1,099 research outputs found

    Health Impacts of New Deal for Young People

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    Physical mechanisms involved in grooved flat heat pipes: experimental and numerical analyses

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    International audienceAn experimental database, obtained with flat plate heat pipes (FPHP) with longitudinal grooves is presented. The capillary pressure measured by confocal microscopy and the temperature field in the wall are presented in various experimental conditions (vapour space thickness, filing ratio, heat transfer rate, tilt angle, fluid). Coupled hydrodynamic and thermal models are developed. Experimental results are compared to results of numerical models. Physical mechanisms involved in grooved heat pipes are discussed, including the boiling limit and the effect of the interfacial shear stress. Finally, recommendations for future experimental and theoretical research to increase the knowledge on FPHP are discussed

    Heritable and nutritional influences on bone mineral mass

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    Osteoporosis is the net result of the maximal amount of bone mineral mass achieved by the end of pubertal growth (peak bone mass) minus post-menopausal and elderly bone losses. Peak bone mineral mass is determined from early childhood by both heritable and environmental factors. Recent developments in the molecular epidemiology of osteoporosis have shown the interest, but also the limitations, of specific molecular markers, such as the vitamin D receptor gene polymorphisms Bsm 1 and Fok 1, to explain bone mineral density differences across the population. Importantly, however, interactions between VDR gene polymorphisms and environmental factors, particularly dietary calcium, have provided new insights into the complex determination of bone mineral mas

    Influence of the Presence of CO2 in the Feed of an Indirect Heating TSA Process for VOC Removal

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    International audienceThis work deals with an experimental study of an indirect temperature swing adsorption process for VOC removal from air or for gas purification. A 1 m long and 70 mm diameter column with an internal heat exchanger has been filled with Ambersorb 600 carbonaceous adsorbent. This column is equipped with sensors to measure temperature at several points inside the bed, as well as the inlet and outlet gas concentration, pressure, temperature and mass flow. In a first step, CO2 or ethane/ dry nitrogen mixtures were used to simulate a single VOC in air, with different concentrations (350 ppm, 1% and 10%). As a first results very effective gas purification was obtained and an advantage of this process is the high pollutant concentration during the regeneration phase. Experiments were performed with various ethane/CO2 mixtures. The influence of the presence of CO2 on the ethane concentration breakthrough curves and on the ethane concentration during regeneration is reported. The IAS theory was used, as a first approach, to predict the adsorbed pollutants amount. Relatively good prediction is obtained with a maximum error in the order of 10%. An energy balance study is reported as well

    Pubertal timing and body mass index gain from birth to maturity in relation with femoral neck BMD and distal tibia microstructure in healthy female subjects

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    Summary: Childhood body mass index (BMI) gain is linked to hip fracture risk in elderly. In healthy girls, menarcheal age is inversely related to BMI gain during childhood and to femoral neck areal bone mass density (aBMD) and distal tibia structural components at maturity. This study underscores the importance of pubertal timing in age-related fragility fracture risk. Introduction: Recent data point to a relationship between BMI change during childhood and hip fracture risk in later life. We hypothesized that BMI development is linked to variation in pubertal timing as assessed by menarcheal age (MENA) which in turn, is related to peak bone mass (PBM) and hip fracture risk in elderly. Methods: We studied in a 124 healthy female cohort the relationship between MENA and BMI from birth to maturity, and DXA-measured femoral neck (FN) aBMD at 20.4year. At this age, we also measured bone strength related microstructure components of distal tibia by HR-pQCT. Results: At 20.4 ± 0.6year, FN aBMD (mg/cm2), cortical thickness (μm), and trabecular density (mgHA/cm3) of distal tibia were inversely related to MENA (P = 0.023, 0.015, and 0.041, respectively) and positively to BMI changes from 1.0 to 12.4years (P = 0.031, 0.089, 0.016, respectively). Significant inverse (P < 0.022 to <0.001) correlations (R = −0.21 to -0.42) were found between MENA and BMI from 7.9 to 20.4years, but neither at birth nor at 1.0year. Linear regression indicated that MENA Z-score was inversely related to BMI changes not only from 1.0 to 12.4years (R = −0.35, P = 0.001), but also from 1.0 to 8.9years, (R = −0.24, P = 0.017), i.e., before pubertal maturation. Conclusion: BMI gain during childhood is associated with pubertal timing, which in turn, is correlated with several bone traits measured at PBM including FN aBMD, cortical thickness, and volumetric trabecular density of distal tibia. These data complement the reported relationship between childhood BMI gain and hip fracture risk in later lif

    Spacetime structure of the global vortex

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    We analyse the spacetime structure of the global vortex and its maximal analytic extension in an arbitrary number of spacetime dimensions. We find that the vortex compactifies space on the scale of the Hubble expansion of its worldvolume, in a manner reminiscent of that of the domain wall. We calculate the effective volume of this compactification and remark on its relevance to hierarchy resolution with extra dimensions. We also consider strongly gravitating vortices and derive bounds on the existence of a global vortex solution.Comment: 19 pages revtex, 2 figures, minor changes, references adde

    Pubertal timing and body mass index gain from birth to maturity in relation with femoral neck BMD and distal tibia microstructure in healthy female subjects

    Get PDF
    Childhood body mass index (BMI) gain is linked to hip fracture risk in elderly. In healthy girls, menarcheal age is inversely related to BMI gain during childhood and to femoral neck areal bone mass density (aBMD) and distal tibia structural components at maturity. This study underscores the importance of pubertal timing in age-related fragility fracture risk

    Asynchrony between the rates of standing height gain and bone mass accumulation during puberty

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    During puberty, the marked increases in both standing height and bone mass appear to be dissociated in time, the former occurring earlier than the latter. However, the age or pubertal stage at which this dissociation is maximal in girls as opposed to boys, and whether this dissociation is similar at all parts of the skeleton, are not clearly established. Standing height and bone mineral mass, as assessed by measuring areal bone mineral density (BMD), at the levels of the lumbar spine, femoral neck and midfemoral shaft, were measured in 98 females and 100 males between the ages of 9 and 19 years twice at a 1-year interval. In males, the greatest difference between height and BMD gains occurred in the 13-14 year age group and was more pronounced for the lumbar spine and femoral neck than for the midfemoral shaft. In females, the greatest difference was detectable at a younger age (11-12 year age group) and appeared to be of a lower magnitude than in males. In both genders, the maximal difference occurred during the period of peak height velocity, which corresponded to the pubertal stages P2-P3. Such a dissociation between the rates of statural growth and mineral mass accrual could define a state of relatively low bone mass and contribute to the higher incidence of fracture known to occur at the age and/or pubertal stage when this dissociation is maxima
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