Large and Small Polaron Excitations in La2/3(Sr/Ca)1/3MnO3 Films

We present detailed optical measurements of the mid-infrared (MIR) excitations in thin films of La2/3Sr1/3MnO3 (LSMO) and La2/3Ca1/3MnO3 (LCMO) across the magnetic transition. The shape of the excitation at about 0.2 eV in both samples is analyzed in terms of polaron models. We propose to identify the MIR resonance in LSMO as the excitation of large polarons and that in LCMO as a small polaron excitation. A scaling behavior for the low-energy side of the polaronic MIR resonance in LSMO is established

Survey of the ULF wave Poynting vector near the Earth's magnetic equatorial plane

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/101878/1/pdfexplain.pdfhttp://deepblue.lib.umich.edu/bitstream/2027.42/101878/2/jgra50591.pdfhttp://deepblue.lib.umich.edu/bitstream/2027.42/101878/3/pdfexplain.tx

The development of RAPTA compounds for the treatment of tumors

© 2015 Elsevier B.V. Ruthenium(II)-arene RAPTA-type compounds have been extensively explored for their medicinal properties. Herein a comprehensive review of this class of compounds is provided. A discussion of the basic RAPTA structure is given together with the ways it has been modified to elucidate the key role of each part and to afford targeted derivatives. The various mechanistic studies conducted on RAPTA compounds are described and these are linked to the observed macroscopic biological properties. Ultimately, the review shows that certain RAPTA compounds display quite unique properties that point towards a clinical investigation

How a realistic magnetosphere alters the polarizations of surface, fast magnetosonic, and Alfvén waves

Funding: MOA holds a UKRI (STFC / EPSRC) Stephen Hawking Fellowship EP/T01735X/1. DJS was supported by STFC grant ST/S000364/1. MDH was supported by NASA grant 80NSSC19K0127. A.N.W. was partially funded by STFC grant ST/N000609/1.System-scale magnetohydrodynamic (MHD) waves within Earth?s magnetosphere are often understood theoretically using box models. While these have been highly instructive in understanding many fundamental features of the various wave modes present, they neglect the complexities of geospace such as the inhomogeneities and curvilinear geometries present. Here we show global MHD simulations of resonant waves impulsively-excited by a solar wind pressure pulse. Although many aspects of the surface, fast magnetosonic (cavity/waveguide), and Alfvén modes present agree with the box and axially symmetric dipole models, we find some predictions for large-scale waves are significantly altered in a realistic magnetosphere. The radial ordering of fast mode turning points and Alfvén resonant locations may be reversed even with monotonic wave speeds. Additional nodes along field lines that are not present in the displacement/velocity occur in both the perpendicular and compressional components of the magnetic field. Close to the magnetopause the perpendicular oscillations of the magnetic field have the opposite handedness to the velocity. Finally, widely-used detection techniques for standing waves, both across and along the field, can fail to identify their presence. We explain how all these features arise from the MHD equations when accounting for a non-uniform background field and propose modified methods which might be applied to spacecraft observations.Publisher PDFPeer reviewe

Polaronic excitations in CMR manganite films

In the colossal magnetoresistance manganites polarons have been proposed as the charge carrier state which localizes across the metal-insulator transition. The character of the polarons is still under debate. We present an assessment of measurements which identify polarons in the metallic state of La{2/3}Sr{1/3}MnO{3} (LSMO) and La{2/3}Ca{1/3}MnO{3} (LCMO) thin films. We focus on optical spectroscopy in these films which displays a pronounced resonance in the mid-infrared. The temperature dependent resonance has been previously assigned to polaron excitations. These polaronic resonances are qualitatively distinct in LSMO and LCMO and we discuss large and small polaron scenarios which have been proposed so far. There is evidence for a large polaron excitation in LSMO and small polarons in LCMO. These scenarios are examined with respect to further experimental probes, specifically charge carrier mobility (Hall-effect measurements) and high-temperature dc-resistivity.Comment: 16 pages, 10 figure

Effects of loudness and complex speech on spataial and temporal precision in Parkinson's Disease

The paper presents preliminary results of a speech motor control study of hypokinetic dysarthria in Parkinson's disease (PD). By means of EPG, the tongue contacts of two speakers with PD and two control speakers during the production of target words containing initial /t/ stops were analysed in normal and loud condition as well as in complex sentences. The preliminary results showed no effects of increasing loudness on duration and on the number of tongue contacts in speakers with PD. Furthermore, frication of the stop /p/ to [f] was found for one speaker in the acoustic analysis.casl[1] Alm, P. 2004. Stuttering and the basal ganglia circuits: A critical review of possible relations. JCD 37, 325-369. [2] Dromey, C. Ramig, L.O. 1998. Intentional changes in sound pressure level and rate: Their impacts on measures of respiration, phonation, and articulation. JSLHR 41, 1003-1018. [3] Dromey, C. 2000. Articulatory kinematic in patients with Parkinson disease using different speech treatment approaches. Journal of Medical Speech-Language Pathology 8, 155-161. [4] Kent, R. D., Weismer, G., Kent, J. F., Rosenbek, J. C. 1989. Toward phonetic intelligibility testing in dysarthria. JSHD 54, 482-99. [5] Kleinow, J., Smith, A., Ramig, L.O. 2001. Speech motor stability in idiopathic Parkinson's disease: effects of rate and loudness manipulations. JSLHR 44, 1041-1051. [6] McAuliffe, M. J., Ward, E.C., Murdoch, B.E. 2006. Speech production in Parkinson's disease: I. An electropalatographic investigation of tongue-palate contact patterns. Clinical Linguistics and Phonetics 20, 1- 18. [7] McAuliffe, M. J., Ward, E.C., Murdoch, B.E. 2006. Speech production in Parkinson's disease: II. Acoustic and electropalatographic investigation of sentence, word and segment durations. Clinical Linguistics and Phonetics 20, 19-33. [8] Mooshammer, C., Hoole, P., Geumann, A. (in press). Jaw and order. Language and Speech. [9] Schulman, R. 1989. Articulatory dynamics of loud and normal speech. J. Acoust. Soc. Am. 85, 295-312. [10] Stevens, K.N. 1989. On the quantal nature of speech. Journal of Phonetics 17, 3-45.pub53pu

