The Correlation Between Body Fat Percentage and Peak Expiratory Flow in Children Aged 10-12 Years At SD Negeri 8 Dauh Puri

Background: The accumulation of fat decreases lung function. Peak expiratory flow is an indicator for assessing pulmonary function and can be used to identify the narrowing or obstruction of the airway. This study aimed to examine the correlation between body fat percentage and peak expiratory flow in children aged 10-12 years.Methods: This study was an analytical study with a cross-sectional design carried out in March 2019 at SD Negeri 8 Dauh Puri, Denpasar. Sampling was done by simple random sampling, and 84 samples were recruited who met the inclusion and exclusion criteria. Body fat percentage was measured using Bioelectric Impedance Analysis, while peak expiratory flow was measured using Peak Flow Meters. Data analysis was done using the Pearson Correlation test..Result: The Pearson Correlation Test showed a negative weak correlation between the percentage of body fat and peak expiratory flow with p=0.009 and a correlation coefficient of -0.284. It can be interpreted that the higher the body fat percentage, the higher the value of peak expiratory flow.Conclusion : There is a significant correlation between body fat percentage and peak expiratory flow in children aged 10-12 years at SD Negeri 8 Dauh Puri

Potensi Formulasi Self Microemulsifying Drug Delivery System (SMEDDS) Ekstrak Biji Kedelai (Glycine soja) Terhadap Penurunan Kolesterol pada Penyakit Jantung Koroner

Background: Coronary heart diseases (CHD) is a disorder that caused by blockage of coronary arteries due to the process of atherosclerosis which disrupts the blood supply to the heart muscle. According to Sample Registration System (SRS) Indonesia in 2014, CHD is a second highest cause of death after stroke that is 12,9% of all cause of death in Indonesia. Therefore, this study aims to examining the effect of soybean extract encapsulated with Self Microemulsifying Drug Delivery System (SMEDDS) on LDL levels in coronary heart model rats. Based on various study, isoflavone aglycone genistein is the main flavonoid in soybean seed that has potential as an antioxidant. To increase bioavailability of aglycone isoflavones, a SMEDDS is needed. In this regard, the purpose of this reseach is to examine the potential of soybean seed (Glycine soja) extract to reduced cholesterol in CHD.Methods: The method used is a literature review with literature sources in the form of relevant articles from the search engines, namely Google Scholar, Pubmed, ScienceDirect, and Research Gate. Inclusion criteria included journals containing the keywords “soybean (Glycine soja)”, “Coronary Heart Disease”, “SMEDDS”, and “genistein isoflavone aglycone”.Result: Isoflavone aglycone as an potential antioxidant that is able to bind free radicals and and also lowering LDL, Triglycerides, and glucose levels in hyperglycemic states and increasing HDL.Conclusion : Soybean seed extract with SMEDDS encapsulation have a potential to decrease LDL level in coronary heart disease

Kualitas Tidur Buruk Memperlambat Waktu Reaksi Visual pada Mahasiswa Program Studi Sarjana Fisioterapi Fakultas Kedokteran Universitas Udayana

Background: College students are one of the groups that have a high risk of experiencing sleep deprivation and sleep disorders. In medical students, this is due to the high duration and intensity of education. Poor sleep quality causes impaired cognitive function, one of which is decreased reaction time. Students with faster reaction times have better cognitive status and academic performance. This study aims to determine how the relationship of sleep quality to reaction time with the type of simple reaction time (SRT) and choice reaction time (CRT) experiment in physiotherapy student at faculty of medicine, university of udayana.Methods: The cross-sectional study was conducted with simple random sampling technique. 45 students participated in this study. Sleep quality was measured with Pittsburgh Sleep Quality Index (PSQI) and reaction time using Deary-Liewald reaction time task with SRT and CRT types of experiment. Bivariate analysis was performed using the Spearman rho test.Result: 21 people (46.7%) had good sleep quality and 24 people (53.3%) had poor sleep quality. The results showed that there was a relationship between sleep quality and reaction time using CRT (p = 0.003) and there was no relationship between sleep quality and reaction time using SRT (p = 0.084).Conclusion: Poor sleep quality resulted in decreased reaction time with the CRT experiment type. The authors suggests research with different methods and populations, also add more control variables

