescence, uranium series, and cosmogenic nuclide dating. This fluvial history provides the best bedrock incision rate for this important landscape and highlights the complications and advantages of fill terrace records for understanding river long-profile evolution and incision. The use of fill terraces, as distinct from strath terraces, for calculating incision rates is complicated by the cyclic alluviation and incision they record. In the example of the Grand Canyon this has led to various rates being reported by different workers and rates that tend to be overestimates in shorter records. We illustrate that a meaningful long-term bedrock incision rate of 140 m/m.y. can be extracted from the Grand Canyon record by linking episodes when the Colorado River is floored on bedrock. Variable incision rates reported in the greater region may be, to some degree, due to inconsistent calculations. Our data also highlight that the Colorado River has been a mixed alluvial-bedrock river through both time and space and has been a bedrock river for less than half of its Pleistocene history. This strong temporal variation, combined with the varying bedrock the river encounters on its path, heightens the challenge of understanding the tectonic, climatic, and drainage integration controls on the form and evolution of the Colorado River’s long profile

Cultured skin microbiota attracts malaria mosquitoes

This is an Open Access article distributed under the terms of the Creative Commons Attribution Licens

Interaction between superconducting vortices and Bloch wall in ferrite garnet film

Interaction between a Bloch wall in a ferrite-garnet film and a vortex in a superconductor is analyzed in the London approximation. Equilibrium distribution of vortices formed around the Bloch wall is calculated. The results agree quantitatively with magneto-optical experiment where an in-plane magnetized ferrite-garnet film placed on top of NbSe2 superconductor allows observation of individual vortices. In particular, our model can reproduce a counter-intuitive attraction observed between vortices and a Bloch wall having the opposite polarity. It is explained by magnetic charges appearing due to discontinuity of the in-plane magnetization across the wall.Comment: 4 pages, 5 figure

DC-STAMP knock-down deregulates cytokine production and T-cell stimulatory capacity of LPS-matured dendritic cells

Contains fulltext : 96778.pdf (publisher's version ) (Open Access)ABSTRACT: BACKGROUND: Dendritic cells (DCs) are the highly specialized antigen presenting cells of the immune system that play a key role in regulating immune responses. DCs can efficiently initiate immune responses or induce tolerance. Due to this dual function, DCs are studied in the context of immunotherapy for both cancer and autoimmune diseases. Characterization of DC-specific genes, leading to better understanding of DC immunobiology, will help to guide their use in clinical settings. We previously identified DC-STAMP, a multi-membrane spanning protein preferentially expressed by DCs. DC-STAMP resides in the endoplasmic reticulum (ER) of immature DCs and translocates towards the Golgi compartment upon maturation. In this study we knocked down DC-STAMP in mouse bone marrow-derived DCs (mBMDCs) to determine its function. RESULTS: We demonstrate that DC-STAMP knock-down mBMDCs secrete less IL-6, IL-12, TNF-alpha and IL-10 while IL-1 production is enhanced. Moreover, LPS-matured DC-STAMP knock-down mBMDCs show impaired T cell activation potential and induction of Th1 responses in an alloreaction. CONCLUSIONS: We show that DC-STAMP plays an important role in cytokine production by mBMDCs following LPS exposure. Our results reveal a novel function of DC-STAMP in regulating DC-initiated immune responses

Particle approximation of the one dimensional Keller-Segel equation, stability and rigidity of the blow-up

We investigate a particle system which is a discrete and deterministic approximation of the one-dimensional Keller-Segel equation with a logarithmic potential. The particle system is derived from the gradient flow of the homogeneous free energy written in Lagrangian coordinates. We focus on the description of the blow-up of the particle system, namely: the number of particles involved in the first aggregate, and the limiting profile of the rescaled system. We exhibit basins of stability for which the number of particles is critical, and we prove a weak rigidity result concerning the rescaled dynamics. This work is complemented with a detailed analysis of the case where only three particles interact