Simultaneous traveling convection vortex events and Pc1 wave bursts at cusp latitudes observed in Arctic Canada and Svalbard

Traveling convection vortices (TCVs), which appear in ground magnetometer records at near‐cusp latitudes as solitary ~5 mHz pulses, are a signature of dynamical processes in the ion foreshock upstream of the Earth's bow shock that can stimulate transient compressions of the dayside magnetosphere. These compressions can also increase the growth rate of electromagnetic ion cyclotron (EMIC) waves, which appear in ground records at these same latitudes as bursts of Pc1 pulsations. In this study we have identified TCVs and simultaneous Pc1 burst events in two regions, Eastern Arctic Canada and Svalbard, using a combination of fluxgate magnetometers and search coil magnetometers in each region. By looking for the presence of TCVs and Pc1 bursts in two different sequences, we have found that the distribution of Pc1 bursts was more tightly clustered near local noon than that of TCV events, that neither TCVs nor Pc1 bursts were always associated with the other, and even when they occurred simultaneously their amplitudes showed little correlation. Magnetometer data from GOES‐12 were also used to characterize the strength of the magnetic compressions at geosynchronous orbit near the magnetic equator. Compressions > 2 nT at GOES‐12 occurred during 57% of the Canadian TCV events, but during ~85% of the simultaneous TCV/Pc1 burst events. There was again little evident correlation between TCV and GOES‐12 compression amplitudes. We have also documented unusually low EMIC wave activity during this deep solar minimum interval, and we attribute the low occurrence percentage of combined events in this study to this minimum. Key Points TCVs and Pc1 bursts often occur together in high‐latitude magnetometer data Pc1 events were more tightly clustered near local noon than TCV events Pc1 activity was unusually low during the solar activity minimum in 2008–2010.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/101826/1/jgra50604.pd

Household-level risk factors for water contamination and antimicrobial resistance in drinking water among households with children under 5 in rural San Marcos, Cajamarca, Peru

Household water contamination at point of use depends on human, animal and environmental factors embodying all aspects of a One Health approach. This study investigated the association between household factors, the presence of thermotolerant coliform, and the presence of antibiotic resistant bacteria in drinking water among 314 households with children under 5 in Cajamarca, Peru. This study analysed data from a baseline sampling of a randomized controlled trial, including household surveys covering household water management and factors such as household animals, as well as microbiological data from samples collected from drinking water. Data were analysed using generalized linear models. Drinking water samples collected from narrow-mouthed containers were less likely to be contaminated than samples collected from the faucet (OR = 0.55, p = 0.030) or wide mouthed containers. The presence of thermotolerant coliform was associated with owning farm birds, which increased the proportion of contamination from 42.2% to 59.1% (OR = 1.98, p = 0.017) and with animal waste observed in the kitchen area, which increased the prevalence of contamination from 51.4% to 65.6% (OR = 1.80, p = 0.024). Resistance to any antibiotic was higher among pig owners at 60%, relative to non-pig owners at 36.4% (OR = 1.97, p = 0.012) as well as households with free-roaming animals in the kitchen area at 59.6% compared to households without free-roaming animals at 39.7% (OR = 2.24, p = 0.035). Recent child antibiotic use increased the prevalence of trimethoprim-sulfamethoxazole resistance among E. coli isolates to 22.3% relative to 16.7% (OR = 3.00, p = 0.037). Overall, these findings suggest that water storage in a secure container to protect from in-home contamination is likely to be important in providing safe drinking water at point of use. In addition, transmission of thermotolerant coliform and AMR between domestic animals and human drinking water supplies is likely. Further research should explore transmission pathways and methods to support safe drinking water access in multi-species households

Coherent terabit communications with microresonator Kerr frequency combs

Optical frequency combs enable coherent data transmission on hundreds of wavelength channels and have the potential to revolutionize terabit communications. Generation of Kerr combs in nonlinear integrated microcavities represents a particularly promising option enabling line spacings of tens of GHz, compliant with wavelength-division multiplexing (WDM) grids. However, Kerr combs may exhibit strong phase noise and multiplet spectral lines, and this has made high-speed data transmission impossible up to now. Recent work has shown that systematic adjustment of pump conditions enables low phase-noise Kerr combs with singlet spectral lines. Here we demonstrate that Kerr combs are suited for coherent data transmission with advanced modulation formats that pose stringent requirements on the spectral purity of the optical source. In a first experiment, we encode a data stream of 392 Gbit/s on subsequent lines of a Kerr comb using quadrature phase shift keying (QPSK) and 16-state quadrature amplitude modulation (16QAM). A second experiment shows feedback-stabilization of a Kerr comb and transmission of a 1.44 Tbit/s data stream over a distance of up to 300 km. The results demonstrate that Kerr combs can meet the highly demanding requirements of multi-terabit/s coherent communications and thus offer a solution towards chip-scale terabit/s transceivers