Spin Needlets for Cosmic Microwave Background Polarization Data Analysis

Scalar wavelets have been used extensively in the analysis of Cosmic Microwave Background (CMB) temperature maps. Spin needlets are a new form of (spin) wavelets which were introduced in the mathematical literature by Geller and Marinucci (2008) as a tool for the analysis of spin random fields. Here we adopt the spin needlet approach for the analysis of CMB polarization measurements. The outcome of experiments measuring the polarization of the CMB are maps of the Stokes Q and U parameters which are spin 2 quantities. Here we discuss how to transform these spin 2 maps into spin 2 needlet coefficients and outline briefly how these coefficients can be used in the analysis of CMB polarization data. We review the most important properties of spin needlets, such as localization in pixel and harmonic space and asymptotic uncorrelation. We discuss several statistical applications, including the relation of angular power spectra to the needlet coefficients, testing for non-Gaussianity on polarization data, and reconstruction of the E and B scalar maps.Comment: Accepted for publication in Phys. Rev.

Electron Densities in the Lower Thermosphere From GUVI 135.6 nm Tomographic Inversions in Support of SpreadFEx

The SpreadFEx campaign was conducted with the goal of investigating potential neutral atmospheric dynamics influences in seeding plasma instabilities and bubbles extending to higher altitudes from September to November 2005, with primary measurements in Brazil. In this paper, we present the results of space-based UV and ground-based optical observations in support of this campaign. Specifically, we present multi-dimensional electron density images obtained tomographically from the 135.6 nm emissions measured by the GUVI instrument aboard the TIMED satellite that result from radiative recombination of O+ and compare those with the corresponding 630.0 nm OI images recorded in the Brazilian sector. The GUVI results provide altitude vs. longitude information on depleted regions in the ionospheric plasma density that are complementary to the single-height latitude-longitude images obtained with the airglow imager

The relationship between corruption and economic development : lessons from Zimbabwe’s public enterprises

Abstract: This research sought to understand the lessons that can be drawn from Zimbabwe’s public enterprises on the relationship between corruption and economic development. The researchers adopted a qualitative design based on purposively sampled state enterprises. Data were collected using focus group discussions (FGDs) and key informant interviews from the various stakeholders that included the government, civil society, academia and the private sector in Zimbabwe. Four FGDs were conducted while 14 key informant interviews were done face-to-face with the respondents. Data obtained from interviews and FGDs were analysed thematically. The paper affirms that, indeed, corruption does not only disadvantage the poor but strangles economic development, reduces social services and diverts investments in organisations important to the survival of the nation. In addition, the paper makes a valuable and unique contribution to the different stakeholders’ understanding of how their different concerns and interests are represented and negotiated for the sustainable economic transformation of any given country

The LYRA Instrument Onboard PROBA2: Description and In-Flight Performance

The Large Yield Radiometer (LYRA) is an XUV-EUV-MUV (soft X-ray to mid-ultraviolet) solar radiometer onboard the European Space Agency PROBA2 mission that was launched in November 2009. LYRA acquires solar irradiance measurements at a high cadence (nominally 20 Hz) in four broad spectral channels, from soft X-ray to MUV, that have been chosen for their relevance to solar physics, space weather and aeronomy. In this article, we briefly review the design of the instrument, give an overview of the data products distributed through the instrument website, and describe the way that data are calibrated. We also briefly present a summary of the main fields of research currently under investigation by the LYRA consortium

Evidence that soyasaponin Bb retards disease progression in a murine model of polycystic kidney disease

Evidence that soyasaponin Bb retards disease progression in a murine model of polycystic kidney disease.BackgroundWe reported a lessened cyst growth in the pcy mouse model of polycystic kidney disease (PKD) when mice were fed a soy protein isolate (SPI)–based diet and hypothesized that the soyasaponins may be associated with this therapeutic effect. The effects of feeding a saponin-enriched alcohol extract (SEAE) from SPI, an isoflavone- and saponin-enriched soy supplement (Novasoy 400®), or a 99.5% pure soyasaponin Bb powder on cyst growth are reported here.MethodsThe therapeutic effects of the soyasaponins were studied in 60-day-old male pcy mice in two separate, 90-day feeding trials. In the first study, mice were fed either a casein-based (control) diet, a diet in which SPI replaced the casein or the control diet supplemented with SEAE. In the second study, mice were fed the control diet unsupplemented or supplemented with either a soyasaponin- and isoflavone-enriched soy product (Novasoy 400®) or a 99.5% pure soyasaponin Bb powder.ResultsIn study 1, kidney weight, water content, and plasma creatinine and urea levels were markedly reduced in the SEAE-fed animals compared to tissues from the control group; likewise, mice fed the SPI-based diet showed a decreased plasma creatinine, but only a slightly reduced plasma urea. In study 2, kidney weight, water content, plasma creatinine and urea levels were significantly reduced in mice fed the soyasaponin Bb powder and the Novasoy-400® supplement, compared to controls.ConclusionSoyasaponin Bb can impede kidney enlargement and cyst growth in the pcy mouse model of PKD. Further studies are needed to determine its most effective dose and mechanism of action

