World Scientists’ Warning of a Climate Emergency

Scientists have a moral obligation to clearly warn humanity of any catastrophic threat and to “tell it like it is.” On the basis of this obligation and the graphical indicators presented below, we declare, with more than 11,000 scientist signatories from around the world, clearly and unequivocally that planet Earth is facing a climate emergency

Soybean Chlorosis Studies on High pH Bottomland Soils

Soybean varieties are different in tolerance to lime-induced chlorosis. Field trials were conducted to evaluate variety performance on soils where chlorosis in soybeans was a known problem. Thirty-six varieties out of 177 were identified as tolerant to soil conditions that cause chlorosis. Eleven varieties of these 36 were found to have the most consistent yield performance on high pH soils. Tolerant varieties must be planted at adequate densities for best performance. A seeding rate of 13.5 seeds per foot of row, the highest seeding rate employed, did not appear to maximize yield on soils where chlorosis was severe. On some soils, chlorosis is so severe that even tolerant varieties planted at adequate densities will not produce seed. Under conditions where soils cause moderate to severe chlorosis in tolerant varieties, yields were improved by the use of a high pH stable chelate (Fe-EDDHA) with the seed

Soybean Chlorosis Studies on High pH Bottomland Soils

Soybean varieties are different in tolerance to lime-induced chlorosis. Field trials were conducted to evaluate variety performance on soils where chlorosis in soybeans was a known problem. Thirty-six varieties out of 177 were identified as tolerant to soil conditions that cause chlorosis. Eleven varieties of these 36 were found to have the most consistent yield performance on high pH soils. Tolerant varieties must be planted at adequate densities for best performance. A seeding rate of 13.5 seeds per foot of row, the highest seeding rate employed, did not appear to maximize yield on soils where chlorosis was severe. On some soils, chlorosis is so severe that even tolerant varieties planted at adequate densities will not produce seed. Under conditions where soils cause moderate to severe chlorosis in tolerant varieties, yields were improved by the use of a high pH stable chelate (Fe-EDDHA) with the seed

Prehospital neurological deterioration in stroke

BACKGROUND AND PURPOSE: Patients with stroke can experience neurological deterioration in the prehospital setting. We evaluated patients with stroke to determine factors associated with prehospital neurological deterioration (PND). METHODS: Among the Greater Cincinnati/Northern Kentucky region (population ~1.3 million), we screened all 15 local hospitals' admissions from 2010 for acute stroke and included patients aged ≥20. The GCS was compared between emergency medical services (EMS) arrival and hospital arrival, with decrease ≥2 points considered PND. Data obtained retrospectively included demographics, medical history and medication use, stroke subtype (eg, ischaemic stroke (IS), intracerebral haemorrhage (ICH), subarachnoid haemorrhage (SAH)) and IS subtype (eg, small vessel, large vessel, cardioembolic), seizure at onset, time intervals between symptom onset, EMS arrival and hospital arrival, EMS level of training, and blood pressure and serum glucose on EMS arrival. RESULTS: Of 2708 total patients who had a stroke, 1092 patients (median (IQR) age 74 (61-83) years; 56% women; 21% black) were analysed. PND occurred in 129 cases (12%), including 9% of IS, 24% of ICH and 16% of SAH. In multivariable analysis, black race, atrial fibrillation, haemorrhagic subtype and ALS level of transport were associated with PND. CONCLUSION: Haemorrhage and atrial fibrillation is associated with PND in stroke, and further investigation is needed to establish whether PND can be predicted. Further studies are also needed to assess whether preferential transport of patients with deterioration to hospitals equipped with higher levels of care is beneficial, identify why race is associated with deterioration and to test therapies targeting PND

Practice patterns for acute ischemic stroke workup: A longitudinal population‐based study

