374 research outputs found

    Les apports de la langue d’enseignement au français langue étrangère dans les programmes scolaires algériens de la 5ème année primaire (2ème génération)

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    Dans cet article, nous posons la problématique de l’élaboration des compétences transversales langagières dans les programmes scolaires algériens de la cinquième année primaire de la langue arabe et du français (deuxième génération). Les deux composantes linguistiques constituent un des éléments fondamentaux du soubassement cognitif à dominante langagière dans le dispositif d’enseignement /apprentissage. Les grilles d’analyse inspirées de la taxonomie de Bloom concernant les catégories cognitives pour l’étude des composantes des compétences terminales ont permis de rendre manifeste les dysfonctionnements dans les opérations de transfert cognitif entre les deux langues

    COMPRÉHENSION DE TEXTES ARGUMENTATIFS EN CLASSE DE QUATRIÈME ANNÉE MOYENNE : TRANSFERT DE LA LANGUE D’ENSEIGNEMENT VERS LE FLE / ARGUMENTATIVE TEXTS COMPREHENSION IN FOURTH YEAR MIDDLE SCHOOL CLASS : LANGUAGE TEACHING TRANSFER TOWARD FRENCH AS A FOREIGN LANGUAGE

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    Cette recherche pose la problématique du transfert des apprentissages de la langue arabe vers la langue française en compréhension de textes argumentatifs signalés par des marqueurs d’intégration linéaire chez les apprenants de la quatrième année moyenne. Notre expérimentation en classe a montré que le fait de suivre un enseignement en langue arabe axé sur ce type de texte et d’en prendre conscience, semble fournir aux apprenants du groupe expérimental des outils nouveaux de régulation de la lecture (compréhension), assurant un certain niveau d’efficacité et de transfert qui font défaut aux apprenants du groupe-contrôle

    MANUELS SCOLAIRES ALGÉRIENS DE LANGUES EN CINQUIÈME ANNÉE PRIMAIRE ET PRÉPARATION À LA PRODUCTION ÉCRITE : TRANSFERT DE L’ARABE VERS LE FRANÇAIS / ALGERIAN FIFT GRADE PRIMARY SCHOOL LANGUAGE TEXTBOOKS AND PREPARATION FOR WRITTEN PRODUCTION : THE TRANSFER FROM ARABIC TO FRENCH

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    The current study endeavours to submit for analysis the conception and articulation modes of the activity/process of preparation for the written production in the Algerian Arabic and French language textbooks of the fifth year of the primary education. In fact, the two linguistic components constitute, in the Algerian educational system, one of the fundamental elements of the predominantly linguistic cognitive foundation. Bloom’s taxonomy regarding cognitive categories for the study of this activity/process has made it possible to highlight dysfunctions in cognitive transfer opérations between the two languages

    Novel Area-Efficient and Flexible Architectures for Optimal Ate Pairing on FPGA

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    While FPGA is a suitable platform for implementing cryptographic algorithms, there are several challenges associated with implementing Optimal Ate pairing on FPGA, such as security, limited computing resources, and high power consumption. To overcome these issues, this study introduces three approaches that can execute the optimal Ate pairing on Barreto-Naehrig curves using Jacobean coordinates with the goal of reaching 128-bit security on the Genesys board. The first approach is a pure software implementation utilizing the MicroBlaze processor. The second involves a combination of software and hardware, with key operations in FpF_{p} and Fp2F_{p^{2}} being transformed into IP cores for the MicroBlaze. The third approach builds on the second by incorporating parallelism to improve the pairing process. The utilization of multiple MicroBlaze processors within a single system offers both versatility and parallelism to speed up pairing calculations. A variety of methods and parameters are used to optimize the pairing computation, including Montgomery modular multiplication, the Karatsuba method, Jacobean coordinates, the Complex squaring method, sparse multiplication, squaring in Gϕ6Fp12G_{\phi 6}F_{p^{12}}, and the addition chain method. The proposed systems are designed to efficiently utilize limited resources in restricted environments, while still completing tasks in a timely manner.Comment: 13 pages, 8 figures, and 5 table

