4,479 research outputs found
Computer program for compressible flow network analysis
Program solves problem of an arbitrarily connected one dimensional compressible flow network with pumping in the channels and momentum balancing at flow junctions. Program includes pressure drop calculations for impingement flow and flow through pin fin arrangements, as currently found in many air cooled turbine bucket and vane cooling configurations
Performance evaluation of the Boron Coated Straws detector with Geant4
The last decade has witnessed the development of several alternative neutron
detector technologies, as a consequence of upcoming neutron sources and
upgrades, as well the world-wide shortage of He. One branch of development
is the family of B-based gaseous detectors. This work focuses on the
boron coated straws (BCS) by Proportional Technologies Inc., a commercial
solution designed for use in homeland security and neutron science. A detailed
Geant4 simulation study of the BCS is presented, which investigates various
aspects of the detector performance, e.g. efficiency, activation, absorption
and the impact of scattering on the measured signal. The suitability of the BCS
detector for Small Angle Neutron Scattering (SANS), direct chopper spectrometry
and imaging is discussed.Comment: 50 pages, 37 figures, minor changes after review, results unchange
Ligand-based virtual screening using binary kernel discrimination
This paper discusses the use of a machine-learning technique called binary kernel discrimination (BKD) for virtual screening in drug- and pesticide-discovery programmes. BKD is compared with several other ligand-based tools for virtual screening in databases of 2D structures represented by fragment bit-strings, and is shown to provide an effective, and reasonably efficient, way of prioritising compounds for biological screening
Scaffold searching: automated identification of similar ring systems for the design of combinatorial libraries
Rigid ring systems can be used to position receptor-binding functional groups in 3D space and they thus play an increasingly important role in the design of combinatorial libraries. This paper discusses the use of shape-similarity methods to identify ring systems that are structurally similar to, and aligned with, a user-defined target ring system. These systems can be used as alternative scaffolds for the construction of a combinatorial library
Phase Change Material (PCM) thermal stores
The application of inorganic Phase Change Material thermal stores in sustainable building design in Europe – an on-going research project
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