Possibilities of Long-Range Forecast of Weather Conditions over the Antarctic Peninsula

Developed by us in 1998 the method of long-range weather forecast for the moderate latitudes of Northern hemisphere is based on two-month similarity of atmospheric circulation which is well revealed by the traditional method of analogues of one season. That is why similarity of atmospheric processes in the non-tropical latitudes of Southern hemisphere was also explored by the method of traditional analogue. Similarity between the processes of successive days on the fixed territory taking into account the coincidence of all geographical coordinates allowed to set in Southern hemisphere two-month quasi-periodicity of large-scale and consequently regional atmospheric circulation.Разработанный нами в 1998 г. метод долгосрочного прогноза погоды для умеренных широт Северного полушария основан на двухмесячной аналогичности атмосферной циркуляции, которая хорошо выявляется с помощью традиционного метода аналогов одного сезона. Потому аналогичность атмосферных процессов во внетропических широтах Южного полушария также была исследована с помощью метода традиционного аналога. Аналогичность между процессами последовательных дней на фиксированной территории с учетом совпадения всех географических координат позволила установить в Южном полушарии двухмесячную квазипериодичность крупномасштабной, и следовательно региональной, циркуляции атмосферы

Fungal Planet description sheets: 1284–1382

Novel species of fungi described in this study include those from various countries as follows: Antartica, Cladosporium austrolitorale from coastal sea sand. Australia, Austroboletus yourkae on soil, Crepidotus innuopurpureus on dead wood, Curvularia stenotaphri from roots and leaves of Stenotaphrum secundatum and Thecaphora stajsicii from capsules of Oxalis radicosa. Belgium, Paraxerochrysium coryli (incl. Paraxerochrysium gen. nov.) from Corylus avellana. Brazil, Calvatia nordestina on soil, Didymella tabebuiicola from leaf spots on Tabebuia aurea, Fusarium subflagellisporum from hypertrophied floral and vegetative branches of Mangifera indica and Microdochium maculosum from living leaves of Digitaria insularis. Canada, Cuphophyllus bondii fromagrassland. Croatia, Mollisia inferiseptata from a rotten Laurus nobilis trunk. Cyprus, Amanita exilis oncalcareoussoil. Czech Republic, Cytospora hippophaicola from wood of symptomatic Vaccinium corymbosum. Denmark, Lasiosphaeria deviata on pieces of wood and herbaceousdebris. Dominican Republic, Calocybella goethei among grass on a lawn. France (Corsica) , Inocybe corsica onwetground. France (French Guiana) , Trechispora patawaensis on decayed branch of unknown angiosperm tree and Trechispora subregularis on decayed log of unknown angiosperm tree. Germany, Paramicrothecium sambuci (incl. Paramicrothecium gen. nov.)ondeadstemsof Sambucus nigra. India, Aureobasidium microtermitis from the gut of a Microtermes sp. termite, Laccaria diospyricola on soil and Phylloporia tamilnadensis on branches of Catunaregam spinosa. Iran, Pythium serotinoosporum from soil under Prunus dulcis. Italy, Pluteus brunneovenosus on twigs of broad leaved trees on the ground. Japan, Heterophoma rehmanniae on leaves of Rehmannia glutinosa f. hueichingensis. Kazakhstan, Murispora kazachstanica from healthy roots of Triticum aestivum. Namibia, Caespitomonium euphorbiae (incl. Caespitomonium gen. nov.)from stems of an Euphorbia sp. Netherlands, Alfaria junci, Myrmecridium junci, Myrmecridium juncicola, Myrmecridium juncigenum, Ophioceras junci, Paradinemasporium junci (incl. Paradinemasporium gen. nov.), Phialoseptomonium