Saponaria officinalis Seeds Germination Morphology and Biology

This work deals with the study of influence of terms and storage conditions on Saponaria officinalis seed quality, stored in different containers (paper, plastic, fabric and glass), in the different temperature conditions, under light or darkness. The morphology, biology of Saponaria officinalis seeds was described. Basing in the obtained results, we recommend to store Saponaria officinalis seeds within 3 months in paper container at the temperature of - 18˚С

Drug Plant Seed Viability Preservation by Cryoconservation

The article considers the possibility of cryopreservation of seeds of several species of drug plants in Central Kazakhstan – Tanacetum ulutavicum, Niedzwedzkia semiretschenskia, Rhaponticum carthamoides. To increase the amount of viable seeds after liquid nitrogen freezing, we used different defrosting temperatures, deposited seeds with different moisture contents and used different containers for cryopreservation. Recommendations, concerning conditions of cryopreservation of seeds of these drug plant species were developed, basing on the obtained results

Effect of unconventional physical treatments on the properties of anodic oxide coatings obtained in a suspension electrolyte

The new data for certain physical effects on anode-oxide coating deposition (ultrasonic field) and on coating (low-temperature plasma, thermal effects and short-time thermal shocks), formed in the electrolyte-suspension. The alumina powder is a dispersed phase in oxidizing AD-1M aluminum alloy. It is shown that the corrosion and thermal resistances are improved and the porosity is reduced under ultrasonic field conditions of oxidizing. The low-temperature plasma processing leads to crack formation on the coating surface independent of alumina presence

Study of Water-holding Indicators of Various Environmental Groups of Trees and Shrubs under Zhezkazgan Region Conditions

The article studies water content of leaves and water-holding capacity of trees and shrubs of twelve kinds of plants. Water-holding capacity analysis was conducted in summer, which is stressful for the plants. It was determined that water-holding capacity of plants is minimal in spring and summer, while these functions increase in mid and late summer. Basing on these data, all trees and shrubs were divided into 3 groups by water-holding capacity: low, medium and high. Plants of the third group are recommended for the semi-arid zone Zhezkazgan Region landscaping

Isolation and In Silico Anti-SARS-CoV-2 Papain-Like Protease Potentialities of Two Rare 2-Phenoxychromone Derivatives from Artemisia spp.

Two rare 2-phenoxychromone derivatives, 6-demethoxy-4`-O-capillarsine (1) and tenuflorin C (2), were isolated from the areal parts of Artemisia commutata and A. glauca, respectively, for the first time. Being rare in nature, the inhibition potentialities of 1 and 2 against SARS-CoV-2 was investigated using multistage in silico techniques. At first, molecular similarity and fingerprint studies were conducted for 1 and 2 against co-crystallized ligands of eight different COVID-19 enzymes. The carried-out studies indicated the similarity of 1 and 2 with TTT, the co-crystallized ligand of COVID-19 Papain-Like Protease (PLP), (PDB ID: 3E9S). Therefore, molecular docking studies of 1 and 2 against the PLP were carried out and revealed correct binding inside the active site exhibiting binding energies of −18.86 and −18.37 Kcal/mol, respectively. Further, in silico ADMET in addition to toxicity evaluation of 1 and 2 against seven models indicated the general safety and the likeness of 1 and 2 to be drugs. Lastly, to authenticate the binding and to investigate the thermodynamic characters, molecular dynamics (MD) simulation studies were conducted on 1 and PLP.Peer Reviewe

Jusanin, a New Flavonoid from Artemisia commutata with an In Silico Inhibitory Potential against the SARS-CoV-2 Main Protease

A new flavonoid, Jusanin, (1) has been isolated from the aerial parts of Artemisia commutata. The chemical structure of Jusanin has been elucidated using 1D, 2D NMR, and HR-Ms spectroscopic methods to be 5,2′,4′-trihydroxy-6,7,5′-trimethoxyflavone. Being new in nature, the inhibition potential of 1 has been estimated against SARS-CoV-2 using different in silico techniques. Firstly, molecular similarity and fingerprint studies have been conducted for Jusanin against co-crystallized ligands of eight different SARS-CoV-2 essential proteins. The studies indicated the similarity between 1 and X77, the co-crystallized ligand SARS-CoV-2 main protease (PDB ID: 6W63). To confirm the obtained results, a DFT study was carried out and indicated the similarity of (total energy, HOMO, LUMO, gap energy, and dipole moment) between 1 and X77. Accordingly, molecular docking studies of 1 against the target enzyme have been achieved and showed that 1 bonded correctly in the protein’s active site with a binding energy of −19.54 Kcal/mol. Additionally, in silico ADMET in addition to the toxicity evaluation of Jusanin against seven models have been preceded and indicated the general safety and the likeness of Jusanin to be a drug. Finally, molecular dynamics simulation studies were applied to investigate the dynamic behavior of the Mpro-Jusanin complex and confirmed the correct binding at 100 ns. In addition to 1, three other metabolites have been isolated and identified to be сapillartemisin A (2), methyl-3-[S-hydroxyprenyl]-cumarate (3), and β-sitosterol (4).Peer Reviewe

Effect of unconventional physical treatments on the properties of anodic oxide coatings obtained in a suspension electrolyte

The new data for certain physical effects on anode-oxide coating deposition (ultrasonic field) and on coating (low-temperature plasma, thermal effects and short-time thermal shocks), formed in the electrolyte-suspension. The alumina powder is a dispersed phase in oxidizing AD-1M aluminum alloy. It is shown that the corrosion and thermal resistances are improved and the porosity is reduced under ultrasonic field conditions of oxidizing. The low-temperature plasma processing leads to crack formation on the coating surface independent of alumina presence

Effect of unconventional physical treatments on the properties of anodic oxide coatings obtained in a suspension electrolyte

The new data for certain physical effects on anode-oxide coating deposition (ultrasonic field) and on coating (low-temperature plasma, thermal effects and short-time thermal shocks), formed in the electrolyte-suspension. The alumina powder is a dispersed phase in oxidizing AD-1M aluminum alloy. It is shown that the corrosion and thermal resistances are improved and the porosity is reduced under ultrasonic field conditions of oxidizing. The low-temperature plasma processing leads to crack formation on the coating surface independent of alumina presence

Effect of unconventional physical treatments on the properties of anodic oxide coatings obtained in a suspension electrolyte

The new data for certain physical effects on anode-oxide coating deposition (ultrasonic field) and on coating (low-temperature plasma, thermal effects and short-time thermal shocks), formed in the electrolyte-suspension. The alumina powder is a dispersed phase in oxidizing AD-1M aluminum alloy. It is shown that the corrosion and thermal resistances are improved and the porosity is reduced under ultrasonic field conditions of oxidizing. The low-temperature plasma processing leads to crack formation on the coating surface independent of alumina presence

Geographical innovations in the flora of the Mangystau region

This article gives the new 7 species to the flora of vascular plants of Mangystau region (Artemisia sieversiana Willd., Ribes aureum Pursh, Tulipa gerneriana L. (T. schrenkii Regn. M. Roem., Tulipa patens Agardh ex Schult. & Schult.fil, Malus siversii (Ledeb.) M. Roem., Urtica dioica L. and Lonicera tatarica L.). The plants are discovered during expeditionary research 2013-2018 on the territory of the Western Karatau Range, the South Aktau Range, the North Ustyurt Plateau and the Tyubka-ragan Peninsula. The short information on floristic innovations is given. The updated composition of the flora of vascular plants of the Mangystau region was 684 species