Вплив фактора конфігурації порожнини зуба на прогноз функціонування композитної реставрації

The development of the cavity configuration factor was substantiated by the necessity of quantifying the ratio of polymerization shrinkage and polymerization stress indicators in accordance with the peculiarities of the geometry of prepared carious defect. However, according to various studies, the level of distribution of polymerization stress more strongly depends on the absolute sizes of the investigated restoration samples, and not directly on the C-factor, however, it has not been adequately evidently interpreted from the point of view of the clinical significance for the obtained results. The aim of the study. To analyze the effect of the configuration factor of the prepared cavity on the success of the direct restorations function in the process of developing a model of predictive assessment of stress distribution at the interface of composite material and tooth tissues. Materials and methods. Google Scholar search form (http://scholar.google.com) was used with its advanced features for realization of study objective. The following sets of words «C-factor», «dental cavity configuration», «cavity geometry», «direct restoration», and «composite restoration» were used as header operators in various combinations, each resulting for the search of keywords combination represented as a set of academic papers on relevant topics, that were subsequently subject to content analysis. Results and discussion. Based on the literature data, the reduction of shrinkage stress was confirmed with the growth of the quantitative index of the C-factor and a decrease in the predictive index of the success of composite restoration represeted the similar trend. The C-factor in the range of 0,3-2,3 is not extremely critical in terms of the risk of microleakage formation between the composite and the tooth, as compared to indicators of the C-factor approaching 3,0. Conclusions. The further development of a complex model of finite elements with the representation in its structure elements of a different density (in particular, enamels, dentin, various composites) and the corresponding mathematical argumentation of the polymerization shrinkage and stress vectors, will allow to objectivize the cumulative effect of the C-factor on the success of the composite restoration function, proceeding from the poly-directional stresses at the bonding interface of the composite material and tooth tissues interface.Разработка параметра конфигурации полости была обоснована необходимостью квантификации соотношения показателей полимеризационной усадки и полимеризационного стресса в соответствии с особенностями геометрии отпрепарованного кариозного дефекта. Однако по данным различных исследований, уровень распределения полимеризационного стресса более выражено зависит от абсолютных размеров исследуемых образцов реставраций, а не непосредственно от показателя С-фактора, что однако не было в достаточной мере доказательно интерпретировано с точки зрения клинической значимости полученных результатов. Цель исследования – проанализировать влияние фактора конфигурации отпрепарированной полости на успешность функционирования прямых реставраций в процессе разработки модели прогностической оценки распределения напряжений на границе интерфейса композитного материала и тканей зуба. Материалы и методы. Для проведения поиска использовалась форма поиска Google Scholar (http://scholar.google.com) с применением ее расширенных функций. В результате использования операторов «поиск по фразе» и «в заголовке» были сформированы следующие наборы ключевых слов «С-factor», «dental cavity configuration», «cavity geometry», «direct restoration», «composite restoration», которые применялись в различных комбинациях. Каждый полученный результат поиска по комбинации ключевых слов представлял собой набор академических работ соответствующей тематики, которые в дальнейшем подлежали контент-анализа. Результаты исследований и их обсуждение. Исходя из приведенных литературных даннях, был подтвержден факт уменьшения уровня усадочного стресса при росте количественного показателя С-фактора и снижение прогностического показателя успешности композитной реставрации при аналогичной тенденции. Показатели С-фактора в диапазоне 0,3–2,3 не являются предельно критическими с точки зрения риска формирования микрозазора между композитом и стенкой зуба по сравнению с показателями С-фактора, приближающихся к 3,0. Выводы. Дальнейшая разработка сложной модели конечных элементов с репрезентацией в ее структуре элементов различной плотности (в частности эмали, дентина, различных композитных и прокладочных материалов) и соответствующей математической аргументацией векторов полимеризационной усадки и стресса, позволит объективизировать кумулятивное воздействие показателя С-фактора на успешность функционирования композитной реставрации, исходя из полинаправлености напряжений на границе бондингового интерфейса композитного материала и тканей зуба.Розробка параметра конфігурації порожнини була обґрунтована потребою квантифікації співвідношення показників полімеризаційної усадки та полімеризаційного стресу відповідно до особливостей геометрії відпрепарованого каріозного дефекту. Однак за даними різних досліджень, рівень розподілу полімеризаційного стресу вираженіше залежить від абсолютних розмірів досліджуваних зразків реставрацій, а не безпосередньо від показника С-фактора, що проте не було достатньою мірою доказово інтерпретовано з точки зору клінічної значимості отриманих результатів. Мета дослідження – проаналізувати вплив фактора конфігурації відпрепарованої порожнини на успішність функціонування прямих реставрацій у процесі розробки моделі прогностичної оцінки розподілу напруг на межі інтерфейсу композитного матеріалу та тканин зуба. Матеріали і методи. Для проведення пошуку використовували форму пошуку Google Scholar (http://scholar.google.com) із застосуванням її розширених функцій. У результаті застосування операторів «пошук за фразою» та «в заголовку» були сформовані наступні набори ключових слів «С-factor», «dental cavity configuration», «cavity geometry», «direct restoration», «composite restoration», які використовували у різних комбінаціях. Кожен отриманий результат пошуку за комбінацією ключових слів являв собою набір академічних робіт відповідної тематики, які в подальшому підлягали контент-аналізу. Результати досліджень та їх обговорення. Виходячи із наведених літературних даних, було підтверджено, що зменшення рівня усадкового стресу при зростанні кількісного показника С-фактора та зниження прогностичного показника успішності композитної реставрації при аналогічній тенденції. Показники С-фактору у діапазоні 0,3–2,3 не є гранично критичними з точки зору ризику формування мікропроміжку між композитом та стінкою зуба порівняно із показниками С-фактора, що наближаються до 3,0. Висновки. Подальша розробка складної моделі скінчених елементів із репрезентацією у її структурі елементів різної щільності (зокрема емалі, дентину, різних композитних та прокладочних матеріалів) та відповідною математичною аргументацією векторів полімеризаційної усадки та стресу, дозволить об’єктивізувати кумулятивний вплив показника С-фактора на успішність функціонування композитної реставрації, виходячи із полінаправленості напруг на межі бондингового інтерфейсу композитного матеріалу та тканин зуба

