HIV, hepatitis C virus, and hepatitis B virus co-infections among injecting drug users in Tehran, Iran

SummaryObjectivesTo assess the prevalence of HIV, hepatitis B virus (HBV) and hepatitis C virus (HCV) infections and co-infections among injecting drug users (IDUs) in Tehran.MethodsA sample of 899 IDUs (861 male and 38 female) was recruited in Tehran from treatment and harm reduction facilities and from drug user hangouts in public areas in equal proportions. ELISA testing for HIV, HCV antibody (HCV-Ab), hepatitis B surface antigen (HBsAg), and hepatitis B core antibody (HBcAb) was carried out. Positive HIV tests were rechecked by Western blot.ResultsThe prevalence of HIV was 10.7%, HCV infection was 34.5%, and past or current HBV infection was 50.7%. Infection with all three viruses was seen in 6.5% (95% confidence interval 4.9–8.2) of participants. HIV/HCV, HIV/HBV, and HBV/HCV co-infections were seen in 8.7%, 7.8%, and 21.0% of participants, respectively. The rate of HCV infection among HIV-positive cases was significantly higher than in HIV-negative IDUs (80.6% vs. 28.7%, p<0.0001). There was no significant association between these infections and co-infections with gender and source of sampling.ConclusionIn general, co-infection with these three blood-borne viruses is common among IDUs. Since co-infection increases the morbidity and mortality of all infections, the observed level of co-infection in the high number of IDUs in Iran necessitates a serious comprehensive response

Molecular identification and phylogeny of Nerita᾽s species on rocky shores of the Northern Persian Gulf

Neritas are among the most dominant groups of Gastropoda in the Persian Gulf. There is no previous study in relation to molecular and phylogeny of Neritas in the study area. The molecular identification of Nerita species have been studied for the first time in the northern rocky coastal zones of Persian Gulf during 2013 and 2014. After morphological identifications of species, DNA extraction, amplifying partial of cytochrome oxidase COI and 16S rRNA and sequencing procedure were done in the laboratory. In this study, 6 COI and 6 16S rRNA sequences, belonging to 3 species, were obtained. Also, phylogeny analyses with drawing phylogeny trees of Maximum Likelihood and Bayesian were done using MEGA6 and BEAST softwares. Morphological and molecular identification results were similar for 2 species and dissimilar for one species. This discrepancy shows that a combination of morphological and molecular studies is more reliable for species identification than either of them solely. The results also showed that Nerita species are monophyletic

Torque-assisting Compressed Air Energy Storage Hydraulic Wind Drivetrains

In this paper, Compressed Air Energy Storage (CAES) as a popular technology for wind energy storage, is mathematically integrated with a hydraulic wind power system. Hydraulic machinery as prime-movers is utilized to gain the benefit of eliminating costly and heavy gearboxes. The goal of this work is to improve the power delivery performance while maintaining a stable frequency generation in a 600kW hydraulic wind power system. Simulation results demonstrate that the integration of compressed air energy storage has improved the quality of power delivery such that the maximum power demand can be delivered while maintaining the frequency under variable wind speeds

A Generalized FDM for solving the Poisson's Equation on 3D Irregular Domains

In this paper a new method for solving the Poisson's equation with Dirichlet conditions on irregular domains is presented. For this purpose a generalized finite differences method is applied for numerical differentiation on irregular meshes. Three examples on cylindrical and spherical domains are considered. The numerical results are compared with analytical solution. These results show the performance and efficiency of the proposed method

A New Method for Solving 3D Elliptic Problem with Dirichlet or Neumann Boundary Conditions Using Finite Difference Method

Abstract In this paper, a new algorithm for solving general three dimensional linear Elliptic types P.D.E.&apos;s applying finite difference method is introduced. In this method, the boundary conditions are considered as auxiliary equations coupling with the main equations to constitute a system of linear equations, using suitable finite difference partial derivatives. The mesh points are also generated simply by proposed algorithm. This algorithm can perform numbering of mesh points, generating matrix coefficient, and right hand side vector by a special automatic procedure. Numerical experiments are presented to show performance, reliability and efficiency of proposed algorithm

The prevalence of smoking among Iranian middle school students, a systematic review

"n&nbsp;Objectives: "n "nThe mean age of cigarette smoking has decreased along with an increase in its prevalence, in developing countries. The aim of this systematic review is to determine the prevalence of lifetime, current and daily smoking among middle school students in Iran . "nMethods: Various search methods have been used in this study including searching different international databanks such as Pubmed, ISI web of Science, PsychInfo, CINAHL, Embase, as well as domestic databanks including IranPsych and IranMedex. All original studies and researches in Persian or English, which had described any kind of use including lifetime, current and daily use of cigarette, hookah, and pipe among middle school students, were included in the study with no restriction on date of publication, and were qualitatively assessed. Subsequent to data extraction, heterogeneity test was carried out on indicators for which more than two studies were found, and meta-analysis was done using random effects model . "nResults: The combined prevalence of lifetime, current and daily cigarette smoking were calculated as 14.2% (95% CI: 6.6-21.7), 2.7% (95% CI: 0.5- 5.9) and 1.1% (95% CI: 0.6-2.8), respectively. The combined prevalence of "current tobacco use of all kinds" was 15% (95% CI: 10.4-19.5), as well. "nConclusions: The prevalence of smoking in this age range is lower in Iran compared to other countries. However, a conclusion cannot be made about the changes in the prevalence of smoking in recent years. Moreover, studies carried out to the present have several qualitative limitations, which points to the necessity of high quality repeated survey