23 research outputs found
Формування нового економічного світогляду в умовах переходу до інформаційного суспільства та інформаційної економіки
Використання моделей для проведення аналізу в системах підтримки прийняття рішень
Інформаційні технології як основа і засіб реалізації інноваційних процесів в сучасній освіті
Впровадження інноваційних підходів, у процесі підготовки науково-педагогічних кадрів
Підвищення ефективності і якості процесу навчання: реалізація можливостей засобів нових інформаційних технологій
Інформаційні комп'ютерні технології в процесі навчання
Сучасні напрями розвитку суспільства. 1.11. The value of the course «Geology with educational practice» in the environmental education of future teachers of geography
The course «Geology with educational practice» forms ideas about the unity of nature and society, develops the ability to assess the load on the geological environment from mining, develops a sense of personal responsibility for the environment
Contemporary Issues of Digital Economy and Society. Higher education in an information society environment
The main characteristic of the information society is that the majority of the population is involved in the production of knowledge. The educational level of the person plays a significant role, as the information society places high demands on both the educational level of each individual and the institute of education as a whole. Higher education is a necessary prerequisite for raising the social status and obtaining the personality of the desired place in the modern society. Thus, the center of social organization, the main social institution is the higher school as a center of production, processing and accumulation of knowledge. It should be noted that in the information society, when information becomes of higher value, and the information culture of a person – the determining factor of professional activity, requirements to the higher education system change, there is a significant increase in its status
Economic cycles and the labor market: opportunities of using crises in the leading indicators system
The paper raises questions about the timeliness of anti-crisis measures taken by the government in Belarus. Particular attention is paid to the possibility of using some indicators of the labor market functioning as predictive indicators of macrodynamics. Within the framework of the problem of cycling, some conceptual issues of diagnosing the phases of the cycle, signs of the onset of a crisis phase in the labor market have been raised. Statistical data of Belarus for 2015 – 2022 were subjected to statistical and econometric analysis
Formation of Speech Activity in Older Preschool Children with Autistic Disorders Formation of Speech Activity in Older Preschool Children with Autistic Disorders
The main condition for personal and mental development of a child is preservation of speech function or, in case of speech pathology, correction and development of all its structural components as a full-fledged means of communication. The purpose of the study is to scientifically substantiate, develop and experimentally test psychological and pedagogical conditions and methods of formation of speech activity in children with autistic disorders of older preschool age. There were highlighted effective methods for speech activity formation: creation and maintenance of a speech environment; constant speech support of a child; teaching a child to express thoughts in any way possible; use of stimulants and incentives in order to increase motivation for speech activity; use of available child’s vocalizations; use of echolalia and a tendency to stereotypical repetition of actions; stimulation of speech activity against the background of emotional recovery; development of speech activity by imitation; activation of passive vocabulary and its gradual translation into active; fostering initiative and desire for self-realization. The indicators of the formation level of speech activity components in EG compared with CG, respectively, are: motivation: high not found, sufficient: + 8.6%, average: + 19%, low: + 14.3%, zero - 41.9%; initiative: high not found, sufficient: + 10.7%, medium: + 13.8%, low: + 9.5%, zero - 34%; content: high: + 4.3%, sufficient: + 17.6%, medium: + 12.9%, low: - 27.3%, zero - 7.5%. The best indicators were achieved by children of the experimental group, which gives reason to assert the effectiveness and feasibility of using the proposed methodology for formation of speech activity in the process of correctional developmental education of children with autistic disorders.</em
Cardiovascular Risk Reduction with Icosapent Ethyl for Hypertriglyceridemia
BACKGROUND
Patients with elevated triglyceride levels are at increased risk for ischemic events. Icosapent
ethyl, a highly purified eicosapentaenoic acid ethyl ester, lowers triglyceride levels, but data
are needed to determine its effects on ischemic events.
METHODS
We performed a multicenter, randomized, double-blind, placebo-controlled trial involving
patients with established cardiovascular disease or with diabetes and other risk factors, who
had been receiving statin therapy and who had a fasting triglyceride level of 135 to 499 mg
per deciliter (1.52 to 5.63 mmol per liter) and a low-density lipoprotein cholesterol level of
41 to 100 mg per deciliter (1.06 to 2.59 mmol per liter). The patients were randomly assigned
to receive 2 g of icosapent ethyl twice daily (total daily dose, 4 g) or placebo. The primary
end point was a composite of cardiovascular death, nonfatal myocardial infarction, nonfatal
stroke, coronary revascularization, or unstable angina. The key secondary end point was a
composite of cardiovascular death, nonfatal myocardial infarction, or nonfatal stroke.
RESULTS
A total of 8179 patients were enrolled (70.7% for secondary prevention of cardiovascular
events) and were followed for a median of 4.9 years. A primary end-point event occurred in
17.2% of the patients in the icosapent ethyl group, as compared with 22.0% of the patients
in the placebo group (hazard ratio, 0.75; 95% confidence interval [CI], 0.68 to 0.83; P<0.001);
the corresponding rates of the key secondary end point were 11.2% and 14.8% (hazard ratio,
0.74; 95% CI, 0.65 to 0.83; P<0.001). The rates of additional ischemic end points, as assessed
according to a prespecified hierarchical schema, were significantly lower in the icosapent
ethyl group than in the placebo group, including the rate of cardiovascular death (4.3% vs.
5.2%; hazard ratio, 0.80; 95% CI, 0.66 to 0.98; P=0.03). A larger percentage of patients in
the icosapent ethyl group than in the placebo group were hospitalized for atrial fibrillation
or flutter (3.1% vs. 2.1%, P=0.004). Serious bleeding events occurred in 2.7% of the patients
in the icosapent ethyl group and in 2.1% in the placebo group (P=0.06).
CONCLUSIONS
Among patients with elevated triglyceride levels despite the use of statins, the risk of ischemic events, including cardiovascular death, was significantly lower among those who received 2 g of icosapent ethyl twice daily than among those who received placebo. (Funded
by Amarin Pharma; REDUCE-IT ClinicalTrials.gov number, NCT01492361