Effect of Copper Slag and Granite Powder on the Mechanical Properties of Reclaimed Asphalt Pavement Aggregate Concrete

The replacement of natural gravel aggregate with reclaimed asphalt as coarse aggregate would help in reduction of environmental and ecological effects. Researches were rarely performed by replacing fine aggregate in reclaimed asphalt pavement aggregate concrete. This project aims to investigate the feasibility of improving the strength of recycled asphalt aggregate concrete in which recycled asphalt aggregate is used as a partial replacement of coarse aggregate at 30%. Abrasion and attrition technique is used to modify or roughen the surface of RAP aggregates. Granite powder and copper slag are used as a partial replacement of sand at 5, 10, 15, 20 and 25% in Abrasion and attrition Treated Reclaimed Asphalt Pavement Aggregate Concrete (ABTRAPC). Thirty cubes, twenty cylinders and twenty beams of concrete with granite powder and thirty cubes, twenty cylinders and ten beams of concrete with copper slag were made and tested. The 7th and 28th day strengths were found out at these replacements. It was observed that the compressive strength, split tensile strength and flexural strength was found to be maximum at 15% replacement of sand by copper slag. The compressive strength was increased about 29.8% compared to ABTRAPC. Flexural strength similar to normal concrete and about 12.8% greater compared to ABTRAP concrete. The compressive strength and flexural strength was also increased to a maximum at 15% replacement of sand by granite powder and split tensile strength at 20% replacement of granite powder. The results showed that the potential of reclaimed asphalt aggregates as a partial replacement of coarse aggregates in concrete could be effectively enhanced with its a combination with granite powder or copper slag. The increase in compressive strength values and the increase in flexural strength values similar to normal concrete proved that this concrete has its potential to be used in pavement applications

Low Cost, Efficient Output- Only Infrastructure Damage Detection with Wireless Sensor Networks

Sensor network comprises of sensors and actuators with universally useful processing components to agreeably screen physical or ecological conditions, for example, temperature, pressure, and so on. Wireless Sensor Networks are particularly portrayed by properties like the constrained power they can reap or store, dynamic network topology, expansive size of the arrangement. Sensor networks have an enormous application in fields which incorporates territory observing, object tracking, fire detection, landslide recognition and activity observing. Given the network topology, directing conventions in sensor networks can be named at based steering, various levelled based directing and area-based directing. Low Energy Adaptive Clustering Hierarchy (LEACH) is a vitality productive various levelled based steering convention. Our prime spotlight was on the examination of LEACH given specific parameters like network lifetime, soundness period, and so forth and furthermore the impact of particular sending assault and level of heterogeneity on LEACH convention

Heterogeneous Ensemble Variable Selection To Improve Customer Prediction Using Naive Bayes Model

The analysis of customer patterns and behaviours is essential for all businesses, as the customer is the sole source of revenue. Understanding customer patterns and behavior enables businesses to enhance their business processes and customer happiness. The availability of voluminous client datasets within organizations facilitates efficient customer analysis. Yet, the inclusion of interrelated, irrelevant, as well as missing factors leads to a poor forecast of the dataset. Feature selection techniques are investigated in order to handle the problem. Objective of feature selection is to pick the pertinent variables from a complete set of associated, irrelevant, and missing variables. In general, FS is classified into 3 types: filter, wrapper, & hybrid method. The filter method is a quick one, but the variables used are ineffective. Similarly, a wrapper method is effective yet computationally inefficient. In this study, an ensemble feature selection strategy is presented and tested to circumvent the issue with these feature selections. There are two techniques to ensemble FS: one is homogenous and the other is heterogeneous. This study employs a heterogeneous ensemble feature selection method. In the suggested method, the learning dataset is applied to five distinct filter FS approaches, and the ranked attributes that result are aggregated using two distinct methods: the mean method and the min method. Relevant variables are chosen to further build the final sorted qualities using the cut off value as a guide. As the HEVS technique's filter approach simply ranks the variables, it is necessary to select the variable subset cut off value. The experimental technique is conducted from two distinct vantage points: Heterogeneous ensemble variable selection with Naive Bayes and Naive Bayes without variable selection. In the end, the outcomes that were obtained via the use of the two different approaches are compared using different factors. The experimental results demonstrate that the suggested HEVS method outperforms the usual Naive Bayes model. As relevant variables are included when modeling using NB, the computational complexity of this proposed methodology is also minimized

Integration of epitaxial colossal magnetoresistive films onto Si(100) using SrTiO\u3csub\u3e3\u3c/sub\u3e as a template layer

We report on the integration of epitaxial colossal magnetoresistive La0.67Ba0.33MnO films on Si(100) semiconductor using SrTiO3 template layer by pulsed-laser deposition. X-ray diffraction reveals the superior quality of the manganite film that grows epitaxially on heteroepitaxially grown SrTiO3 template layer on Si substrate. The epitaxial films demonstrate remarkable surface morphology, magnetic transition and hysteresis, magnetoresistance, and ferromagnetic resonance, illustrating the ferromagnetic nature of the film and possible device applications at room temperature

De novo 7p partial trisomy characterized by subtelomeric FISH and whole-genome array in a girl with mental retardation

Chromosome rearrangements involving telomeres have been established as one of the major causes of idiopathic mental retardation/developmental delay. This case of 7p partial trisomy syndrome in a 3-year-old female child presenting with developmental delay emphasizes the clinical relevance of cytogenetic diagnosis in the better management of genetic disorders. Application of subtelomeric FISH technique revealed the presence of interstitial telomeres and led to the ascertainment of partial trisomy for the distal 7p segment localized on the telomeric end of the short arm of chromosome 19. Whole-genome cytogenetic microarray-based analysis showed a mosaic 3.5 Mb gain at Xq21.1 besides the approximately 24.5 Mb gain corresponding to 7p15.3- > pter. The possible mechanisms of origin of the chromosomal rearrangement and the clinical relevance of trisomy for the genes lying in the critical regions are discussed