    Constructing Singapore : Elitism, Ethnicity and the Nation-Building Project, Michael D. Barr & Zlatko Skrbis

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    Michael Barr, seul ou en collaboration, est depuis une décennie l’un des auteurs les plus prolifiques et les plus reconnus sur la structuration politique et sociologique du Singapour contemporain. Longtemps attaché à l’université du Queensland (Brisbane), aujourd’hui à Flinders (Adelaide), il est assez représentatif de la nouvelle génération (singapourienne aussi bien qu’étrangère) des spécialistes de la cité-état : fermement critique, et parfois même hyper-critique, elle n’en reconnaît pas m..

    Zootehnički, bakteriološki i histometrijski učinci kombinacije veziva za mikotoksin-sredstva za zakiseljavanje u tovnih pilića

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    Mycotoxins are present in food and cannot be eliminated even by using modern technological processes in food manufacture; they can cause pathologies and economic losses in the poultry industry. To combat their effects, this study aimed to test the incorporation of a mycotoxin binder (MICOTEC 0.1%) associated with an acidifier (TECAVIAR 0.1%), both marketed in Algeria, in the feed distributed to broilers. During this study, a beneficial effect was found in subjects consuming the supplemented food compared to the control subjects. In addition to the significant decrease in mortality (51.47%), test subjects showed an average weight of 3308.1 g, which was significantly higher than control subjects (2876.25 g). The data revealed a significant reduction in the number of total and faecal coliforms, with prevalence ranging from 3.1 to 36.5% vs 63.2 to 96.9% for the control group. An increase in the length of the small intestine (24.13 cm), increase in the weight of the Fabricius bursa (FB; 1.25 g), weight of the gizzard (10.25 g) and finally an increase in the weight of the wishbone (153.87 g) were recorded in the test subjects. The results indicate that the association of mycotoxin binder-acidifier in broiler chickens can improve growth performance. Further experiments are required to confirm more effects (with different doses, different strains, and other organs).Mikotoksini su prisutni u hrani i nije ih moguće eliminirati niti uporabom modernih tehnoloških procesa u prehrambenoj industriji; mogu prouzročitit patologije i ekonomske gubitke u peradarskoj industriji. Za borbu protiv njihovih učinaka, odlučili smo ispitati alternativne načine inkorporiranjem veziva za mikotoksin (MICOTEC 0,1 %) u kombinaciji sa sredstvom za zakiseljavanje (TECAVIAR 0,1 %), koji se prodaju na tržištu u Alžiru, u hranu koja se daje tovnim pilićima. Tijekom ove studije otkrili smo vrlo blagotvoran učinak na subjekte koji su konzumirali hranu s dodacima u usporedbi s kontrolnim subjektima. U stvari, zamijetili smo, uz značajno smanjenje mortaliteta (51,47 %), prosječnu masu od 3308,10 g, što je značajno više od one kontrolnih subjekata (2876,25 g). Uz to, podatci su otkrili značajno smanjenje broja ukupnih fekalnih koliforma, s prevalencijom u rasponu od 3,07 % do 36,50 % u usporedbi s 63,22 % do 96,93 % za kontrolnu skupinu. Zamijetili smo i povećanje duljine tankog crijeva s 24,13 cm, povećanje mase Fabriciusove burze (FB) s vrijednošću od 1,25 g, mase želudca (10,25 g) te povećanje mase jadca (153,87 g). Na temelju ovih podataka, moguće je rabiti kombinaciju veziva mikotoksina i sredstva za zakiseljavanje u tovnih pilića za poboljšanje rasta. Potrebni su dodatni eksperimenti za potvrđivanje više učinaka (s različitim dozama, različitim sojevima i drugim organima)

    Učinak dodatka hrani (zakiseljivača i sredstva za vezivanje toksina) u proizvodnji mlijeka u mliječnih krava

