7,536 research outputs found
Self-dual formulations of d=3 gravity theories in the path-integral framework
We study the connection, at the quantum level, between d=2+1 dimensional
self-dual models with actions of growing (from first to fourth) order,
governing the dynamics of helicity +2 (or -2) massive excitations. We obtain
identities between generating functionals of the different models using the
path-integral framework, this allowing to establish dual maps among relevant
vacuum expectation values. We check consistency of these v.e.v.'s with the
gauge invariance gained in each mapping.Comment: 26 pages. LaTeX. Minor changes. Published in Int. J Modern Phys. A;
http://www.worldscinet.com/ijmp
Effect of Contrast-Enhanced Echocardiograms on the Prognosis of Infective Endocarditis
Objective - Infective endocarditis (IE) is an infectious disease of the cardiac valves where bacteria colonize the valves; typically, via the formation of vegetations. Recent research has shown that the microbubbles in a contrast-enhanced ultrasound (CEUS) examination can move and dislodge bacterial vegetations in vitro. This study investigated whether CEUS resulted in faster resolution of IE in vivo by dislodging the vegetations.
Methods - This IRB approved retrospective study reviewed 36 patients who were diagnosed with IE via echocardiography. Data was sourced from patients within the Jefferson University Hospital’s Cardiology EMR system by searching for contrast and vegetation from January 1st, 2013 – January 1st, 2018. Fifteen patients were not given contrast, whereas 21 patients were given contrast via agitated saline (n=16) or an ultrasound contrast agent (n=5). All patients received an echocardiogram after blood cultures confirmed an infection, but before resolution of infection (defined by negative blood cultures). A student’s t-test was used for analyses.
Results - The study population was heterogeneous in terms of sex (67.5% male) and race (70% Caucasian, 25% African American, and 5% Asian), with an average age of 51±20 years, and an average BMI of 29.65±7.43 in the contrast group and 27.67±3.16 in the non-contrast group (p=0.37). Following ultrasound, no patients had documented stroke, pulmonary embolism, or systemic blood clot, which physicians could have attributed to a thrombus resulting from dislodging of bacterial vegetation. Overall, blood cultures did not clear faster in patients receiving CEUS compared to those undergoing standard echocardiography, (2.63±2.69 days vs. 1.34 ±1.11 days, p=0.09). CEUS also did not shorten the admission length in patients with IE, (16.9±7.7 days vs. 19.9±12.1 days; p=0.36).
Conclusion - Based on this limited sample size, patients who underwent CEUS did not have a different prognosis when compared to patients who received a non-contrast echocardiogram
Robust ab initio calculation of condensed matter: transparent convergence through semicardinal multiresolution analysis
We present the first wavelet-based all-electron density-functional
calculations to include gradient corrections and the first in a solid. Direct
comparison shows this approach to be unique in providing systematic
``transparent'' convergence, convergence with a priori prediction of errors, to
beyond chemical (millihartree) accuracy. The method is ideal for exploration of
materials under novel conditions where there is little experience with how
traditional methods perform and for the development and use of chemically
accurate density functionals, which demand reliable access to such precision.Comment: 4 pages, 3 figures, 4 tables. Submitted to Phys. Rev. Lett. (updated
to include GGA
Genetic ancestry of participants in the National Children's Study.
BackgroundThe National Children's Study (NCS) is a prospective epidemiological study in the USA tasked with identifying a nationally representative sample of 100,000 children, and following them from their gestation until they are 21 years of age. The objective of the study is to measure environmental and genetic influences on growth, development, and health. Determination of the ancestry of these NCS participants is important for assessing the diversity of study participants and for examining the effect of ancestry on various health outcomes.ResultsWe estimated the genetic ancestry of a convenience sample of 641 parents enrolled at the 7 original NCS Vanguard sites, by analyzing 30,000 markers on exome arrays, using the 1000 Genomes Project superpopulations as reference populations, and compared this with the measures of self-reported ethnicity and race. For 99% of the individuals, self-reported ethnicity and race agreed with the predicted superpopulation. NCS individuals self-reporting as Asian had genetic ancestry of either South Asian or East Asian groups, while those reporting as either Hispanic White or Hispanic Other had similar genetic ancestry. Of the 33 individuals who self-reported as Multiracial or Non-Hispanic Other, 33% matched the South Asian or East Asian groups, while these groups represented only 4.4% of the other reported categories.ConclusionsOur data suggest that self-reported ethnicity and race have some limitations in accurately capturing Hispanic and South Asian populations. Overall, however, our data indicate that despite the complexity of the US population, individuals know their ancestral origins, and that self-reported ethnicity and race is a reliable indicator of genetic ancestry
A non local unitary vector model in 3-D
We present a unified analysis of single excitation vector models in 3D. We
show that there is a family of first order master actions related by duality
transformations which interpolate between the different models. We use a
Hamiltonian (2+1) analysis to show the equivalence of the self-dual and
topologically massive models with a covariant non local model which propagates
also a single massive excitation. It is shown how the non local terms appears
naturally in the path integral framework.Comment: 13 pages, 1 figur
Comment on "Information management in DNA replication modeled by directional, stochastic chains with memory" [J. Chem. Phys. 145, 185103 (2016)]
Arias-Gonzalez, JR.; Aleja, D. (2020). Comment on "Information management in DNA replication modeled by directional, stochastic chains with memory" [J. Chem. Phys. 145, 185103 (2016)]. The Journal of Chemical Physics. 152(4):1-2. https://doi.org/10.1063/1.5140055S121524Arias-Gonzalez, J. R. (2016). Information management in DNA replication modeled by directional, stochastic chains with memory. The Journal of Chemical Physics, 145(18), 185103. doi:10.1063/1.4967335The Journal of Chemical Physics14518185103201
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