Yield, forage quality, residue nitrogen and nitrogen fixation of different forage legumes

Fixed nitrogen accumulated by legumes is the main nitrogen source for organic farming systems. Knowledge about the amount of fixed nitrogen, its pathways into forage yield, crop residues, soil-N and yield formation of the following crop is needed for designing crop rotations. In a field experiment conducted in Northern Germany differently managed (cut, mulched) legumes (red clover, alfalfa, white clover) in pure stands and in mixture with a companion grass (Lolium perenne) have been grown to determine Yield, forage-quality, N2-fixation and residue nitrogen. Cropped grass/legume reached higher N2-fixation than mulched. While green manure grass/legume left up to 296 kg ha-1 of N in mulch, stubble and roots on the field, most cropped grass/legume mixtures left less than 120 kg N ha-1 in crop residues. Cropped swards showed higher N2-fixation than the mulched mixtures. Swards with red clover or alfalfa reached higher legume contents and harvestable biomass than swards with white clover. Conclusions The results show that biomass production, forage yields, residue nitrogen and N fixation of grass/legume mixtures can be influenced by various combinations of legume species and management. The factors listed have to be considered carefully when planning crop rotations

Interactions of Generated Weather Raster and Soil Profiles in Simulating Adaptive Crop Management and Consequent Yields for Five Major Crops throughout a Region in Southern Germany

Klimaanpassung und MitigationThe ability of bioeconomic simulation modelling to realistically predict agricultural adaptation is limited by the degree of detail in crucial model components. Model robustness must be tested before localized calibrations can be applied to regions of heterogenous environmental conditions. The agent-based model FARMACTOR was used to simulate the timing of field management actions (planting, harvest etc.) in response to environmental conditions, and consequent yields of winter wheat, barley and rapeseed, spring barley and silage maize as the predominant crops in a distinct region of Germany, by linking weather data and the crop growth simulation model EXPERT-N. The integrated models were calibrated to observed experimental data and official phenological observations and then run from 1990 to 2009, forced with climate data from ERA-interim Reanalyses data which was downscaled with the Weather and Research Forecast (WRF) model to a 12 X 12 km² grid. Variability in regional soils was replicated with 10 different soil profiles mapped at 1/25,000 scale. The nature of the forcing climate data dictates temporal aggregation for analysis, so that validity is examined by comparing mean simulated planting and harvest dates and yields to official records in the area. The mean predicted planting dates are very close to observations over the period, within a few days of observations, but show less variance. Harvest dates are accurately predicted as well, within one to two weeks, and the variances are closer to observations. Predicted winter wheat yields are well simulated in comparison to observed data, but maize yields are underestimated, while winter and spring barley and winter rapeseed yields are greater than observed district ("Landkreis") yields. The degree of variance in simulated yields is acceptable in wheat, winter barley and maize, but excessive in spring barley and winter rapeseed. Cross-sectional examination of yields shows that the different soil profiles are responsible for more yield variance than simulated weather cells in all crops. While the coupled models appear accurate in predicting crop management dates and physiological development, the inaccuracy in yields in all crops except winter wheat calls into question the reliability of the integrated models when applied, as is, outside of calibration conditions. That soil parameterization is responsible for more variance than generated weather is helpful in seeking to improve performance and encouraging in terms of the method of weather generation. Reliable extension of the coupled models to include all soils in an area together with artificial spatial climatic variability may require regionalized calibration to increase crop model stability

Foodmaster and three stories

Graduation date: 2004The purpose of this thesis was to create a sustained piece of fiction that both\ud represented my growth as a writer throughout my time at Oregon State University, and\ud wove together a mixture of imagination, language, and creativity. My hope was to write\ud a novella that incorporated and drew from themes including work, community, and\ud family relationships, and also was an exploration in the very structure and form of literary\ud fiction.\ud After completing the novella, I found that similar themes continued to appear\ud within my fiction during my ongoing growth as a writer. What I ended up with was a\ud novella and collection of related stories that reflected the influences of my advisor Tracy\ud Daugherty and his tutelage, the courses that I took at this university and my\ud undergraduate university, and my own personal history.\ud This thesis was written over a two-year period, during which drafts of this novella\ud and stories were written and rewritten. Each story and chapter was submitted to a writing\ud workshop, read and edited by my major and minor advisor, and carefully reworked and\ud redrafted after much scrutiny and attention.\ud During the course of writing this thesis, many things influenced me, the most\ud prominent being the world of fiction that existed all around me. I was influenced by\ud fiction that I was reading in my course work, such as Donald Barthelme and Philip Roth,\ud but writers that I had grown up with, like Edgar Allen Poe and Ray Bradbury also\ud influenced me. Beyond the world of published fiction, I found not only influence, but\ud also more importantly inspiration from the work and criticism of the writers and students\ud within the Creative Writing Program here at Oregon State University.\ud The end result of these two years of work, study, writing, and criticism was a\ud piece of fiction that I am proud of, and plan to publish. This collection of fiction\ud represents not only a sustained study on the craft of creative writing, but also serves an\ud exploration of my own voice and style, and an awakening of my identity as a fiction\ud writer