Comparison of Antibacterial Activity of Sambiloto (Andrographis paniculata) Ethanol and Water Stem Extract Against Methicillin-Resistant Staphylococcus aureus (MRSA) ATCC 3351 In Vitro

Background: Methicillin-resistant Staphylococcus aureus (MRSA) is penicillin and cephalosporine resistant Staphylococcus aureus which is a major cause of nosocomial infection. Various studies have been conducted for resistant cases, especially herbs which have antibacterial activity. Sambiloto (Andrographis paniculata) is an example of herb which has antibacterial activity due to the presence of andrographolide. Andrographolide soluble in ethanol and poorly in water, while extraction with alcohol causes andrographolide’s degradation. This study aimed to investigate the antimicrobial activity of ethanol and water stem extract and compare them against MRSA ATCC 3351 in vitro.Methods: This is an experimental study with a post-test only control group design and conducted by disc diffusion technique to obtain an inhibition zone against MRSA.Result: The result of this study showed the mean inhibitory zone of ethanol stem extract was 5,87mm, 6,77mm, 7,87mm respectively for 25%, 50%, and 100% concentrations, while 1% concentration did not show antibacterial activity. Water stem extract at 1%, 25%, 50%, and 100% concentrations showed mean inhibitory zone was at 4,57mm, 7,17mm, 8,67mm, and 9,67mm respectively.Conclusion: Ethanol and water stem extract showed antibacterial activity against MRSA. The independent sample t-test didn’t show a difference between ethanol and water stem extract of Andrographis paniculata toward MRSA (p>0,05)

The Relationship Between Smartphone Addiction and Forward Head Posture in Junior High School Students in North Denpasar

ABSTRACTBackground:Nowadays, the smartphone has become an important requirement. The number of smartphone users and the duration of smartphone use is increasing rapidly, and the side effects can be detrimental one of them is forward head posture. The prevalence of forward head posture is greater women (24.1%) than men (9.1%).Methods:This study was an analytical observational study with a cross-sectional design.This research was conducted in April 2019 in SMP Negeri 2 Denpasar and SMP Negeri 4 Denpasar andincluding 56 samples, who were recruited through simple random sampling.Variables studied are smartphone addition was measured using the Smartphone Addiction Scale questionnaire, and forward head posture was measured by measuring craniovertebral angles. Data analysis was done using the Chi-Square test. Result: Based on this study, smartphone addiction was related to forward head posture. The research shows that as many as 45 samples had Smartphone Addiction (80.35%) while those who had forward head posture were 29 samples (51.78%).Conclusion : Ignorance of how to sort and choose the effects of globalization, especially smartphone use, which can lead to posture disorders. The factor recognized factors for the occurrences of the forward head posture the lack of education about ergonomic positions when using a smartphone. Parents are advised to set the right smartphone usage for children as early as possible

Prevalence of Genu Valgum in Children Aged 10-12 Years with Excessive Body Weight (Overweight/Obesity) in Sanur Kaja Village, Denpasar

Background: Overweight/obesity is a global health problem, both in developed and developing countries and the number of overweight/obese people increases every year. Being overweight during childhood increases the risk of obesity in adulthood and can lead to musculoskeletal disorders, one of which is genu valgum. The purpose of this study was to determine the prevalence of genu valgum in children aged 10-12 years who are overweight/obese in Sanur Kaja Village, Denpasar.Methods: This study was an observational study with a cross-sectional design conducted at elementary schools in Sanur Kaja Village in April 2019. The sampling technique used was purposive sampling. A total of 78 children were included in this study. The univariate analysis in this study was genu valgum, overweight/obesity, age, and gender.Result: The prevalence of genu valgum in children aged 10-12 years in Sanur Kaja Village was 46.7% in overweight children and 53.3% in obese children, with 30 people (38.5%) experiencing genu valgum out of the total sample of 78 people (100%).Conclusion: Based on the result of this study, the incidence of genu valgum was higher in children aged 10-12 years who were obese compared to children with overweight body mass index.  It is recommended that children who are obese and overweight to control their eating patterns, maintain normal body weight, and do enough physical activity