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    Dairy cow feeding plays an important role in milk production. The present study was conducted to evaluate the effect of a feed additive (association of acidifier and mycotoxin binder) on milk production in dairy cattle. For this purpose, 22 cows belonging to three breeds (Montbeliard, Holstein, and Flekveih) were used. The cows were divided into two groups; a control group with seven cows and an experimental group with 15 animals. The results showed that the additive had a positive effect on milk production (23.14±5.87 litres for the experimental group vs 18.00±6.90 litres for the control). The additive also had a good effect on the percentage of sub-clinical mastitis: the Californian Mastitis Test (CMT) carried out at monthly intervals showed a clear improvement in the udder health of females in the experiment with 13 positive samples in the first test for nine cows (with four affected teats) and 10 positive samples for the second test in three cows (with three affected teats). Moreover, statistical tests revealed a significant difference in the mean fat content (35 g/L vs 23.86 g/L, respectively) while the average Faeces Consistency Score and Dornic acidity was lower in the experimental group compared to the control (2.23 vs 3.21 and 13.83 vs 16.14, respectively). These results show the importance of incorporating the feed additive into the diet of dairy cows and the need to implement an extension programme and zootechnical supervision of all actors in the sector to ensure the quality of milk production and the performance of dairy cows.Hranidba mliječnih krava je vrlo važna u njihovoj proizvodnji. Ova studija je provedena za procjenu učinka dodatka hrani (kombinacije zakiseljivača i sredstva za vezivanje mikotoksina) na proizvodnju mlijeka u mliječnih krava. U tu su svrhu praćeme 22 krave: 3 pasmine (montbeliard, holstein i flekveih). Krave su podijeljene u 2 skupine: kontrolnu skupinu sa 7 krava i eksperimentalnu skupinu s 15 životinja. Dobiveni rezultati pokazali su da organska kiselina ima pozitivan učinak na proizvodnju mlijeka (23,14±5,87 litara za eksperimentalnu skupinu u usporedbi s 18,00±6,90 litara za kontrolnu skupinu). Uz to, aditiv je imao i pozitivan učinak na postotak subkliničkog mastitisa. Kalifornijski mastitis test (CMT) proveden u razmaku od 1 mjeseca za životinje pokazao je jasno poboljšanje zdravlja vimena krava podvrgnutih istraživanju s 13 pozitivnih uzoraka u prvom testu za 9 krava (s 4 zahvaćene sise) i 10 drugih pozitivnih uzoraka za drugi test u 3 krave (s 3 zahvaćene sise). Statistički testovi su otkrili značajnu razliku između prosječnog udjela masnoća (35 g/L u usporedbi s 23,86 g/L) dok je prosječno bodovanje konzistencije izmeta i kiselost po Dornicu bilo niže u istoj skupini u usporedbi s kontrolnom skupinom (2,23 u usporedbi s 3,21 i 13,83 u usporedbi s 16,14). Podatci su pokazali važnost i potrebu dodatka hrani u hranidbu mliječnih krava i potrebu za provedbom programa proširenja i zootehničkog nadzora svih aktera u sektoru da bi se osigurala kvaliteta proizvodnje mlijeka i učinkovitost mliječnih krava