Pharmacokinetic Properties of Liraglutide as Adjunct to Insulin in Subjects with Type 1 Diabetes Mellitus.

BACKGROUND: The pharmacokinetic properties of liraglutide, a glucagon-like peptide-1 receptor agonist approved for the treatment of type 2 diabetes mellitus (T2D), have been established in healthy individuals and subjects with T2D. Liraglutide has been under investigation as adjunct treatment to insulin in type 1 diabetes mellitus (T1D). This single-center, double-blind, placebo-controlled, crossover, clinical pharmacology trial is the first to analyze the pharmacokinetic properties of liraglutide as add-on to insulin in T1D. METHODS: Subjects (18-64 years; body mass index 20.0-28.0 kg/m(2); glycated hemoglobin ≤9.5 %) were randomized 1:1:1 to 0.6, 1.2, or 1.8 mg liraglutide/placebo. Each group underwent two 4-week treatment periods (liraglutide then placebo or placebo then liraglutide) separated by a 2- to 3-week washout. Both trial drugs were administered subcutaneously, once daily, as adjunct to insulin. A stepwise hypoglycemic clamp was performed at the end of each treatment period (data reported previously). Pharmacokinetic endpoints were derived from liraglutide concentration-time curves after the final dose and exposure was compared with data from previous trials in healthy volunteers and subjects with T2D. RESULTS: The pharmacokinetic properties of liraglutide in T1D were comparable with those observed in healthy volunteers and subjects with T2D. Area under the steady-state concentration-time curve (AUC) and maximum plasma concentration data were consistent with dose proportionality of liraglutide. Comparison of dose-normalized liraglutide AUC suggested that exposure in T1D, when administered with insulin, is comparable with that observed in T2D. CONCLUSIONS: Liraglutide, administered as adjunct to insulin in subjects with T1D, shows comparable pharmacokinetics to those in subjects with T2D. ClinicalTrials.gov Identifier: NCT01536665

An analysis of the cost and benefit of search interactions

Interactive Information Retrieval (IR) systems often provide various features and functions, such as query suggestions and relevance feedback, that a user may or may not decide to use. The decision to take such an option has associated costs and may lead to some benefit. Thus, a savvy user would take decisions that maximises their net benefit. In this paper, we formally model the costs and benefits of various decisions that users, implicitly or explicitly, make when searching. We consider and analyse the following scenarios: (i) how long a user's query should be? (ii) should the user pose a specific or vague query? (iii) should the user take a suggestion or re-formulate? (iv) when should a user employ relevance feedback? and (v) when would the "find similar" functionality be worthwhile to the user? To this end, we build a series of cost-benefit models exploring a variety of parameters that affect the decisions at play. Through the analyses, we are able to draw a number of insights into different decisions, provide explanations for observed behaviours and generate numerous testable hypotheses. This work not only serves as a basis for future empirical work, but also as a template for developing other cost-benefit models involving human-computer interaction

Neuromyelitis optica and pregnancy during therapeutic B cell depletion: infant exposure to anti-AQP4 antibody and prevention of rebound relapses with low-dose rituximab postpartum

Neuromyelitis optica (NMO) predominantly affects women, some in childbearing age, and requires early therapeutic intervention to prevent disabling relapses. We report an anti-AQP4 antibody-seropositive patient who became pregnant seven months after low-dose (100 mg) rituximab application. Pregnancy showed no complications, and low-dose rituximab restarted two days after delivery resulted in neurological stability for 24 months. Remarkably, her otherwise healthy newborn presented with anti-AQP4 antibody and reduced B lymphocyte counts in umbilical cord blood, which normalized three months later. Confirming and extending previous reports, our case suggests that low-dose rituximab might be compatible with pregnancy and prevent rebound NMO disease activity postpartum

