Characteristics of Predation and Losses in the New York Sheep Industry

A questionnaire survey was used in 1985 to obtain data on predation and losses from New York sheep growers. Surveys were returned by 685 growers which was a 40% return rate. The average grower managed 160 acres, including 24 acres of pasture, kept 106 sheep and received 12% of the total family income from sheep farming. Sheep predation occurred on 44% of the farms and dogs were considered the most harmful predator by 88% of the growers with losses. Growers with sheep losses had significantly larger flocks, more acreage in pasture, larger farms and depended more heavily on sheep farming for income than growers without losses (p \u3c 0.05). Growers who had reduced their pasture acreage and were planning further reductions had significantly higher losses than growers whose acreage had remained constant or increased and were planning to add more pasture (p \u3c 0.001). Growers who had reduced their flock size also had significantly higher losses than those who had increased their flocks (p \u3c 0.05). Finally, individuals who would reduce or sell their flock if predation continued had significantly higher losses than growers who planned to use lethal predator control methods to combat future predation (p \u3e 0.05)

An Evaluation of the Cost and Effectiveness of Repellent Applications in Protecting Fruit Orchards

A summer repellent spray program was devised and implemented on a total of 110 acres (9 orchard blocks) of 1- to 3-year-old semi-dwarf apple trees. Cooperating growers were supplied with repellent (Hinder or Clearepel) as required, to allow them to adhere to a flexible 3-to 6-application schedule from May through August. Spraying costs, including labor, equipment, and spray materials, were estimated based on data provided by each cooperating grower for each application completed

Podcasting: A Beginner’s Guide to Technology’s Latest Trend

This article provides a starting place for teachers wanting to dabble with the latest trend in technology—podcasting. The authors present a general overview of a tool that will most likely be part of the teaching vernacular, if not now, in the very near future. We offer a short tutorial on podcasting as well as perspectives on how teachers might incorporate podcasts into their curricula. We also summarize the value and limitations of podcasts, and perhaps most importantly, we include a resource guide to some of the more intriguing and useful podcasts currently available

ASSESSING DEER DAMAGE IN YOUNG FRUIT ORCHARDS

Evaluations of systematic damage assessments of 5, 10 and 20 percent of all apple trees in 12 orchards were compared. The 10% assessment technique was selected as the most accurate and efficient in estimating summer and fall damage. Analysis of several parameters of tree vigor found significant differences between browsed and unbrowsed trees for tree basal diameter and central leader diameter over 2 successive years. These subtle yet important differences in tree development were felt to severely limit the possibilities of relating browsing to growth and. later, yields. Methods and considerations for making control decisions on a per acre basis are discussed

Elements in biological AMS

AMS (Accelerator Mass Spectrometry) provides high detection sensitivity for isotopes whose half-lives are between 10 years and 100 million years. {sup 14}C is the most developed of such isotopes and is used in tracing natural and anthropogenic organic compounds in the Earth`s biosphere. Thirty-three elements in the main periodic table and 17 lanthanides or actinides have long lived isotopes, providing potential tracers for research in elemental biochemistry. Overlap of biologically interesting heavy elements and possible AMS tracers is discussed

Protocadherin 19 (PCDH19) interacts with paraspeckle protein NONO to co-regulate gene expression with estrogen receptor alpha (ERalpha)