Background We examined practice patterns of inpatient testing to identify stroke etiologies and treatable risk factors for acute ischemic stroke recurrence. Methods and Results We identified stroke cases and related diagnostic testing from four 1‐year study periods (July 1993 to June 1994, 1999, 2005, and 2010) of the Greater Cincinnati/Northern Kentucky Stroke Study. Patients aged ≥18 years were included. We focused on evaluation of extracranial arteries for carotid stenosis and assessment of atrial fibrillation because randomized controlled trials supported treatment of these conditions for stroke prevention across all 4 study periods. In each study period, we also recorded stroke etiology, as determined by diagnostic testing and physician adjudication. An increasing proportion of stroke patients received assessment of both extracranial arteries and the heart over time (50%, 58%, 74%, and 78% in the 1993–1994, 1999, 2005, and 2010 periods, respectively; P &lt;0.0001 for trend), with the most dramatic individual increases in echocardiography (57%, 63%, 77%, and 83%, respectively). Concurrently, we observed a decrease in strokes of unknown etiology (47%, 48%, 41%, and 38%, respectively; P &lt;0.0001 for trend). We also found a significant increase in strokes of other known causes (32%, 25%, 45% and 59%, respectively; P &lt;0.0001 for trend). Conclusions Stroke workup for treatable causes of stroke are being used more frequently over time, and this is associated with a decrease in cryptogenic strokes. Future study of whether better determination of treatable stroke etiologies translates to a decrease in stroke recurrence at the population level will be essential. </jats:sec

G92-1071 Ridge Plant Systems: Weed Control

Advantages and disadvantages of the ridge plant system, weed control before and at planting and economics of the system are discussed. Ridge planting combines tillage and herbicides to achieve improved weed control in row crops. Crop seed is planted into ridges formed during cultivation and/or ditching of the previous crop. In ridge planting, the planter follows the old row and ridge clearing sweeps or disks move the surface soil, residue and much of the weed seed out of the row. Weed seeds are deposited between the rows where, upon germination, they can be controlled with cultivation. Two cultivations are generally used for weed control. The first cultivation loosens the soil and the second rebuilds the ridge. The ridge plant system is well suited to furrow-irrigationd crops. It also works well with dryland crops or those under center pivot irrigation. On furrow irrigationd land, corn or sorghum stalks may need to be shredded to assist in decomposition and hence irrigation because crop residue slows water advance in the furrow. Slowing the water may be a benefit, however, on soils which have a low water intake rate. With center pivot and dryland acres the need for shredding depends on how much residue the cultivator can handle

G92-1071 Ridge Plant Systems: Weed Control

Advantages and disadvantages of the ridge plant system, weed control before and at planting and economics of the system are discussed. Ridge planting combines tillage and herbicides to achieve improved weed control in row crops. Crop seed is planted into ridges formed during cultivation and/or ditching of the previous crop. In ridge planting, the planter follows the old row and ridge clearing sweeps or disks move the surface soil, residue and much of the weed seed out of the row. Weed seeds are deposited between the rows where, upon germination, they can be controlled with cultivation. Two cultivations are generally used for weed control. The first cultivation loosens the soil and the second rebuilds the ridge. The ridge plant system is well suited to furrow-irrigationd crops. It also works well with dryland crops or those under center pivot irrigation. On furrow irrigationd land, corn or sorghum stalks may need to be shredded to assist in decomposition and hence irrigation because crop residue slows water advance in the furrow. Slowing the water may be a benefit, however, on soils which have a low water intake rate. With center pivot and dryland acres the need for shredding depends on how much residue the cultivator can handle

Characterization of Ceriporiopsis subvermispora Bicupin Oxalate Oxidase Expressed in Pichia pastoris

Oxalate oxidase (E.C. 1.2.3.4) catalyzes the oxygen-dependent oxidation of oxalate to carbon dioxide in a reaction that is coupled with the formation of hydrogen peroxide. Although there is currently no structural information available for oxalate oxidase fromCeriporiopsis subvermispora (CsOxOx), sequence data and homology modeling indicate that it is the first manganese-containing bicupin enzyme identified that catalyzes this reaction. Interestingly, CsOxOx shares greatest sequence homology with bicupin microbial oxalate decarboxylases (OxDC). We show that CsOxOx activity directly correlates with Mn content and other metals do not appear to be able to support catalysis. EPR spectra indicate that the Mn is present as Mn(II), and are consistent with the coordination environment expected from homology modeling with known X-ray crystal structures of OxDC from Bacillus subtilis. EPR spin-trapping experiments support the existence of an oxalate-derived radical species formed during turnover. Acetate and a number of other small molecule carboxylic acids are competitive inhibitors for oxalate in the CsOxOx catalyzed reaction. The pH dependence of this reaction suggests that the dominant contribution to catalysis comes from the monoprotonated form of oxalate binding to a form of the enzyme in which an active site carboxylic acid residue must be unprotonated