Modelling interaction with economic models of search

Understanding how people interact when searching is central to the study of Interactive Information Retrieval (IIR). Most of the prior work has either been conceptual, observational or empirical. While this has led to numerous insights and findings regarding the interaction between users and systems, the theory has lagged behind. In this paper, we extend the recently proposed search economic theory to make the model more realistic. We then derive eight interaction based hypotheses regarding search behaviour. To validate the model, we explore whether the search behaviour of thirty-six participants from a lab based study is consistent with the theory. Our analysis shows that observed search behaviours are in line with predicted search behaviours and that it is possible to provide credible explanations for such behaviours. This work describes a concise and compact representation of search behaviour providing a strong theoretical basis for future IIR research

Evaluating multi-year, multi-site data on the energy balance closure of eddy-covariance flux measurements at cropland sites in southwestern Germany

The energy balance of eddy-covariance (EC) measurements is typically not closed, resulting in one of the main challenges in evaluating and interpreting EC flux data. Energy balance closure (EBC) is crucial for validating and improving regional and global climate models. To investigate the nature of the gap in EBC for agroecosystems, we analyzed EC measurements from two climatically contrasting regions (Kraichgau – KR – and Swabian Jura – SJ) in southwestern Germany. Data were taken at six fully equipped EC sites from 2010 to 2017. The gap in EBC was quantified by ordinary linear regression, relating the energy balance ratio (EBR), calculated as the quotient of turbulent fluxes and available energy, to the residual energy term. In order to examine potential reasons for differences in EBC, we compared the EBC under varying environmental conditions and investigated a wide range of possible controls. Overall, the variation in EBC was found to be higher during winter than summer. Moreover, we determined that the site had a statistically significant effect on EBC but no significant effect on either crop or region (KR vs SJ). The time-variable footprints of all EC stations were estimated based on data measured in 2015, complimented by micro-topographic analyses along the prevailing wind direction. The smallest mean annual energy balance gap was 17&thinsp;% in KR and 13&thinsp;% in SJ. Highest EBRs were mostly found for winds from the prevailing wind direction. The spread of EBRs distinctly narrowed under unstable atmospheric conditions, strong buoyancy, and high friction velocities. Smaller footprint areas led to better EBC due to increasing homogeneity. Flow distortions caused by the back head of the anemometer negatively affected EBC during corresponding wind conditions.</p

Does physiotherapy reduce the incidence of postoperative complications in patients following pulmonary resection via thoracotomy? a protocol for a randomised controlled trial

Background: Postoperative pulmonary and shoulder complications are important causes of postoperative morbidity following thoracotomy. While physiotherapy aims to prevent or minimise these complications, currently there are no randomised controlled trials to support or refute effectiveness of physiotherapy in this setting. Methods/Design: This single blind randomised controlled trial aims to recruit 184 patients following lung resection via open thoracotomy. All subjects will receive a preoperative physiotherapy information booklet and following surgery will be randomly allocated to a Treatment Group receiving postoperative physiotherapy or a Control Group receiving standard care nursing and medical interventions but no physiotherapy. The Treatment Group will receive a standardised daily physiotherapy programme to prevent respiratory and musculoskeletal complications. On discharge Treatment Group subjects will receive an exercise programme and exercise diary to complete. The primary outcome measure is the incidence of postoperative pulmonary complications, which will be determined on a daily basis whilst the patient is in hospital by a blinded assessor. Secondary outcome measures are the length of postoperative hospital stay, severity of pain, shoulder function as measured by the self-reported shoulder pain and disability index, and quality of life measured by the Medical Outcomes Study Short Form 36 v2 New Zealand standard version. Pain, shoulder function and quality of life will be measured at baseline, on discharge from hospital, one month and three months postoperatively. Additionally a subgroup of subjects will have measurement of shoulder range of movement and muscle strength by a blinded assessor. Discussion: Results from this study will contribute to the increasing volume of evidence regarding the effectiveness of physiotherapy following major surgery and will guide physiotherapists in their interventions for patients following thoracotomy. Trial registration: The study protocol is registered with the Australian and New Zealand Clinical Trials registry (ANZCTRN12605000201673)