Partial Evaluation for Java Malware Detection

The fact that Java is platform independent gives hackers the opportunity to write exploits that can target users on any platform, which has a JVM implementation. Metasploit is a well-known source of Java exploits and to circumvent detection by Anti Virus (AV) software, obfuscation techniques are routinely applied to make an exploit more difficult to recognise. Popular obfuscation techniques for Java include string obfuscation and applying reflection to hide method calls; two techniques that can either be used together or independently. This paper shows how to apply partial evaluation to remove these obfuscations and thereby improve AV matching. The paper presents a partial evaluator for Jimple, which is a typed three-address code suitable for optimisation and program analysis, and also demonstrates how the residual Jimple code, when transformed back into Java, improves the detection rates of a number of commercial AV products

Donor-derived infections: The Swiss perspective.

While Switzerland has not yet established a systematic approach, the small size of the country and the intensive collaboration between the transplant infectious disease teams facilitate a rapid communication once a donor-derived infection is suspected. Critical information regarding donor infections is shared rapidly, and appropriate measures are discussed. The long-term observational Swiss Transplant Cohort Study, which includes >92% of all solid organ recipients collects all relevant infectious disease episodes and facilitates detection of patterns of potential donor-derived infection

Donor‐derived infections: The Swiss perspective

While Switzerland has not yet established a systematic approach, the small size of the country and the intensive collaboration between the transplant infectious disease teams facilitate a rapid communication once a donor‐derived infection is suspected. Critical information regarding donor infections is shared rapidly, and appropriate measures are discussed. The long‐term observational Swiss Transplant Cohort Study, which includes >92% of all solid organ recipients collects all relevant infectious disease episodes and facilitates detection of patterns of potential donor‐derived infection

Rheagogies: modelling non-trophic effects in food webs

In a food web, nutrients flow via trophic links. For this reason, trophic interactions have a fundamental character due to the principle of mass conservation. To further comply with this principle, we consider a food web model that includes nutrient cycling. Non-trophic effects amongst species of the food web are modelled as interaction modifications, i.e., a functional change in the trophic interaction between two species caused by a third species (a three-party interaction that we call ‘‘rheagogy’’).We also consider that the ecological communities modelled by the food webs result from an assembly process that involves colonisations and extinctions. We find that two distinct classes of ecological communities must be distinguished: (a) ‘‘superefficient’’ communities, in which almost all available nutrients are incorporated into the biomass and (b) ‘‘sub-efficient’’ ones, in which a large proportion of nutrients is not fixed by living organisms. We show that rheagogies (that model non-trophic interactions) are crucial: the larger the effects of rheagogies, the easier the construction of super-efficient communities. These communities are characterized by positive rheagogies, meaning that a certain proportion of mutualistic interactions is necessary. Systems with few or weak rheagogies are less likely to use available abiotic resources efficiently. Although richness (i.e., number of species) is also positively related to efficient nutrient use, its importance is much smaller than that of rheagogies

Gaspar data-centric framework

This paper presents the Gaspar data-centric framework to develop high performance parallel applications in Java. Our approach is based on data iterators and on the map pattern of computation. The framework provides an efficient data Application Programming Inter-face(API) that supports flexible data layout and data tiling. Data layout and tiling enable the improvement of data locality, which is essential to foster application scalability in modern multi-core systems. The paper presents the framework data-centric concepts and shows that the performance is comparable to pure Java code.(undefined)info:eu-repo/semantics/publishedVersio

