An annotated list and current state of ichthyofauna of the Middle Ob River basin

The paper contains a complete annotated list of freshwater ichthyofauna of the Middle Ob River basin. The list is based on an analysis of publications and on the results of the authors’ research, and it includes 43 species in two classes, 9 orders, 12 families, and 30 genera. Ten of all listed species are introduced and only seven are naturalized. For each species, taxonomic comments are provided where necessary and conservation status, distribution within the Middle Ob River basin, abundance and commercial value are indicated. Latin and English names are given

An annotated list and current state of ichthyofauna of the Middle Ob River basin

The paper contains a complete annotated list of freshwater ichthyofauna of the Middle Ob River basin. The list is based on an analysis of publications and on the results of the authors’ research, and it includes 43 species in two classes, 9 orders, 12 families, and 30 genera. Ten of all listed species are introduced and only seven are naturalized. For each species, taxonomic comments are provided where necessary and conservation status, distribution within the Middle Ob River basin, abundance and commercial value are indicated. Latin and English names are given

<i>cis</i>-Restricted 3‑Aminopyrazole Analogues of Combretastatins: Synthesis from Plant Polyalkoxybenzenes and Biological Evaluation in the Cytotoxicity and Phenotypic Sea Urchin Embryo Assays

We have synthesized a series of novel <i>cis</i>-restricted 4,5-polyalkoxydiaryl-3-aminopyrazole analogues of combretastatins via short synthetic sequences using building blocks isolated from dill and parsley seed extracts. The resulting compounds were tested in vivo in the phenotypic sea urchin embryo assay to reveal their antimitotic and antitubulin effects. The most potent aminopyrazole, <b>14a</b>, altered embryonic cell division at 10 nM concentration, exhibiting microtubule-destabilizing properties. Compounds <b>12a</b> and <b>14a</b> displayed pronounced cytotoxicity in the NCI60 anticancer drug screen, with the ability to inhibit growth of multi-drug-resistant cancer cells