World scientists’ warnings into action, local to global

‘We have kicked the can down the road once again – but we are running out of road.’ – Rachel Kyte, Dean of Fletcher School at Tufts University. We, in our capacities as scientists, economists, governance and policy specialists, are shifting from warnings to guidance for action before there is no more ‘road.’ The science is clear and irrefutable; humanity is in advanced ecological overshoot. Our overexploitation of resources exceeds ecosystems’ capacity to provide them or to absorb our waste. Society has failed to meet clearly stated goals of the UN Framework Convention on Climate Change. Civilization faces an epochal crossroads, but with potentially much better, wiser outcomes if we act now. What are the concrete and transformative actions by which we can turn away from the abyss? In this paper we forcefully recommend priority actions and resource allocation to avert the worst of the climate and nature emergencies, two of the most pressing symptoms of overshoot, and lead society into a future of greater wellbeing and wisdom. Humanity has begun the social, economic, political and technological initiatives needed for this transformation. Now, massive upscaling and acceleration of these actions and collaborations are essential before irreversible tipping points are crossed in the coming decade. We still can overcome significant societal, political and economic barriers of our own making. Previously, we identified six core areas for urgent global action – energy, pollutants, nature, food systems, population stabilization and economic goals. Here we identify an indicative, systemic and time-limited framework for priority actions for policy, planning and management at multiple scales from household to global. We broadly follow the ‘Reduce-Remove-Repair’ approach to rapid action. To guide decision makers, planners, managers, and budgeters, we cite some of the many experiments, mechanisms and resources in order to facilitate rapid global adoption of effective solutions. Our biggest challenges are not technical, but social, economic, political and behavioral. To have hope of success, we must accelerate collaborative actions across scales, in different cultures and governance systems, while maintaining adequate social, economic and political stability. Effective and timely actions are still achievable on many, though not all fronts. Such change will mean the difference for billions of children and adults, hundreds of thousands of species, health of many ecosystems, and will determine our common future

World scientists' warnings into action, local to global

‘We have kicked the can down the road once again – but we are running out of road.’ – Rachel Kyte, Dean of Fletcher School at Tufts University. We, in our capacities as scientists, economists, governance and policy specialists, are shifting from warnings to guidance for action before there is no more ‘road.’ The science is clear and irrefutable; humanity is in advanced ecological overshoot. Our over exploitation of resources exceeds ecosystems’capacity to provide them or to absorb our waste. Society has failed to meet clearly stated goals of the UN Framework Convention on Climate Change. Civilization faces an epochal crossroads, but with potentially much better, wiser outcomes if we act now. What are the concrete and transformative actions by which we can turn away from the abyss? In this paper we forcefully recommend priority actions and resource allocation to avert the worst of the climate and nature emergencies, two of the most pressing symptoms of overshoot, and lead society into a future of greater wellbeing and wisdom. Humanity has begun the social, economic, political and technological initiatives needed for this transformation. Now, massive upscaling and acceleration of these actions and collaborations are essential before irreversible tipping points are crossed in the coming decade. We still can overcome significant societal, political and economic barriers of our own making. Previously, we identified six core areas for urgent global action – energy, pollutants, nature, food systems, population stabilization and economic goals. Here we identify an indicative, systemic and time-limited framework for priority actions for policy, planning and management at multiple scales from household to global. We broadly follow the ‘Reduce-Remove-Repair’ approach to rapid action. To guide decision makers, planners, managers, and budgeters, we cite some of the many experiments, mechanisms and resources in order to facilitate rapid global adoption of effective solutions. Our biggest challenges are not technical, but social, economic, political and behavioral. To have hope of success, we must accelerate collaborative actions across scales, in different cultures and governance systems, while maintaining adequate social, economic and political stability. Effective and timely actions are still achievable on many, though not all fronts. Such change will mean the difference for billions of children and adults, hundreds of thousands of species, health of many ecosystems, and will determine our common future