143 research outputs found
Community owned trading enterprises : their uniqueness and performance : a thesis submitted in partial fulfilment of the requirements for the degree of Master of Business Studies at Massey University
Community ownership of trading enterprises has not been so favoured as a concept during the latter part of the 20th
century as successive New Zealand Governments pursued market forces policies. The face of the New Zealand public ownership business scene radically changed from the mid 1980's as telecommunications, railways, the ports, Coal Corp, energy ... were all restructured in pursuit of the market model. Why was the public or community ownership model apparently not supported? The empirical evidence did not unequivocally uphold privatisation and the market model as being inherently more efficient as a structure. Notably also, community ownership was much enjoyed as a concept. This research, therefore, looks at the concept of community ownership and seeks to define its uniqueness and identify its performance in operating trading enterprises. The electricity companies in New Zealand were the area selected. The results moderately support the view that social/community goals are of more importance to community owned trading enterprises than their private ownership equivalents. Notably community ownership outperformed private enterprise as measured by ROE and ROA. Thus the contention that community ownership as a concept had much to offer, and was not inherently less efficient, was not disproved by this research. Further research in other fields is worthy of pursuit
A new hybrid metric for verifying parallel corpora of Arabic-English
This paper discusses a new metric that has been applied to verify the quality
in translation between sentence pairs in parallel corpora of Arabic-English.
This metric combines two techniques, one based on sentence length and the other
based on compression code length. Experiments on sample test parallel
Arabic-English corpora indicate the combination of these two techniques
improves accuracy of the identification of satisfactory and unsatisfactory
sentence pairs compared to sentence length and compression code length alone.
The new method proposed in this research is effective at filtering noise and
reducing mis-translations resulting in greatly improved quality.Comment: in CCSEA-201
Handwritten digit recognition by bio-inspired hierarchical networks
The human brain processes information showing learning and prediction
abilities but the underlying neuronal mechanisms still remain unknown.
Recently, many studies prove that neuronal networks are able of both
generalizations and associations of sensory inputs. In this paper, following a
set of neurophysiological evidences, we propose a learning framework with a
strong biological plausibility that mimics prominent functions of cortical
circuitries. We developed the Inductive Conceptual Network (ICN), that is a
hierarchical bio-inspired network, able to learn invariant patterns by
Variable-order Markov Models implemented in its nodes. The outputs of the
top-most node of ICN hierarchy, representing the highest input generalization,
allow for automatic classification of inputs. We found that the ICN clusterized
MNIST images with an error of 5.73% and USPS images with an error of 12.56%
Artificial Sequences and Complexity Measures
In this paper we exploit concepts of information theory to address the
fundamental problem of identifying and defining the most suitable tools to
extract, in a automatic and agnostic way, information from a generic string of
characters. We introduce in particular a class of methods which use in a
crucial way data compression techniques in order to define a measure of
remoteness and distance between pairs of sequences of characters (e.g. texts)
based on their relative information content. We also discuss in detail how
specific features of data compression techniques could be used to introduce the
notion of dictionary of a given sequence and of Artificial Text and we show how
these new tools can be used for information extraction purposes. We point out
the versatility and generality of our method that applies to any kind of
corpora of character strings independently of the type of coding behind them.