junci, Sporidesmiella juncicola, Xenopyricularia junci and Zaanenomyces quadripartis (incl. Zaanenomyces gen. nov.), fromdeadculmsof Juncus effusus, Cylindromonium everniae and Rhodoveronaea everniae from Evernia prunastri, Cyphellophora sambuci and Myrmecridium sambuci from Sambucus nigra, Kiflimonium junci, Saro cladium junci, Zaanenomyces moderatricis academiae and Zaanenomyces versatilis from dead culms of Juncus inflexus, Microcera physciae from Physcia tenella, Myrmecridium dactylidis from dead culms of Dactylis glomerata, Neochalara spiraeae and Sporidesmium spiraeae from leaves of Spiraea japonica, Neofabraea salicina from Salix sp., Paradissoconium narthecii (incl. Paradissoconium gen. nov.)from dead leaves of Narthecium ossifragum, Polyscytalum vaccinii from Vaccinium myrtillus, Pseudosoloacrosporiella cryptomeriae (incl. Pseudosoloacrosporiella gen. nov.)fromleavesof Cryptomeria japonica, Ramularia pararhabdospora from Plantago lanceolata, Sporidesmiella pini from needles of Pinus sylvestris and Xenoacrodontium juglandis (incl. Xenoacrodontium gen. nov. and Xenoacrodontiaceae fam. nov.)from Juglans regia. New Zealand, Cryptometrion metrosideri from twigs of Metrosideros sp., Coccomyces pycnophyllocladi from dead leaves of Phyllocladus alpinus, Hypoderma aliforme from fallen leaves Fuscopora solandri and Hypoderma subiculatum from dead leaves Phormium tenax. Norway, Neodevriesia kalakoutskii from permafrost and Variabilispora viridis from driftwood of Picea abies. Portugal, Entomortierella hereditatis from abio film covering adeteriorated limestone wall. Russia, Colpoma junipericola from needles of Juniperus sabina, Entoloma cinnamomeum on soil in grasslands, Entoloma verae on soil in grasslands, Hyphodermella pallidostraminea on a dry dead branch of Actinidia sp., Lepiota sayanensis onlitterinamixedforest, Papiliotrema horticola from Malus communis , Paramacroventuria ribis (incl. Paramacroventuria gen. nov.)fromleaves of Ribes aureum and Paramyrothecium lathyri from leaves of Lathyrus tuberosus. South Africa, Harzia combreti from leaf litter of Combretum collinum ssp. sulvense, Penicillium xyleborini from Xyleborinus saxesenii , Phaeoisaria dalbergiae from bark of Dalbergia armata, Protocreopsis euphorbiae from leaf litter of Euphorbia ingens and Roigiella syzygii from twigs of Syzygium chordatum. Spain, Genea zamorana on sandy soil, Gymnopus nigrescens on Scleropodium touretii, Hesperomyces parexochomi on Parexochomus quadriplagiatus, Paraphoma variabilis from dung, Phaeococcomyces kinklidomatophilus from a blackened metal railing of an industrial warehouse and Tuber suaveolens in soil under Quercus faginea. Svalbard and Jan Mayen, Inocybe nivea associated with Salix polaris. Thailand, Biscogniauxia whalleyi oncorticatedwood. UK, Parasitella quercicola from Quercus robur. USA , Aspergillus arizonicus from indoor air in a hospital, Caeliomyces tampanus (incl. Caeliomyces gen. nov.)fromoffice dust, Cippumomyces mortalis (incl. Cippumomyces gen. nov.)fromatombstone, Cylindrium desperesense from air in a store, Tetracoccosporium pseudoaerium from air sample in house, Toxicocladosporium glendoranum from air in a brick room, Toxicocladosporium losalamitosense from air in a classroom, Valsonectria portsmouthensis from airinmen'slockerroomand Varicosporellopsis americana from sludge in a water reservoir. Vietnam, Entoloma kovalenkoi on rotten wood, Fusarium chuoi inside seed of Musa itinerans , Micropsalliota albofelina on soil in tropical evergreen mixed forest sand Phytophthora docyniae from soil and roots of Docynia indica. Morphological and culture characteristics are supported by DNA barcodes