COMPARATIVE ANALYSIS OF THE MAJOR DENTAL PATHOLOGIES PREVALENCE AMONG CHILDREN OF TRANSCARPATHIAN REGION ACCORDING TO THE DATA OF THE STUDIED CLINICAL SAMPLE AND PRELIMINARY PERFORMED DENTAL RESEARCH

Taking into account the presence of pre-conducted epidemiological studies on the territory of Transcarpathian region devoted to the question of major dental pathologies prevalence among children, it is advisable to systematize and compare their results with each other, as well as with data obtained during a specifically formed study sample of children and adolescents. The aim of the study – to provide a comparative analysis of the major dental pathologies prevalence among children of Transcarpathian region according to the data of the studied clinical sample and preliminary performed dental populational studies. Materials and Methods. For the realization of the formulated research objective, a retrospective analysis of medical records and a dental examination of 411 children and adolescents were provided on the base of University Dental Clinic (Uzhhorod National University). Categorization of patients was provided due to their age-related passport indices with the formation and distribution of subgroups with a 1-year difference. Google Scholar search form (http://scholar.google.com) was used with its advanced features for the systematization of previously conducted studies aimed at registration of major dental pathologies among children of Transcarpathian region. The following sets of words «dental disease», «children» and «Transcarpathian region» were used as header operators in various combinations, each resulting for the set of academic papers on relevant topics, that were subsequently subject to content analysis. Results and Discussion. The average caries prevalence among studied clinical sample of 411 pediatric patients in the age range of 6.0–15.9 years was 73.2 % (included in the range of results provided by pre-conducted epidemiological studies), the average teeth crowding prevalence in the age range of 6.0–15.9 years was 18.82 % (below the range of results provided by pre-conducted epidemiological studies), the average dystopia prevalence in the age range of 6.0–15.9 years was 14.69 % (included in the range of results provided by pre-conducted epidemiological studies), the average primary edentulism prevalence in the age range of 6.0–15.9 years was 2.31 % (included in the range of results provided by pre-conducted epidemiological studies), the average super numerary teeth prevalence in the age range of 6.0–15.9 years was 0.82 % (included in the range of results provided by pre-conducted epidemiological studies), the average delay in teeth eruption prevalence in the age range of 6–15.9 years was noted in 8.65 % of clinical cases (included in the range of results provided by pre-conducted epidemiological studies). Conclusions. Thus, in the course of this phase of study, which was aimed to provide comparative analysis of the major dental pathologies prevalence among children and adolescents, and was conducted through a retrospective review of medical documentation and examination of 411 dental pediatric patients, it was found that the established prevalence of different pathologies does not statistically differ from the indicators, which were given in previous epidemiological studies. The small absolute difference of the indicators can be justified by the discrepancy in the size of samples being studied, the analysis of the certain pathologies prevalence outside Transcarpathian regions, the discrepancy in age categorization given in various studies, the researches of the stomatological status of the children's population living in different regions of Transcarpathia

