883 research outputs found

    Constitutional Change in a Long-Depressed Community: A Case Study of Duluth, Minnesota

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    Duluth, a boom and bust city with a marginal economy, has a unique position outside the mainstream of American life that adds a different dimension lo the understanding of community politics. Settlement patterns have contributed to the development of separate business and labor subcommunities that are substantially alienated from and hostile to one another and have rarely been able to cooperate in any civic endeavor. Operating within the framework of a political system caricaturing that of Minnesota as a whole, the two subcommunities reversed the pattern of local concern found in other cities; labor became the progressive force in local matters while business played a highly conservative role. Since World War II, the decline of the city\u27s established economic base hos been completed. At the same time, the Democratic-Farmer- Labor Party has emerged as the dominant political party locally. Its leaders, in alliance with organized labor, have tried to do something about Duluth\u27s predicament. In J 956, they secured a major change in the city\u27s form of government that was designed to open the door to progress an other fronts. Ta do so, they forged an alliance with the business community that, at least temporarily, transcended the city\u27s normal cleavage. While the constitutional change was of little immediate importance, the effect of the alliance was ta convince community leaders on both sides that cooperation for civic improvement was possible, thus opening the door lo a series of government-aided developments that may hove for-reaching consequences for Duluth\u27s economic and social well-being

    Not Written in Stone

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    Using long-ignored constitutions of various Jewish organizations, this unique book uncovers the political history of Canadian Jewry since its beginning during the 1700s. Building on the premise that Jews, since time immemorial, have written down their values and ideologies, this study effectively demonstrates how these writings record the principles and values that motivated a community

    Pluralism, Federalism and Freedom

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    Wake Measurements and Loss Evaluation in a Controlled Diffusion Compressor Cascade

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    The article of record as published may be located at http://dx.doi.org/10.1115/1.2929120The results of two component laser-Doppler velocimeter (LDV) surveys made in the near wake (to one fifth chord) of a controlled diffusion (CD) compressor blade in a large-scale cascade wind tunnel are reported. The measurements were made at three positive incidence angles from near design to angles thought to approach stall. Comparisons were made with calibrated pressure probe and hot-wire wake measurements and good agreement was found. The flow was found to be fully attached at the trailing edge at all incidence angles and the wake profiles were found to be highly skewed. Despite the precision obtained in the wake velocity profiles, the blade loss could not be evaluated accurately without measurements of the pressure field. The blade trailing edge surface pressures and velocity profiles were found to be consistent with downstream pressure probe measurements of loss, allowing conclusions to be drawn concerning the design of the trailing edge

    Quantum fluctuations around black hole horizons in Bose-Einstein condensates

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    We study several realistic configurations allowing to realize an acoustic horizon in the flow of a one dimensional Bose-Einstein condensate. In each case we give an analytical description of the flow pattern, of the spectrum of Hawking radiation and of the associated quantum fluctuations. Our calculations confirm that the non local correlations of the density fluctuations previously studied in a simplified model provide a clear signature of Hawking radiation also in realistic configurations. In addition we explain by direct computation how this non local signal relates to short range modifications of the density correlations

    Evaluating the effects of PIRAC nitrogen-diffusion treatments on the mechanical performance of Ti-6Al-4V alloy

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    The authors would like to thank the European Regional Development Fund (Malta) for research equipment funded through the application of the project “Developing an Interdisciplinary Material Testing and Rapid Prototyping R&D Facility (Ref. no. 012)”. The authors are also greatly indebted to MATERAþ/ERA-NET Plus for funding support for this research (Project ESM-1935).Powder Immersion Reaction Assisted Coating (PIRAC) is a relatively simple nitrogen diffusion based process which has been proposed as a technique capable of considerable improvements in the tribological performance of ceramics and metals alike; however, the necessary exposure of the substrate material to high temperatures for several hours may have an adverse effect on the bulk properties of materials such as titanium alloys. The effect of PIRAC treatments on the bulk metallography and mechanical properties of Ti–6Al–4V has been studied. Following PIRAC nitrogen-diffusion treatment, studies using X-ray diffraction and cross-sectional microscopy have shown evidence of the formation of a thin (1.4 mm) TiN/Ti2N layer, together with the presence of some Ti3Al intermetallic phase. Semi- logarithmic S–N plots show a deleterious effect after PIRAC treatment in terms of material cyclic fatigue strength, particularly at higher treatment temperatures. Samples processed at 800 1C for 4 h however exhibit better fatigue performance than others treated at lower temperatures for longer nitriding times. Fractographic inspection has shown that fatigue cracks originate at (or near) the surface for the untreated Ti-alloy and from the subsurface regions following diffusion treatment, owing to the build-up of compressive stresses in the latter, which hinder crack propagation.peer-reviewe

    Non-classical ProIL-1beta activation during mammary gland infection is pathogen-dependent but caspase-1 independent

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    Infection of the mammary gland with live bacteria elicits a pathogen-specific host inflammatory response. To study these host-pathogen interactions wild type mice, NF-kappaB reporter mice as well as caspase-1 and IL-1beta knockout mice were intramammarily challenged with Escherichia coli (E. coli) and Staphylococcus aureus (S. aureus). The murine mastitis model allowed to compare the kinetics of the induced cytokine protein profiles and their underlying pathways. In vivo and ex vivo imaging showed that E. coli rapidly induced NF-kappaB inflammatory signaling concomitant with high mammary levels of TNF-alpha, IL-1 alpha and MCP-1 as determined by multiplex analysis. In contrast, an equal number of S. aureus bacteria induced a low NF-kappaB activity concomitant with high mammary levels of the classical IL-1beta fragment. These quantitative and qualitative differences in local inflammatory mediators resulted in an earlier neutrophil influx and in a more extensive alveolar damage post-infection with E. coli compared to S. aureus. Western blot analysis revealed that the inactive proIL-1beta precursor was processed into pathogen-specific IL-1beta fragmentation patterns as confirmed with IL-1beta knockout animals. Additionally, caspase-1 knockout animals allowed to investigate whether IL-1beta maturation depended on the conventional inflammasome pathway. The lack of caspase-1 did not prevent extensive proIL-1beta fragmentation by either of S. aureus or E. coli. These non-classical IL-1beta patterns were likely caused by different proteases and suggest a sentinel function of IL-1beta during mammary gland infection. Thus, a key signaling nodule can be defined in the differential host innate immune defense upon E. coli versus S. aureus mammary gland infection, which is independent of caspase-1
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