Stepen mikrobne kontaminacije i učestalost infekcija operativnog mesta u Centru za ortopediju i traumatologiju Kliničko-bolničkog centra u Kragujevcu

Introduction. The level of microbial contamination is an important risk factor for surgical site infections. The aim of this study was to investigate the frequency of surgical site infections in regard to the level of microbial contamination at the Department of Orthopedic and Traumatologic Surgery of the Clinical Hospital Center in Kragujevac. Material and methods. This study included 474 patients who underwent surgery in the period from January 1, 2002 to December 31, 2002 at the Department of Orthopedic and Traumatologic Surgery of the Clinical Hospital Center in Kragujevac. Hospital infections were identified using CDC definitions, modified to fit our circumstances. The traditional classification of surgical sites in regard to the level of microbial contamination includes three categories: clean, contaminated and dirty. Results The incidence of surgical site infections was higher at the Orthopedic Surgery Ward (5.94%) compared to Traumatologic Surgery Ward (5.02%). Additionally, a significantly higher frequency of deep surgical site infections, which were classified as clean were established at the Orthopedic Surgery Ward, in regard to the level of microbial contamination, whereas the greatest frequency of surface infections in clean surgical sites (p=0.000) were established at the Traumatologic Surgery Ward. Surgical site infections were more frequent in patients undergoing multiple surgeries at the Orthopedic Surgery Ward than in those treated at the Traumatologic Surgery Ward (p=0.037). Conclusion It is of utmost importance to estimate the frequency of surgical site infections and identify associated risk factors in order to undertake adequate measures for their prevention and control.Cilj rada bio je sagledavanje učestalosti infekcija operativnog mesta u odnosu na stepen mikrobne kontaminacije u Centru za ortopediju i traumatologiju Kliničko-bolničkog centra u Kragujevcu. Studijom incidencije infekcija operativnog mesta obuhvaćeno je 474 bolesnika koji su u periodu od 1.01.2002. do 31.12.2002. godine operisani u Centru za ortopediju i traumatologiju Kliničko-bolničkog centra u Kragujevcu. Na odeljenju Ortopedija zabeležena je značajno veća učestalost infekcija operativnog mesta (5,94%) u odnosu na kategoriju operativnog mesta prema stepenu mikrobne kontaminacije, nego na odeljenju Traumatologija (5,02%). Takođe, na odeljenju Ortopedija zabeležena je značajno veća učestalost dubokih infekcija operativnih mesta koja su prema stepenu mikrobne kontaminacije klasifikovana kao čista, dok je na odeljenju Traumatologija u čistih operativnih mesta nađena najveća učestalost površinskih infekcija operativnog mesta (p=0,000). Kod pacijenata koji su imali multiple (>1) operacije značajno češće su registrovane infekcije operativnog mesta na odeljenju Ortopedija nego na odeljenju Traumatologija, pri čemu su operativna mesta uglavnom klasifikovana kao čista (p=0,037)

Exploring opportunities and challenges of artificial intelligence and machine learning in higher education institutions

The way people travel, organise their time, and acquire information has changed due to information technologies. Artificial intelligence (AI) and machine learning (ML) are mechanisms that evolved from data management and developing processes. Incorporating these mechanisms into business is a trend many different industries, including education, have identified as game-changers. As a result, education platforms and applications are more closely aligned with learners’ needs and knowledge, making the educational process more efficient. Therefore, AI and ML have great potential in e-learning and higher education institutions (HEI). Thus, the article aims to determine its potential and use areas in higher education based on secondary research and document analysis (literature review), content analysis, and primary research (survey). As referent points for this research, multiple academic, scientific, and commercial sources were used to obtain a broader picture of the research subject. Furthermore, the survey was implemented among students in the Republic of Serbia, with 103 respondents to generate data and information on how much knowledge of AI and ML is held by the student population, mainly to understand both opportunities and challenges involved in AI and ML in HEI. The study addresses critical issues, like common knowledge and stance of research bases regarding AI and ML in HEI; best practices regarding usage of AI and ML in HEI; students’ knowledge of AI and ML; and students’ attitudes regarding AI and ML opportunities and challenges in HEI. In statistical considerations, aiming to evaluate if the indicators were considered reflexive and, in this case, belong to the same theoretical dimension, the Correlation Matrix was presented, followed by the Composite Reliability. Finally, the results were evaluated by regression analysis. The results indicated that AI and ML are essential technologies that enhance learning, primarily through students’ skills, collaborative learning in HEI, and an accessible research environment.info:eu-repo/semantics/publishedVersio

