New geoelectrical characterization of a continental collision zone in the Central - Eastern Pyrenees: Constraints from 3-D joint inversion of electromagnetic data

Continent-continent collisions are responsible for the formation of large mountain ranges like the Himalayas and the Alps and play a primary role in the development of the continents. The continental collision between the Iberian and European plates during the Alpine Orogeny resulted in the formation of the Pyrenees. In this study new electromagnetic data from the Eastern Pyrenees were complemented with older data from the Central Pyrenees, constraining the physical and geological processes at the eastern end of the Pyrenean mountain range. The electrical resistivity distribution beneath the Central-Eastern Pyrenees was characterized by means of three-dimensional (3-D) joint inversion of three electromagnetic datasets: (1) the MT impedance tensor (Z), (2) the geomagnetic transfer function (T), and (3) the inter-station horizontal magnetic transfer function (H). The main finding was the non-continuity to the east of the major conductive anomaly observed previously beneath the Central and West-Central Pyrenees related to partial melting of the Iberian subducted lower crust. Lower amounts of water (related to the presence of muscovite and biotite) in the subducted lower crust beneath the Eastern Pyrenees were suggested to explain the lack of partial melting in this part of the mountain range. The electrical resistivity model also revealed higher electrical resistivity values for the lithospheric mantle beneath the Eastern Pyrenees than beneath the Central Pyrenees, thus supporting the hypothesis of an heterogeneous Iberian plate inherited from the Variscan Orogeny. A less clear signature was the lateral variation along the strike direction of the lithosphere-asthenosphere boundary beneath the Eastern Pyrenees (relatively flat, between 110 km and 140 km depth) and the Central Pyrenees (north dipping, between 80 km and 120 km depth beneath the Iberian Plate and between 110 km and 160 km depth beneath the European plate), supporting the hypothesis of a missing lithospheric root beneath the Eastern Pyrenees

Prospective individual patient data meta-analysis of two randomized trials on convalescent plasma for COVID-19 outpatients

Data on convalescent plasma (CP) treatment in COVID-19 outpatients are scarce. We aimed to assess whether CP administered during the first week of symptoms reduced the disease progression or risk of hospitalization of outpatients. Two multicenter, double-blind randomized trials (NCT04621123, NCT04589949) were merged with data pooling starting when = 50 years and symptomatic for <= 7days were included. The intervention consisted of 200-300mL of CP with a predefined minimum level of antibodies. Primary endpoints were a 5-point disease severity scale and a composite of hospitalization or death by 28 days. Amongst the 797 patients included, 390 received CP and 392 placebo; they had a median age of 58 years, 1 comorbidity, 5 days symptoms and 93% had negative IgG antibody-test. Seventy-four patients were hospitalized, 6 required mechanical ventilation and 3 died. The odds ratio (OR) of CP for improved disease severity scale was 0.936 (credible interval (CI) 0.667-1.311); OR for hospitalization or death was 0.919 (CI 0.592-1.416). CP effect on hospital admission or death was largest in patients with <= 5 days of symptoms (OR 0.658, 95%CI 0.394-1.085). CP did not decrease the time to full symptom resolution

Impacto de la COVID-19 en la salud mental de la población: estudio en atención primaria

Resumen: Objetivo: Principales: determinar la prevalencia y las características de los pacientes con COVID-19, y la incidencia del trastorno mental asociado a la infección y los factores de riesgo. Secundarios: conocer la prevalencia y las características de los afectados de COVID persistente. Diseño: Estudio de incidencia del trastorno mental en los pacientes diagnosticados de COVID-19, y estudio de casos y controles del síndrome de COVID persistente en la submuestra de pacientes diagnosticados de COVID-19, sin antecedente de trastorno mental. Emplazamiento: Atención Primaria de la Región Sanitaria de Lleida. Participantes: Se incluyeron 46.258 pacientes diagnosticados de COVID-19 sin antecedente de trastorno mental. Mediciones principales: La variable dependiente fue el desarrollo de trastorno mental (ansiedad, trastorno del estado de ánimo, trastorno adaptativo e insomnio) en el periodo de estudio (11/03/2020 a 11/03/2022) y las independientes variables clínicas y sociofamiliares. Se analizó su asociación con el desarrollo del trastorno mental mediante el cálculo de las hazard ratio ajustadas a un modelo de regresión logística. Resultados: La edad media ± desviación estándar de los 46.258 pacientes incluidos fue de 43 ± 17,9 años. El 47% eran mujeres. El 3,46% desarrollaron algún trastorno mental (59,20% ansiedad). El síndrome de «COVID persistente» se manifestó más en las mujeres de edad mayor, sin hábitos tóxicos, con obesidad y comorbilidad asociada. Conclusiones: La COVID-19 ha generado impacto en la salud mental de los pacientes. Conocer los factores de riesgo para los trastornos mentales y para el síndrome de «COVID persistente» permitiría al clínico identificar a los pacientes susceptibles de recibir medidas preventivas y evitar su aparición. Abstract: Objective: To determine the prevalence of COVID-19 and the characteristics of infected patients, as well as the prevalence of mental disorders associated with the infection and the associated risk factors. Secondary: to know the prevalence of the long COVID syndrome and the characteristics of this cohort. Design: Incidence study of mental disorder in patients diagnosed with COVID-19 and case-control study of long COVID syndrome in the subsample of patients diagnosed with COVID-19 without a history of mental disorder. Site: Primary care setting in Lleida. Participants: The 46,258 patients diagnosed of COVID-19 without a history of mental disorder were followed for 2 years. Main measurements: The dependent variable was the mental disorder in the period 03/11/2020 to 03/11/2022; and the independent variables were clinical and social variables. Its association with mental disorder was analyzed by calculating the adjusted hazard ratio using a logistic regression model. Results: The average age of 46,258 patients at the beginning of the study was 43 ± 17.9 years. 47% were women. The mental disorder rate for all period was 3.46% (59.20% anxiety). A predictive score was elaborated. The long COVID syndrome was more common in older women, without toxic habits, with obesity and associated comorbidity. Conclusions: COVID-19 has had an impact on the mental health of patients. Knowing the risk factors for developing these mental disorders and the long COVID syndrome would allow the clinician to be able to identify patients at risk in order to establish preventive measures and avoid their appearance

