Community Health Workers and Community Voices: Promoting Good Health

Documents how CHWs address the problems of health disparities, poor access to care, and the rising cost of health care. Examines challenges that exist in expanding current CHW programs, and policy options around finance, workforce, and delivery of care

Uji Efektivitas Pupuk Organonitrofos Dan Kombinasinya Dengan Pupuk Kimia Terhadap Pertumbuhan, Serapan Hara Dan Produksi Tanaman Jagung Manis (Zea Mays Saccharata ) Di Musim Tanam Ketiga Pada Tanah Ultisol Gedung Meneng

Organonitrofos fertilizer is organic fertilizer derived from cow manure enriched with rock phosphate and microbial activity involves fastening N and phosphate newly developed solvent. This study aimed to determine dose combination Organonitrofos fertilizers and inorganic fertilizers are most effective against the growth, nutrient uptake, and yield of sweet corn. This research was conducted in November 2012 until March 2013 in the Integrated Field Laboratory, University of Lampung using Random Design (RBD) consisting of 6 treatments with 3 groups. Treatment A (control), B (300 kg Urea ha-1, 200 kg of SP-36 ha-1, 100 kg of KCl ha-1), C (225 kg Urea ha-1, 150 kg SP-36 ha-1, 75 kg KCl ha-1, 1000 kg Organonitrofos ha-1), D (150 kg Urea ha-1, 100 kg of SP-36 ha-1, 50 kg of KCl ha-1, 1,500 kg Organonitrofos ha-1), E (Urea 75 kg ha-1, SP-36 50 kg ha-1, 25 kg ha-1 KCl, Organonitrofos 2000 kg ha-1), F (3,000 Organonitrofos kg ha-1). The results showed that treatment at a dose of 150 kg of urea ha-1, SP-36 100 kg ha-1, 50 kg ha-1 KCl, Organonitrofos 1500 kg ha-1 is able to increase the growth, production and sweet corn crop nutrient uptake. This treatment was also the most effective treatment of the total biomass of sweet corn plants based on calculations Relative Agronomic Effectivenes (RAE) that is equal to 108.573%. Economical test results showed that treatment at a dose of 300 kg of urea ha-1, SP-36 200 kg ha-1, 100 kg ha-1 KCl most economical compared to other treatments

Uji Efektifitas Pupuk Organonitrofos Dan Kombinasinya Dengan Pupuk Kimia Terhadap Pertumbuhan, Serapan Hara Dan Produksi Tanaman Kedelai (Glycine Max L. Merr) Pada Musim Tanam Ketiga

Pupuk Organonitrofos merupakan pupuk berbahan baku kotoran sapi, batuan fosfat, mikroorganisme pelarut fosfat (MPF) dan N-fikser yang baru dikembangkan di Provinsi Lampung. Penelitian ini bertujuan untuk mengetahui dosis terbaik dari kombinasi pupuk Organonitrofos dengan pupuk kimia dalam meningkatkan pertumbuhan, serapan hara dan produksi tanaman kedelai pada musim tanam ketiga, serta menguji efektivitas pupuk Organonitrofos dan kombinasinya dengan pupuk kimiasecara agronomi maupun secara ekonomi pada tanaman kedelai musim tanam ketiga. Penelitian dilaksanakan pada bulan Mei sampai Desember 2013 di Laboratorium Lapang Terpadu dan Laboratorium Ilmu Tanah Universitas Lampung. Pada penelitian ini terdapat 6 perlakuan dan 3 ulangan. Percobaan dilakukan dengan Rancangan Acak Kelompok (RAK). Hasil penelitian menunjukkan bahwa perlakuan kombinasi pupuk Organonitrofos dengan pupuk kimia 40 kg urea ha -1 , 50 kg SP-36 ha -1 , 50 kg KCl ha -1 , 2500 kg Organonitrofos ha -1 memberikan nilai tertinggi dibandingkan perlakuan kombinasi lainnya dalam hal bobotpolong, bobot biji dan serapan hara N, P dan K biji. Kombinasi pupuk Organonitrofos dengan pupuk kimia memberikan pengaruh terbaik terhadap bobot berangkasan, serapan hara N, P dan K tanaman dan produksi secara RAE (Relative Agronomic Effectiviness) pada perlakuan 20 kg urea ha -1 , 25 kg SP-36 ha -1 , 25 kg KCl ha -1 , 3000 kg Organonitrofos ha -

Synergistic Inhibiting Effect of Phytochemicals in Rheum palmatum on Tyrosinase Based on Metabolomics and Isobologram Analyses

Tyrosinase (TYR) plays a key role in the enzymatic reaction that is responsible for a range of unwanted discoloration effects, such as food browning and skin hyperpigmentation. TYR inhibitors could, therefore, be candidates for skin care products that aim to repair pigmentation problems. In this study, we used a metabolomics approach combined with the isobologram analysis to identify anti-TYR compounds within natural resources, and evaluate their possible synergism with each other. Rheum palmatum was determined to be a model plant for observing the effect, of which seven extracts with diverse phytochemicals were prepared by way of pressurized solvent extraction. Each Rheum palmatum extract (RPE) was profiled using nuclear magnetic resonance spectroscopy and its activity of tyrosinase inhibition was evaluated. According to the orthogonal partial least square analysis used to correlate phytochemicals in RPE with the corresponding activity, the goodness of fit of the model (R2 = 0.838) and its predictive ability (Q2 = 0.711) were high. Gallic acid and catechin were identified as the active compounds most relevant to the anti-TYR effect of RPE. Subsequently, the activity of gallic acid and catechin were evaluated individually, and when combined in various ratios by using isobologram analysis. The results showed that gallic acid and catechin in the molar ratios of 9:5 and 9:1 exhibited a synergistic inhibition on TYR, with a combination index lower than 0.77, suggesting that certain combinations of these compounds may prove effective for use in cosmetic, pharmaceutical, and food industries

