Methyltrimethoxysilane-based elastic aerogels: effects of the supercritical medium on structure-sensitive properties

Effects caused by the type of solvent used for supercritical drying on the properties of methyltrimethoxysilane-based aerogels were studied. All of the aerogel samples studied were found to be hydrophobic and to efficiently adsorb nonpolar organic compounds

New Cases of Scalping from the Burial Grounds of the Pre-Caucasus and the North Caucasus in the Early Iron Age

Several skulls dated to the Early Iron Age discovered in various burial grounds located in the Prikuban and North Caucasus regions are examined in the article. All the skulls are dated to the early Iron Age. The skulls exhibit distinctive signs of scalping. Two of the skulls originate from the Meotian burial ground found in the Starokorsunsky hillfort No. 2, situated near Krasnodar and spanning from the 6th century BC to the 3rd century AD. One of the skulls was excavated from an ancient rural settlement dating to the 2nd centuries BC near the village of Starotitarovskaya in the Krasnodar region. Finally, the remaining skull was unearthed at the Gaston Uota site in Digor Gorge, North Ossetia. This site, concerning the Kobani culture, is dated between the 7th century BC and the 1st half of 4th century BC. The article presents four new instances of scalping originating from Southern Russia. All of the skulls belonged to adult males, and two of them exhibited injuries that appear to have occurred shortly before death. Among the skulls found at the Gaston-Uota burial ground and the settlement near Starotitarovskaya, scalping was executed in the conventional manner, entailing full-scale incisions over the entire hair-covered area. On the other hand, victims buried at the Starokorsunsky hillfort No. 2 displayed evidence of partial scalping, where only the top portion of the cranium vault was scalped, resulting in a limited area of scalp removal. This discrepancy in scalping techniques may reflect distinct cultural traditions associated with this ritualistic practice

Implementation of poultry waste disposal technology for energy and fertilizer production

The developed unit, which implements the technology of separation of raw materials into useful components by thermal destruction, makes it possible to obtain fuel synthesis gas, in which carbon monoxide (CO) and hydrogen (H2) predominate, suitable for use in internal combustion generators for generating electrical energy, as well as saturated ash potassium (K) and phosphorus (P) suitable as a fertilizer in agriculture

Preservation of the immunomodulatory effect of interval hypoxytherapy after coronavirus infection in the long-term period

The new coronavirus infection COVID-19, due to the complex pathogenesis of the disease, systemic impact on organs, the development of complications and persistent disorders after the infection, remains an important medical problem. Every year the number of patients with postcovid syndrome in need of timely and full rehabilitation is increasing. Recently, isolated work began to appear on the use of interval hypoxytherapy for the treatment of patients with coronavirus infection. The purpose of our study was to identify the long-term results of the effect of interval hypoxytherapy on the immunological and coagulation status of patients after suffering coronavirus infection COVID-19. 170 patients aged 45 to 59 years were examined after a moderate coronavirus infection before, after and three months after interval hypoxytherapy. The number of lymphocytes, immunoglobulins A, M, G, E and cytokines (IL-1β, IL-2, IL-4, IL-6, IL-8, IL-10, TNFα) in blood, blood D-dimer, prothrombin time, fibrinogen in blood, antithrombin III, C-reactive was determined protein and ferritin in the blood. The conducted studies revealed changes in immunological reactivity after the coronavirus infection COVID-19, requiring correction. Interval hypoxytherapy had an immunomodulatory effect and led to the normalization of the main immunological parameters, which remained three months after hypoxytherapy: there was a significant (p < 0.05) increase in the number of CD3+T lymphocytes, CD4+T lymphocytes, CD8+T lymphocytes. The improvement in immune status was also evidenced by the normalization of the immunoregulatory index, an increase in the level of immunoglobulins A and G. The decrease in immunoglobulins E in the blood was an indicator of a decrease in the severity of sensitization of the body. The course of hypoxytherapy led to a decrease in the content of pro-inflammatory cytokines: IL-1β, IL-2, IL-6, IL-8, TNFα and an increase in anti-inflammatory cytokines: IL-4 and IL-10 in the blood, which indicated an attenuation of the inflammatory process in the lung tissue and in the body as a whole. Blood ferritin decreased 3 months after hypoxytherapy. As studies have shown, the effect of hypoxytherapy persists for three months after the course of treatment. Thus, interval hypoxytherapy can be recommended for the rehabilitation of patients after a moderate coronavirus infection. A repeated course of hypoxytherapy may be performed three months after the first course of hypoxytherapy

Efficiency of use intraosseus infusion of natrium hydrochlorite 0,03% in the therapy of chronic traumatic osteomyelitis of the lower jaw during the early period

45 patients with traumatic osteomyelitis of lower jaw were divided into two groups. We used standard surgical treatment in the first group (29 patients, 64,4%). Complex therapy of the second group (16 patients, 35,6%) were suppelmented with intraosseous infusion of natrium hypochlorite 0,03%. The results of our investigations allow us to speak about enhancement of efficiency in the treatment of chronoc traumatic osteomyelitis

Intraosseous infusion of medicines with autogenous thrombocytose gel in the therapy of chronic parodontal diseases

63 patients with parodontal diseases were divided into two groups. We used standard flap surgery in the first group (32 patients, 50,8%). Complex therapy of the second group (31 patients, 49,2%) were suppelmented with intraosseous infusion of natrium hypochlorite 0,03%. The results of our investigations allow us to speak about enhancement of efficiency in the complex treatment of parodontal disease

QQˉQ{\bar Q} potential in the Schwinger model on curved space - time

We study the confining and screening aspects of the Schwinger model on curved static backgrounds.Comment: 14 pages, Latex. Typos corrected. Erratum submitte

Aberrant lipid metabolism disrupts calcium homeostasis causing liver endoplasmic reticulum stress in obesity.

The endoplasmic reticulum (ER) is the main site of protein and lipid synthesis, membrane biogenesis, xenobiotic detoxification and cellular calcium storage, and perturbation of ER homeostasis leads to stress and the activation of the unfolded protein response. Chronic activation of ER stress has been shown to have an important role in the development of insulin resistance and diabetes in obesity. However, the mechanisms that lead to chronic ER stress in a metabolic context in general, and in obesity in particular, are not understood. Here we comparatively examined the proteomic and lipidomic landscape of hepatic ER purified from lean and obese mice to explore the mechanisms of chronic ER stress in obesity. We found suppression of protein but stimulation of lipid synthesis in the obese ER without significant alterations in chaperone content. Alterations in ER fatty acid and lipid composition result in the inhibition of sarco/endoplasmic reticulum calcium ATPase (SERCA) activity and ER stress. Correcting the obesity-induced alteration of ER phospholipid composition or hepatic Serca overexpression in vivo both reduced chronic ER stress and improved glucose homeostasis. Hence, we established that abnormal lipid and calcium metabolism are important contributors to hepatic ER stress in obesity