Determinación de la demanda nutricional en Liatris callilepis

Resumen (Spanish, English)78 p.El cultivo de Liatris callilepis en Chile ha alcanzado gran importancia al ocupar el tercer lugar en cuanto a volumen de flores exportadas en la temporada 93-94. Se analizó la demanda de NPK de un cultivo de liatris iniciado en diciembre. Se realizaron tres tratamientos en un diseño completamente al azar con las siguientes dosis de N, P y K (g/m2); 0:0:0; 35:17:3,3; 70:34:6,6, respectivamente, con cuatro repeticiones por tratamiento en parcelas experimentales de 3, 45 m2 (30 muestras por parcela). Como fuente fertilizante se utilizó Urea, Superfosfato triple y Muriato de potasio. La dosis de N y K se parcializó y el P se aplicó en la plantación. Durante el cultivo se analizó la absorción de nutrientes y la acumulación de peso seco. No hubo diferencia en el rendimiento de peso seco y la calidad floral (largo de vara y relación espiga/vara). La calidad floral fue óptima con una mínima absorción de nutrientes (290 kg de N, 35 kg de P y 334 de K). Con la curva de crecimiento de liatris a través de sus estados fenológicos, se planteó una propuesta de fertilización, la cual reduce los costos de fertilización en relación a las normas de fertilización anteriormente utilizadas

Toward sharing brain images: Differentially private TOF-MRA images with segmentation labels using generative adversarial networks

Sharing labeled data is crucial to acquire large datasets for various Deep Learning applications. In medical imaging, this is often not feasible due to privacy regulations. Whereas anonymization would be a solution, standard techniques have been shown to be partially reversible. Here, synthetic data using a Generative Adversarial Network (GAN) with differential privacy guarantees could be a solution to ensure the patient's privacy while maintaining the predictive properties of the data. In this study, we implemented a Wasserstein GAN (WGAN) with and without differential privacy guarantees to generate privacy-preserving labeled Time-of-Flight Magnetic Resonance Angiography (TOF-MRA) image patches for brain vessel segmentation. The synthesized image-label pairs were used to train a U-net which was evaluated in terms of the segmentation performance on real patient images from two different datasets. Additionally, the Fréchet Inception Distance (FID) was calculated between the generated images and the real images to assess their similarity. During the evaluation using the U-Net and the FID, we explored the effect of different levels of privacy which was represented by the parameter ϵ. With stricter privacy guarantees, the segmentation performance and the similarity to the real patient images in terms of FID decreased. Our best segmentation model, trained on synthetic and private data, achieved a Dice Similarity Coefficient (DSC) of 0.75 for ϵ = 7.4 compared to 0.84 for ϵ = ∞ in a brain vessel segmentation paradigm (DSC of 0.69 and 0.88 on the second test set, respectively). We identified a threshold of ϵ <5 for which the performance (DSC <0.61) became unstable and not usable. Our synthesized labeled TOF-MRA images with strict privacy guarantees retained predictive properties necessary for segmenting the brain vessels. Although further research is warranted regarding generalizability to other imaging modalities and performance improvement, our results mark an encouraging first step for privacy-preserving data sharing in medical imaging

Distinct Clinical and Laboratory Patterns of Pneumocystis jirovecii Pneumonia in Renal Transplant Recipients.

Late post-transplant Pneumocystis jirovecii pneumonia (PcP) has been reported in many renal transplant recipients (RTRs) centers using universal prophylaxis. Specific features of PcP compared to other respiratory infections in the same population are not well reported. We analyzed clinical, laboratory, administrative and radiological data of all confirmed PcP cases between January 2009 and December 2014. To identify factors specifically associated with PcP, we compared clinical and laboratory data of RTRs with non-PcP. Over the study period, 36 cases of PcP were identified. Respiratory distress was more frequent in PcP compared to non-PcP (tachypnea: 59%, 20/34 vs. 25%, 13/53, p = 0.0014; dyspnea: 70%, 23/33 vs. 44%, 24/55, p = 0.0181). In contrast, fever was less frequent in PcP compared to non-PcP pneumonia (35%, 11/31 vs. 76%, 42/55, p = 0.0002). In both cohorts, total lymphocyte count and serum sodium decreased, whereas lactate dehydrogenase (LDH) increased at diagnosis. Serum calcium increased in PcP and decreased in non-PcP. In most PcP cases (58%, 21/36), no formal indication for restart of PcP prophylaxis could be identified. Potential transmission encounters, suggestive of interhuman transmission, were found in 14/36, 39% of patients. Interhuman transmission seems to contribute importantly to PcP among RTRs. Hypercalcemia, but not elevated LDH, was associated with PcP when compared to non-PcP

