10 research outputs found
Effect of Maternal Alcohol Consumption on Epididymal Growth in Neonatal Mice
A study was conducted to determine the effect of maternal alcohol consumption on the growth of epididymis in neonatal mice. Three groups of adult female mice were used. The pups of group 1 served as control while the pups of groups 2 and 3 were given 30% ethanol (v/v) during pregnancy and during pregnancy and lactation respectively. At 3, 4, 5 and 6 weeks of age, 10 male pups were randomly selected from each of the three groups and sacrificed. After sacrifice, the epididymis were dissected out and theirweights determined. The results of the study showed significant decrease in the weights and growth rates of the epididymis of the pups exposed to alcohol when compared with the controls. The study has therefore demonstrated that maternal alcohol intake during pregnancy and duringpregnancy and lactation affects the growth of epididymis of the neonates and that the epididymis of the neonates exposed to alcohol attempted catch-up growth with the control
Laser de baixa intensidade favorece a regeneração muscular em modelo experimental desnutrido e recuperado
Canine hip dysplasia: phenotypic scoring and the role of estimated breeding value analysis
Influence of Fetal Alcohol Exposure on the GABAergic Regulation of Growth Hormone Release in Postnatal Rats
The expression of CXCL13 and its relation to unfavorable clinical characteristics in young breast cancer
Peste des Petits Ruminants
Heartwater (or cowdriosis) is a tick-borne disease caused by Ehrlichia ruminantium, an obligatory intracellular bacterium of the order Rickettsiales, transmitted by several ticks of the genus Amblyomma. The organism is genetically highly variable which prevented until now the development of efficient vaccines. The disease is enzootic in sub-Sahelian Africa and in some Caribbean islands. It affects domestic and wild ruminants, the susceptibility to cowdriosis varying greatly between breeds and species: African wildlife shows mainly asymptomatic infections; local cattle breeds are generally protected due to enzootic stability; and introduced cattle breeds and small ruminants, even in enzootic regions, are usually susceptible to heartwater and can suffer high mortality rates. Cowdriosis is characterized by a sudden and acute fever followed by nervous, respiratory, and gastrointestinal symptoms and by hydrothorax and hydropericardium during postmortem examination. In West Africa, the only vector is Amblyomma variegatum, present in areas where pluviometry is higher than 500 mm. Therefore, animals of a high proportion of the Sahelian region are usually not infested by the tick and not infected by the bacterium. They are thus susceptible when introduced in southern parts of the Sahel or in the subhumid neighboring areas of the West African countries, for example during transhumance. Tetracyclines are effective drugs to treat heartwater when administered before occurrence of the nervous symptoms. Various vaccines have been tested, and are still developed, but, up to now, none of them showed enough effectiveness against all the field strains of E. ruminantium to allow its marketing. Prevention is therefore mainly achieved by drastic vector control or, on the contrary, acquisition of enzootic stability following tick infestation combined with tetracycline treatment as soon as hyperthermia occurs