Alien Registration- Stout, J C. (Portland, Cumberland County)

https://digitalmaine.com/alien_docs/25575/thumbnail.jp

Automatic assembly design project 1968/9: report of technical survey committee

An Industrial survey has been carried out to determine the desired features of an automatic as machine. A questionnaire was circulated to industry and the results of the 38% response obtained were analysed and plotted. From these, conclusions were drawn as to the industrial requirements of an assembly machine

Winter Active Bumblebees (Bombus terrestris) Achieve High Foraging Rates in Urban Britain

Background: Foraging bumblebees are normally associated with spring and summer in northern Europe. However, there have been sightings of the bumblebee Bombus terrestris during the warmer winters in recent years in southern England. But what floral resources are they relying upon during winter and how much winter forage can they collect? Methodology/Principal Findings: To test if urban areas in the UK provide a rich foraging niche for bees we set up colonies of B. terrestris in the field during two late winter periods (2005/6 & 2006/7) in London, UK, and measured their foraging performance. Fully automatic radio-frequency identification (RFID) technology was used in 2006/7 to enable us to record the complete foraging activity of individually tagged bees. The number of bumblebees present during winter (October 2007 to March 2008) and the main plants they visited were also recorded during transect walks. Queens and workers were observed throughout the winter, suggesting a second generation of bee colonies active during the winter months. Mass flowering shrubs such as Mahonia spp. were identified as important food resources. The foraging experiments showed that bees active during the winter can attain nectar and pollen foraging rates that match, and even surpass, those recorded during summer. Conclusions/Significance: B. terrestris in the UK are now able to utilise a rich winter foraging resource in urban parks and gardens that might at present still be under-exploited, opening up the possibility of further changes in pollinato

Recombinant Filaggrin Is Internalized and Processed to Correct Filaggrin Deficiency

This study was designed to engineer a functional filaggrin (FLG) monomer linked to a cell-penetrating peptide (RMR) and to test the ability of this peptide to penetrate epidermal tissue as a therapeutic strategy for genetically determined atopic dermatitis (AD). A single repeat of the murine filaggrin gene (Flg) was covalently linked to a RMR motif and cloned into a bacterial expression system for protein production. Purified FLG+RMR (mFLG+RMR) was applied in vitro to HEK-293T cells and a reconstructed human epidermis (RHE) tissue model. Immunochemistry demonstrated RMR-dependent cellular uptake of FLG+RMR in a dose- and time-dependent manner in HEK cells. Immunohistochemical staining of the RHE model identified penetration of FLG+RMR to the stratum granulosum, the epidermal layer at which FLG deficiency is thought to be pathologically relevant. In vivo application of FLG+RMR to FLG-deficient flaky tail (ft/ft) mice skin demonstrated internalization and processing of recombinant FLG+RMR to restore the normal phenotype. These results suggest that topically applied RMR-linked FLG monomers are able to penetrate epidermal tissue, be internalized into the appropriate cell type, and be processed to a size similar to wild-type functional barrier peptides to restore necessary barrier function, and prove to be therapeutic for patients with AD

Comparing the Iowa and Soochow Gambling Tasks in Opiate Users

The Iowa Gambling Task (IGT) is in many respects the gold standard for demonstrating decision making in drug using groups. However, it is not clear how basic task properties such as the frequency and magnitude of rewards and losses affect choice behavior in drug users and even in healthy players. In this study, we used a variant of the IGT, the Soochow Gambling Task (SGT), to observe choice behavior in opiate users and healthy decision makers in a task where reward frequency is not confounded with the long-term outcome of each alternative. In both opiate users (n = 26) and healthy controls (n = 27), we show that reward frequency strongly influences choice behavior in the IGT and SGT. Neither group showed a consistent preference across tasks for alternatives with good long-term outcomes, but rather, subjects appeared to prefer alternatives that win most frequently. We interpret this as evidence to suggest that healthy players perform better than opiate users on the IGT because they are able to utilize gain–loss frequencies to guide their choice behavior on the task. This challenges the previous notion that poorer performance on the IGT in drug users is due to an inability to be guided by future consequences

Bostonia: The Boston University Alumni Magazine. Volume 29

Founded in 1900, Bostonia magazine is Boston University's main alumni publication, which covers alumni and student life, as well as university activities, events, and programs

PERCEIVED RISKS OF DEER-RELATED VEHICLE ACCIDENTS: INFLUENCE ON DEER POPULATION PREFERENCES OF THE RESIDENTS OF TOMPKINS COUNTY, NEW YORK

High populations of white-tailed deer (Odocoileus virginianus) in much of the eastern United States have increased the probability of deer-related vehicle accidents (DRVAs). These accidents are very costly in terms of vehicle repair and have the potential for serious physical injury to motorists. DRVAs are increasing rapidly in suburban areas, where deer may also cause other types of damage (i.e., to gardens or ornamental shrubs). In these suburban areas, wildlife professionals have limited deer management options. We hypothesized that the peoples\u27 perception of the potential risk posed by DRVAs interacts with the perceived benefits provided by deer, to influence their desired deer population level. We conducted a mail survey of 624 randomly selected Tompkins County, New York residents (68% response rate, n = 424), to explore this hypothesis

Effects of Sex and Hormonal Implant on Beef Carcass Characteristics and Palatability

A comparison of crossbred bulls, steers and heifers indicated that bulls have heavier carcasses, larger rib eyes and a more desirable yield grade. The USDA quality grade of the bulls was one-third of a grade lower than for the steers and heifers. The sensory and palatability characteristics showed no significant differences among axes. Implanted bulls as compared to non-implanted bulls showed more desirable taste panel scores for tenderness, juiciness and overall panel desirability