330 research outputs found
The BSM Physics Case of the ILC
In this talk I summarize the physics case of the International Linear
Collider (ILC) focusing on its potential towards discovery, discrimation or
disentanglement of new physics beyond the Standard Model (BSM).Comment: 8 pages, 2 figures, Talk presented at the International Workshop on
Future Linear Colliders (LCWS15), Whistler, Canada, 2-6 November 201
Top-Quark Physics at the LHC
We report on the precision determination of the top-quark mass to
next-to-next-to-leading order in QCD in well-defined renormalization schemes
using data from the Large Hadron Collider for single-top and top-quark pair
production. We also discuss the calibration of the so-called Monte Carlo
top-quark mass parameter which is determined from a comparison to events with
top-quark decay products. The implications of the measured value of the
top-quark mass for conclusions about the stability of the electroweak vacuum
state of our Universe are illustrated. At future lepton colliders, we provide
for the first time matched exclusive calculations valid both at the top
threshold and in the continuum, also fully differentially. In addition, we
calculate fully off-shell top-pair production (also with an associated Higgs
boson) at next-to-leading order in QCD, which allows to extract the top-Yukawa
coupling with an unprecedented precision.Comment: 15 pages, 8 figures. Part of the final report of the Collaborative
Research Center 676 "Particles, Strings and the Early Universe" 2006 - 201
Littlest Higgs with T-parity: Status and Prospects
The Littlest Higgs model with T-parity is providing an attractive solution to
the fine-tuning problem. This solution is only entirely natural if its
intrinsic symmetry breaking scale f is relatively close to the electroweak
scale. We examine the constraints using the latest results from the 8 TeV run
at the LHC. Both direct searches and Higgs precision physics are taken into
account. The constraints from Higgs couplings are by now competing with
electroweak precision tests and both combined exclude f up to 694 GeV or 560
GeV depending on the implementation of the down-type Yukawa sector. Direct
searches provide robust and complementary limits and constrain f to be larger
than 638 GeV. We show that the Littlest Higgs model parameter space is slowly
driven into the TeV range. Furthermore, we develop a strategy on how to
optimise present supersymmetry searches for the considered model, with the goal
to improve the constraints and yield more stringent limits on f.Comment: 43 pages, 16 figures, version 2 updated to JHEP 02 (2014) 05
CADISHI: Fast parallel calculation of particle-pair distance histograms on CPUs and GPUs
We report on the design, implementation, optimization, and performance of the
CADISHI software package, which calculates histograms of pair-distances of
ensembles of particles on CPUs and GPUs. These histograms represent 2-point
spatial correlation functions and are routinely calculated from simulations of
soft and condensed matter, where they are referred to as radial distribution
functions, and in the analysis of the spatial distributions of galaxies and
galaxy clusters. Although conceptually simple, the calculation of radial
distribution functions via distance binning requires the evaluation of
particle-pair distances where is the number of particles
under consideration. CADISHI provides fast parallel implementations of the
distance histogram algorithm for the CPU and the GPU, written in templated C++
and CUDA. Orthorhombic and general triclinic periodic boxes are supported, in
addition to the non-periodic case. The CPU kernels feature cache-blocking,
vectorization and thread-parallelization to obtain high performance. The GPU
kernels are tuned to exploit the memory and processor features of current GPUs,
demonstrating histogramming rates of up to a factor 40 higher than on a
high-end multi-core CPU. To enable high-throughput analyses of molecular
dynamics trajectories, the compute kernels are driven by the Python-based
CADISHI engine. It implements a producer-consumer data processing pattern and
thereby enables the complete utilization of all the CPU and GPU resources
available on a specific computer, independent of special libraries such as MPI,
covering commodity systems up to high-end HPC nodes. Data input and output are
performed efficiently via HDF5. (...) The CADISHI software is freely available
under the MIT license.Comment: 19 page
Effects of the Running of the QCD Coupling on the Energy Loss in the Quark-Gluon Plasma
Finite temperature modifies the running of the QCD coupling alpha_s(k,T) with
resolution k. After calculating the thermal quark and gluon masses
selfconsistently, we determine the quark-quark and quark-gluon cross sections
in the plasma based on the running coupling. We find that the running coupling
enhances these cross sections by factors of two to four depending on the
temperature. We also compute the energy loss dE/dx of a high-energy quark in
the plasma as a function of temperature. Our study suggests that, beside
t-channel processes, inverse Compton scattering is a relevant process for a
quantitative understanding of the energy loss of an incident quark in a hot
plasma.Comment: 14 pages, 6 figure
Selective non-steroidal glucocorticoid receptor agonists attenuate inflammation but do not impair intestinal epithelial cell restitution in vitro
Introduction: Despite the excellent anti-inflammatory and immunosuppressive action of glucocorticoids (GCs), their use for the treatment of inflammatory bowel disease (IBD) still carries significant risks in terms of frequently occurring severe side effects, such as the impairment of intestinal tissue repair. The recently-introduced selective glucocorticoid receptor (GR) agonists (SEGRAs) offer anti-inflammatory action comparable to that of common GCs, but with a reduced side effect profile.
