Optimal Resource Deployment in an Infostation-Based Network

This paper considers the problem of finding an optimal deployment of information resources on an InfoStation network in order to minimize the overhead and reduce the time needed to satisfy user requests for resources. The RG-Optimization problem and an approach for its solving are presented as well

Power-line Interference Removal from ECG in Case of Power-line Frequency Variations

The original version of the most successful approach for power-line (PL) interference removal from ECG, called subtraction procedure, is based on linear segment detection in the signal and hardware synchronised analogue-to-digital conversion to cope with the PL frequency variations. However, this is not feasible for battery supplied devices and some computer-aided ECG systems. Recent improvements of the procedure apply software measurement of the frequency variations that allow a re-sampling of the contaminated signal with the rated PL frequency followed by interference removal and back re-sampling for restoration of the original time intervals. This study deals with a more accurate software frequency measurement and introduces a notch filtration as alternative to the procedure when no linear segments are encountered for long time, e.g. in cases of ventricular fibrillation or tachycardia. The result obtained with large PL frequency variations demonstrate very small errors, usually in the range of ± 20 μV for the subtraction procedure and ± 60 μV for the notch filtration, the last values strongly depending on the frequency contents of the QRS complexes

Continuously Tested and Used QRS Detection Algorithm: Free Access to the MATLAB Code

Each ECG analysis begins with the detection of the QRS complex, which is the most distinguishable wave for initial investigation. Long ago we published an algorithm for ventricular beats (VB) detection in single ECG lead. The classification of normal QRS complexes is based on the slope, the amplitude and the width of the ECG waves. Other criteria recognize ventricular ectopic beats (EB) by presence of biphasic beats and separate premature EB from the already detected QRS complexes. The aim of this paper is to place the MATLAB program of our algorithm at disposal to the readers (http://www.biomed.bas.bg/bioautomation/2019/vol_23.1/files/23.1_06.zip) looking forward to more successful ECG investigations

SMILE Maker:a web-based tool for problem solving

This paper focuses on the purposes, theoretical model, and functionality of the SMILE (Solution Mapping Intelligent Learning Environment) Maker--a World Wide Web-based problem-solving tool. From an instructional design point of view, an attempt to establish a balance between constructivism/instructivism, content-treatment interaction/aptitude-treatment interaction, and user locus of control/system locus of control is made. The model behind the SMILE Maker consists of four sub-models (user, content, instructional events, and facilitator), each built from four components. A new concept mapping method that has been developed and experimentally validated is described. Four instructional scenarios--ready-made, tailor-made, self-made, and atelier--are discussed

Induced crystallization of glass-forming melts : Part 1. Heterogeneous nucleation. Effect of noble metal microcrystals on the crystallization of calcium metaphosphate glasses

The possibilities of initiating crystallization in glass-forming melts are analyzed, using experimental evidence, obtained with several model glass-forming systems. In the present Part 1 of the investigation the process of heterogeneous nucleation, catalyzed by insoluble crystallization cores is studied, using a new theoretieal thermodynamie model. The nucleation activity coefficient, Φ, of the aubstrates is described by the adhesion energy, β, at the interface crystallization core/overgrowing crystal. Lattice disregistry is accounted for as an additional correlation factor, influencing the thermodynamie work of adhesion. The crystallization of calcium metaphosphate glass-forming melts, initiated by noble metal microerystals (Ag, Au, Pd, Pt, Rh, Ru, Ir, Os), is studied by differential thermal analysis, optical and scanning electron microseopy. Ir microerystals show highest nucleation activity promoting intensive bulk crystallization in the Ca(PO3)2 systems investigated. The activity of other crystallization cores decreases in the following sequence: Ru > Rh > Os > Pt > Pd > Au > Ag. The above outlined thermodynamic theory of nucleation activity is used to correlate experimental data and to calculate activity coefficients, Φ, in dependence on the properties of the substrates employed. Under tangential stress, applied by pressure in extrusion experiments, the metal microcrystals in the glass samples are stratified in concentric rings with particle density increasing towards the sample surface. Thus a new method of formation of pre-oriented glass-ceramic materials is indicated. In Part 2 of the investigation the effect of soluble oxide additives on nucleation and crystallization in glass-forming melts is considered

Aloenzimna genetichna harakteristika na pchelni semeystva Apis mellifera (Hymenoptera: Apidae) ot Bulgaria s razlichno higienno povedenie