Functional and morphological lumbar multifidus characteristics in subgroups with low back pain in primary care

Background: Since the contribution of the lumbar multifidus(LM) is not well understood in relation to nonspecific low back pain(LBP), this may limit physiotherapists in choosing the most appropriate treatment strategy. Objectives: This study aims to compare clinical characteristics, in terms of LM function and morphology, between subacute and chronic LBP patients from a large clinical practice cohort compared to healthy controls. Design: Multicenter case control study. Method: Subacute and chronic LBP patients and healthy controls between 18 and 65 years of age were included. Several clinical tests were performed: primary outcomes were the LM thickness from ultrasound measurements, trunk range of motion(ROM) from 3D kinematic tests, and median frequency and root mean square values of LM by electromyography measurements. The secondary outcomes Numeric Rating Scale for Pain(NRS) and the Oswestry Disability Index(ODI) were administered. Comparisons between groups were made with ANOVA, pvalues< 0.05, with Tukey’s HSD post-hoc test were considered significant. Results: A total of 161 participants were included, 50 healthy controls, 59 chronic LBP patients, and 52 subacute LBP patients. Trunk ROM and LM thickness were significantly larger in healthy controls compared to all LBP patients(p < 0.01). A lower LM thickness was found between subacute and chronic LBP patients although not significant(p = 0.11–0.97). All between-group comparisons showed no statistically significant differences in electromyography outcomes (p = 0.10–0.32). NRS showed no significant differences between LBP subgroups(p = 0.21). Chronic LBP patients showed a significant higher ODI score compared to subacute LBP patients(p = 0.03). Conclusions: Trunk ROM and LM thickness show differences between LBP patients and healthy controls

Colors Of Graphite On Silicon Dioxide

Monoatomic layers of graphite can be electrically contacted and used as building blocks for new promising devices. These experiment are today possible thanks to the fact that very thin graphite can be identified on a dielectric substrate using a simple optical microscope. We investigate the mechanism behind the strong visibility of graphite and we discuss the importance of the substrate and of the microcope objective used for the imaging.Comment: 4 pages, 4 figures, abstract reviewed&accepted for presentation at EP2DS-1

Single Nucleotide Polymorphism Typing of Bacillus anthracis from Sverdlovsk Tissue

A small number of conserved canonical single nucleotide polymorphisms (canSNP) that define major phylogenetic branches for Bacillus anthracis were used to place a Sverdlovsk patient’s B. anthracis genotype into 1 of 12 subgroups. Reconstruction of the pagA gene also showed a unique SNP that defines a new lineage for B. anthracis

Disruption of NBS1 gene leads to early embryonic lethality in homozygous null mice and induces specific cancer in heterozygous mice

Nijmegen breakage syndrome (NBS) is a rare autosomal recessive chromosome instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition, with cellular features similar to that of ataxia telangiectasia (AT). NBS results from mutations in the mammalian gene Nbs1 that codes for a 95-kDa protein called nibrin, NBS1, or p95. To establish an animal model for NBS, we attempted to generate NBS1 knockout mice. However, NBS1 gene knockouts were lethal at an early embryonic stage. NBS1 homozygous(-/-) blastocyst cells cultured in vitro showed retarded growth and subsequently underwent growth arrest within 5 days of culture. Apoptosis, assayed by TUNEL staining, was observed in NBSI homozygous(-/-) blastocyst cells cultured for four days. NBSI heterozygous(+/-) mice were normal, and exhibited no specific phenotype for at least one year. However, fibroblast cells from NBSI heterozygous(+/-) mice displayed an enhanced frequency of spontaneous transformation to anchorage-independent growth as compared to NBS1 wild-type(+/+) cells. Furthermore, heterozygous(+/-) mice exhibited a high incidence of hepatocellular carcinoma after one year compared to wild-type mice, even though no significant differences in the incidence of other tumors such as lung adenocarcinoma and lymphoma were observed. Taken together, these results strongly suggest that NBS1 heterozygosity and reduced NBSI expression induces formation of specific tumors in mice

AI-Driven Assessment of Students: Current Uses and Research Trends

During the last decade, the use of AIs is being incorporated into the educational field whether to support the analysis of human behavior in teachinglearning contexts, as didactic resource combined with other technologies or as a tool for the assessment of the students. This proposal presents a Systematic Literature Review and mapping study on the use of AIs for the assessment of students that aims to provide a general overview of the state of the art and identify the current areas of research by answering 6 research questions related with the evolution of the field, and the geographic and thematic distribution of the studies. As a result of the selection process this study identified 20 papers focused on the research topic in the repositories SCOPUS and Web of Science from an initial amount of 129. The analysis of the papers allowed the identification of three main thematic categories: assessment of student behaviors, assessment of student sentiments and assessment of student achievement as well as several gaps in the literature and future research lines addressed in the discussion