258 research outputs found

    High-resolution distributed sampling of bandlimited fields with low-precision sensors

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    The problem of sampling a discrete-time sequence of spatially bandlimited fields with a bounded dynamic range, in a distributed, communication-constrained, processing environment is addressed. A central unit, having access to the data gathered by a dense network of fixed-precision sensors, operating under stringent inter-node communication constraints, is required to reconstruct the field snapshots to maximum accuracy. Both deterministic and stochastic field models are considered. For stochastic fields, results are established in the almost-sure sense. The feasibility of having a flexible tradeoff between the oversampling rate (sensor density) and the analog-to-digital converter (ADC) precision, while achieving an exponential accuracy in the number of bits per Nyquist-interval per snapshot is demonstrated. This exposes an underlying ``conservation of bits'' principle: the bit-budget per Nyquist-interval per snapshot (the rate) can be distributed along the amplitude axis (sensor-precision) and space (sensor density) in an almost arbitrary discrete-valued manner, while retaining the same (exponential) distortion-rate characteristics. Achievable information scaling laws for field reconstruction over a bounded region are also derived: With N one-bit sensors per Nyquist-interval, Θ(logN)\Theta(\log N) Nyquist-intervals, and total network bitrate Rnet=Θ((logN)2)R_{net} = \Theta((\log N)^2) (per-sensor bitrate Θ((logN)/N)\Theta((\log N)/N)), the maximum pointwise distortion goes to zero as D=O((logN)2/N)D = O((\log N)^2/N) or D=O(Rnet2βRnet)D = O(R_{net} 2^{-\beta \sqrt{R_{net}}}). This is shown to be possible with only nearest-neighbor communication, distributed coding, and appropriate interpolation algorithms. For a fixed, nonzero target distortion, the number of fixed-precision sensors and the network rate needed is always finite.Comment: 17 pages, 6 figures; paper withdrawn from IEEE Transactions on Signal Processing and re-submitted to the IEEE Transactions on Information Theor

    Study of ground state phases for spin-1/2 Falicov-Kimball model on a triangular lattice

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    The spin-dependent Falicov-Kimball model (FKM) is studied on a triangular lattice using numerical diagonalization technique and Monte-Carlo simulation algorithm. Magnetic properties have been explored for different values of parameters: on-site Coulomb correlation UU, exchange interaction JJ and filling of electrons. We have found that the ground state configurations exhibit long range Ne\`el order, ferromagnetism or a mixture of both as JJ is varied. The magnetic moments of itinerant (dd) and localized (ff) electrons are also studied. For the one-fourth filling case we found no magnetic moment from dd- and ff-electrons for UU less than a critical value.Comment: 6 pages, 8 figure

    PYRIMIDINES AS POTENT CYTOTOXIC AND ANTI-INFLAMMATORY AGENTS

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    Objective: Many derivatives of pyrimidine are known for the broad-spectrum biological activities such as antimicrobial, antitumor, antibacterial, antitubercular, anti-inflammatory, and cytotoxic activity. Chalcones with an enone group show potent pharmacological activities such as antiinflammatory, antibacterial, antifungal, and antimalarial activity. A series of pyrimidines from chalcones have been synthesized and screened for anti-inflammatory and cytotoxic activity studies.Methods: Chalcones [1-(4-nitrophenyl)-3-substituted-phenylprop-2-en-1-one] were synthesized from various substituted aldehydes with 4-nitroacetophenone and cyclized with urea and glacial acetic acid to give pyrimidine derivatives [4-(4-nitrophenyl)-6-substituted-phenylpyrimidin-2-ol].Results: Anti-inflammatory and cytotoxic activity studies revealed that some of the synthesized compounds have shown significant activity.Conclusion: The observed results proved that pyrimidines are found to be interesting lead molecules for the synthesis of anti-inflammatory and cytotoxic agent