The genetic variability in 25 honey bee colonies from different regions of Bulgaria with different hygienic behaviour (highly hygienic, hygienic and non-hygienic) has been studied. Alloenzyme analysis of two systems (MDH-1 and Est-3) corresponding to 2 loci was used in order to characterize the colony polymorphism. Totally 1,150 worker bees were included in this investigation. MDH-1 locus was found to be polymorphic in all of the studied colonies, having two alleles – MDH-165 and MDH-1100. The Est-3 locus was fixed in ten of the investigated colonies. Polymorphism with total presence of four alleles of this locus (Est-380, Est-388, Est-3100 and Est-3118) was found in the other studied colonies. The calculated polymorphism was 50% in the non-hygienic and 100% in the highly hygienic and hygienic colonies. The observed and expected heterozygosities (Ho and He) ranged from 0.296 to 0.354 and from 0.28 to 0.332 in non-hygienic and highly hygienic groups, respectively. The calculated mean observed and expected heterozygosities were 0.32 and 0.307, respectively. The calculated Fst and Nm levels demonstrated lower differentiation between highly hygienic and hygienic colonies and higher differentiation between highly hygienic and non-hygienic colonies. Dissimilarities between levels of polymorphism, heterozygosity, Fst, Nm and allele frequencies in the studied groups of colonies with different hygienic behaviour were found and discussed. The results of the present study provide new information concerning relations between hygienic behaviour and alloenzyme characteristics which could be used for future selection with honey bees in Bulgaria.Obekt na nastoyashtoto izsledvane e genetichnata izmenchivost, ustanovena pri rabota s 25 pchelni semeystva ot razlichni rayoni na Bulgaria s razlichno higienno povedenie (Visoko higienichni, higienichni i ne-higiennichni). Izyaveniyat polimorfizam e harakteriziran na bazata na aloenzimen analiz po dve sistemi (MDH-1 i Est-3), saotvetstvashti na dva polimorfni lokusa. Obshto 1150 pcheli rabotnichki sa vklyucheni v izsledvaneto. Ustanoveno e, che MDH-1 lokusat e polimorfen vav vsichki izsledvani pchelni semeystva i e predstaven ot dva alela - MDH-165 i MDH-1100. Est-3 lokusat e fiksiran v deset ot izsledvanite kolonii. Po tozi lokus e konstatiran polimorfizam s prisastvie obshto na chetiri alelni varianti (Est-380, Est-388, Est-3100 i Est-3118) za genofonda na ostanalite pchelni semeystva. Izchisleniyat polimorfizam e mezhdu 50% i 100%. Ustanovenata i ochakvanata heterozigotnost (Ho i He) varira saotvetno ot 0.296 do 0.354 i 0.28 ot 0.332 pri ne-higienichnite i visoko higienichnite grupi. Izchislenite sredna nablyudavana i ochakvana heterozigotnosti sa saotvetno 0.32 i 0.307. Izchislenite niva na Fst i Nm pokazvat po-niska diferentsiatsia mezhdu visoko higienichnite i higienichnite semeystva i visoka diferentsiatsia mezhdu visoko higienichnite i ne-higienichnite semeystva. Konstatirani i obsadeni sa razlichia mezhdu nivata na polimorfizam, heterozigotnost, Fst, Nm i alelnite chestoti v izsledvanite grupi pchelni semeystva s razlichno higienno povedenie. Rezultatite ot nastoyashtoto prouchvane davat nova informatsia otnosno zavisimostta mezhdu nivata na higienno povedenie i aloenzimnite harakteristiki, koito biha mogli da se izpolzvat v badeshti deynosti po selektsia na medonosnite pcheli v Bulgaria

Митоинхибиращ и кластогенен ефект на води от антропогенно повлияни зони

The present study aims to analyse the effect of waters, anthropogenically influenced by various pollutants, on the mitotic division and chromosomal apparatus of cells by establishing their potential mitoinhibitory and clastogenic effect. The cytotoxic and mutagenic effect of contaminated water was examined by the application of the Allium cepa test system. Mitotic depression has been established for samples with available anthropogenic contamination. Microscopic analysis showed an increased incidence of chromosomal aberrations in the test samples compared to the control, resulting from the genotoxic effect available. Chromosomal abnormalities of the type of lagging and ‘vagrant’ chromosomes, chromosomal fragments, anaphase and telophase bridges, micronuclei, as well as deviations from normal cell division such as K-mitoses and asynchronous mitoses have been observed. The analysis of the spectrum of chromosomal aberrations shows some differences in the frequency of occurrence of the different types of disorders, which reflects the specificity of the genotoxic effect of the water samples from the surveyed areas.Настоящото проучване има за цел да анализира влиянието на антропогенно повлияни от различни замърсители води върху митотичното делене и хромозомния апарат на клетките чрез установяване на потенциалния им митоинхибиращ и кластогенен ефект Чрез прилагане на Allium cepa тест-системата е проучено цитотоксичното и мутагенното действие на замърсените води. Констатирана е митотична депресия за пробите с налично антропогенно замърсяване. Микроскопският анализ показва увеличена честота на хромозомните аберации в опитните проби в сравнение с контролната, което е резултат от наличен генотоксичен ефект. Констатирани са хромозомни аномалии от типа на изоставащи и „скитащи” хромозоми, хромозомни фрагменти, анафазни и телофазни мостове, микроядра, както и отклонения от нормалното клетъчно делене като К-митози и асинхронни митози. Анализът на спектъра на хромозомните аберации показва известни различия в честотата на срещане на отделните типове нарушения, което отразява спецификата на генотоксичното действие на водните проби от проучваните зони