Antibacterial Activity from Temulawak Extract (Curcuma xanthorrhiza Roxb) on Growth Inhibition of Staphylococcus epidermidis In Vitro

Background: Infection is one of the main causes of disease in tropical regions like Indonesia. One of them can be caused by bacterial infection of Staphylococcus epidermidis. Staphylococcus epidermidis is an opportunistic bacterium that attacks individuals when the body's immune system is weak. The incidence of bacterial resistance to antibiotics that already exist so that requires an alternative treatment, one of which is the use of temulawak rhizome extract (Curcuma xanthorrhiza Roxb). Temulawak rhizome is one of the spices which is still often used as traditional medicine among Indonesian people. Temulawak rhizome extract is known to have a variety of chemical contents with active compounds in the form of essential oils xanthorrhizol and curcumin which can affect the rate of bacterial growth.Methods: This study aims to determine the antibacterial activity of temulawak rhizome extract on the growth of Staphylococcus epidermidis bacteria in vitro. The method used in this study is the true experimental post test only control group design. Samples were divided into four treatment concentrations such as the extract concentration of 25%, 50%, 75%, and 100% of temulawak rhizome which was tested by agar diffusion method (Kirby-Bauer).Result: The results of the analyze of variant (ANOVA) test showed a significant difference (p = 0,000). The temulawak extract could inhibit bacterial growth with a medium inhibitory response (5-10 mm). Temulawak rhizome extract showed the greatest inhibition at 100% concentration with an average inhibition zone diameter of 9.20 mm.Conclusion : The extract of temulawak rhizome has antibacterial activity. The higher concentration of temulawak rhizome extract (Curcuma xanthorrhiza Roxb), the greater ability to inhibit the growth of Staphylococcus epidermidis bacteria.

Immunonutrition and Hepatoprotectant Aspects of Moringa Oleifera Leaf Nanoemulsion Syrup as an Antituberculosis Adjuvant for Children with Tuberculosis

Tuberculosis in children is a global health problem that decreases the quality of life of children. Based on data from the Indonesian Ministry of Health in 2016, nearly 69.000 children had tuberculosis and the case keeps increasing every year. Moringa oleifera leaf nanoemulsion syrup has immunonutrition and hepatoprotectant effects in children with tuberculosis. Moringa oleifera leaf nanoemulsion syrup contains proteins, micronutrients, and minerals which have a biological role as an immunity agent and prevent toxic effects of tuberculosis drugs. Until now, the use of Moringa oleifera leaf nanoemulsion syrup has been carried out for the immunomodulatory and hepatoprotective aspects. Immunomodulatory and hepatoprotective aspects will be discussed further in this literature review. The sources of articles in this literature review are pubmed.com, ncbi.com, plosone.com, sciencedirect.com, and googleschoolar.com from 2010-2020, except when there is no new research against the article. The authors searched for the keywords: "immunonutrition", "tuberculosis in children", "hepatoprotectant", and "Moringa oleifera". As an immunomodulator, Moringa oleifera leaf nanoemulsion syrup stimulate activation of polimorphonuclear (PMN) cells. As a hepatoprotectant, Moringa oleifera leaf nanoemulsion syrup work by reducing the side effects of conventional tuberculosis drugs such as rifampicin by suppressing the action of cytochrome p450 (CYP1A2 and CYP2B), thus decreases the production of toxic hydrazine which causes liver toxicity in tuberculosis patient. Seeing the various interests in the immunomodulatory and hepatoprotective aspects, Moringa oleifera leaf nanoemulsion syrup can be used as an adjuvant therapy in overcoming tuberculosis in children by stimulating the activation of immunity cell such as PMN, increasing nutrient absorption, and suppressing the action of cytochrome p450 (CYP1A2 and CYP2B)