    SYNTHESIS AND ANTI-INFLAMMATORY ACTIVITY OF SOME NOVEL 1,5 BENZODIAZEPINE DERIVATIVES

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    ABSTRACTObjective: The objective of the study is to synthesize some novel 1,5-benzodiazepine derivatives from chalcones. The structures of the newlysynthesized compounds were characterized by elemental analysis, infrared, H nuclear magnetic resonance, and mass spectroscopic studies. All titledcompounds were screened for their anti-inflammatory activity.1Methods: In this study, a series of novel 2-(substituted phenyl)-3-styryl-2,3-dihydro-1H-benzo [b] [1,4] diazepine (1-12) has been synthesizedfrom 1,5-(disubstituted phenyl)-2,4-pentadien-1-one (1a-12a). 1,5-(disubstituted phenyl)-2,4-pentadien-1-one was prepared by condensingcinnamaldehyde with various aromatic ketones in the presence of 20% NaOH as base. Different 1,5-(disubstituted phenyl)-2,4-pentadien-1-one oncyclisation with o-phenylene diamine in the presence of NaOH as base resulted in 2-(substituted phenyl)-3-styryl-2,3-dihydro-1H-benzo [b] [1,4]diazepine derivatives. The final synthesized benzodiazepine derivatives were screened for their anti-inflammatory activity using carrageenaninducedratpawedema method.Results: The compounds 4, 5, 7, 9, 10, 11, and 12 containing 4-nitrophenyl, 4-chlorophenyl, 3-nitro phenyl, 4-fluorophenyl, 4-bromophenyl, and3-chlorophenyl benzodiazepine derivatives exhibited significant anti-inflammatory activity compared with the standard diclofenac sodium Thepresence of electron withdrawing groups such as nitro, chloro, fluoro, and bromo resulted in increased anti-inflammatory activity.Conclusion: This study reports the successful synthesis of 1,5-benzodiazepine derivatives with moderate yields and most of the synthesizedcompounds showed significant anti-inflammatory activity.Keywords: Chalcones, 1,5-benzodiazepines, Anti-inflammatory activity

    A Comparative study of muscular strength among boxers and wrestlers

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    In the present study, an attempt has been made to compare Muscular Strength component among Boxers and Wrestlers. The study was carried out on 300 male players in the age group of 17-28 years, from Boxers (N=150) and Wrestlers (N=150). The subjects were under graduate students of Diff. Colleges from Haryana. The data was collected by use of AAHPER Youth Fitness Test. The data was analyzed and compared with the help of statistical procedures in which arithmetic mean, standard deviation (S.D.), t-test were employed. Boxing male players and Wrestling male players Muscular Strength was found no significantly Difference. Keywords- Muscular Strength, Wrestlers, Boxers. &nbsp

    PYRAZOLINES AS POTENT ANTITUBERCULAR AND CYTOTOXIC AGENTS

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    Objective: Pyrazolines are known to exhibit different biological and pharmacological properties such as anticancer, antibacterial, antifungal and antitubercular activities. Chalcones with an enone group between two aromatic rings exhibit remarkable pharmacological activities such as antiinflammatory, antibacterial, antitumor, antifungal, and antimalarial activity. A series of pyrazolines from chalcones have been synthesized and evaluated for antitubercular and cytotoxic activity studies.Methods: Chalcones [3-substituted phenyl-1-(p-tolyl)prop-2-en-1-one] were synthesized from various substituted aldehydes and 4-methyl acetophenone and cyclized into pyrazolines [5-substituted phenyl-3-(p-tolyl)-4,5-dihydro-1H-pyrazole] using hydrazine hydrate. Antitubercular and cytotoxic activity studies were carried out.Results: Antitubercular and cytotoxic activity studies of synthesized pyrazoline revealed that some compounds have showed promising activity.Conclusion: The observed results proved that pyrazolines are found to be interesting lead molecules for further synthesis as antitubercular and cytotoxic agents

