The Impact of Yoga Practice on the Development of Flexibility among the Female Student’s Pedagogical Specialties in the Process of Physical Training of Higher Educational Institutions

Annotation. The purpose is to define an efficient impact of the specifically formed activities through Yoga practice on the development of flexibility among the female student’s in the process of physical training of higher educational institutions. Material. 96 female students have been participated in the pedagogical experiment. The research has been conducted during the one academic semester. The impact of Yoga practice on the indicator of flexibility was assessed at the end of the pedagogical experiment. The state of its development before and after the experiment was determined and compared. Results of the research. The results of the pedagogical experiment confirmed the successful influence of the offered activities through Yoga practice on the development of flexibility. It has been established that the systematic Yoga practicing contributes to the best manifestation of this physical quality. It has been proved that the use of Yoga practice has improved the flexibility indicators of the experimental group more in comparison with the control group. Conclusions. Practicing Yoga has positively impacted on the development of flexibility among female students. Whereas this quality is one of the indicators for assessing the physical condition of the graduates (18-20 years), it is expedient to include Yoga practicing in the curriculum of physical education for students of higher educational institutions and introduce this method of flexibility development in the process of physical education

Impact of Zweymüller Stem Modification on Clinical and Radiological Outcomes

Background. According to the analysis of large arthroplasty registers we have noted the increase in the use of non-cemented implants, because the latter shows the same results of implant survival as well as cemented implants. On the other hand, they can affect the quality of the bone around the implant in different ways. These components differ in shape, length, and surface properties. According to the analysis of the arthroplasty register of the Vreden National Medical Research Center of Traumatology and Orthopedics, a significant decrease of the Alloclassic femoral stem using can be noted. In parallel the use of its SL-PLUS MIA modification has increased significantly. Aims of the study: 1) to determine the influence of changes in the design of the Zweymüller-type femoral stem on midterm and long-term outcomes and its survival; 2) to identify the characteristics of adaptive remodeling of periprosthetic bone tissue around these femoral stems; 3) to determine risk factors for aseptic loosening of these femoral stems. Methods. 492 cases of hip arthroplasty using the Alloclassic and SL-PLUS MIA femoral stems were observed, with an average follow-up 78.6 months. The patients were divided into 2 groups according to the type of femoral stem. The assessment the hip articulation condition was carried out using the HHS and OHS. The intensity of the pain syndrome was assessed by VAS, and the level of patient’s satisfaction. The dynamic analysis of X-rays was also performed visually. Results. A significant improvement in clinical and functional results was observed according to the HHS and OHS in both groups of patients, regardless of the type of femoral stem. Analysis of X-rays over time showed differences in the behavior of these two femoral component models. The radiolucent lines around the femoral stem are absent in SL-PLUS MIA group, in Alloclassic stem group radiolucent lines are present even at a minimal period (12 months). We also found that a tight fit of Zweymüller femoral stems in the distal shaft is a risk factor for severe stress-shielding syndrome, especially in the funnel channels. But ceteris paribus, a distal tight fit of SL-PLUS MIA stems despite similar geometry of the distal part does not lead to such frequent manifestation of severe stress shielding. Conclusion. The change in Zweymüller stem design from Alloclassic to SL-PLUS MIA improved the nature of adaptive remodeling in the periprosthetic area of the femur. It may improve the long-term results of primary hip arthroplasty, but these differences require closer observation

Follow-Up After Hip and Knee Arthroplasty: a Review of the Literature and a Report on a Pilot Project at the Vreden National Medical Research Center of Traumatology and Orthopedics

Background. Today in our country, the follow-up of patients after arthroplasty is carried out in accordance with clinical guidelines, the wording of which is based on monographs from 2006, 2008, and 2014, in addition, clinical guidelines for follow-up do not take into account the results of treatment assessed by the patient himself. The purpose of this study was to examine existing systems and develop a proprietary follow-up system for patients after hip and knee arthroplasty. Results. A review of the literature revealed that follow-up of patients after arthroplasty is an unsolved problem, within which there is low coverage, reluctance or forgetfulness of the asymptomatic patient, the problem of accessibility of medical examinations, and an excessive financial burden on the health care system. Since 2022, fixed recommendations for follow-up after arthroplasty have been used in the clinical practice of our center in discharge epicrisis. Recommendations for the frequency of follow-up were formulated by experts based on a comprehensive review of the literature and their own experience. In the first three months, 221 hip and 235 knee evaluation questionnaires were collected through the proposed mechanism, with a progressive increase in the number of questionnaires based on weekly monitoring data. Conclusion. Unfortunately, the outpatient clinic system is not always able to provide qualitative monitoring of patients after arthroplasty due to various reasons, therefore, in our opinion, the implementation of the mechanism of remote monitoring of patients will allow detecting various complications at the stage of early diagnosis, which will contribute to prompt solution of these problems. The remote monitoring system is also an important source of scientific data