    Učinak uporabe adsorbensa toksina na učinkovitost rasta tovnih pilića

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    Raw material mixtures in compound feeds may increase the risk of contamination with different mycotoxins, and their intake can lead to interactive toxic effects. As a result, there is a growing awareness of the risks posed to human and animal health by the presence of toxins produced by fungi in food and diet. The aim of this study is to assess the impact of the use of a mycotoxin binder (Micotec) on zootechnical performance in broilers. For this purpose, 3000 day-old chicks of the Arbor acres strain originating from the same hatchery were weighed and distributed equally into six groups [one control (C) and five experimental (Exp), as five repetitions receiving the mycotoxin binder Micotec at a dose of 0.1 kg]. All subjects (control and experimental groups) were fed a standard staple food suitable for each phase of rearing. The results showed significant differences between the experimental groups and the control one. The best zootechnical performances were recorded in experimental groups receiving the mycotoxin binder, compared to the control. The average weight in the finishing phase for the experimental groups was 3083.6 ± 140.7 g/subject, which was higher than the control group (2800 g/subject) (P<0.05). The consumption index was 1.62 ± 0.08% in the experimental groups, which was 1.84% higher than in chicks of the control group, positively impacting the profitability of breeding. In addition, a lower mortality rate was recorded in the experimental groups than the control (3.01 ± 0.08% vs 7.78%). According to these results, Micotec appears to be a promising additive in improving the zootechnical performance of broilers by adsorbing several types of mycotoxins and reducing their toxic power to ensure safe feed for animals and minimise economic losses caused by these contaminants.Mješavina različitih sirovina u krmnim smjesama može povećati rizik od kontaminacije s nekoliko mikotoksina, a njihov unos može dovesti do interaktivnih toksičnih učinaka. Kao rezultat, zbog prisutnosti toksina koje proizvode gljivice u hrani i prehrani postoji sve veća svijest o rizicima za zdravlje ljudi i životinja. Cilj je ove studije bio procijeniti učinak uporabe sredstva za vezivanje mikotoksina (Micotec) na zootehničku učinkovitost u tovnih pilića. U tu je svrhu, tri tisuće (3000) pilića soja Arbor acres starih jedan dan iz iste valionice izvagano je i homogeno podijeljeno u 6 skupina (1 kontrolna (C) i 5 eksperimentalnih (Exp) koje su uključivale 5 ponavljanja primanja sredstva za vezivanje mikotoksina Micotec) u dozi od 0,1 kg. Svi pilići i iz kontrole i iz eksperimentalnih skupina hranjeni su standardnom osnovnom hranom prikladnom za svaku fazu uzgoja. Dobiveni rezultati pokazali su značajne razlike između eksperimentalnih skupina i kontrolne skupine. Naime, bolja zootehnička učinkovitost u usporedbi s kontrolnom skupinom zabilježena je u eksperimentalnim skupinama koje su primale sredstvo za vezivanje mikotoksina. Prosječna masa u završnoj fazi za eksperimentalne skupine bila je 3083,6 ± 140,65 g / piliću što je više u usporedbi s kontrolnom skupinom (2800 g / piliću) (P<0,05). Osim toga, indeks potrošnje bio je 1,62 % ± 0,078 u eksperimentalnim skupinama što je bolje u usporedbi s onim zabilježenim u pilića u kontrolnoj skupini (1,84 %), a to pokazuje pozitivan učinak na profitabilnost uzgoja; uz to je i niska stopa smrtnosti zabilježena u eksperimentalnim skupinama (3,01 % ± 0,078 u usporedbi sa 7,78 % za kontrolnu skupinu). Prema ovim rezultatima, Micotec se čini kao obećavajući aditiv u poboljšanju zootehničke učinkovitosti tovnih pilića apsorpcijom nekoliko vrsta mikotoksina i smanjenjem njihove toksičnosti osiguravajući sigurnu hranu za životinje, a koja smanjuje i ekonomske gubitke prouzročene tim mikotoksinima

    O-GlcNAcylation-Inducing Treatments Inhibit Estrogen Receptor α Expression and Confer Resistance to 4-OH-Tamoxifen in Human Breast Cancer-Derived MCF-7 Cells.