    IMPACT OF PERCEIVED STRESS ON GENERAL HEALTH: A STUDY ON ENGINEERING STUDENTS

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    In today’s competitive world, individuals have to undergo varied stressful situations right from their adolescence to old age. Students who are pursuing their higher education cannot keep themselves away from the inevitable and inescapable wrath of anxiety and stress, resultant from the demands of the present education system. Thus, the present research examines the relationship between perceived stress and general health of engineering students. The Perceived Stress Scale (PSS; Cohen et al., 1988), and the General Health Questionnaire (GHQ; Goldberg, 1981) were administered on 139 engineering students from two reputed engineering institutions in India, one in Bangalore and the other in Raipur, aged 18 to 22 years. Data analysis techniques such as Pearson correlation coefficients were used to identify relationships between perceived stress and general health. General health consists of two factors: sense of accomplishment (SOA) and botheration-free existence (BFE). Results showed that both SOA and BFE are negatively correlated with stress. As perceived stress increases, student’s sense of accomplishment (i.e. their zeal to make an impact) decreases, but this relationship was found to be non-significant. Again, stress was negatively correlated with BFE and this time a significant relationship was found, i.e. as stress increases it induces worry and botheration in students. Further, this means that in these institutions, students’ perceived stress induces negative health conditions in them. However, students who can adapt better coping mechanism would have a better state of general health

    Progressive rise of c fos expression from premalignant to malignant lesions of oral cavity

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    Objectives: Oral cancer is a worldwide phenomenon. It is thought to develop in a number of premalignant lesions. Protooncogene c fos is a known transformer of premalignant to malignant lesions. However, its role in oral carcinogenesis is not yet known. Study design: A total of 130 cases were studied comprising of premalignant lesions (n=50), squamous cell carcinoma (n=50) and controls (n=30). c fos expression was studied by immunohistochemistry. Results: Premalignant lesions of oral cavity occurred at a lower age group (mean 39.2 years) compared to squamous cell carcinoma (mean 51.8 years), p <0.001. Mean c fos percentage positivity in squamous cell carcinomas (SCC), premalignant lesions and controls was 44.5±36.9%, 11.4±18.8% and 1.23±2.6% respectively, the differences were highly significant (p<0.001). c fos positivity also increased from mild (10.85±14.23%) to moderate dysplasia (19.64 ±26.05%). Conclusions: The serially increasing c fos expression from normal mucosa to premalignant lesions to SCC and in dysplasias suggests that it could be an early gene to get activated and form transcription factor activator protein ?1(AP-1)

    BELL'S PALSY AMONG INFANTS - OUR EXPERIENCES IN A TERTIARY CARE HOSPITAL OF EASTERN INDIA

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    Objectiv:The most common etiology of unilateral facial palsy is Bell's palsy, also called as idiopathic facial palsy. Bell's palsy in infant is rare and an uncommon clinical entity and often taken as pediatric emergency by parents. Paralysis of facial nerve has a tremendous impact on patient as well as parents particularly when a pediatric patient is affected.  It is regarded as a diagnosis of exclusion.  Bell's palsy in infants is rare than adults and diagnosis is made on the basis of exclusion.Aim and Objectives:Clinical diagnosis and management of Bell's palsy among infants from a tertiary care hospital of eastern India.Material and Methods:In this prospective study, we have documented detail clinical manifestation and management of infants of Bell's palsy from the pediatric age group. When an infant presents with facial nerve paralysis, a full clinical history and detailed examination were recommended for accurate diagnosis.  Simultaneously, the parents were reassured and the prognosis was explained to the parents.  Oral steroids along with physiotherapy were started in the outdoor basis.Results:We diagnosed six infants of Bell's palsy in age group of 5 months to 12 months. Among them 4 females and rest 3 were male. These Infants showed improvement with complete recovery in 83% cases within 3 weeks whereas partial recovery was seen in rest.Conclusion:In this study, we find out that, oral steroids along with physiotherapy and eye care are effective for Bell's palsy in infants.Keywords:Bell's palsy, infant, facial nerve, oral steroid
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