A Social Network Analysis and Comparison of Six Dark Web Forums

With increasing monitoring and regulation by platforms, communities with criminal interests are moving to the dark web, which hosts content ranging from whistle-blowing and privacy, to drugs, terrorism, and hacking. Using post discussion data from six dark web forums we construct six interaction graphs and use social network analysis tools to study these underground communities. We observe the structure of each network to highlight structural patterns and identify nodes of importance through network centrality analysis. Our findings suggest that in the majority of the forums some members are highly connected and form hubs, while most members have a lower number of connections. When examining the posting activities of central nodes we found that most of the central nodes post in sub-forums with broader topics, such as general discussions and tutorials. These members play different roles in the different forums, and within each forum we identified diverse user profiles.EPSRC Doctoral Training Studentship (Jack Hughes

Assessment of variability in proximate/anti-nutritive composition of cocoyam within Nigeria and Uganda

The availability of cheaper food energy sources which compares favourably with other high priced cereals is of importance and should be encouraged. This study investigated the proximate/anti-nutritive contents of cocoyam collected from Southern Nigeria and Eastern Uganda to investigate if agronomic or climatic factors play a role in its composition. The proximate/mineral composition of cormels (crude protein:0.35 – 6.9%; carbohydrates: 60.01 – 83.66%; Fe: 3.65 - 16.80 mg/100g, Zn: 1.39 – 2.45 mg/100g) show that cocoyam can conveniently replace yams and potatoes in diets due to its similar carbohydrate contents though lower in crude fibre content (0.99 – 2.80%). Cocoyam samples contained high anti-nutrients (Cyanides 0.94 – 2.16 %; Oxalates 8.45 – 181.4 mg/Kg) which may limit its utilization. An analysis of variance indicate cocoyam differ significantly (p<0.05) in proximate/anti-nutritive contents across the two locations with a higher content of crude fibre, crude protein and carbohydrates observed in samples collected in southern Nigeria

Free proline, soluble sugars and soluble proteins concentration as affected by salt stress in two sugarcane (Saccharum sp.) cultivars differing in their salt tolerance

Salt stress is one of the environmental stresses which affect negatively the agricultural production of the world. In this study, the effects of salt stress on free proline, soluble sugars and soluble proteins accumulation were investigated in two sugarcane (Saccharum sp.) cultivars: CP66-346 (salt- tolerant) and CP65-357 (salt-sensitive). Young plants of these cultivars were exposed, in a hydroponic system, to four concentrations of NaCl (0, 17, 34 and 68 mM). These concentrations correspond to an electric conductivity of 1; 2.83; 4.26 and 6.63 mS/cm, respectively. Free proline, soluble sugars and proteins accumulation were quantified after 2 weeks of stress. Proline and soluble sugars concentrations increased significantly in leaves and roots under salinity. Furthermore, NaCl caused an increase in soluble proteins concentration in leaves and roots of the tolerant cultivar CP66-346 and a decrease in leaves and roots of the sensitive CP65-357. Salttolerant CP66-346 plants accumulated more soluble sugars in leaves than CP65-357, while both cultivars accumulated similar quantities of proline in leaves. These results provided evidence that soluble sugars could contribute mainly to counteract the negative water potential of the outside medium and that protein synthesis stimulation was implicated in sugarcane salt tolerance. Proline appeared as a symptom in salt-stressed sugarcane plants rather than as an indicator of tolerance.Keywords: Sugarcane, Saccharum sp., proline, soluble sugars, soluble proteins, salt-toleranc

Cross-Product Extensions of the Gene Ontology

The Gene Ontology is being normalized and extended to include computable logical definitions. These definitions are partitioned into mutually exclusive cross-product sets, many of which reference other OBO Foundry ontologies. The results can be used to reason over the ontology, and to make cross-ontology queries

Extraterrestrial Helium Trapped in Fullerenes in the Sudbury Impact Structure

Fullerenes (C60 and C70) in the Sudbury impact structure contain trapped helium with a He-3/He-4 ratio of 5.5 x 10(exp -4) to 5.9 x 10(exp -4). The He-3/He-4 ratio exceeds the accepted solar wind value by 20 to 30 percent and is higher by an order of magnitude than the maximum reported mantle value. Terrestrial nuclear reactions or cosmic-ray bombardment are not sufficient to generate such a high ratio. The He-3/He-4 ratios in the Sudbury fullerenes are similar to those found in meteorites and in some interplanetary dust particles. The implication is that the helium within the C60 molecules at Sudbury is of extraterrestrial origin

Effects of Perinatal Oxycodone Exposure on the Cardiovascular Response to Acute Stress in Male Rats at Weaning and in Young Adulthood

