VLT/MUSE view of the highly ionized outflow cones in the nearby starburst ESO338-IG04

The Ly$\alpha$ line is an important diagnostic for star formation at high redshift, but interpreting its flux and line profile is difficult because of the resonance nature of Ly$\alpha$. Trends between the escape of Ly$\alpha$ photons and dust and properties of the interstellar medium (ISM) have been found, but detailed comparisons between Ly$\alpha$ emission and the properties of the gas in local high-redshift analogs are vital for understanding the relation between Ly$\alpha$ emission and galaxy properties. For the first time, we can directly infer the properties of the ionized gas at the same location and similar spatial scales of the extended Ly$\alpha$ halo around ESO 338-IG04. We obtained VLT/MUSE integral field spectra. We used ionization parameter mapping of the [SII]/[OIII] line ratio and the kinematics of H$\alpha$ to study the ionization state and kinematics of the ISM of ESO338-IG04. The velocity map reveals two outflows. The entire central area of the galaxy is highly ionized by photons leaking from the HII regions around the youngest star clusters. Three highly ionized cones have been identified, of which one is associated with an outflow. We propose a scenario where the outflows are created by mechanical feedback of the older clusters, while the highly ionized gas is caused by the hard ionizing photons emitted by the youngest clusters. A comparison with the Ly$\alpha$ map shows that the (approximately bipolar) asymmetries observed in the Ly$\alpha$ emission are consistent with the base of the outflows detected in H$\alpha$. No clear correlation with the ionization cones is found. The mechanical and ionization feedback of star clusters significantly changes the state of the ISM by creating ionized cones and outflows. The comparison with Ly$\alpha$ suggests that especially the outflows could facilitate the escape of Ly$\alpha$ photons [Abridged].Comment: Accepted for publication in A&A Letters, 4 pages, 2 figure

MUSE Illuminates Channels for Lyman Continuum Escape in the Halo of SBS 0335-52E

We report on the discovery of ionised gas filaments in the circum-galactic halo of the extremely metal-poor compact starburst SBS 0335-052E in a 1.5h integration with the MUSE integral-field spectrograph. We detect these features in H${\alpha}$ and [OIII] emission down to surface-brightness levels of $5 \times 10^{-19}$erg s$^{-1}$cm$^{-2}$arcsec$^{-2}$. The filaments have projected diameters of 2.1 kpc and extend more than 9 kpc to the north and north-west from the main stellar body. We also detect extended nebular HeII $\lambda$4686 emission that brightens towards the north-west at the rim of a star-burst driven super-shell, suggestive of a locally enhanced UV radiation field due to shocks. We also present a velocity field of the ionised gas. The filaments appear to connect seamlessly in velocity space to the kinematical disturbances caused by the shell. Similar to high-$z$ star-forming galaxies, the ionised gas in this galaxy is dispersion dominated. We argue that the filaments were created via feedback from the starburst and that these ionised structures in the halo may act as escape channels for Lyman continuum radiation in this gas-rich system.Comment: Revised version after peer review. Accepted for publication in A&A letter

Super star cluster feedback driving ionization, shocks and outflows in the halo of the nearby starburst ESO 338-IG04

Stellar feedback strongly affects the interstellar medium (ISM) of galaxies. Stellar feedback in the first galaxies likely plays a major role in enabling the escape of LyC photons, which contribute to the re-ionization of the Universe. Nearby starburst galaxies serve as local analogues allowing for a spatially resolved assessment of the feedback processes in these galaxies. We characterize the feedback effects from the star clusters in the local high-redshift analogue ESO 338-IG04 on the ISM and compare the results with the properties of the most massive clusters. We use high quality VLT/MUSE optical integral field data to derive the physical properties of the ISM such as ionization, density, shocks, and perform new fitting of the spectral energy distributions of the brightest clusters in ESO 338-IG04 from HST imaging. ESO 338-IG04 has a large ionized halo which we detect to a distance of 9 kpc. We identify 4 Wolf-Rayet (WR) clusters based on the blue and red WR bump. We follow previously identified ionization cones and find that the ionization of the halo increases with distance. Analysis of the galaxy kinematics shows two complex outflows driven by the numerous young clusters in the galaxy. We find a ring of shocked emission traced by an enhanced [OI]/H$\alpha$ ratio surrounding the starburst and at the end of the outflow. Finally we detect nitrogen enriched gas associated with the outflow, likely caused by the WR stars in the massive star clusters. Photo-ionization dominates the central starburst and sets the ionization structure of the entire halo, resulting in a density bounded halo, facilitating the escape of LyC photons. Outside the central starburst, shocks triggered by an expanding super bubble become important. The shocks at the end of the outflow suggest interaction between the hot outflowing material and the more quiescent halo gas.Comment: Accepted for publication in Astronomy and Astrophysics, 22 pages, 15 figure

Expression of SCGB1C1 gene as a potential marker of susceptibility to upper respiratory tract infections in elite athletes : a pilot study