Deficijencija B12 vitamina kod deteta majke na veganskoj ishrani

Vitamin B12 deficiency usually occurs in exclusively breastfed infants whose mothers have pernicious anaemia or are vegetarian. Early treatment of vitamin B12 deficiency in infants can prevent potentially neurologic sequelae. A male child aged 13 months has been hospitalized due to failure to thrive, feeding problems, pallor, weakness and hypotonia. During the pregnancy mother did not eat meat and during lactation she also excluded eggs and milk. The child was exclusively breastfed. Laboratory investigations showed a haemoglobin level of 3.5 g/dL, haematocrit 10%, red blood cell count of 0.99 × 1012/L, white blood cell count of 4.23 × 109 /L and platelet count of 55 × 109 /L. Vitamin B12 level was low. A bone marrow aspiration finding was consistent with megaloblastic anaemia. The magnetic resonance imaging showed brain atrophy. Vitamin B12 in a dose of 10µg per kg was applied intramuscularly daily for 2 weeks, then once weekly. Three days after initiating B12 vitamin therapy there was an improvement in the blood count with the gradual improvement of neurological state. Vitamin B12 deficiency is a treatable cause of pancytopenia and neurological dysfunction in children and should be considered as differential diagnosis in an infant with neurological symptoms.Deficijencija B12 vitamina se obično javlja kod odojčadi koja su na prirodnoj ishrani a čije majke imaju pernicioznu anemiju ili su vegetarijanci. Pravovremeno lečenje deficijencije B12 vitamina kod odojčadi može da prevenira potencijalne neurološke posledice. Malo muško dete uzrasta 13 meseci je hospitalizovano zbog nenapredovanja, problema sa hranjenjem, bledila, slabosti i hipotonije.Tokom trudnoće majka nije jela meso dok je tokom dojenja iz ishrane isključila i jaja i mleko. Dete je isključivo dojeno. U laboratorijskim nalazima nivo hemoglobina je iznosio 3,5 g/dl, hematokrit 10%, broj eritrocita je bio 0.99×1012/L, broj leukocita 4.23×109 /L i broj trombocita 55×109 /L. Nivo B12 vitamina je bio snižen. Nalaz biopsije kostne srži ukazivao je na megaloblastnu anemiju. Na magnetnoj rezonanci endokranijuma viđena je atrofija mozga. Vitamin B12 u dozi od 10 mikrograma/kg primenjen je intramuskularno svakodnevno tokom 2 nedelje, potom jednom nedeljno.Tri dana od započinjanja terapije zabeleženo je poboljšanje hematoloških vrednosti uz postepeno poboljšanje neurološkog statusa. Deficijencija B12 vitamina je uzrok pancitopenije i neurološke disfuncije kod dece koju je moguće lečiti. Kod odojčeta sa neurološkim simptomima ova deficijencija treba da bude razmotrena kao diferencijalna dijagnoza

Laser Interaction with Material - Theory, Experiments and Discrepancies

The experimental treatment of chosen material with laser beams, starting from continuous wave up to fs pulses, produces the necessity to find the common and sophisticated theoretical approaches to interaction modeling. For chosen materials, some laser treatment and damage analyses are performed. The provoked stresses and parameters of transport processes (penetration depth) are calculated by using the programs for electrical circuit analyses. Some inconsistencies in the treatment of large area laser-material interaction are discussed

Actual contamination of the Danube and Sava Rivers at Belgrade (2013)

This study was focussed on a comprehensive investigation on the state of pollution of the Danube and Sava Rivers in the region of Belgrade. Different complementary analytical approaches were employed covering both i) organic contaminants in the river water by target analyses of hormones and neonicotinoids as well as non-target screening analyses and ii) heavy metals in the sediments. Finally, some common water quality parameters were analysed. The overall state of pollution is on a moderate level. Bulk parameters did not reveal any unusual observations. Moreover, quantification of preselected organic contaminants did not indicate to elevated pollution. More significant contaminations were registered for chromium, nickel, zinc and partially copper in sediments with values above the target values according to Serbian regulations. Lastly, non-target screening analysis revealed a wider spectrum of organic contaminants comprising pharmaceuticals, technical additives, personal care products and pesticides. The study presented a comprehensive view on the state of pollution of the Sava and Danube Rivers and is the base for setting up further monitoring programs. As a superior outcome, it was illustrated how different chemical analyses can result in different assessments of the river quality. A comparison of target and non-target analyses pointed to potential misinterpretation of the real state of pollution