Characterization of a 4H-SiC High Power Density Controlled Current Limiter

International audienceCritical steps for the fabrication of SiC devices are thermal annealing and metal ohmic contact formation. Metal annealing effect on the electrical characteristics of the current limiter underlines the necessity to control this device fabrication step. Measurements of contact resistivity as a function of temperature demonstrate the stability of the N type Ni/SiC contact in the range of 175 K-450 K as its value remains constant around 40 µΩ.cm 2. Post implantation annealing effect on the sheet resistance (Rsh) shows that a 1700°C/30 min annealing gives better trade off in terms of dopant activation and surface roughness. High power density has been measured up to 600 V. Current thermal stability has been measured for an applied drain to source voltage of 100 V and exhibits high power density capabilities of SiC VJFET as a controlled current limiter. Introduction

Rituximab therapy for refractory interstitial lung disease related to antisynthetase syndrome

SummaryObjectiveTo report our experience using rituximab as therapy for refractory antisynthetase syndrome (ASS)-associated interstitial lung disease.MethodsWe retrospectively evaluated the medical records of 7 ASS patients with refractory interstitial lung disease, which had previously failed to respond to prednisone and/or other cytotoxic drugs. All 7 patients received rituximab therapy, i.e.: 1 g at days 0 and 14 and at 6-month follow-up. Data on pulmonary symptoms, pulmonary function tests and high resolution computed tomography (HRCT) scan of the lungs were collected: 1) before rituximab initiation; and 2) at 6-month and one-year follow-up after the first infusion of rituximab.ResultsAt one-year follow-up, ASS patients had resolution (n = 2) or improvement of pulmonary clinical manifestations. Patients also exhibited significant improvement of interstitial lung disease parameters: 1) on pulmonary function tests: FVC (p = 0.03) and DLCO (p = 2 × 10−5); 2) and HRCT-scan of the lungs. Due to clinical resolution/improvement of interstitial lung disease, the median daily dose of oral prednisone could be reduced in these 7 ASS patients at one-year follow-up, compared with baseline (20 mg/day vs. 9 mg/day; p = 0.015).ConclusionOur findings suggest that rituximab may be a helpful therapy for refractory interstitial lung disease in patients with ASS

Silicon Carbide Controlled Current Limiter, Current Limitation Strategies, Foreseen Applications and Benefits

International audienceThe expansion of electricity networks (distribution of energy, telecommunication), strongly contributed to increase the risks of appearance of defects, such as surge or overload. This multiplicity and complexity of electric networks, the need to have reliable systems favoured the development of serial protection devices. Fuse solution allows an efficient and total protection but requires to replace an element in case of failure. Therefore, other solutions have been investigated. Complex systems have been developed, all based on serial compensation, such as supra-conductor material, GTO MOV combination ... Indeed, because of the strong energy appearance during a short circuit, it is necessary to limit and to dissipate the energy of the short circuit, under high bias. This constraint leads to a feasibility study of a current limiter in 4H silicon carbide (4H-SiC). A VJFET structure was retained focusing on a nominal current of IN = 1 A and a nominal voltage of VN = 690 V. The device was optimised, taking into account SiC excellent physical properties. The VJFET was designed checking the trade-off between a low on-resistance value, high voltage capability and the highest gate transconductance value. A first batch of component was made, validating the bi-directional limitation function in both current and voltage mode, (VMAX = 970 V). The efficiency of the protection was validated, demonstrating the capacity of a component to react very quickly (t < 1 µs). Using such a device is very suitable in several applications (protection against short circuit, transient over current…) as it will allow to reduce transient phenomena and thus increase the efficiency and lifetime of the whole system

Chemical and dynamical processes in the mesospheric emissive layer. First results of stereoscopic observations

[1] The mesospheric emissive layer is an efficient tracer of the dynamical processes propagating in the atmosphere at that level. CCD images in the near infrared taken from the ground at slant angles often reveal the existence of wavy fields. A series of such images has been transformed, using matrix operations, producing a downward satellite-type view that covers a circular area of radius ∼1000 km at the altitude of the layer. The Fourier characteristics of the wave system are measured using a Morlet-type wavelet generator function with horizontal wavelengths of mostly ∼20–40 km and 100–150 km and temporal periods of ∼15–30 min. An oxygen-hydrogen model is used to evaluate the response of the emissive layer to a progressive density wave. The altitude of the layer is modulated with an amplitude of ∼0.8–1.8 km when a density wave propagates vertically. The layer thickness is slightly modulated and is equal to ∼7 km. Stereoscopic pairs of photographs taken simultaneously on 8–9 September 2000 at the Château-Renard and Pic du Midi observatories are used to obtain surface maps of the emission layer barycenter altitude. A stereocorrelation method suitable for low contrast objects without discrete contours is employed. Preliminary results for areas ∼50 × 50 km2 are presented. The surface maps of the layer barycenter altitude depict the existence of waves. They show the same wavy structure and compare favorably with the maps showing the emission intensity