270 research outputs found
Modulation of torque evoked by wide-pulse, high-frequency neuromuscular electrical stimulation and the potential implications for rehabilitation and training
The effectiveness of neuromuscular electrical stimulation (NMES) for rehabilitation is proportional to the evoked torque. The progressive increase in torque (extra torque) that may develop in response to low intensity wide-pulse high-frequency (WPHF) NMES holds great promise for rehabilitation as it overcomes the main limitation of NMES, namely discomfort. WPHF NMES extra torque is thought to result from reflexively recruited motor units at the spinal level. However, whether WPHF NMES evoked force can be modulated is unknown. Therefore, we examined the effect of two interventions known to change the state of spinal circuitry in opposite ways on evoked torque and motor unit recruitment by WPHF NMES. The interventions were high-frequency transcutaneous electrical nerve stimulation (TENS) and anodal transcutaneous spinal direct current stimulation (tsDCS). We show that TENS performed before a bout of WPHF NMES results in lower evoked torque (median change in torque time-integral: − 56%) indicating that WPHF NMES-evoked torque might be modulated. In contrast, the anodal tsDCS protocol used had no effect on any measured parameter. Our results demonstrate that WPHF NMES extra torque can be modulated and although the TENS intervention blunted extra torque production, the finding that central contribution to WPHF NMES-evoked torques can be modulated opens new avenues for designing interventions to enhance WPHF NMES
O agir econômico como motor da política de saúde na Alemanha: consequências para a prevenção e promoção da saúde
The Evolution of Cognitive Load Theory and the Measurement of Its Intrinsic, Extraneous and Germane Loads: A Review
Cognitive Load Theory has been conceived for supporting instructional design through the use of the construct of cognitive load. This is believed to be built upon three types of load: intrinsic, extraneous and germane. Although Cognitive Load Theory and its assumptions are clear and well-known, its three types of load have been going through a continuous investigation and re-definition. Additionally, it is still not clear whether these are independent and can be added to each other towards an overall measure of load. The purpose of this research is to inform the reader about the theoretical evolution of Cognitive Load Theory as well as the measurement techniques and measures emerged for its cognitive load types. It also synthesises the main critiques of scholars and the scientific value of the theory from a rationalist and structuralist perspective
The financial crisis and health care systems in Europe: universal care under threat? Trends in health sector reforms in Germany, the United Kingdom, and Spain
Another Solution to the Problem of Theoretical Terms
In this paper, a solution to the problem of theoretical terms is developed that is based on Carnap's doctrine of indirect interpretation of theoretical terms. This doctrine will be given a semantic, model-theoretic explanation that is not given by Carnap himself as he remains content with a syntactic explanation. From that semantic explanation, rules for the truth-value assignment to postulates, i.\,e.\ sentences that determine the meaning of theoretical terms, are derived. The logical status of postulates will be clarified thereby in such a way that the problem of theoretical terms disappears
The brake within: mechanisms of intrinsic regulation of axon growth featuring the CDH1-APC pathway
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