Coherent resonant tunneling in ac fields

We have analyzed the tunneling transmission probability and electronic current density through resonant heterostructures in the presence of an external electromagnetic field. In this work, we compare two different models for a double barrier : In the first case the effect of the external field is taken into account by spatially dependent AC voltages and in the second one the electromagnetic field is described in terms of a photon field that irradiates homogeneously the whole sample. While in the first description the tunneling takes place mainly through photo sidebands in the case of homogeneous illumination the main effective tunneling channels correspond to the coupling between different electronic states due to photon absorption and emission. The difference of tunneling mechanisms between these configurations is strongly reflected in the transmission and current density which present very different features in both cases. In order to analyze these effects we have obtained, within the Transfer Hamiltonian framework, a general expression for the transition probability for coherent resonant tunneling in terms of the Green's function of the system.Comment: 16 pages,Figures available upon request,to appear in Phys.Rev B (15 April 1996

Control of polymorphic transition inducing preferential enrichment

Preferential enrichment is an unusual symmetry-breaking enantiomeric resolution phenomenon that is initiated by the solvent-assisted solid-to-solid transformation of a metastable polymorphic form into a thermodynamically stable one during crystallization from the supersaturated solution of a certain kind of racemic crystals. On the basis of the proposed mechanism of preferential enrichment, both induction and inhibition of preferential enrichment were successfully achieved by controlling the mode of the polymorphic transition during crystallization either by minor molecular modification or with appropriate seed crystals. Furthermore, by inducing a desired polymorphic transition during crystallization of several α-amino acids or their cocrystals with dicarboxylic acids, which were classified as a racemic compound, preferential enrichment could also be accomplished

Unbounded-Error Classical and Quantum Communication Complexity

Since the seminal work of Paturi and Simon \cite[FOCS'84 & JCSS'86]{PS86}, the unbounded-error classical communication complexity of a Boolean function has been studied based on the arrangement of points and hyperplanes. Recently, \cite[ICALP'07]{INRY07} found that the unbounded-error {\em quantum} communication complexity in the {\em one-way communication} model can also be investigated using the arrangement, and showed that it is exactly (without a difference of even one qubit) half of the classical one-way communication complexity. In this paper, we extend the arrangement argument to the {\em two-way} and {\em simultaneous message passing} (SMP) models. As a result, we show similarly tight bounds of the unbounded-error two-way/one-way/SMP quantum/classical communication complexities for {\em any} partial/total Boolean function, implying that all of them are equivalent up to a multiplicative constant of four. Moreover, the arrangement argument is also used to show that the gap between {\em weakly} unbounded-error quantum and classical communication complexities is at most a factor of three.Comment: 11 pages. To appear at Proc. ISAAC 200

The Magic Number Problem for Subregular Language Families

We investigate the magic number problem, that is, the question whether there exists a minimal n-state nondeterministic finite automaton (NFA) whose equivalent minimal deterministic finite automaton (DFA) has alpha states, for all n and alpha satisfying n less or equal to alpha less or equal to exp(2,n). A number alpha not satisfying this condition is called a magic number (for n). It was shown in [11] that no magic numbers exist for general regular languages, while in [5] trivial and non-trivial magic numbers for unary regular languages were identified. We obtain similar results for automata accepting subregular languages like, for example, combinational languages, star-free, prefix-, suffix-, and infix-closed languages, and prefix-, suffix-, and infix-free languages, showing that there are only trivial magic numbers, when they exist. For finite languages we obtain some partial results showing that certain numbers are non-magic.Comment: In Proceedings DCFS 2010, arXiv:1008.127

Finite formation time effects in quasi-elastic (e,e′)(e,e') scattering on nuclear targets

The problem of the final state interaction in quasi-elastic $(e,e')$ scattering at large $Q^2$, is investigated by exploiting the idea that the ejected nucleon needs a finite amount of time to assume its asymptotic form. It is shown that when the dependence of the scattering amplitude of the ejected nucleon on its virtuality is taken into account, the final state interaction is decreased. The developed approach is simpler to implement than the one based on the color transparency description of the damping of the final state interaction, and is essentially equivalent to the latter in the case of the single rescattering term. The $(e,e')$ process on the deuteron is numerically investigated and it is shown that, at $x=1$, appreciable finite formation time effects at $Q^2$ of the order of 10 (GeV/c)$^2$ are expected.Comment: 23 pages, 3 figure

Reciprocal Roles for CCAAT/Enhancer Binding Protein (C/EBP) and PU.1 Transcription Factors in Langerhans Cell Commitment

