Estrategias de Afrontamiento en educandos de 4to y 5to año de secundaria de un Colegio Público de Lima Metropolitana

La investigación tuvo como objetivo determinar el nivel de las estrategias de afrontamiento en educandos de 4to y 5to año de secundaria de un colegio público de Lima Metropolitana, Para ello se utilizó la prueba psicométrica Escalas de afrontamiento para adolescentes (ACS) de Frydenberg y Lewis (1997) revisada y adaptada en Lima, por Beatriz Canessa (2002).The research aimed to determine the level of coping strategies in students of 4th and 5th year of secondary of a public educational institution of Metropolitan Lima. This test was used psychometric scales of coping for adolescents (ACS) Frydenberg and Lewis (1997) adapted and revised in Lima, Peru va Beatriz Canessa (2002)

Estrategias de Afrontamiento en educandos de 4to y 5to año de secundaria de un Colegio Público de Lima Metropolitana

La investigación tuvo como objetivo determinar el nivel de las estrategias de afrontamiento en educandos de 4to y 5to año de secundaria de un colegio público de Lima Metropolitana, Para ello se utilizó la prueba psicométrica Escalas de afrontamiento para adolescentes (ACS) de Frydenberg y Lewis (1997) revisada y adaptada en Lima, por Beatriz Canessa (2002).The research aimed to determine the level of coping strategies in students of 4th and 5th year of secondary of a public educational institution of Metropolitan Lima. This test was used psychometric scales of coping for adolescents (ACS) Frydenberg and Lewis (1997) adapted and revised in Lima, Peru va Beatriz Canessa (2002)

Pharmacoepigenetics in Heart Failure

Epigenetics studies inheritable changes of genes and gene expression that do not concern DNA nucleotide variation. Such modifications include DNA methylation, several forms of histone modification, and microRNAs. From recent studies, we know not only that genetic changes account for heritable phenotypic variation, but that epigenetic changes also play an important role in the variation of predisposition to disease and to drug response. In this review, we discuss recent evidence of epigenetic changes that play an important role in the development of cardiac hypertrophy and heart failure and may dictate response to therapy

Genetic variability of arrhenotokous and thelytokous Venturiacanescens (Hymenoptera)

The ichneumonid wasp Venturia canescens (Hymenoptera) has been studied extensively for foraging behaviour and population dynamics of sexually (arrhenotokous) and parthenogenetically (thelytokous) reproducing individuals. Here we report the development of a set of microsatellite markers for V.canescens and use them to show that arrhenotokous individuals have more genetic variability than thelytokous ones, which are even homozygous for all tested loci. Crosses between arrhenotokous individuals suggested one marker, Vcan071, to be linked with the Complementary Sex Determiner (CSD) locus and one, Vcan109, with the Virus Like Protein (vlp-p40) locus. The genome size of V. canescens was estimated to be 274–279 Mb. We discuss how both reproductive modes can give rise to the observed genetic variability and how the new markers can be used for future genetic studies of V. canescens

Effects of the COVID-19 Pandemic on Physical Activity in Chronic Diseases: A Systematic Review and Meta-Analysis

This work was supported by the Spanish Ministry of Education by a FPU ("Formacion Profesorado Universitario") grant for the authors Andres Calvache-Mateo and Laura Lopez-Lopez (grant number, FPU:19/02609, FPU:17/00408).The management of chronic diseases (CD) includes physical activity (PA). It is necessary to determine the effects of COVID-19 restrictions in CD. The aim was to review the research related to PA levels before and during the COVID-19 pandemic in people with CD. This review was designed according to PRISMA guidelines and registered in PROSPERO: CRD42020218825. The search was performed in CINAHL, Medline, Scopus, and Web of Science up to January 2021. The PICOS recommendations were applied. The search was conducted by two reviewers, who completed the data extraction of included articles. Methodological quality was assessed using the STROBE checklist, and a meta-analysis was conducted. The literature search strategy identified 227 articles. Five studies remained and were included. Only three studies were included in the meta-analysis. Two articles used accelerometers to objectively compare PA levels before and during the pandemic. Three studies made this comparison using an online survey. All articles showed a decrease in PA levels during the COVID-19 pandemic. The meta-analysis showed a significant reduction in PA levels during pandemic. PA levels during the COVID-19 pandemic have been reduced with respect to previous levels of PA in patients with CD.German Research Foundation (DFG) FPU:19/02609 FPU:17/0040

