Diagrammatic Analysis of Charmless Three-Body B Decays

We express the amplitudes for charmless three-body B decays in terms of diagrams. In addition, we show how to use Dalitz-plot analyses to obtain decay amplitudes which are symmetric or antisymmetric under the exchange of two of the final-state particles. When annihilation-type diagrams are neglected, as in two-body decays, many of the exact, purely isospin-based results are modified, leading to new tests of the standard model (SM). Some of the tests can be performed now, and we find that present data agree with the predictions of the SM. Furthermore, contrary to what was thought previously, it is possible to cleanly extract weak-phase information from three-body decays, and we discuss methods for B -> K pi pi, K K Kbar, K Kbar pi and pi pi pi.Comment: 30 pages, 10 figures, reference updated, sentences added regarding indirect CP violation and CP of the final state. Significant text added describing how to obtain symmetric/antisymmetric decay amplitudes, results of the comparison of the predictions of the SM with present data for several decays, and the momentum dependence of the diagram

Hadronic B Decays: A General Approach

In this paper, we propose a general approach for describing hadronic B decays. Using this method, all amplitudes for such decays can be expressed in terms of contractions, though the matrix elements are not evaluated. Many years ago, Buras and Silvestrini proposed a similar approach. However, our technique goes beyond theirs in several ways. First, we include recent theoretical and experimental developments which indicate which contractions are negligible, and which are expected to be smaller than others. Second, we show that all B-decay diagrams can be simply expressed in terms of contractions. This constitutes a formal proof that the diagrammatic method is rigourous. Third, we show that one reproduces the relations between tree and electroweak-penguin diagrams described by Neubert and Rosner, and by Gronau, Pirjol and Yan. Fourth, although the previous results hold to all orders in alpha_s, we show that it is also possible to work order-by-order in this approach. In this way it is possible to make a connection with the matrix-element evaluation methods of QCD factorization (QCDfac) and perturbative QCD (pQCD). Finally, using the contractions approach, we re-evaluate the question of whether there is a ``B -> pi K puzzle.'' At O(alpha_s^0), we find that the diagram ratio |C'/T| is about 0.17, a factor of 10 too small to explain all the B -> pi K data. Both QCDfac and pQCD find that, at O(\alpha_s^1), the value of |C'/T'| may be raised to only about 2-3 times its lowest-order value. We therefore conclude that, assuming the effect is not a statistical fluctuation, it is likely that the value of |C'/T'| is similar to its O(\alpha_s^0) result, and that there really is a B -> pi K puzzle.Comment: 33 pages, plain latex, 10 figures (included

Nlrx1 regulates neuronal cell death

Background Regulation of cell death during neurodegeneration is one of the key factors that play a role in the speed at which a disease progresses. Out of several cellular pathways responsible for this progression, necrosis and apoptosis are situated on the opposite spectrum of cell death regulation. Necrosis produces an environment that promotes inflammation and cytotoxicity and apoptosis is a highly organized process that maintains tissue homeostasis. A recently discovered protein, Nlrx1, regulates inflammatory and cell death responses during infection. Findings Using transfections of N2A cell line, we demonstrate that Nlrx1 redirects cells away from necrosis and towards an apoptotic pathway following rotenone treatments. In addition, Nlrx1 promotes DRP1 phosphorylation and increases mitochondrial fission. Conclusion Our results suggest a novel molecular pathway for regulating mitochondrial dynamics and neuronal death. Nlrx1 may play an important role in neurodegenerative diseases, where necrosis is a prominent factor

Flavor SU(3) analysis of charmless B->PP decays

We perform a global fits to charmless $B \to PP$ decays which independently constrain the $(\bar\rho,\bar\eta)$ vertex of the unitarity triangle. The fitted amplitudes and phase are used to predict the branching ratios and CP asymmetries of all decay modes, including those of the $B_s$ system. Different schemes of SU(3) breaking in decay amplitude sizes are analyzed. The possibility of having a new physics contribution to $K \pi$ decays is also discussed.Comment: 3 pages, 2 figs. Talk given at EPS-HEP07 To appear in the proceedings, Reference adde

Obesity and Type 2 Diabetes Prevalence in Adults from Two Remote First Nations Communities in Northwestern Ontario, Canada

Objective. To assess the prevalence rates of obesity and type 2 diabetes in adults from two First Nations communities in northwestern Ontario, Canada. Methods. Body weight, height, and waist circumference as well as fasting and postprandial glucose levels following an oral glucose tolerance test were measured in 31 men and 41 women. Results. The mean age of the sample was 43 ± 13 y. The prevalence of obesity was 65.3% and was comparable between men and women. 90.3% of the individuals presented waist circumference levels greater than the thresholds associated with an increased risk of developing health problems. 26 of the 72 individuals (36.1%) were found to be type 2 diabetic. The prevalence of diabetes was not different between men and women. Conclusion. Using objective measurements, this study confirms that First Nations adults from remote communities of Canada continue to experience a disproportionately higher prevalence of obesity and type 2 diabetes than nonaboriginal Canadians

CP Violation and the CKM Matrix: Assessing the Impact of the Asymmetric B Factories