Publicaciones del Instituto de Biología Aplicada. Tomos 27-28

[Tomo 27] JUAN GÓMEZ-MENOR ORTEGA.— Distribución geográfica y ensayo de la ecológica de los Cóccidos en España. RAMÓN MARGALEF.— Distribución de los crustáceos en las aguas continentales españoles. Grado de asociación entre las especies en relación con factores ecológicos e históricos. D. SELGA.— Interés biogeográfico de Proctostephanus (Collembola) del bosque esclerófilo mediterráneo. JOSÉ A. VALVERDE.— Las aves esteparias de la Península Ibérica. ORIOL DE BOLÓS.— Grupos corológicos de la flora balear. G. COLOM. — Sobre algunas especies reliquias de las Baleares. FRANCISCO ESPAÑOL.— La evolución de la fauna colepterológica en las cavidades subterráneas ibériques. C. F. SACCHI et R. NOS.— Qulques distributions intéresantes des Mollusques terrestres ibériques. JULIO ÁLVAREZ SÁNCHEZ.— Carácter residual de las biocenosis no costeras de Euparypha pisana Müll. y estudio especial de la del Mar de Ontígola, en Aranjuez. G. COLOM.— El medio y la vida en las Baleares. Mmes. V. ALLORGE et S. JOVET-AST. — La distribution des Marchantiales dans la Péninsule Ibérique et au maroc. C. F. SACCHI.— Contributo alla conoscenza dei popolamenti nelle piccole isole mediterranee. VIII. Dati microsistemarici di polmonati terrestri e considerazioni biogeografiche sulle Baleari orientali. DIMAS FERNÁNDEZ-GALIANO.— Sobre la extinción del encebro o asno salvaje en los Montes Universales. S. V. PERIS. — Análisis biográfico de la fauna de Syrphidae de la Península Ibérica. S. V. PERIS. — Algunos tipos de distribución en e lMediterráneo occidental. EUGENIO ORTIZ. — E lvalor taxonómico de las llamadas razas cromosómicas de Grylotalpa gryllotalpa (L.).[Tomo 28] RAMÓN MARGALEF.— Materiales para el estudio de las comunidades bióticas de las aguas dulces y salobres, principalmente del NE. de España. RICARDO ZARIQUIEY ÁLVAREZ.— Sobre el Gén. Munida Leach 1820. Rectificación. FRANCISCO ESPAÑOL. — Colópteros de la Sierra de la Demanda. EUGENIO ORTIZ. — Distribución geográfica de los diaptómidos de la Península Ibérica. A. BADRINAS. — Micro-determinación de Zn en material vegetal mediante ácido etilen-diamini-tetracético e indicador fluorescente. 1.ª parte: Método. A. BADRINAS y J. F. AGUILÁ.— El revelado cromatográfico con indicador fluorescente de ácidos no volátiles monodi- y tricarboxílicos. M. CRUSAFONT PAIRÓ y J. TRUYOLS SANTONJA.— Ensayo sobre el establecimiento de una nueva fórmula de semejanza faunística. J. F. AGUILÁ SANCHO.— El empleo de la hidrazida maleica en la conservación de la variedad de cebolla Roja de exportación. M. MONTSERRAT UBACH TRULLÁS.— Estudio comparativo de la acción de los ácidos 2,4-diclorofenoxiacético y 2,4,5- triclorofenoxiacético sobre el crecimiento de las raíces de Cynard cardunculus L..Peer reviewe