Immunohistological study of the unexplored vomeronasal organ of an endangered mammal, the dama gazelle (Nanger dama)

Dama gazelle is a threatened and rarely studied species found primarily in northern Africa. Human pressure has depleted the dama gazelle population from tens of thousands to a few hundred individuals. Since 1970, a founder population consisting of the last 17 surviving individuals in Western Sahara has been maintained in captivity, reproducing naturally. In preparation for the future implementation of assisted reproductive technology, certain aspects of dama gazelle reproductive biology have been established. However, the role played by semiochemical-mediated communications in the sexual behavior of dama gazelle remains unknown due partially to a lack of a neuroanatomical or morphofunctional characterization of the dama gazelle vomeronasal organ (VNO), which is the sensory organ responsible for pheromone processing. The present study characterized the dama gazelle VNO, which appears fully equipped to perform neurosensory functions, contributing to current understanding of interspecies VNO variability among ruminants. By employing histological, lectin-histochemical, and immunohistochemical techniques, we conducted a detailed morphofunctional evaluation of the dama gazelle VNO along its entire longitudinal axis. Our findings of significant structural and neurochemical transformation along the entire VNO suggest that future studies of the VNO should take a similar approach. The present study contributes to current understanding of dama gazelle VNO, providing a basis for future studies of semiochemical-mediated communications and reproductive management in this speciesThis work was partially supported by a grant from “Consello Social Universidade de Santiago de Compostela” 2022-PU004S

Impact of Host Genetics and Biological Response Modifiers on Respiratory Tract Infections

Biological response modifiers; Immunogenetics; Inborn errorsModificadors de la resposta biològica; Immunogenètica; Errors congènitsModificadores de la respuesta biológica; Inmunogenética; Errores congénitosHost susceptibility to respiratory tract infections (RTI) is dependent on both genetic and acquired risk factors. Repeated bacterial and viral RTI, such as pneumonia from encapsulated microorganisms, respiratory tract infections related to respiratory syncytial virus or influenza, and even the development of bronchiectasis and asthma, are often reported as the first symptom of primary immunodeficiencies. In the same way, neutropenia is a well-known risk factor for invasive aspergillosis, as well as lymphopenia for Pneumocystis, and mycobacterial infections. However, in the last decades a better knowledge of immune signaling networks and the introduction of next generation sequencing have increased the number and diversity of known inborn errors of immunity. On the other hand, the use of monoclonal antibodies targeting cytokines, such as tumor necrosis factor alpha has revealed new risk groups for infections, such as tuberculosis. The use of biological response modifiers has spread to almost all medical specialties, including inflammatory diseases and neoplasia, and are being used to target different signaling networks that may mirror some of the known immune deficiencies. From a clinical perspective, the individual contribution of genetics, and/or targeted treatments, to immune dysregulation is difficult to assess. The aim of this article is to review the known and newly described mechanisms of impaired immune signaling that predispose to RTI, including new insights into host genetics and the impact of biological response modifiers, and to summarize clinical recommendations regarding vaccines and prophylactic treatments in order to prevent infections

Protocol d'actuació per al control i prevenció de l'hepatitis A

Hepatitis A; Malalties transmissibles; EpidemiologiaHepatitis A; Enfermedades transmisibles; EpidemiologíaHepatitis A; Transmissible diseases; EpidemiologyProtocol d'actuació dirigit als professionals de la salut per al control i la prevenció de l'hepatitis A.Protocolo de actuación dirigido a los profesionales de la salud para el control y la prevención de la hepatitis A.Action protocol adressed to health professionals about the control and prevention of hepatitis A

Protocol d’actuació per a la prevenció i el control del xarampió

Malalties transmissibles; Xarampió; PrevencióEnfermedades transmisibles; Sarampión; PrevenciónCommunicable Diseases; Measles; PreventionProtocol d'actuació dirigit als professionals de la salut per a la prevenció i el control del xarampió. Descriu les actuacions a seguir quan es declara un cas de xarampió; quins contactes i quins àmbits són candidats a les mesures de control.Protocolo de actuación dirigido a los profesionales de la salud para la prevención y el control del sarampión. Describe las actuaciones a seguir cuando se declara un caso de sarampión; qué contactos i qué ámbitos son candidatos a las medidas de control