BioCloud: a resource provisioning framework for bioinformatics applications in multi-cloud environments

The significant advancement in Next Generation Sequencing (NGS) have enabled the generation of several gigabytes of raw data in a single sequencing run. This amount of raw data introduces new scalability challenges in processing, storing and analyzing it, which cannot be solved using a single workstation, the only resource available for the majority of biological scientists, in a reasonable amount of time. These scalability challenges can be complemented by provisioning computational and storage resources using Cloud Computing in a cost-effective manner. There are multiple cloud providers offering cloud resources as a utility within various business models, service levels and functionalities. However, the lack of standards in cloud computing leads to interoperability issues among the providers rendering the selected one unalterable. Furthermore, even a single provider offers multiple configurations to choose from. Therefore, it is essential to develop a decision making system that facilitates the selection of the suitable cloud provider and configuration together with the capability to switch among multiple providers in an efficient and transparent manner. In this paper, we propose BioCloud as a single point of entry to a multi-cloud environment for non-computer savvy bio-researchers. We discuss the architecture and components of BioCloud and present the scheduling algorithm employed in BioCloud. Experiments with different use-cases and scenarios reveal that BioCloud can decrease the workflow execution time for a given budget while encapsulating the complexity of resource management in multiple cloud providers

Non-local rheology in dense granular flows -- Revisiting the concept of fluidity

Granular materials belong to the class of amorphous athermal systems, like foams, emulsion or suspension they can resist shear like a solid, but flow like a liquid under a sufficiently large applied shear stress. They exhibit a dynamical phase transition between static and flowing states, as for phase transitions of thermodynamic systems, this rigidity transition exhibits a diverging length scales quantifying the degree of cooperatively. Several experiments have shown that the rheology of granular materials and emulsion is non-local, namely that the stress at a given location does not depend only on the shear rate at this location but also on the degree of mobility in the surrounding region. Several constitutive relations have recently been proposed and tested successfully against numerical and experimental results. Here we use discrete elements simulation of 2D shear flows to shed light on the dynamical mechanism underlying non-locality in dense granular flows

Validation of the Short Version (TLS-15) of the Triangular Love Scale (TLS-45) Across 37 Languages

Love is a phenomenon that occurs across the world and affects many aspects of human life, including the choice of, and process of bonding with, a romantic partner. Thus, developing a reliable and valid measure of love experiences is crucial. One of the most popular tools to quantify love is Sternberg’s 45-item Triangular Love Scale (TLS-45), which measures three love components: intimacy, passion, and commitment. However, our literature review reveals that most studies (64%) use a broad variety of shortened versions of the TLS-45. Here, aiming to achieve scientific consensus and improve the reliability, comparability, and generalizability of results across studies, we developed a short version of the scale—the TLS-15—comprised of 15 items with 5-point, rather than 9-point, response scales. In Study 1 (N = 7,332), we re-analyzed secondary data from a large-scale multinational study that validated the original TLS-45 to establish whether the scale could be truncated. In Study 2 (N = 307), we provided evidence for the three-factor structure of the TLS-15 and its reliability. Study 3 (N = 413) confirmed convergent validity and test–retest stability of the TLS-15. Study 4 (N = 60,311) presented a large-scale validation across 37 linguistic versions of the TLS-15 on a cross-cultural sample spanning every continent of the globe. The overall results provide support for the reliability, validity, and cross-cultural invariance of the TLS-15, which can be used as a measure of love components—either separately or jointly as a three-factor measure