We update the profile of the CKM matrix. The apex (rhobar,etabar) of the Unitarity Triangle is given by means of a global fit. We propose to include therein sin2alpha from the CP-violating asymmetries in B0->rho+rho-, using isospin to discriminate the penguin contribution. The constraint from epsilon'/epsilon is briefly discussed. We study the impact from the measurement of the rare decay K+->pi+nunu-bar, and from a future observation of KL->pi0nunubar. The B system is investigated in detail, beginning with 2beta+gamma and gamma from B0->D(*)+-pi-+ and B+->D(*)0K+. A significant part of this paper is dedicated to B decays into pipi, Kpi, rhopi and rhorho. Various phenomenological and theoretical approaches are studied. Within QCD Factorization we find a remarkable agreement of the pipi and Kpi data with the other UT constraints. A fit of QCD FA to all pipi and Kpi data leads to precise predictions of the related observables. We analyze separately the B->Kpi decays, and in particular the impact of electroweak penguins in response to recent phenomenological discussions. We find no significant constraint on electroweak nor hadronic parameters. We do not observe any unambiguous sign of New Physics, whereas there is some evidence for potentially large rescattering effects. Finally we use a model-independent description of a large class of New Physics effects in both BBbar mixing and B decays, namely in the b->d and b->s gluonic penguin amplitudes, to perform a new numerical analysis. Significant non-standard corrections cannot be excluded yet, however standard solutions are favored in most cases.Comment: Final version accepted for publication in EPJ C, updated results and plots are available at: http://ckmfitter.in2p3.fr or http://www.slac.stanford.edu/xorg/ckmfitter/ (mirror

Flavor SU(3) analysis of charmless B meson decays to two pseudoscalar mesons

Global fits to charmless B --> PP decays in the framework of flavor SU(3) symmetry are updated and improved without reference to the \sin2\beta measured from the charmonium decay modes. Fit results directly constrain the (\bar\rho,\bar\eta) vertex of the unitarity triangle, and are used to predict the branching ratios and CP asymmetries of all decay modes, including those of the B_s system. Different schemes of SU(3) breaking in decay amplitude sizes are analyzed. The major breaking effect between strangeness-conserving and strangeness-changing decays can be accounted for by including a ratio of decay constants in tree and color-suppressed amplitudes. The possibility of having a new physics contribution to K \pi decays is also examined from the data fitting point of view.Comment: 22 pages and 2 figures; some comments and references added; more references added, version to appear in journa

Charmless B→PPB \to PP decays using flavor SU(3) symmetry

The decays of $B$ mesons to a pair of charmless pseudoscalar ($P$) mesons are analyzed within a framework of flavor SU(3). Symmetry breaking is taken into account in tree ($T$) amplitudes through ratios of decay constants; exact SU(3) is assumed elsewhere. Acceptable fits to $B \to \pi \pi$ and $B \to K \pi$ branching ratios and CP asymmetries are obtained with tree, color-suppressed ($C$), penguin ($P$), and electroweak penguin ($P_{EW}$) amplitudes. Crucial additional terms for describing processes involving $\eta$ and $\eta'$ include a large flavor-singlet penguin amplitude ($S$) as proposed earlier and a penguin amplitude $P_{tu}$ associated with intermediate $t$ and $u$ quarks. For the $B^+ \to \pi^+ \eta'$ mode a term $S_{tu}$ associated with intermediate $t$ and $u$ quarks also may be needed. Values of the weak phase $\gamma$ are obtained consistent with an earlier analysis of $B \to VP$ decays, where $V$ denotes a vector meson, and with other analyses of CKM parameters.Comment: 26 pages, 1 figure. To be submitted to Phys. Rev. D. Reference update

Appetite, gut hormone and energy intake responses to low volume sprint interval and traditional endurance exercise.

Sprint interval exercise improves several health markers but the appetite and energy balance response is unknown. This study compared the effects of sprint interval and endurance exercise on appetite, energy intake and gut hormone responses. Twelve healthy males [mean (SD): age 23 (3) years, body mass index 24.2 (2.9) kg m(-2), maximum oxygen uptake 46.3 (10.2) mL kg(-1) min(-1)] completed three 8 h trials [control (CON), endurance exercise (END), sprint interval exercise (SIE)] separated by 1 week. Trials commenced upon completion of a standardised breakfast. Sixty minutes of cycling at 68.1 (4.3) % of maximum oxygen uptake was performed from 1.75-2.75 h in END. Six 30-s Wingate tests were performed from 2.25-2.75 h in SIE. Appetite ratings, acylated ghrelin and peptide YY (PYY) concentrations were measured throughout each trial. Food intake was monitored from buffet meals at 3.5 and 7 h and an overnight food bag. Appetite (P 0.05). Therefore, relative energy intake (energy intake minus the net energy expenditure of exercise) was lower in END than that in CON (15.7 %; P = 0.006) and SIE (11.5 %; P = 0.082). An acute bout of endurance exercise resulted in lower appetite perceptions in the hours after exercise than sprint interval exercise and induced a greater 24 h energy deficit due to higher energy expenditure during exercise

Obesity and type 2 diabetes in Northern Canada’s remote First Nations communities: the dietary dilemma

First Nations populations in Northwestern Ontario have undergone profound dietary and lifestyle transformations in less than 50 years, which have contributed to the alarming rise in obesity and obesity-related diseases, in particular type 2 diabetes mellitus. Even though the genetic background of First Nations peoples differs from that of the Caucasians, genetics alone cannot explain such a high prevalence in obesity and type 2 diabetes. Modifications in lifestyle and diet are major contributors for the high prevalence of chronic diseases. What remains constant in the literature is the persistent view that locally harvested and prepared foods are of tremendous value to First Nations peoples providing important health and cultural benefits that are increasingly being undermined by westernbased food habits. However, the complexities of maintaining a traditional diet require a multifaceted approach, which acknowledges the relationship between benefits, risks and viability that cannot be achieved using purely conventional medical and biological approaches. This brief review explores the biological predispositions and potential environmental factors that contribute to the development of the high incidence of obesity and obesity-related diseases in First Nations communities in Northern Canada. It also highlights some of the complexities of establishing exact physiological causes and providing effective solutions