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    PLoS OneInternational audienceO-GlcNAcylation (addition of N-acetyl-glucosamine on serine or threonine residues) is a post-translational modification that regulates stability, activity or localization of cytosolic and nuclear proteins. O-linked N-acetylgluocosmaine transferase (OGT) uses UDP-GlcNAc, produced in the hexosamine biosynthetic pathway to O-GlcNacylate proteins. Removal of O-GlcNAc from proteins is catalyzed by the β-N-Acetylglucosaminidase (OGA). Recent evidences suggest that O-GlcNAcylation may affect the growth of cancer cells. However, the consequences of O-GlcNAcylation on anti-cancer therapy have not been evaluated. In this work, we studied the effects of O-GlcNAcylation on tamoxifen-induced cell death in the breast cancer-derived MCF-7 cells. Treatments that increase O-GlcNAcylation (PUGNAc and/or glucosoamine) protected MCF-7 cells from death induced by tamoxifen. In contrast, inhibition of OGT expression by siRNA potentiated the effect of tamoxifen on cell death. Since the PI-3 kinase/Akt pathway is a major regulator of cell survival, we used BRET to evaluate the effect of PUGNAc+glucosamine on PIP3 production. We observed that these treatments stimulated PIP3 production in MCF-7 cells. This effect was associated with an increase in Akt phosphorylation. However, the PI-3 kinase inhibitor LY294002, which abolished the effect of PUGNAc+glucosamine on Akt phosphorylation, did not impair the protective effects of PUGNAc+glucosamine against tamoxifen-induced cell death. These results suggest that the protective effects of O-GlcNAcylation are independent of the PI-3 kinase/Akt pathway. As tamoxifen sensitivity depends on the estrogen receptor (ERα) expression level, we evaluated the effect of PUGNAc+glucosamine on the expression of this receptor. We observed that O-GlcNAcylation-inducing treatment significantly reduced the expression of ERα mRNA and protein, suggesting a potential mechanism for the decreased tamoxifen sensitivity induced by these treatments. Therefore, our results suggest that inhibition of O-GlcNAcylation may constitute an interesting approach to improve the sensitivity of breast cancer to anti-estrogen therapy

    Prevalencija i identifikacija Corynebacterium pseudotuberculosis u zaklanih ovaca u središnjoj regiji Alžira

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    Caseous lymphadenitis, also called abscess disease, is an infectious, cosmopolitan disease. The causative agent is a Gram-positive bacillus, Corynebacterium pseudotuberculosis that is resistant to antibiotic treatment. Humans become infected with this bacillus, but the disease is considered a neglected zoonosis. The objective of this study was to estimate the prevalence and to identify Corynebacterium pseudotuberculosis in sheep slaughtered in central Algeria. For this purpose, 897 animals were examined and samples (pus) were taken from 12 sheep with abscesses to perform bacteriological study. Sex, age, and location of the abscess were noted. The results obtained showed an overall prevalence of 1.33%. The highest rate (50%) was observed in animals aged between 8 months and 1 year. Males were more affected by abscesses (66.7%) than females (33.3%). As for localisation, 41% of abscesses were found in the pulmonary lymph nodes and 25% in the submandibular region. Infection by Corynebacterium was estimated at a rate of 25%, lower than that obtained for Staphylococcus (41.7%). Regarding the zoonotic nature of the disease, the bacteria’s ability to survive in the external environment, and the high risk of contamination, management measures should be implemented for better disease control and prevention.Kazeozni limfadenitis (CL), zvan i pseudotuberkuloza, zarazna je kozmopolitska bolest. Uzročnik je gram-pozitivna bakterija, Corynebacterium pseudotuberculosis otporna na liječenje antibioticima. Ljudi se mogu zaraziti ovom bakterijom, ali se bolest smatra zanemarenom zoonozom. Cilj ove studije bio je procijeniti prevalenciju i identificirati Corynebacterium pseudotuberculosis u ovaca zaklanih u središnjoj regiji Alžira. U tu svrhu, 897 životinja je ispitano i uzorci (gnoj) su izuzeti od 12 ovaca s apscesima za potrebe bakteriološke studije. Zabilježeni su spol, dob i lokacija apscesa. Dobiveni rezultati pokazali su sveukupnu prevalenciju od 1,33 %. Najveća stopa (50 %) zamijećena je u životinja u dobi između 8 mjeseci i 1 godine. Mužjaci su imali više apscesa (66,7 %) od ženki (33,3 %). Što se tiče lokalizacije, 41 % apscesa pronađeno je u plućnim limfnim čvorovima, a 25 % u submandibularnom području. Infekcija bakterijom Corynebacterium procijenjena je u stopi od 25 %, što je manje od stope dobivene za Staphylococcus (41,7 %). U konačnici, s obzirom na zoonotsku prirodu CL-a, preživljavanje bakterije u vanjskom okruženju te veliki rizik od zaraze, potrebno je implementirati mjere upravljanja za bolju kontrolu i prevenciju bolesti
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