Methods: The in vitro effects of the non-steroidal SEGRAs Compound A (CpdA) and ZK216348, were investigated in intestinal epithelial cells and compared to those of Dexamethasone (Dex). GR translocation was shown by immunfluorescence and Western blot analysis. Trans-repressive effects were studied by means of NF-κB/p65 activity and IL-8 levels, trans-activation potency by reporter gene assay. Flow cytometry was used to assess apoptosis of cells exposed to SEGRAs. The effects on IEC-6 and HaCaT cell restitution were determined using an in vitro wound healing model, cell proliferation by BrdU assay. In addition, influences on the TGF-β- or EGF/ERK1/2/MAPK-pathway were evaluated by reporter gene assay, Western blot and qPCR analysis.
Results: Dex, CpdA and ZK216348 were found to be functional GR agonists. In terms of trans-repression, CpdA and ZK216348 effectively inhibited NF-κB activity and IL-8 secretion, but showed less trans-activation potency. Furthermore, unlike SEGRAs, Dex caused a dose-dependent inhibition of cell restitution with no effect on cell proliferation. These differences in epithelial restitution were TGF-β-independent but Dex inhibited the EGF/ERK1/2/MAPK-pathway important for intestinal epithelial wound healing by induction of MKP-1 and Annexin-1 which was not affected by CpdA or ZK216348.
Conclusion: Collectively, our results indicate that, while their anti-inflammatory activity is comparable to Dex, SEGRAs show fewer side effects with respect to wound healing. The fact that SEGRAs did not have a similar effect on cell restitution might be due to a different modulation of EGF/ERK1/2 MAPK signalling
Parallel Adaptive Monte Carlo Integration with the Event Generator WHIZARD
We describe a new parallel approach to the evaluation of phase space for
Monte-Carlo event generation, implemented within the framework of the WHIZARD
package. The program realizes a twofold self-adaptive multi-channel
parameterization of phase space and makes use of the standard OpenMP and MPI
protocols for parallelization. The modern MPI3 feature of asynchronous
communication is an essential ingredient of the computing model. Parallel
numerical evaluation applies both to phase-space integration and to event
generation, thus covering the most computing-intensive parts of physics
simulation for a realistic collider environment.Comment: 28 pages, 4 figure
Theory requirements for SM Higgs and EW precision physics at the FCC-ee
High precision experimental measurements of the properties of the Higgs boson
at 125 GeV as well as electroweak precision observables such as the W
-boson mass or the effective weak leptonic mixing angle are expected at future
colliders such as the FCC-ee. This high anticipated precision has to
be matched with theory predictions for the measured quantities at the same
level of accuracy. We briefly summarize the status of these predictions within
the Standard Model (SM) and of the tools that are used for their determination.
We outline how the theory predictions will have to be improved in order to
reach the required accuracy, and also comment on the simulation frameworks for
the Higgs and EW precision program.Comment: Submitted to EPJ Plus, Focus Point on A future Higgs & Electroweak
factory (FCC): Challenges towards discovery (forthcoming). arXiv admin note:
substantial text overlap with arXiv:1906.0537
Discriminating Majorana and Dirac heavy neutrinos at lepton colliders
In this paper we investigate how well the nature of heavy neutral leptons can
be determined at a future lepton collider, after its potential discovery.
Considered in a simplified model are prompt decays of the neutrino in the mass
range from 100 GeV to 10 TeV. We study event selection and application of
multivariate analyses to determine whether such a newly discovered particle is
of the Dirac or Majorana nature. Combining lepton charge and kinematic event
variables, we find that the nature of a heavy neutrino, whether it is a Dirac
or a Majorana particle, can be determined at 95% C.L. almost in the whole
discovery range. We will briefly speculate about other than the studied
channels and the robustness of this statement in more general models of heavy
neutral leptons, particularly on the complementarity of high-energy
electron-positron vs. muon colliders on resolving the flavor structure of heavy
neutrinos
Simple, Parallel, High-Performance Virtual Machines for Extreme Computations
We introduce a high-performance virtual machine (VM) written in a numerically
fast language like Fortran or C to evaluate very large expressions. We discuss
the general concept of how to perform computations in terms of a VM and present
specifically a VM that is able to compute tree-level cross sections for any
number of external legs, given the corresponding byte code from the optimal
matrix element generator, O'Mega. Furthermore, this approach allows to
formulate the parallel computation of a single phase space point in a simple
and obvious way. We analyze hereby the scaling behaviour with multiple threads
as well as the benefits and drawbacks that are introduced with this method. Our
implementation of a VM can run faster than the corresponding native, compiled
code for certain processes and compilers, especially for very high
multiplicities, and has in general runtimes in the same order of magnitude. By
avoiding the tedious compile and link steps, which may fail for source code
files of gigabyte sizes, new processes or complex higher order corrections that
are currently out of reach could be evaluated with a VM given enough computing
power.Comment: 19 pages, 8 figure
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