Predictors of Enhancing Human Physical Attractiveness: Data from 93 Countries

People across the world and throughout history have gone to great lengths to enhance their physical appearance. Evolutionary psychologists and ethologists have largely attempted to explain this phenomenon via mating preferences and strategies. Here, we test one of the most popular evolutionary hypotheses for beauty-enhancing behaviors, drawn from mating market and parasite stress perspectives, in a large cross-cultural sample. We also test hypotheses drawn from other influential and non-mutually exclusive theoretical frameworks, from biosocial role theory to a cultural media perspective. Survey data from 93,158 human participants across 93 countries provide evidence that behaviors such as applying makeup or using other cosmetics, hair grooming, clothing style, caring for body hygiene, and exercising or following a specific diet for the specific purpose of improving ones physical attractiveness, are universal. Indeed, 99% of participants reported spending \u3e10 min a day performing beauty-enhancing behaviors. The results largely support evolutionary hypotheses: more time was spent enhancing beauty by women (almost 4 h a day, on average) than by men (3.6 h a day), by the youngest participants (and contrary to predictions, also the oldest), by those with a relatively more severe history of infectious diseases, and by participants currently dating compared to those in established relationships. The strongest predictor of attractiveness-enhancing behaviors was social media usage. Other predictors, in order of effect size, included adhering to traditional gender roles, residing in countries with less gender equality, considering oneself as highly attractive or, conversely, highly unattractive, TV watching time, higher socioeconomic status, right-wing political beliefs, a lower level of education, and personal individualistic attitudes. This study provides novel insight into universal beauty-enhancing behaviors by unifying evolutionary theory with several other complementary perspectives

Mononuclear and Mixed-Metal Dimethyltin Pacman Complexes of a Schiff-Base Pyrrole Macrocycle

The synthesis of the dialkyltin complex [SnMe2-(H2L)] of an octadentate Schiff-base pyrrol macrocycle is described in which the gross Pacman geometry enforces structural discrimination between the two methyl groups. The presence of the metal-free compertment engenders the formation of mixed-metal Sn-Fe and Sn-Zn complexes in which the macrocyclic cleft has distorted considerably upon the introduction of the transition metal cation.</p

Sex differences in mate preferences across 45 countries: A large-scale replication

Considerable research has examined human mate preferences across cultures, finding universal sex differences in preferences for attractiveness and resources as well as sources of systematic cultural variation. Two competing perspectives—an evolutionary psychological perspective and a biosocial role perspective—offer alternative explanations for these findings. However, the original data on which each perspective relies are decades old, and the literature is fraught with conflicting methods, analyses, results, and conclusions. Using a new 45-country sample (N = 14,399), we attempted to replicate classic studies and test both the evolutionary and biosocial role perspectives. Support for universal sex differences in preferences remains robust: Men, more than women, prefer attractive, young mates, and women, more than men, prefer older mates with financial prospects. Cross-culturally, both sexes have mates closer to their own ages as gender equality increases. Beyond age of partner, neither pathogen prevalence nor gender equality robustly predicted sex differences or preferences across countries

Purloined letters: the Aristonothos inscription and crater

The Greek colonies of the Western Mediterranean were central to the evolution of many aspects of Greek culture and in many cases developed an identity which was significantly different from that of mainland Greece and the Aegean. This volume seeks to explore aspects of the cultural identity of these colonies and how it evolved. It covers the colonial foundations in Italy, Sicily, Southern France, Spain and North Africa, and ranges from the 8th century BC to the early Roman empire. Topics covered include the ethnic identity of the earliest colonial foundations, the evolution of Greek states in the West, the Greeks' perceptions of their own identity and ways of representing it, and the role of the indigenous populations in the evolution of Western Greek culture

A resource provisioning framework for bioinformatics applications in multi-cloud environments

The significant advancement in Next Generation Sequencing (NGS) have enabled the generation of several gigabytes of raw data in a single sequencing run. This amount of raw data introduces new scalability challenges in processing, storing and analyzing it, which cannot be solved using a single workstation, the only resource available for the majority of biological scientists, in a reasonable amount of time. These scalability challenges can be complemented by provisioning computational and storage resources using Cloud Computing in a cost-effective manner. There are multiple cloud providers offering cloud resources as a utility within various business models, service levels and functionalities. However, the lack of standards in cloud computing leads to interoperability issues among the providers rendering the selected one unalterable. Furthermore, even a single provider offers multiple configurations to choose from. Therefore, it is essential to develop a decision making system that facilitates the selection of the suitable cloud provider and configuration together with the capability to switch among multiple providers in an efficient and transparent manner. In this paper, we propose BioCloud as a single point of entry to a multi-cloud environment for non-computer savvy bio-researchers. We discuss the architecture and components of BioCloud and present the scheduling algorithm employed in BioCloud. Experiments with different use-cases and scenarios reveal that BioCloud can decrease the workflow execution time for a given budget while encapsulating the complexity of resource management in multiple cloud providers