We consider as a case study linguistic motivated problems and we present
results for automatic language recognition, authorship attribution and self
consistent-classification.Comment: Revised version, with major changes, of previous "Data Compression
approach to Information Extraction and Classification" by A. Baronchelli and
V. Loreto. 15 pages; 5 figure
Homosexuality, religion and the contested legal framework governing sex education in England
Differences between Human Plasma and Serum Metabolite Profiles
BACKGROUND: Human plasma and serum are widely used matrices in clinical and biological studies. However, different collecting procedures and the coagulation cascade influence concentrations of both proteins and metabolites in these matrices. The effects on metabolite concentration profiles have not been fully characterized. METHODOLOGY/PRINCIPAL FINDINGS: We analyzed the concentrations of 163 metabolites in plasma and serum samples collected simultaneously from 377 fasting individuals. To ensure data quality, 41 metabolites with low measurement stability were excluded from further analysis. In addition, plasma and corresponding serum samples from 83 individuals were re-measured in the same plates and mean correlation coefficients (r) of all metabolites between the duplicates were 0.83 and 0.80 in plasma and serum, respectively, indicating significantly better stability of plasma compared to serum (p = 0.01). Metabolite profiles from plasma and serum were clearly distinct with 104 metabolites showing significantly higher concentrations in serum. In particular, 9 metabolites showed relative concentration differences larger than 20%. Despite differences in absolute concentration between the two matrices, for most metabolites the overall correlation was high (mean r = 0.81±0.10), which reflects a proportional change in concentration. Furthermore, when two groups of individuals with different phenotypes were compared with each other using both matrices, more metabolites with significantly different concentrations could be identified in serum than in plasma. For example, when 51 type 2 diabetes (T2D) patients were compared with 326 non-T2D individuals, 15 more significantly different metabolites were found in serum, in addition to the 25 common to both matrices. CONCLUSIONS/SIGNIFICANCE: Our study shows that reproducibility was good in both plasma and serum, and better in plasma. Furthermore, as long as the same blood preparation procedure is used, either matrix should generate similar results in clinical and biological studies. The higher metabolite concentrations in serum, however, make it possible to provide more sensitive results in biomarker detection
Mass-spectrometry-based metabolomics: limitations and recommendations for future progress with particular focus on nutrition research
Mass spectrometry (MS) techniques, because of their sensitivity and selectivity, have become methods of choice to characterize the human metabolome and MS-based metabolomics is increasingly used to characterize the complex metabolic effects of nutrients or foods. However progress is still hampered by many unsolved problems and most notably the lack of well established and standardized methods or procedures, and the difficulties still met in the identification of the metabolites influenced by a given nutritional intervention. The purpose of this paper is to review the main obstacles limiting progress and to make recommendations to overcome them. Propositions are made to improve the mode of collection and preparation of biological samples, the coverage and quality of mass spectrometry analyses, the extraction and exploitation of the raw data, the identification of the metabolites and the biological interpretation of the results
Evaluation and Characterization of Bacterial Metabolic Dynamics with a Novel Profiling Technique, Real-Time Metabolotyping
BACKGROUND: Environmental processes in ecosystems are dynamically altered by several metabolic responses in microorganisms, including intracellular sensing and pumping, battle for survival, and supply of or competition for nutrients. Notably, intestinal bacteria maintain homeostatic balance in mammals via multiple dynamic biochemical reactions to produce several metabolites from undigested food, and those metabolites exert various effects on mammalian cells in a time-dependent manner. We have established a method for the analysis of bacterial metabolic dynamics in real time and used it in combination with statistical NMR procedures. METHODOLOGY/PRINCIPAL FINDINGS: We developed a novel method called real-time metabolotyping (RT-MT), which performs sequential (1)H-NMR profiling and two-dimensional (2D) (1)H, (13)C-HSQC (heteronuclear single quantum coherence) profiling during bacterial growth in an NMR tube. The profiles were evaluated with such statistical methods as Z-score analysis, principal components analysis, and time series of statistical TOtal Correlation SpectroScopY (TOCSY). In addition, using 2D (1)H, (13)C-HSQC with the stable isotope labeling technique, we observed the metabolic kinetics of specific biochemical reactions based on time-dependent 2D kinetic profiles. Using these methods, we clarified the pathway for linolenic acid hydrogenation by a gastrointestinal bacterium, Butyrivibrio fibrisolvens. We identified trans11, cis13 conjugated linoleic acid as the intermediate of linolenic acid hydrogenation by B. fibrisolvens, based on the results of (13)C-labeling RT-MT experiments. In addition, we showed that the biohydrogenation of polyunsaturated fatty acids serves as a defense mechanism against their toxic effects. CONCLUSIONS: RT-MT is useful for the characterization of beneficial bacterium that shows potential for use as probiotic by producing bioactive compounds
- …