Biokinetic investigation of the photodynamic activity of new photosensitizers

Results of an in vivo biokinetic investigation of the photodynamic activity of a series of new photosensitizers including a tetraazachlorin derivative (2,3,3α,21α-tetrahydro-2-methyl-3α,8,13,18-tetraphenyl-5,10, 15,20-tetraaza-1H,22H,24H-pyrrolo[3, 4-b]porphine), two difluoroboryl- substituted complexes of 3,3?-diphenylazadiisoindolylmethene {N,N-difluoroboryl-N-[3-(4-t-butylphenyl)-2H-isoindol-1-yl)]-N-[3-(4-t- butylphenyl)-1H-isoindol-1-yliden]amine and N,N-difluoroboryl-1-[3-(4- methoxyphenyl)-2H-isoindol-1-yl)]-N-[3-(4-methoxyphenyl)-1H-isoindol-1-yliden] amine}, and a sulfanyl-substituted phthalocyanine [1,8,15,22-tetrakis(t- butylsulfanyl)-29H, 31H-phthalocyanine] are reported. These compounds exhibit pronounced photodynamic activity in mice bearing solid Ehrlich ascites carcinoma and sarcoma S-37 upon intravenous injection as micellar suspensions in aqueous solutions (4%) of Cremophor EL and Proxanol 268. Acomparison of the tumor growth rate and the time of attaining a critical tumor volume in the test and control groups shows evidence for high photodynamic activity of the new photosensitizers. © 2009 Springer Science+Business Media, Inc

Biokinetic investigation of the photodynamic activity of new photosensitizers

Results of an in vivo biokinetic investigation of the photodynamic activity of a series of new photosensitizers including a tetraazachlorin derivative (2,3,3α,21α-tetrahydro-2-methyl-3α,8,13,18-tetraphenyl-5,10, 15,20-tetraaza-1H,22H,24H-pyrrolo[3, 4-b]porphine), two difluoroboryl- substituted complexes of 3,3?-diphenylazadiisoindolylmethene {N,N-difluoroboryl-N-[3-(4-t-butylphenyl)-2H-isoindol-1-yl)]-N-[3-(4-t- butylphenyl)-1H-isoindol-1-yliden]amine and N,N-difluoroboryl-1-[3-(4- methoxyphenyl)-2H-isoindol-1-yl)]-N-[3-(4-methoxyphenyl)-1H-isoindol-1-yliden] amine}, and a sulfanyl-substituted phthalocyanine [1,8,15,22-tetrakis(t- butylsulfanyl)-29H, 31H-phthalocyanine] are reported. These compounds exhibit pronounced photodynamic activity in mice bearing solid Ehrlich ascites carcinoma and sarcoma S-37 upon intravenous injection as micellar suspensions in aqueous solutions (4%) of Cremophor EL and Proxanol 268. Acomparison of the tumor growth rate and the time of attaining a critical tumor volume in the test and control groups shows evidence for high photodynamic activity of the new photosensitizers. © 2009 Springer Science+Business Media, Inc

Glaucoma "landscape" in Russia, CIS and Eastern European countries: what has changed over 15 years?

