80 research outputs found
Ten Simple Rules for Organizing an Unconference
This is an open access article distributed under the terms of the Creative Commons Attribution License.Peer Reviewe
Effects of hypertonic sodium chloride solution on the electrophysiologic alterations caused by bupivacaine in the dog heart
The plant LINC complex at the nuclear envelope
Significant advances in understanding the plant nuclear envelope have been made over the past few years; indeed, knowledge of the protein network at the nuclear envelope is rapidly growing. One such network, the linker of nucleoskeleton and cytoskeleton (LINC) complex, is known in animals to connect chromatin to the cytoskeleton through the nuclear envelope. The LINC complex is made of Sad1/Unc84 (SUN) and Klarsicht/Anc1/Syne1 homology (KASH) proteins which have been recently characterized in plants. SUN proteins are located within the inner nuclear membrane, while the KASH proteins are included into the outer nuclear membrane. SUN and KASH domains interact and bridge the two nuclear membranes. In Arabidopsis, KASH proteins also interact with the tryptophan-proline-proline (WPP) domain-interacting tail-anchored protein 1 (WIT1), associated with the nuclear pore complex and with myosin XI-i which directly interacts with the actin cytoskeleton. Although evidence for a plant LINC complex connecting the nucleus to the cytoskeleton is growing, its interaction with chromatin is still unknown, but knowledge gained from animal models strongly suggests its existence in plants. Possible functions of the plant LINC complex in cell division, nuclear shape, and chromatin organization are discussed
Development and validation of a health belief model based instrument for measuring factors influencing exercise behaviors to prevent osteoporosis in pre-menopausal women (HOPE)
Neighborhood characteristics and effects on physical activity in an urban minority community – application of Health Belief Model to findings from Creighton University Center for Promoting Health and Health Equity (CPHHE-REACH) initiative
Archaeal orthologs of Cdc45 and GINS form a stable complex that stimulates the helicase activity of MCM
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