Inhibition of Protein Fibrillation by Hydrogen Sulfide<xref rid="fn1" ref-type="fn">¹</xref>

Amyloid fibrils are misfolded proteins, which are often associated with various neurodegenerative diseases such as Alzheimer’s. The amount of hydrogen sulfide (H2S) is known to be reduced in the brain tissue of people diagnosed with Alzheimer’s disease relative to that of healthy individuals. Hen Egg-White Lysozyme (HEWL) forms typical β-sheet-rich fibrils during 70 minutes at low pH and high temperatures. These results are consistent with the ThT findings that β-sheets structure is also present in myoglobin (Mb), and hemoglobin (Hb) in the presence of 45% TFE. The addition of H2S in the process completely inhibits the formation of amyloid fibrils in HEWL, Mb, and Hb as revealed by several spectroscopic techniques. Non-resonance Raman bands corresponding to disulfide (RSSR) vibrational modes in the 550-500 cm-1 spectral range decreases in intensity and is accompanied by the appearance of a new 490 cm-1 band assigned to the trisulfide group (RSSSR). Intrinsic tryptophan fluorescence shows a partial denaturation of HEWL containing trisulfide bonds. Overall, the Mb and Hb result ties excellent with the HEWL data showing that the presence of H2S during these proteins fibrillation processes protects the α-helical protein structures, preventing the formation of amyloids in these different proteins moieties

Designing a methodological concept for the diagnosis of early development of the main wheat diseases pathogens

The studies presented in the article were carried out in 2018-2019 on the experimental field of the All-Russian Research Institute of Biological Plant Protection. The aim of the research was to assess the feasibility of diagnosing the early development of major diseases pathogens based on the results of ground-based spectrometry and the use of phytomonitoring technology, taking into account the genotypes of different winter wheat varieties. There were three options of the experimental plots for the research: the 1st – protected against diseases by fungicides, the 2nd – with an artificial infectious background, the 3rd – with the natural development of diseases. According to the results of data analysis, the most significant changes in the spectral characteristics of the studied plant backgrounds were noted at the time of the first signs of disease in the form of a decrease in the spectral brightness coefficient in the near infrared range. Using special tools in the experimental plots, the following pathogens were identified before the appearing of disease symptoms: Blumeria graminis (DC.) Speer f. sp. tritici Marchal , Puccinia striiformis West., Pyrenophora tritici-repentis Died., Puccinia triticina Erikss. Data on the diseases development, plant infestation by pathogens are compared with spectrometric measurements

Development of Methods for Remote Monitoring of Leaf Diseases in Wheat Agrocenoses

The development of remote methods for diagnosing the state of crops using spectral equipment for remote sensing of the Earth and original monitoring tools is the most promising solution to the problem of monitoring diseases of wheat agrocenoses. A research site was created on the experimental field of the Federal Research Center of Biological Plant Protection. Within the experimental field with a total area of 1 ha, test plots were allocated to create an artificial infectious background, and the corresponding control plots were treated with fungicides. The research methodology is based on the time synchronization of high-precision ground-based spectrometric measurements with satellite and unmanned remote surveys and the comparison of the obtained data with phytopathological field surveys. Our results show that the least-affected plants predominantly had lower reflectance values in the green, red, and red-edge spectral ranges and high values in the near-infrared range throughout the growing season. The most informative spectral ranges when using satellite images and multispectral cameras placed on UAVs are the red and IR ranges. At the same time, the high frequency of measurements is of key importance for determining the level of pathogenic background. We conclude that information acquisition density does not play as significant of a role as the repetition of measurements when carrying out ground-based spectrometry. The use of vegetation indices in assessing the dynamics of the spectral images of various survey systems allows us to bring them to similar values