Magnetic properties of La\u3csub\u3e0.60\u3c/sub\u3eSr\u3csub\u3e0.40\u3c/sub\u3eMnO\u3csub\u3e3\u3c/sub\u3e thin films on SrTiO\u3csub\u3e3\u3c/sub\u3e and buffered Si substrates with varying thickness

La0.60Sr0.40MnO3 (LSMO) thin films of varying thickness from 12 to 55 nm were deposited using the pulsed-laser deposition technique onto single-crystalline SrTiO3 (STO) and STO-buffered Si substrates. The T c of LSMO films grown on STO-buffered Si substrates decreases faster than films directly grown on STO with decreasing film thickness. The LSMO/STO film with thickness of 55 nm shows T c at about 360 K, which is close to the bulk value, whereas T c LSMO film on STO-buffered Si film of similar thickness is reduced to 320 K. This difference is attributed to the strain and interfacial disorders in LSMO film on STO/Si. The film surface morphology is influenced by the film thickness. Oxygenation of LSMO films on STO-buffered Si affects the T c minimally but improved the overall magnetization of the films due to better oxygenation, which is also the case for postannealing the sample at elevated temperatures. The thermomagnetic history effects observed in LSMO films of STO-buffered Si indicate the presence of inhomogeneity, mostly at the interface, which influences the magnetic properties significantly

The F0F1-ATP Synthase Complex Contains Novel Subunits and Is Essential for Procyclic Trypanosoma brucei

The mitochondrial F0F1 ATP synthase is an essential multi-subunit protein complex in the vast majority of eukaryotes but little is known about its composition and role in Trypanosoma brucei, an early diverged eukaryotic pathogen. We purified the F0F1 ATP synthase by a combination of affinity purification, immunoprecipitation and blue-native gel electrophoresis and characterized its composition and function. We identified 22 proteins of which five are related to F1 subunits, three to F0 subunits, and 14 which have no obvious homology to proteins outside the kinetoplastids. RNAi silencing of expression of the F1 α subunit or either of the two novel proteins showed that they are each essential for the viability of procyclic (insect stage) cells and are important for the structural integrity of the F0F1-ATP synthase complex. We also observed a dramatic decrease in ATP production by oxidative phosphorylation after silencing expression of each of these proteins while substrate phosphorylation was not severely affected. Our procyclic T. brucei cells were sensitive to the ATP synthase inhibitor oligomycin even in the presence of glucose contrary to earlier reports. Hence, the two novel proteins appear essential for the structural organization of the functional complex and regulation of mitochondrial energy generation in these organisms is more complicated than previously thought

Altered urothelial ATP signaling in a major subset of human overactive bladder patients with pyuria

Overactive Bladder (OAB) is an idiopathic condition, characterized by urgency, urinary frequency, and urgency incontinence, in the absence of routinely traceable urinary infection. We have described microscopic pyuria (?10 wbc/?l) in patients suffering from the worst symptoms. It is established that inflammation is associated with increased ATP release from epithelial cells, and extracellular ATP originating from the urothelium following increased hydrostatic pressure is a mediator of bladder sensation. Here, using bladder biopsy samples, we have investigated urothelial ATP signaling in OAB patients with microscopic pyuria. Basal, but not stretch-evoked, release of ATP was significantly greater from the urothelium of OAB patients with pyuria than from non-OAB patients or OAB patients without pyuria (<10 wbc/?l). Basal ATP release from the urothelium of OAB patients with pyuria was inhibited by the P2 receptor antagonist suramin and abolished by the hemichannel blocker carbenoxolone, which differed from stretch-activated ATP release. Altered P2 receptor expression was evident in the urothelium from pyuric OAB patients. Furthermore, intracellular bacteria were visualized in shed urothelial cells from ?80% of OAB patients with pyuria. These data suggest that increased ATP release from the urothelium, involving bacterial colonization, may play a role in the heightened symptoms associated with pyuric OAB patients

Global estimates on the number of people blind or visually impaired by cataract: a meta-analysis from 2000 to 2020

Background: To estimate global and regional trends from 2000 to 2020 of the number of persons visually impaired by cataract and their proportion of the total number of vision-impaired individuals. Methods: A systematic review and meta-analysis of published population studies and gray literature from 2000 to 2020 was carried out to estimate global and regional trends. We developed prevalence estimates based on modeled distance visual impairment and blindness due to cataract, producing location-, year-, age-, and sex-specific estimates of moderate to severe vision impairment (MSVI presenting visual acuity &lt;6/18, ≥3/60) and blindness (presenting visual acuity &lt;3/60). Estimates are age-standardized using the GBD standard population. Results: In 2020, among overall (all ages) 43.3 million blind and 295 million with MSVI, 17.0 million (39.6%) people were blind and 83.5 million (28.3%) had MSVI due to cataract blind 60% female, MSVI 59% female. From 1990 to 2020, the count of persons blind (MSVI) due to cataract increased by 29.7%(93.1%) whereas the age-standardized global prevalence of cataract-related blindness improved by −27.5% and MSVI increased by 7.2%. The contribution of cataract to the age-standardized prevalence of blindness exceeded the global figure only in South Asia (62.9%) and Southeast Asia and Oceania (47.9%). Conclusions: The number of people blind and with MSVI due to cataract has risen over the past 30 years, despite a decrease in the age-standardized prevalence of cataract. This indicates that cataract treatment programs have been beneficial, but population growth and aging have outpaced their impact. Growing numbers of cataract blind indicate that more, better-directed, resources are needed to increase global capacity for cataract surgery.</p