Malleus maleficarum : in tres divisus partes : concurrentia ad maleficia, maleficiorum effectus, remedia adversus maleficia / Henrici Institoris Kramer, Iacobo Sprengero. Seconda e terza parte

Malleus maleficarum : in tres divisus partes : concurrentia ad maleficia, maleficiorum effectus, remedia adversus maleficia / Henrici Institoris Kramer, Iacobo Sprengero. - Rist. anast Aicurzio : Gruppo editoriale Castel Negrino, stampa 2013 737 [i.e. 755], [44] p. ; 24 cm Tit. della cop Ripr. facs. dell'ed.: Francofurti ad Moenum : apud Nicolaum Bessaum, 1580 4. rist

Malleus maleficarum : in tres divisus partes : concurrentia ad maleficia, maleficiorum effectus, remedia adversus maleficia / Henrici Institoris Kramer, Iacobo Sprengero. - Prima parte

Malleus maleficarum : in tres divisus partes : concurrentia ad maleficia, maleficiorum effectus, remedia adversus maleficia / Henrici Institoris Kramer, Iacobo Sprengero. - Rist. anast Aicurzio : Gruppo editoriale Castel Negrino, stampa 2013 737 [i.e. 755], [44] p. ; 24 cm Tit. della cop Ripr. facs. dell'ed.: Francofurti ad Moenum : apud Nicolaum Bessaum, 158

Memòria Digital de Catalunya

Precedeix el text (f. sign. [ ]1): Iohannes Philippus de Lignamine Siculus eques christiane religionis principibus cunctisq[ue] fidelibus S.P.DTít. i menció de responsabilitat obtinguts de l'epígraf del f. sign. [ ]2Peu d'impr. obtingut dels repertoris. GW el data post. a 1482, IERS i IGI ca. 1490. A la fi del text (f. sign. [ ]8): Datum in Slechstat die x mensis Augusti anno D[omi]ni millesimo quadringentesimo octuagesimo secu[n]doSignatures: [ ]8Tipus gòticsEspais en blanc per a les caplletre

Obesity-induced cognitive impairment in older adults: a microvascular perspective

Over two-thirds of individuals aged 65 and older are obese or overweight in the United States. Epidemiological data show an association between the degree of adiposity and cognitive dysfunction in the elderly. In this review, the pathophysiological roles of microvascular mechanisms, including impaired endothelial function and neurovascular coupling responses, microvascular rarefaction, and blood-brain barrier disruption in the genesis of cognitive impairment in geriatric obesity are considered. The potential contribution of adipose-derived factors and fundamental cellular and molecular mechanisms of senescence to exacerbated obesity-induced cerebromicrovascular impairment and cognitive decline in aging are discussed

The social cognition of medical knowledge, with special reference to childhood epilepsy

This paper arose out of an engagement in medical communication courses at a Gulf university. It deploys a theoretical framework derived from a (critical) sociocognitive approach to discourse analysis in order to investigate three aspects of medical discourse relating to childhood epilepsy: the cognitive processes that are entailed in relating different types of medical knowledge to their communicative context; the types of medical knowledge that are constituted in the three different text types analysed; and the relationship between these different types of medical knowledge and the discursive features of each text type. The paper argues that there is a cognitive dimension to the human experience of understanding and talking about one specialized from of medical knowledge. It recommends that texts be studied in medical communication courses not just in terms of their discrete formal features but also critically, in terms of the knowledge which they produce, transmit and reproduce

The modified 2VO ischemia protocol causes cognitive impairment similar to that induced by the standard method, but with a better survival rate

Permanent bilateral occlusion of the common carotid arteries (2VO) in the rat has been established as a valid experimental model to investigate the effects of chronic cerebral hypoperfusion on cognitive function and neurodegenerative processes. Our aim was to compare the cognitive and morphological outcomes following the standard 2VO procedure, in which there is concomitant artery ligation, with those of a modified protocol, with a 1-week interval between artery occlusions to avoid an abrupt reduction of cerebral blood flow, as assessed by animal performance in the water maze and damage extension to the hippocampus and striatum. Male Wistar rats (N = 47) aged 3 months were subjected to chronic hypoperfusion by permanent bilateral ligation of the common carotid arteries using either the standard or the modified protocol, with the right carotid being the first to be occluded. Three months after the surgical procedure, rat performance in the water maze was assessed to investigate long-term effects on spatial learning and memory and their brains were processed in order to estimate hippocampal volume and striatal area. Both groups of hypoperfused rats showed deficits in reference (F(8,172) = 7.0951, P < 0.00001) and working spatial memory [2nd (F(2,44) = 7.6884, P < 0.001), 3rd (F(2,44) = 21.481, P < 0.00001) and 4th trials (F(2,44) = 28.620, P < 0.0001)]; however, no evidence of tissue atrophy was found in the brain structures studied. Despite similar behavioral and morphological outcomes, the rats submitted to the modified protocol showed a significant increase in survival rate, during the 3 months of the experiment (P < 0.02)