State of Emergency Medicine in Switzerland: a national profile of emergency departments in 2006

BACKGROUND: Emergency departments (EDs) are an essential component of any developed health care system. There is, however, no national description of EDs in Switzerland. Our objective was to establish the number and location of EDs, patient visits and flow, medical staff and organization, and capabilities in 2006, as a benchmark before emergency medicine became a subspecialty in Switzerland. METHODS: In 2007, we started to create an inventory of all hospital-based EDs with a preliminary list from the Swiss Society of Emergency and Rescue Medicine that was improved with input from ED physicians nationwide. EDs were eligible if they offered acute care 24 h per day, 7 days per week. Our goal was to have 2006 data from at least 80% of all EDs. The survey was initiated in 2007 and the 80% threshold reached in 2012. RESULTS: In 2006, Switzerland had a total of 138 hospital-based EDs. The number of ED visits was 1.475 million visits or 20 visits per 100 inhabitants. The median number of visits was 8,806 per year; 25% of EDs admitted 5,000 patients or less, 31% 5,001-10,000 patients, 26% 10,001-20,000 patients, and 17% &gt;20,000 patients per year. Crowding was reported by 84% of EDs with &gt;20,000 visits/year. Residents with limited experience provided care for 77% of visits. Imaging was not immediately available for all patients: standard X-ray within 15 min (70%), non-contrast head CT scan within 15 min (38%), and focused sonography for trauma (70%); 67% of EDs had an intensive care unit within the hospital, and 87% had an operating room always available. CONCLUSIONS: Swiss EDs were significant providers of health care in 2006. Crowding, physicians with limited experience, and the heterogeneity of emergency care capabilities were likely threats to the ubiquitous and consistent delivery of quality emergency care, particularly for time-sensitive conditions. Our survey establishes a benchmark to better understand future improvements in Swiss emergency care

Reusability of filtering facepiece respirators after decontamination through drying and germicidal UV irradiation.

During pandemics, such as the SARS-CoV-2, filtering facepiece respirators plays an essential role in protecting healthcare personnel. The recycling of respirators is possible in case of critical shortage, but it raises the question of the effectiveness of decontamination as well as the performance of the reused respirators. Disposable respirators were subjected to ultraviolet germicidal irradiation (UVGI) treatment at single or successive doses of 60 mJ/cm &lt;sup&gt;2&lt;/sup&gt; after a short drying cycle (30 min, 70°C). The germicidal efficacy of this treatment was tested by spiking respirators with two staphylococcal bacteriophages (vB_HSa_2002 and P66 phages). The respirator performance was investigated by the following parameters: particle penetration (NaCl aerosol, 10-300 nm), scanning electron microscopy (SEM), Fourier-transform infrared spectroscopy (FTIR), differential scanning calorimetry and mechanical tensile tests. No viable phage particles were recovered from any of the respirators after decontamination (log reduction in virus titre &gt;3), and no reduction in chemical or physical properties (SEM, particle penetrations &lt;5%-6%) were observed. Increasing the UVGI dose 10-fold led to chemical alterations of the respirator filtration media (FTIR) but did not affect the physical properties (particle penetration), which was unaltered even at 3000 mJ/cm &lt;sup&gt;2&lt;/sup&gt; (50 cycles). When respirators had been used by healthcare workers and undergone decontamination, they had particle penetration significantly greater than never donned respirators. This decontamination procedure is an attractive method for respirators in case of shortages during a SARS pandemic. A successful implementation requires a careful design and particle penetration performance control tests over the successive reuse cycles