High levels of exercise in athletes result in temporary immunosuppression, which could increase the susceptibility to upper respiratory tract infections. Understanding of immunological mechanisms responsible for this phenomenon could enable optimization of training schemes for elite athletes and avoidance of infection-related episodes of absence during sports championships. The aim of this study was to detect genes that may be responsible for modulation of individual susceptibility to infections. The blood and saliva samples were collected from 10 healthy, medically examined kayakers (4 females and 6 males) aged 24.7 ± 2.3 years. All samples were taken in the morning, after overnight fasting, in a seated position. The ELISA method was used to determine the levels of secretory immunoglobulin A (sIgA) and interleukin 5 (IL-5). Whole genome expression in blood was assessed using microarrays. The study did not reveal any significant correlation between genome expression and sIgA concentration. However, low expression of a gene involved in protection against the common cold – secretoglobin 1C1 (SCGB1C1) – was detected in athletes with high IL-5 concentrations (corrected p=0.00065; fold change=3.17). Our results suggest that blood expression of the SCGB1C1 gene might be a marker of susceptibility to upper respiratory tract infections in athletes

MTRNR2L12 : a candidate blood marker of early Alzheimer's disease-like dementia in adults with Down Syndrome

Morphological abnormalities observed typically in the brains of adults with Down syndrome are identical with those present in patients with Alzheimer’s disease. However, only some adults with Down syndrome suffer from early dementia, whereas others remain unaffected. We aimed to identify the genomic background responsible for this observation. We performed cognitive assessment and genome expression analysis of blood mononuclear cells in seniors with Down syndrome. Unaffected elderly patients and younger patients with severe cognitive disability or cognitive deterioration differed significantly with regard to the MTRNR2L12 gene. Our findings suggest the potential value of this gene as a blood marker of early dementia in individuals with Down syndrome

Sequential star formation in IRAS 06084-0611 (GGD 12-15): From intermediate-mass to high-mass stars

Context. The formation and early evolution of high- and intermediate-mass stars towards the main sequence involves the interplay of stars in a clustered and highly complex environment. To obtain a full census of this interaction, the Formation and Early evolution of Massive Stars (FEMS) collaboration studies a well-selected sample of 10 high-mass star-forming regions. Aims. In this study we examine the stellar content of the high-mass star-forming region centered on IRAS 06084-0611 in the Monoceros R2 cloud. Methods. Using the near-infrared H- and K-band spectra from the VLT/SINFONI instrument on the ESO Very Large Telescope (VLT)and photometric near-infrared NTT/SOFI, 2MASS and Spitzer/IRAC data, we were able to determine the spectral types for the most luminous stars in the cluster. Results. Two very young and reddened massive stars have been detected by SINFONI: a massive Young Stellar Object (YSO) con- sistent with an early-B spectral type and a Herbig Be star. Furthermore, stars of spectral type G and K are detected while still in the Pre-Main Sequence (PMS) phase. We derive additional properties such as temperatures, extinctions, radii and masses. We present a Hertzsprung-Russell diagram and find most objects having intermediate masses between \sim1.5-2.5 M\odot. For these stars we derive a median cluster age of \sim4 Myr. Conclusions. Using Spitzer/IRAC data we confirm earlier studies that the younger class 0/I objects are centrally located while the class II objects are spread out over a larger area, with rough scale size radii of \sim0.5 pc and \sim1.25 pc respectively. Moreover, the presence of a massive YSO, an ultracompact H ii region and highly reddened objects in the center of the cluster suggest a much younger age of < 1 Myr. A possible scenario for this observation would be sequential star formation along the line of sight; from a cluster of intermediate-mass to high-mass stars.Comment: 14 pages, 10 figures, 2 tables. Astronomy and Astrophysic

On the contribution of ULXs to stellar feedback: an intermediate mass black hole candidate and the population of ULXs in the low-metallicity starburst galaxy ESO 338-4

X-ray radiation from accreting compact objects is an important part of stellar feedback. The metal-poor galaxy ESO 338-4 has experienced vigorous starburst during the last 40 Myr and contains some of the most massive super star clusters in the nearby Universe. Given its starburst age and its star-formation rate, ESO 338-4 is one of the most efficient nearby manufactures of neutron stars and black holes, hence providing an excellent laboratory for feedback studies. We compared X-ray images and spectra obtained by XMM-Newton and Chandra telescopes with integral field spectroscopic VLT MUSE observations in the optical to constrain the nature of strong X-ray emitters. X-ray observations uncover three ultraluminous X-ray sources (ULXs) in ESO 338-4. The brightest among them, ESO 338~X-1, has X-ray luminosity in excess of 10^{40} erg/s. We speculate that ESO 338-4 is powered by accretion on an intermediate-mass (~300Msun) black hole. We show that X-ray radiation from ULXs and hot superbubbles strongly contributes to HeII ionization and general stellar feedback in this template starburst galaxy.Comment: A&A, in pres