New membership determination and proper motions of NGC 1817. Parametric and non-parametric approach

We have calculated proper motions and re-evaluated the membership probabilities of 810 stars in the area of two NGC objects, NGC 1817 and NGC 1807. We have obtained absolute proper motions from 25 plates in the reference system of the Tycho-2 Catalogue. The plates have a maximum epoch difference of 81 years; and they were taken with the double astrograph at Zo-Se station of Shanghai Observatory, which has an aperture of 40 cm and a plate scale of 30 arcsec/mm. The average proper motion precision is 1.55 mas/yr. These proper motions are used to determine the membership probabilities of stars in the region, based on there being only one very extended physical cluster: NGC 1817. With that aim, we have applied and compared parametric and non-parametric approaches to cluster/field segregation. We have obtained a list of 169 probable member stars.Comment: 11 pages, 8 figures, A&A in pres

Clusterix 2.0: a virtual observatory tool to estimate cluster membership probability

Clusterix 2.0 is a web-based, Virtual Observatory compliant, interactive tool for the determination of membership probabilities in stellar clusters based on proper-motion data using a fully non-parametric method. In an area occupied by a cluster, the frequency function is made up of two contributions: cluster and field stars. The tool performs an empirical determination of the frequency functions from the vector point diagram without relying on any previous assumption about their profiles. Clusterix 2.0 allows us to search the appropriate spatial areas in an interactive way until an optimal separation of the two populations is obtained. Several parameters can be adjusted to make the calculation computationally feasible without interfering with the quality of the results. The system offers the possibility to query different catalogues, such as Gaia, or upload a user's own data. The results of the membership determination can be sent via Simple Application Messaging Protocol (SAMP) to Virtual Observatory (VO) tools such as Tool for OPerations on Catalogues And Tables (TOPCAT). We apply Clusterix 2.0 to several open clusters with different properties and environments to show the capabilities of the tool: an area of five degrees radius around NGC 2682 (M67), an old, well-known cluster; a young cluster NGC 2516 with a striking elongated structure extended up to four degrees; NGC 1750 and NGC 1758, a pair of partly overlapping clusters; the area of NGC 1817, where we confirm a little-known cluster, Juchert 23; and an area with many clusters, where we disentangle two overlapping clusters situated where only one was previously known: Ruprecht 26 and the new CLUSTERIX 1.With funding from the Spanish government through the "María de Maeztu Unit of Excellence" accreditation (MDM-2017-0737

EBV, HCMV, HHV6, and HHV7 Screening in Bone Marrow Samples from Children with Acute Lymphoblastic Leukemia

Acute lymphoblastic leukemia (ALL) is the most common cancer in childhood worldwide and Mexico has reported one of the highest incidence rates. An infectious etiology has been suggested and supported by epidemiological evidences; however, the identity of the involved agent(s) is not known. We considered that early transmitted lymphotropic herpes viruses were good candidates, since transforming mechanisms have been described for them and some are already associated with human cancers. In this study we interrogated the direct role of EBV, HCMV, HHV6, and HHV7 human herpes viruses in childhood ALL. Viral genomes were screened in 70 bone marrow samples from ALL patients through standard and a more sensitive nested PCR. Positive samples were detected only by nested PCR indicating a low level of infection. Our result argues that viral genomes were not present in all leukemic cells, and, hence, infection most likely was not part of the initial genetic lesions leading to ALL. The high statistical power of the study suggested that these agents are not involved in the genesis of ALL in Mexican children. Additional analysis showed that detected infections or coinfections were not associated with prognosis