Structural Organization of Insulin Fibrils Based on Polarized Raman Spectroscopy: Evaluation of Existing Models

Many different proteins undergo misfolding and self-assemble into amyloid fibrils, resulting in a range of neurodegenerative diseases. The limitations of conventional methods of structural biology for fibril characterization have led to the use of polarized Raman spectroscopy for obtaining quantitative structural information regarding the organization of amyloid fibrils. Herein, we report the orientation of selected chemical groups and secondary structure elements in aligned insulin fibrils, including β-sheets, which possess a high level of orientation in the cross-β core, and α-helices in the disordered portions of the fibrils. Strong orientation of disulfide bonds in amyloid fibrils was also revealed, indicating their association with the fibril core. The determined orientation of chemical groups provides strong constraints for modeling the overall structure of amyloid fibrils, including the core and disordered parts. The developed methodology allows for the validation of structural models proposed in the literature for amyloid fibrils. Specifically, the polarized Raman data obtained herein strongly agreed with two insulin fibril models (Jiménez et al., <i>Proc. Natl. Acad. Sci. U. S. A.</i> <b>2002</b>, <i>99</i>, 9196–9201 and Ivanova et al., <i>Proc. Natl. Acad. Sci. U. S. A.</i> <b>2009</b>, <i>106</i>, 18990–18995) yet revealed significant qualitative and quantitative differences. This work demonstrates the great potential of polarized Raman spectroscopy for structural characterization of anisotropic biological species

Імперативи ефективного використання земельного та ресурсного потенціалу сільськогосподарських підприємств України

EN: The article considers the institutionalization of land relations and the imperatives of efficient use of land and resource potential of agricultural enterprises of Ukraine. Within the institutionalization of land relations, the methodical approach to complex estimation of effective use of land and resource potential of agricultural enterprises is substantiated, by definition of an integral indicator of efficiency (quantitative and qualitative characteristics of involved resources, productivity and efficiency) of basic kinds of activity of economic entities on agricultural lands. Indicators of transparency in the assessment of land and resource potential and indicators of land policy according to the level of their use in agriculture are proposed. Comprehensive criteria for assessing the components of the efficiency of the use of land and resource potential of agricultural enterprises are presented. The amount of rent for land shares and the amount of fertilizer application per 1 ha of sown area of agricultural enterprises of Ukraine are analyzed. The productive capacity of natural and potential yields for grain and legumes (excluding corn for grain) in Ukraine has been determined. The normative monetary value of 1 ha of arable land in rural areas is calculated on average for one region of Ukraine, adjusted for the natural yield of cereals and legumes, without taking into account the application of fertilizers. The forecast level of technical, social and economic efficiency of the use of land and resource potential of agricultural enterprises is presented./////////////UK:У статті розглянуто інституціоналізацію земельних відносин та імперативи ефективного використання земельного та ресурсного потенціалу сільськогосподарських підприємств України. У межах інституціоналізації земельних відносин обґрунтовано методичний підхід до комплексної оцінки ефективного використання земельного та ресурсного потенціалу сільськогосподарських підприємств шляхом визначення інтегрального показника ефективності (кількісних та якісних характеристик залучених ресурсів, продуктивності та ефективності) основних видів діяльності суб’єктів господарювання на землях сільськогосподарського призначення. Запропоновано показники прозорості оцінки земельного та ресурсного потенціалу та показники земельної політики відповідно до рівня їх використання у сільському господарстві. Представлені комплексні критерії оцінки складових ефективності використання земельних ресурсів та ресурсного потенціалу сільськогосподарських підприємств. Проаналізовано розмір орендної плати за земельні паї та обсяг внесення добрив на 1 га посівної площі сільськогосподарських підприємств України. Визначено виробничі можливості природних і потенційних врожаїв зернових і зернобобових культур (крім кукурудзи на зерно) в Україні. Нормативна грошова вартість 1 га ріллі в сільській місцевості розраховується в середньому за одним регіоном України з поправкою на природну врожайність зернових та зернобобових культур без урахування внесення добрив. Представлено прогнозний рівень технічної, соціальної та економічної ефективності використання земельного й ресурсного потенціалу сільськогосподарських підприємств