Oxycodone (OXY) is one of the most commonly abused opiates during pregnancy. Perinatal opiate exposure (POE) is associated with neurobehavioral and hormone changes. Little is known about the effects of perinatal OXY on the cardiovascular (CV) responses to stress. Objectives: to determine the effects of POE on: (1) CV responses to acute stress and ability to discriminate using a classical conditioning paradigm; (2) changes in CV response to the paradigm and retention of the ability to discriminate from postnatal day (PD) 40 to young adulthood. Methods: Pregnant rats were given i.v. OXY or vehicle (CON) daily. OXY and CON males were fitted with BP telemetry units. Offspring were classically conditioned by following a pulsed tone (CS+) with tail shock. A steady tone (CS-) was not followed by shock. BP and HR were recorded during resting periods and conditioning. Changes in BP, HR from composite analysis were compared. The paradigm was repeated on PD 75. Results: At PD 40, OXY rats had a lower baseline mean BP (OXY: 114.8 ± 1.0 vs. CON: 118.3 ± 1.0 mm Hg; mean ± SEM) but larger amplitude of the conditional BP increase during the stress response (OXY: +3.9 ± 0.4 vs. CON: +1.7 ± 0.4 mm Hg). Both OXY and CON rats were able to discriminate between CS+ and CS-. At PD 75, the effects of OXY on the increased amplitude of the conditional BP had dissipated (CON: +3.4 ± 2.3 vs. OXY: +4.5 ± 1.4 mm Hg). BP responses to the stress and non-stress stimuli did not differ in the OXY group, suggesting that OXY may have decreased the ability of the offspring to discriminate (OXY: CS+: 147.1 ± 1.6, CS-: 145.9 ± 1.6 mm Hg vs. CON: CS+: 155.4 ± 2.7, CS-: 147.8 ± 2.7 mm Hg). Conclusion: POE is associated with subtle alterations in stress CV responses in weanling rats which dissipate when the conditioning is repeated at an early adult age. Although POE effect on the ability to discriminate at weanling age could not be detected, POE may impair retention of this ability in adulthood

Complete homochirality induced by the nonlinear autocatalysis and recycling

A nonlinear autocatalysis of a chiral substance is shown to achieve homochirality in a closed system, if the back-reaction is included. Asymmetry in the concentration of two enantiomers or the enantiometric excess increases due to the nonlinear autocatalysis. Furthermore, when the back-reaction is taken into account, the reactant supplied by the decomposition of the enantiomers is recycled to produce more and more the dominant one, and eventually the homochirality is established.Comment: 4 pages, 2 figure

AMINO ACID ANALYSES OF THE ANTARCTIC CM2 METEORITES ALH 83100 AND LEW 90500 USING LIQUID CHROMATOGRAPHY-TIME OF FLIGHT-MASS SPECTROMETRY

The investigation of organic compounds in primitive carbonaceous meteorites provides a record of the chemical processes that occurred in the early solar system. In particular, amino acids have been shown to be potential indicators in tracing the nature of carbonaceous chondrite parent bodies [ 13. The delivery of amino acids by carbonaceous chondrites to the early Earth could have been any important source of the Earth's prebiotic organic inventory [2]. Over 80 different amino acids have been detected in the Murchison CM2 meteorite, most of them completely non-existent in the terrestrial biosphere [3]. We have optimized a new liquid chromatography-time-of-flight-mass spectrometry (LC-ToF-MS) technique coupled with OPAMAC derivatization in order to detect amino acids in meteorite extracts by UV fluorescence and exact mass simultaneously. The detection limit of the LC-ToF-MS instrument for amino acids is at least 3 orders of magnitude lower than traditional GC-MS techniques. Here we report on the first analyses of amino acids and their enantiomeric abundances in the CM2 carbonaceous meteorites ALH 83100, LEW 90500, and Murchison using this new LC-ToF-MS instrument configuration. Amino acid analyses of any kind for the CM meteorite ALH 83100 have not previously been reported

Homochiral growth through enantiomeric cross-inhibition

The stability and conservation properties of a recently proposed polymerization model are studied. The achiral (racemic) solution is linearly unstable once the relevant control parameter (here the fidelity of the catalyst) exceeds a critical value. The growth rate is calculated for different fidelity parameters and cross-inhibition rates. A chirality parameter is defined and shown to be conserved by the nonlinear terms of the model. Finally, a truncated version of the model is used to derive a set of two ordinary differential equations and it is argued that these equations are more realistic than those used in earlier models of that form.Comment: 20 pages, 6 figures, Orig. Life Evol. Biosph. (accepted

Annotating patient clinical records with syntactic chunks and named entities: the Harvey corpus

The free text notes typed by physicians during patient consultations contain valuable information for the study of disease and treatment. These notes are difficult to process by existing natural language analysis tools since they are highly telegraphic (omitting many words), and contain many spelling mistakes, inconsistencies in punctuation, and non-standard word order. To support information extraction and classification tasks over such text, we describe a de-identified corpus of free text notes, a shallow syntactic and named entity annotation scheme for this kind of text, and an approach to training domain specialists with no linguistic background to annotate the text. Finally, we present a statistical chunking system for such clinical text with a stable learning rate and good accuracy, indicating that the manual annotation is consistent and that the annotation scheme is tractable for machine learning