305 research outputs found

    Glueball plus Pion Production in Photon-Photon Collisions.

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    We here compute the reaction γ  γG  π0 \gamma \; \gamma \rightarrow G \; \pi^{0} for various glueball candidates G G and their assumed quantum states, using a non-relativistic gluon bound-state model for the glueball.Comment: To appear in Zeit. fur Phys. C; Plain Latex file, 16 pages; 5 figures appended as a uuencoded postscript file

    Glueball Production in Peripheral Heavy-Ion Collisions

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    The method of equivalent quanta is applied both to photon-photon and, by analogy, to double pomeron exchange in heavy-ion collisions. This Weizs\"acker-Williams approach is used to calculate production cross sections for the glueball candidate fJ(1710)f_J(1710) meson via photon-photon and pomeron-pomeron fusion in peripheral heavy-ion collisions at both RHIC and LHC energies. The impact-parameter dependence for total and elastic cross sections are presented, and are compared to results for proton-proton collisions.Comment: 15 pages, 6 figure

    An ultra-thin diamond membrane as a transmission particle detector and vacuum window for external microbeams

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    Several applications of external microbeam techniques demand a very accurate and controlled dose delivery. To satisfy these requirements when post-sample ion detection is not feasible, we constructed a transmission single-ion detector based on an ultra-thin diamond membrane. The negligible intrinsic noise provides an excellent signal-to-noise ratio and enables a hit-detection efficiency of close to 100%, even for energetic protons, while the small thickness of the membrane limits beam spreading. Moreover, because of the superb mechanical stiffness of diamond, this membrane can simultaneously serve as a vacuum window and allow the extraction of an ion microbeam into the atmosphere

    Outline of Synthesis of Cognitive and Socio-cultural Foundations of Scientific Knowledge Evolution in Research Programs of Western Philosophy of Science

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    The article analyses the development of cognitive sociology of science, in the object field of which connection of cognitive and social structures of science is traced. The role of context in scientific knowledge formation is defined. It is stated that the basis for development of research program of cognitive sociology of science appeared to be reconsideration of the standard concept of science as a complex of gnoseological, epistemological and methodological interpretations of nature and morphology of the produced scientific knowledge, methods for its explanation and scientificity ideals. The difference between "strong" and «weak» varieties of scientific knowledge evolution, developed in western philosophy of science, is considered. "Social studies of science" are reviewed as a form of social constructivism and relativism, exhibiting their specific nature in macro-analytical and micro- analytical strategies of scientific knowledge evolution analysis. The thesis that multidimensionality of science cannot be adequately interpreted focusing only on conceptual history of science is proved

    Multivalued SK-contractions with respect to b-generalized pseudodistances

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    A new class of multivalued non-self-mappings, called SK-contractions with respect to b-generalized pseudodistances, is introduced and used to investigate the existence of best proximity points by using an appropriate geometric property. Some new fixed point results in b-metric spaces are also obtained. Examples are given to support the usability of our main result

    Determination of the antimutagenicity of an aqueous extract of Rhizophora mangle L. (Rhizophoraceae), using in vivo and in vitro test systems

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    An aqueous extract of Rhizophora mangle L. bark is used as raw material in pottery making in the State of Espirito Santo, Brazil. This extract presents large quantities of tannins, compounds possessing antioxidant properties. Tannin antioxidant activity, as a plant chemical defense mechanism in the process of stabilizing free radicals, has been an incentive to studies on anti-mutagenicity. The present work aimed to evaluate possible antimutagenic activity of a R. mangle aqueous extract, using the Allium cepa test-system and micronuclear (MN) assay with blockage of cytokinesis in Chinese hamster ovary cells (CHO-K1). The Allium cepa test-system indicated antimutagenic activity against the damage induced by the mutagenic agent methyl methanesulfonate. A reduction in both MN cell frequency and chromosome breaks occurred in both the pre and post-treatment protocols. The MN testing of CHO-K1 cells revealed anti-mutagenic activity of the R. mangle extract against methyl methanesulfonate and doxorubicin in pre, simultaneous and post-treatment protocols. These results suggest the presence of phyto-constituents in the extract presenting demutagenic and bio-antimutagenic activities. Since the chemical constitution of Rhizophora mangle species presents elevated tannin content, it is highly probable that these compounds are the antimutagenic promoters themselves

    Diagnosis and outcome of acute respiratory failure in immunocompromised patients after bronchoscopy

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    Objective: We wished to explore the use, diagnostic capability and outcomes of bronchoscopy added to noninvasive testing in immunocompromised patients. In this setting, an inability to identify the cause of acute hypoxaemic respiratory failure is associated with worse outcome. Every effort should be made to obtain a diagnosis, either with noninvasive testing alone or combined with bronchoscopy. However, our understanding of the risks and benefits of bronchoscopy remains uncertain. Patients and methods: This was a pre-planned secondary analysis of Efraim, a prospective, multinational, observational study of 1611 immunocompromised patients with acute respiratory failure admitted to the intensive care unit (ICU). We compared patients with noninvasive testing only to those who had also received bronchoscopy by bivariate analysis and after propensity score matching. Results: Bronchoscopy was performed in 618 (39%) patients who were more likely to have haematological malignancy and a higher severity of illness score. Bronchoscopy alone achieved a diagnosis in 165 patients (27% adjusted diagnostic yield). Bronchoscopy resulted in a management change in 236 patients (38% therapeutic yield). Bronchoscopy was associated with worsening of respiratory status in 69 (11%) patients. Bronchoscopy was associated with higher ICU (40% versus 28%; p<0.0001) and hospital mortality (49% versus 41%; p=0.003). The overall rate of undiagnosed causes was 13%. After propensity score matching, bronchoscopy remained associated with increased risk of hospital mortality (OR 1.41, 95% CI 1.08-1.81). Conclusions: Bronchoscopy was associated with improved diagnosis and changes in management, but also increased hospital mortality. Balancing risk and benefit in individualised cases should be investigated further

    Early insights from statistical and mathematical modeling of key epidemiologic parameters of COVID-19

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    We report key epidemiologic parameter estimates for coronavirus disease identified in peer-reviewed publications, preprint articles, and online reports. Range estimates for incubation period were 1.8–6.9 days, serial interval 4.0–7.5 days, and doubling time 2.3–7.4 days. The effective reproductive number varied widely, with reductions attributable to interventions. Case burden and infection fatality ratios increased with patient age. Implementation of combined interventions could reduce cases and delay epidemic peak up to 1 month. These parameters for transmission, disease severity, and intervention effectiveness are critical for guiding policy decisions. Estimates will likely change as new information becomes available
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