Global, Regional, and National Levels and Trends in Burden of Oral Conditions from 1990 to 2017: A Systematic Analysis for the Global Burden of Disease 2017 Study

Government and nongovernmental organizations need national and global estimates on the descriptive epidemiology of common oral conditions for policy planning and evaluation. The aim of this component of the Global Burden of Disease study was to produce estimates on prevalence, incidence, and years lived with disability for oral conditions from 1990 to 2017 by sex, age, and countries. In addition, this study reports the global socioeconomic pattern in burden of oral conditions by the standard World Bank classification of economies as well as the Global Burden of Disease Socio-demographic Index. The findings show that oral conditions remain a substantial population health challenge. Globally, there were 3.5 billion cases (95% uncertainty interval [95% UI], 3.2 to 3.7 billion) of oral conditions, of which 2.3 billion (95% UI, 2.1 to 2.5 billion) had untreated caries in permanent teeth, 796 million (95% UI, 671 to 930 million) had severe periodontitis, 532 million (95% UI, 443 to 622 million) had untreated caries in deciduous teeth, 267 million (95% UI, 235 to 300 million) had total tooth loss, and 139 million (95% UI, 133 to 146 million) had other oral conditions in 2017. Several patterns emerged when the World Bank's classification of economies and the Socio-demographic Index were used as indicators of economic development. In general, more economically developed countries have the lowest burden of untreated dental caries and severe periodontitis and the highest burden of total tooth loss. The findings offer an opportunity for policy makers to identify successful oral health strategies and strengthen them; introduce and monitor different approaches where oral diseases are increasing; plan integration of oral health in the agenda for prevention of noncommunicable diseases; and estimate the cost of providing universal coverage for dental care

The relationship between the burnout syndrome and academic success of medical students: a cross-sectional study

The burnout syndrome may affect academic achievement, but research on burnout and academic success of medical students is sparse. This research aimed to estimate the prevalence of high risk of burnout in students of medicine and to investigate its association with academic performance. It included 760 full-time medical students who completed the survey (response rate = 90.9 %). A significant independent predictor for high burnout risk in students with lower grade point average (GPA) was male gender (adjusted OR=2.44; 95 % CI=1.14–5.23; P=0.022). Among students with higher GPA, high burnout risk was associated with the use of sedatives (adjusted OR=6.44; 95 % CI=1.80–22.99; P=0.004)

The level of knowledge of students of medical faculty kragujevac about nosocomial infections

OBJECTIVE: To investigate differences in clinical and pre-clinical medical students' knowledge of nosocomial infections (NI). DESIGN: Cross-sectional survey. RESULTS: Questionnaires were answered and returned by 352 of 453 student (77.7 %). The results indicated that students knew the definition of NI (70.1 % correct answers) and their reservoirs (86 %). The bacteria as etiological agents was the most frequent answer (76.4 %), but 30.9 % students did not knew at least one multidrug-resistant bacteria. About one half of the students (54.4 %) knew that contact was the most frequent mode of NI transmission, but hand washing as preventive measure was cited by only 18.8 % of students. Significantly statistical differences about NI in our country, etiology NI and preventive measures, and perception of risk for transmission of hepatitis B for health-care personnel were founded by year of training, by expectation that final-year medical students as more successfully, while pre-clinical students knew more about mode of NI transmission. Pre-clinical students who had previously finished nursing school knew more about multidrug-resistant bacteria than those who had finished some other secondary school, but showed a lower knowledge about definition and most important preventive measures of NI. Clinical students who had previously finished nursing school knew more about frequency NI in our country, reservoirs and preventive measures of NI than those who had finished some other secondary school. CONCLUSION: Data support the need for additional information about nosocomial infections, especially practical work in prevention, in order to get complete knowledge about nosocomial infections