Myeloid progenitor cells give rise to a variety of progenies including dendritic cells. However, the mechanism controlling the diversification of myeloid progenitors into each progeny is largely unknown. PU.1 and CCAAT/enhancing binding protein (C/EBP) family transcription factors have been characterized as key regulators for the development and function of the myeloid system. However, the roles of C/EBP transcription factors have not been fully identified because of functional redundancy among family members. Using high titer–retroviral infection, we demonstrate that a dominant-negative C/EBP completely blocked the granulocyte–macrophage commitment of human myeloid progenitors. Alternatively, Langerhans cell (LC) commitment was markedly facilitated in the absence of tumor necrosis factor (TNF)α, a strong inducer of LC development, whereas expression of wild-type C/EBP in myeloid progenitors promoted granulocytic differentiation, and completely inhibited TNFα-dependent LC development. On the other hand, expression of wild-type PU.1 in myeloid progenitors triggered LC development in the absence of TNFα, and its instructive effect was canceled by coexpressed C/EBP. Our findings establish reciprocal roles for C/EBP and PU.1 in LC development, and provide new insight into the molecular mechanism of LC development, which has not yet been well characterized

Many-to-one matchings with lower quotas : algorithms and complexity

We study a natural generalization of the maximum weight many-to-one matching problem. We are given an undirected bipartite graph G = (AUP,E) with weights on the edges in E, and with lower and upper quotas on the vertices in P. We seek a maximum weight many-toone matching satisfying two sets of constraints: vertices in A are incident to at most one matching edge, while vertices in P are either unmatched or they are incident to a number of matching edges between their lower and upper quota. This problem, which we call maximum weight many-toone matching with lower and upper quotas (wmlq), has applications to the assignment of students to projects within university courses, where there are constraints on the minimum and maximum numbers of students that must be assigned to each project. In this paper, we provide a comprehensive analysis of the complexity of wmlq from the viewpoints of classic polynomial time algorithms, fixed-parameter tractability, as well as approximability. We draw the line between NP-hard and polynomially tractable instances in terms of degree and quota constraints and provide efficient algorithms to solve the tractable ones. We further show that the problem can be solved in polynomial time for instances with bounded treewidth; however, the corresponding runtime is exponential in the treewidth with the maximum upper quota umax as basis, and we prove that this dependence is necessary unless FPT = W[1]. Finally, we also present an approximation algorithm for the general case with performance guarantee umax+1, which is asymptotically best possible unless P = NP

Paired Activating and Inhibitory Immunoglobulin-like Receptors, MAIR-I and MAIR-II, Regulate Mast Cell and Macrophage Activation

Immune responses are regulated by opposing positive and negative signals triggered by the interaction of activating and inhibitory cell surface receptors with their ligands. Here, we describe novel paired activating and inhibitory immunoglobulin-like receptors, designated myeloid-associated immunoglobulin-like receptor (MAIR) I and MAIR-II, whose extracellular domains are highly conserved by each other. MAIR-I, expressed on the majority of myeloid cells, including macrophages, granulocytes, mast cells, and dendritic cells, contains the tyrosine-based sorting motif and the immunoreceptor tyrosine-based inhibitory motif-like sequences in the cytoplasmic domain and mediates endocytosis of the receptor and inhibition of IgE-mediated degranulation from mast cells. On the other hand, MAIR-II, expressed on subsets of peritoneal macrophages and B cells, associates with the immunoreceptor tyrosine-based activation motif-bearing adaptor DAP12 and stimulates proinflammatory cytokines and chemokine secretions from macrophages. Thus, MAIR-I and MAIR-II play important regulatory roles in cell signaling and immune responses

Severe airway stenosis associated with Crohn's disease: Case report

BACKGROUND: Symptomatic respiratory tract involvement is not common in Crohn's disease. Upper-airway obstruction has been reported before in Crohn's disease and usually responds well to steroid treatment. CASE PRESENTATION: We report a case of a 32-year old patient with Crohn's disease who presented with progressively worsening dyspnea on exertion. Magnetic Resonance Imaging of the chest and bronchoscopy revealed severe tracheal stenosis and marked inflammation of tracheal mucosa. Histopathology of the lesion showed acute and chronic inflammation and extended ulceration of bronchial mucosa, without granulomas. Tracheal stenosis was attributed to Crohn's disease after exclusion of other possible causes and oral and inhaled steroids were administered. Despite steroid treatment, tracheal stenosis persisted and only mild symptomatic improvement was noted after 8 months of therapy. The patient subsequently underwent rigid bronchoscopy with successful dilatation and ablation of the stenosed areas and remission of her symptoms. CONCLUSION: Respiratory involvement in Crohn's disease might be more common than appreciated. Interventional pulmonology techniques should be considered in cases of tracheal stenosis due to Crohn's disease refractory to steroid treatment