Twenty-First Century Adaptations of Early Twentieth Century American Protest Literature

Twenty-First Century Adaptations of Early Twentieth Century American Protest Literature examines the resurgence of didactic political literature in the United States during the 21st century, specifically adaptations of early 20th century American leftist protest works by authors such as Upton Sinclair, Jack London, and Richard Wright. While the most political aspects of these writers’ fiction are often either criticized as too politically overt – such as Sinclair’s The Jungle and Wright’s Native Son – or forgotten in favor of an author’s perceived literary merit – London’s The Iron Heel in comparison to his other works like Call of the Wild – this project argues that contemporary adaptations of such didactic political works show an effort to accomplish previously unmet political goals and ideals. In effect, these contemporary didactic adaptations seek to recognize continued political failures in the United States because political reforms written about 100 years earlier remain unaddressed; additionally, these works push toward constant adaptation in the new century as a recognition of inequalities specific to a 21st century American citizenry. A previous so-called narrative of failure is adapted instead to a newly revitalized narrative, and a rejection of primarily faithful adaptations alone invites complex interrogation about the influences of changeable political stories

Retinopathy Screening: Assessing Knowledge & Educating Diabetic Patients in Caledonia County, Vermont

Diabetic retinopathy is the most common cause of severe vision loss in US adults. It is estimated that less than 50% of patients with diabetes consistently receive annual eye exams. Diabetic patients in rural communities may face additional barriers towards receiving recommended eye care as these communities generally have lower incomes, lower insurance rates and older populations. This project sought to educate diabetic patients about eye disease in a rural Vermont primary care practice using an active learning modality.https://scholarworks.uvm.edu/fmclerk/1580/thumbnail.jp

An Introduction to Pediatric Ophthalmology

Pediatric ophthalmology can feel like a completely different world compared to its adult counterpart. Children can sometimes be extremely challenging to examine and pediatric ophthalmologists examine a wide variety of age groups, including the non-verbal infant, the animated toddler, the adolescent, and the nonverbal adult. Careful exams are important at each stage of development because visual development is most critical in the first decade of life. Each patient group requires a distinctive expertise to perform an effective eye exam. This review gives a brief introduction to some topics central to pediatric ophthalmology, including common clinical tests, common pathology, and some “can’t miss” diagnoses

Ultrafast Dynamics of Carrier Multiplication in Quantum Dots

A quantum-kinetic approach to the ultrafast dynamics of carrier multiplication in semiconductor quantum dots is presented. We investigate the underlying dynamics in the electronic subband occupations and the time-resolved optical emission spectrum, focusing on the interplay between the light-matter and the Coulomb interaction. We find a transition between qualitatively differing behaviors of carrier multiplication, which is controlled by the ratio of the interaction induced time scale and the pulse duration of the exciting light pulse. On short time scales, i.e., before intra-band relaxation, this opens the possibility of detecting carrier multiplication without refering to measurements of (multi-)exciton lifetimes.Comment: 12 pages, 7 figures, submitte

Stem cells and fluid flow drive cyst formation in an invertebrate excretory organ.

Cystic kidney diseases (CKDs) affect millions of people worldwide. The defining pathological features are fluid-filled cysts developing from nephric tubules due to defective flow sensing, cell proliferation and differentiation. The underlying molecular mechanisms, however, remain poorly understood, and the derived excretory systems of established invertebrate models (Caenorhabditis elegans and Drosophila melanogaster) are unsuitable to model CKDs. Systematic structure/function comparisons revealed that the combination of ultrafiltration and flow-associated filtrate modification that is central to CKD etiology is remarkably conserved between the planarian excretory system and the vertebrate nephron. Consistently, both RNA-mediated genetic interference (RNAi) of planarian orthologues of human CKD genes and inhibition of tubule flow led to tubular cystogenesis that share many features with vertebrate CKDs, suggesting deep mechanistic conservation. Our results demonstrate a common evolutionary origin of animal excretory systems and establish planarians as a novel and experimentally accessible invertebrate model for the study of human kidney pathologies

Auscultation and Oscillometry Result in Different Blood Pressure Readings When Using Visual Display on an iOS Operated Device

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Phase II Clinical Trial of GM-CSF Treatment in Patients with Hormone-Refractory or Hormone-Naïve Adenocarcinoma of the Prostate

The objective of this Phase II clinical trial was to determine the effects of chronic GM-CSF dosing on PSA levels in men with hormone-refractory or hormone-naïve prostate cancer. Six hormone-refractory and 10 hormone-naïve patients were recruited from an institutional practice and were treated with 250 and 125 μg/m2 of GM-CSF, respectively, 3 times per week for continuous 12-week treatment cycles until evidence of disease progression, as indicated by 2 consecutive rising PSA levels. PSA levels were measured every 6 weeks. Of the 6 hormone-refractory patients, 2 were classified with progressive disease after 4 months and 1 after 1.75 months. The best PSA responses for the remaining 3 patients were 3%, 12%, and 32% declines which lasted from 1.75 to 8.5 months. Of the 10 hormone-naïve patients, 2 were classified with progressive disease after 3 and 12 months, and 1 patient met the criteria for stable disease after 7.75 months. The best PSA response for the remaining 7 patients ranged from 7% to 42% declines which lasted from 0.5 to 10 months. These results indicate that further study of GM-CSF administration is not warranted for hormone-refractory patients but is recommended for hormone-naïve patients using a chronic dosing regimen