De novo and inherited mutations of X-chromosome cell adhesion molecule protocadherin 19 (PCDH19) cause frequent, highly variable epilepsy, autism, cognitive decline and behavioural problems syndrome. Intriguingly, hemizygous null males are not affected while heterozygous females are, contradicting established X-chromosome inheritance. The disease mechanism is not known. Cellular mosaicism is the likely driver. We have identified p54nrb/NONO, a multifunctional nuclear paraspeckle protein with known roles in nuclear hormone receptor gene regulation, as a PCDH19 protein interacting partner. Using breast cancer cells we show that PCDH19-NONO complex is a positive co-regulator of ERα-mediated gene expression. Expression of mutant PCDH19 affects at least a subset of known ERα-regulated genes. These data are consistent with our findings that genes regulated by nuclear hormone receptors and those involved in the metabolism of neurosteroids in particular are dysregulated in PCDH19-epilepsy girls and affected mosaic males. Overall we define and characterize a novel mechanism of gene regulation driven by PCDH19, which is mediated by paraspeckle constituent NONO and is ERα-dependent. This PCDH19-NONO-ERα axis is of relevance not only to PCDH19-epilepsy and its comorbidities but likely also to ERα and generally nuclear hormone receptor-associated cancers.Duyen H. Pham, Chuan C. Tan, Claire C. Homan, Kristy L. Kolc, Mark A. Corbett, Dale McAninch, Archa H. Fox, Paul Q. Thomas, Raman Kumar Jozef Gec

Can the magnetic moment contribution explain the A_y puzzle?

We evaluate the full one-photon-exchange Born amplitude for $Nd$ scattering. We include the contributions due to the magnetic moment of the proton or neutron, and the magnetic moment and quadrupole moment of the deuteron. It is found that the inclusion of the magnetic-moment interaction in the theoretical description of the $Nd$ scattering observables cannot resolve the long-standing $A_y$ puzzle.Comment: 7 pages, 2 Postscript figures; to appear in Phys.Rev.

Knockout of the epilepsy gene Depdc5 in mice causes severe embryonic dysmorphology with hyperactivity of mTORC1 signalling

Published online: 03 October 2017DEPDC5 mutations have recently been shown to cause epilepsy in humans. Evidence from in vitro studies has implicated DEPDC5 as a negative regulator of mTORC1 during amino acid insufficiency as part of the GATOR1 complex. To investigate the role of DEPDC5 in vivo we generated a null mouse model using targeted CRISPR mutagenesis. Depdc5 homozygotes display severe phenotypic defects between 12.5-15.5 dpc, including hypotrophy, anaemia, oedema, and cranial dysmorphology as well as blood and lymphatic vascular defects. mTORC1 hyperactivity was observed in the brain of knockout embryos and in fibroblasts and neurospheres isolated from knockout embryos and cultured in nutrient deprived conditions. Heterozygous mice appeared to be normal and we found no evidence of increased susceptibility to seizures or tumorigenesis. Together, these data support mTORC1 hyperactivation as the likely pathogenic mechanism that underpins DEPDC5 loss of function in humans and highlights the potential utility of mTORC1 inhibitors in the treatment of DEPDC5-associated epilepsy.James Hughes, Ruby Dawson, Melinda Tea, Dale McAninch, Sandra Piltz, Dominique Jackson, Laura Stewart, Michael G. Ricos, Leanne M. Dibbens, Natasha L. Harvey and Paul Thoma

The AyA_y Puzzle and the Nuclear Force

The nucleon-deuteron analyzing power $A_y$ in elastic nucleon-deuteron scattering poses a longstanding puzzle. At energies $E_{lab}$ below approximately 30 MeV $A_y$ cannot be described by any realistic NN force. The inclusion of existing three-nucleon forces does not improve the situation. Because of recent questions about the $^3P_J$ NN phases, we examine whether reasonable changes in the NN force can resolve the puzzle. In order to do this we investigate the effect on the $^3P_J$ waves produced by changes in different parts of the potential (viz., the central force, tensor force, etc.), as well as on the 2-body observables and on $A_y$. We find that it is not possible with reasonable changes in the NN potential to increase the 3-body $A_y$ and at the same time to keep the 2-body observables unchanged. We therefore conclude that the $A_y$ puzzle is likely to be solved by new three-nucleon forces, such as those of spin-orbit type, which have not yet been taken into account.Comment: 35 pages in REVTeX, 1 figure in postscript and 3 figures in PiCTe