2,814 research outputs found

    Hydrogeochemical Characterization of Groundwater in the Outaouais Region (Quebec, Canada)-A Regional Scale Study

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    As part of the Québec regional groundwater characterization program (PACES), a detailed groundwater quality survey was undertaken in the Outaouais Region (Québec, Canada). During the summers of 2011 and 2012, 139 samples were taken from municipal and private wells which were analysed for major ions, nutrients, metals and sulphides. About 70% of the samples were obtained from bedrock wells, mainly in the Canadian Shield and the remainder from wells screened in Quaternary deposit aquifers. Analysis quality was evaluated by calculating the anion-cation balance. As a result, 127 samples with anion-cation charge balance errors within ±10 % were used for the determination of hydrogeochemical facies. The classification by facies is also supported by multivariate statistical analysis, namely Principal Component Analysis (PCA) and Hierarchical Clustering Analysis (HCA). The study has identified Champlain Sea invasion, cation exchange and freshwater recharge as the main geochemical processes affecting groundwater chemistry in this region

    The spatio-temporal mapping of epileptic networks: Combination of EEG–fMRI and EEG source imaging

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    Simultaneous EEG–fMRI acquisitions in patients with epilepsy often reveal distributed patterns of Blood Oxygen Level Dependant (BOLD) change correlated with epileptiform discharges. We investigated if electrical source imaging (ESI) performed on the interictal epileptiform discharges (IED) acquired during fMRI acquisition could be used to study the dynamics of the networks identified by the BOLD effect, thereby avoiding the limitations of combining results from separate recordings. Nine selected patients (13 IED types identified) with focal epilepsy underwent EEG–fMRI. Statistical analysis was performed using SPM5 to create BOLD maps. ESI was performed on the IED recorded during fMRI acquisition using a realistic head model (SMAC) and a distributed linear inverse solution (LAURA). ESI could not be performed in one case. In 10/12 remaining studies, ESI at IED onset (ESIo) was anatomically close to one BOLD cluster. Interestingly, ESIo was closest to the positive BOLD cluster with maximal statistical significance in only 4/12 cases and closest to negative BOLD responses in 4/12 cases. Very small BOLD clusters could also have clinical relevance in some cases. ESI at later time frame (ESIp) showed propagation to remote sources co-localised with other BOLD clusters in half of cases. In concordant cases, the distance between maxima of ESI and the closest EEG–fMRI cluster was less than 33 mm, in agreement with previous studies. We conclude that simultaneous ESI and EEG–fMRI analysis may be able to distinguish areas of BOLD response related to initiation of IED from propagation areas. This combination provides new opportunities for investigating epileptic networks

    Diffusion at constant speed in a model phase space

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    We reconsider the problem of diffusion of particles at constant speed and present a generalization of the Telegrapher process to higher dimensional stochastic media (d>1d>1), where the particle can move along 2d2^d directions. We derive the equations for the probability density function using the ``formulae of differentiation'' of Shapiro and Loginov. The model is an advancement over similiar models of photon migration in multiply scattering media in that it results in a true diffusion at constant speed in the limit of large dimensions.Comment: Final corrected version RevTeX, 6 pages, 1 figur

    Diffusing-Light Spectroscopies Beyond the Diffusion Limit: The Role of Ballistic Transport and Anisotropic Scattering

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    Diffuse transmission and diffusing-wave spectroscopy (DWS) can be used to probe the structure and dynamics of opaque materials such as colloids, foams, and sand. A crucial step is to model photon transport as a diffusion process. This approach is acceptable for optically thick samples, far into the limit of strong multiple scattering; however, it becomes increasingly inaccurate for thinner samples for several reasons. Here, we correct for two of these defects. By modeling photon propagation by a telegrapher equation with suitable boundary conditions, we can account for the ballistic transport of photons at finite speed between successive scattering events. By introducing a discontinuity in the photon concentration at the source point, and then averaging over a range of penetration depths, we can account for the fact that photons usually scatter anisotropically into the forward direction, rather than being completely randomized at each event. The accuracy of our approach is tested by comparison both with random walk computer simulations and with experiments on specially designed suspensions of polystyrene spheres. We find that our predictions extend the utility of diffuse transmission to slabs of all thicknesses and of DWS to slabs down to about two transport mean free paths