A.Yu. Brezhnev1, E.A. Egorov2, V.P. Erichev3, A.V. Kuroedov2,4, P.Ch. Zavadsky5, M. Bozic6, N.N. Voronova7, M.F. Dzhumova8, N.V. Ivanova7, T.A. Imshenetskaya9, T.G. Kamenskikh10, O.I. Lebedev11, L.N. Marchenko8, A.L. Onishchenko12, N.A. Sobyanin13, V.F. Ekgardt14 1Kursk State Medical University, Kursk, Russian Federation 2Pirogov Russian National Research Medical University, Moscow, Russian Federation 3Krasnov Research Institute of Eye Diseases, Moscow, Russian Federation 4P.V. Mandryka Military Clinical Hospital, Moscow, Russian Federation 5LLC "Ophthalmological Center of Karelia", Petrozavodsk, Russian Federation 6University Eye Clinic, University of Belgrade, Belgrade, Serbia 7V.I. Vernadsky Crimean Federal University, Simferopol, Russian Federation 8Belarusian State Medical University, Minsk, Belarus 9Belarusian Medical Academy of Post-Diploma Education, Minsk, Belarus 10V.I. Razumovskiy Saratov State Medical University, Saratov, Russian Federation 11Omsk State Medical University, Omsk, Russian Federation 12Novokuznetsk State Institute for Advanced medical Education — Branch of Russian Medical Academy of Continuous Professional Education, Novokuznetsk, Russian Federation 13F.Kh. Gral City Clinical Hospital No. 2, Perm, Russian Federation 14South Ural State Medical University, Chelyabinsk, Russian Federation Aim: to assess the changes in clinical and epidemiological characteristics, diagnostic and treatment options of primary open-angle glaucoma (POAG) in the Russian Federation and multiple near- and far-abroad countries over the period of 2005–2020. Patients and Methods: the final protocol of this retrospective multi-center research and clinical study included 289 patients with POAG from 7 states (Russia, Belarus, Serbia, Moldova, Kyrgyzstan, Slovakia, and Slovenia). The authors analyzed the methods used for establishing POAP diagnosis, clinical and demographic patient characteristics (gender, age and place of residence), as well as the process of glaucoma development (age of onset, disease duration and stages, intraocular pressure, ocular hypotensive medications, and the used laser and surgical procedures). All patients were divided into four groups depending on the time of making the initial diagnosis: 2004–2005, 2009–2010, 2014–2015, 2019–2020. Results: tonometry with Maklakov and Goldmann tonometers is still considered the gold standard for measuring intraocular pressure (IOP) (95% of cases). The percentage of pneumotonometry increased from 40% in 2005 to 60% in 2020. Approximately a third of clinics are still using electronic tonography as a supplementary method. Static automated perimetry is a basic tool for diagnosis and follow-up of patients with POAG (more than 95% of cases). Manual kinetic perimetry (Foerster's perimetry) is used in less than 10% of cases. Ophthalmoscopy (direct and binocular) was involved in the diagnostic process in all clinics and in all cases. The range of instrumental visualization technologies includes optical coherence tomography (OCT), Heidelberg Retina Tomography (HRT), and scanning laser polarimetry. Currently, OCT is utilized in 90% of clinics. It was found out that in 2005 the standard of initial POAG diagnosis encompassed a set of Maklakov/Goldmann tonometry, ophthalmoscopy and kinetic perimetry. In 2020, this list includes Maklakov/Goldmann tonometry, pneumotonometry as a supplemental tool, static automated perimetry, ophthalmoscopy and OCT. The percentage of newly diagnosed POAG at the early stage has increased twofold over the past 15 years (from 20% in 2005 to 38% in 2020). The mean age of patients at the time of initial POAG diagnosis in 2005 was 62 (52; 67) years, in 2020 — 65 (50; 70) years, respectively (р=0.694). The proportion of prostaglandins in medication therapy increased by 20% over the past 15 years, while the proportion of beta-blockers reduced by the same percentage. The use of cholinomimetic drugs was almost discontinued. The total number of glaucoma laser surgeries has grown, and in the last decade the top priority has been given to selective laser trabeculoplasty, while the share of argon laser trabeculoplasty has decreased by 10%. The rate of primary glaucoma surgeries (trabeculectomy) keeps going down. Conclusion: a gradual and consistent implementation of high-tech diagnostic methods (static automated perimetry and OCT) in the routine practice occurred over 2005–2020. Also, there was a clear trend in more extensive use of objective data. The evolution of pharmaceutical "landscape" in the disease management is associated with an increasing proportion of more effective and safe drugs (prostaglandin analogues) and a diminishing role of beta-blockers as drugs of choice for starting therapy. The share of glaucoma surgeries as a starting strategy of POAG management was running down steadily from 2005 to 2010. Keywords: glaucoma, intraocular pressure, tonometry, perimetry, optical coherence tomography, trabeculectomy. For citation: Brezhnev A.Yu., Egorov E.A., Erichev V.P. et al. Glaucoma "landscape" in Russia, CIS and Eastern European countries: what has changed over 15 years? Russian Journal of Clinical Ophthalmology. 2023;23(2):73–79 (in Russ.). DOI: 10.32364/2311-7729-2023-23-2-73-79.&nbsp; </p