    Hydrogeochemical Characterization of Groundwater in the Outaouais Region (Quebec, Canada)-A Regional Scale Study

    Get PDF
    As part of the Québec regional groundwater characterization program (PACES), a detailed groundwater quality survey was undertaken in the Outaouais Region (Québec, Canada). During the summers of 2011 and 2012, 139 samples were taken from municipal and private wells which were analysed for major ions, nutrients, metals and sulphides. About 70% of the samples were obtained from bedrock wells, mainly in the Canadian Shield and the remainder from wells screened in Quaternary deposit aquifers. Analysis quality was evaluated by calculating the anion-cation balance. As a result, 127 samples with anion-cation charge balance errors within ±10 % were used for the determination of hydrogeochemical facies. The classification by facies is also supported by multivariate statistical analysis, namely Principal Component Analysis (PCA) and Hierarchical Clustering Analysis (HCA). The study has identified Champlain Sea invasion, cation exchange and freshwater recharge as the main geochemical processes affecting groundwater chemistry in this region

    Assortative mixing as a source of bias in epidemiological studies of sexually transmitted infections: the case of smoking and human papillomavirus

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    For studies examining risk factors of sexually transmitted infections (STIs), confounding can stem from characteristics of partners of study subjects, and persist after adjustment for the subjects’ individual-level characteristics. Two conditions that can result in confounding by the subjects’ partners are: (C1) partner choice is assortative by the risk factor examined and, (C2) sexual activity is associated with the risk factor. The objective of this paper is to illustrate the potential impact of the assortativity bias in studies examining STI risk factors, using smoking and human papillomavirus (HPV) as an example. We developed an HPV transmission-dynamic mathematical model in which we nested a cross-sectional study assessing the smoking–HPV association. In our base case, we assumed (1) no effect of smoking on HPV, and (2) conditions C1–C2 hold for smoking (based on empirical data). The assortativity bias caused an overestimation of the odds ratio (OR) in the simulated study after perfect adjustment for the subjects’ individual-level characteristics (adjusted OR 1·51 instead of 1·00). The bias was amplified by a lower basic reproductive number (R(0)), greater mixing assortativity and stronger association of smoking with sexual activity. Adjustment for characteristics of partners is needed to mitigate assortativity bias

    An ensemble-based approach for pumping optimization in an island aquifer considering parameter, observation and climate uncertainty

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    In coastal zones, a major objective of groundwater management is often to determine sustainable pumping rates which avoid well salinization. Understanding how model and climate uncertainties affect optimal management solutions is essential for providing groundwater managers with information about salinization risk and is facilitated by the use of optimization under uncertainty (OUU) methods. However, guidelines are missing for the widespread implementation of OUU in real-world coastal aquifers and for the incorporation of climate uncertainty into OUU approaches. An ensemble-based OUU approach was developed considering parameter, observation and climate uncertainty and was implemented in a real-world island aquifer in the Magdalen Islands (Quebec, Canada). A sharp-interface seawater intrusion model was developed using MODFLOW-SWI2 and a prior parameter ensemble was generated containing multiple equally plausible realizations. Ensemble-based history matching was conducted using an iterative ensemble smoother which yielded a posterior parameter ensemble conveying both parameter and observation uncertainty. Sea level and recharge ensembles were generated for the year 2050 and were then used to generate a predictive parameter ensemble conveying parameter, observation and climate uncertainty. Multi-objective OUU was then conducted, aiming to both maximize pumping rates and minimize the probability of well salinization. As a result, the optimal trade-off between pumping and the probability of salinization was quantified considering parameter, historical observation and future climate uncertainty simultaneously. The multi-objective, ensemble-based OUU led to optimal pumping rates that were very different from a previous deterministic OUU and close to the current and projected water demand for risk-averse stances. Incorporating climate uncertainty into the OUU was also critical since it reduced the maximum allowable pumping rates for users with a risk-averse stance. The workflow used tools adapted to very high-dimensional, nonlinear models and optimization problems to facilitate its implementation in a wide range of real-world settings.</p
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