ARGİNAZ VE KLİNİK ÖNEMİ

Beş tip izoenzimi olan anginaz enzimi, karaciğerde kortizol ve glukagon ile düzenlenmekte, böbrekte ise testesterondan etkilenmektedir

Melatonin

Melatonin yaklaşık 50 yıl önce keşfedilmiş olup ve son yıllarda önemi daha çok anlaşılmış pineal bezden salınan bir hormondur. Vücut sıvılarındaki düzeyi gece maksimum düzeyde artarken, gündüz düşer. Yüksek diffüzyon yeteneği ve lipofilik yapısından dolayı mükemmel bir antioksidan olup, bilinen diğer antioksidanlardan daha güçlüdür. Antioksidan etkisi gerek in vitro, gerekse in vivo olarak yapılan çalışmalarla kanıtlanmıştır. Ayrıca son yıllarda melatoninin reprodüksiyonun düzenlenmesindeki rolü, immün sistem ile ilişkisi, beyin fonksiyonlarının kontrolündeki rolünü araştıran değişik alanlarda çalışmalar da yapılmıştır. Bu derlemede değişik alanlardaki melatonin ile ilgili yeni bilgiler sunulmuştur.TrMelatonin is a hormone which is realesed from pineal gland. Despite of it was found before 50 years, the importance melatonin has been discovered in the recent years. In the body fluids levels are maximized during the night whereas during the day melatonin are mininized. Due to high diffusion ability and highly lipophilic nature, melatonin is a perfect antioxidant and more powerful than the other known antioxidants. This effect of melatonin has been determined with in vitro and in vivo studies. In addition in recent years an increasing amount of data has been published involving a role of melatonin in order of reproduction, stimulate the immun system and in the control of brain function. In this review has been submitted the present knowledge on melatonin in several areas

Melatonin

Melatonin yaklaşık 50 yıl önce keşfedilmiş olup ve son yıllarda önemi daha çok anlaşılmış pineal bezden salınan bir hormondur. Vücut sıvılarındaki düzeyi gece maksimum düzeyde artarken, gündüz düşer. Yüksek diffüzyon yeteneği ve lipofilik yapısından dolayı mükemmel bir antioksidan olup, bilinen diğer antioksidanlardan daha güçlüdür. Antioksidan etkisi gerek in vitro, gerekse in vivo olarak yapılan çalışmalarla kanıtlanmıştır. Ayrıca son yıllarda melatoninin reprodüksiyonun düzenlenmesindeki rolü, immün sistem ile ilişkisi, beyin fonksiyonlarının kontrolündeki rolünü araştıran değişik alanlarda çalışmalar da yapılmıştır. Bu derlemede değişik alanlardaki melatonin ile ilgili yeni bilgiler sunulmuştur.TrMelatonin is a hormone which is realesed from pineal gland. Despite of it was found before 50 years, the importance melatonin has been discovered in the recent years. In the body fluids levels are maximized during the night whereas during the day melatonin are mininized. Due to high diffusion ability and highly lipophilic nature, melatonin is a perfect antioxidant and more powerful than the other known antioxidants. This effect of melatonin has been determined with in vitro and in vivo studies. In addition in recent years an increasing amount of data has been published involving a role of melatonin in order of reproduction, stimulate the immun system and in the control of brain function. In this review has been submitted the present knowledge on melatonin in several areas

Vitamin A and β-Carotene Levels During Pregnancy in Gaziantep, Turkey

Vitamin A levels during pregnancy have important influences on the health of pregnant women and the growing fetus. Therefore, plasma vitamin A and β-carotene concentrations during pregnancy in Turkish women living in Gaziantep city were investigated in a prevalence study. Optimum sample size was determined as 252 for vitamin A deficiency and vitamin A and β-carotene levels were examined in 427 pregnant women aged 14–44 years. Vitamin A and β-carotene concentrations were measured spectrophotometrically by Neeld Pearson method. Vitamin A and β-carotene concentrations in pregnant women were found as 1.14 ± 0.44 μmol/L, and 1.80 ± 0.66 μmol/L, respectively. Plasma vitamin A concentrations were found in low levels (<1.05 μmol/L) in 45.5 % of pregnant women. Vitamin A deficiency (<0.7 μmol/L) was determined in 16.9% of pregnant women. A mild negative correlation was obtained between the vitamin A concentration and pregnancy period. Vitamin A levels of pregnant women were decreased significantly in the third trimester (p<0.05). The findings of present study suggest that vitamin A levels of pregnant women were poor in the region. Therefore, the intake of vitamin A with foods should be improved. Supplementation of vitamin A might benefit at improving maternal and child health especially in high-risk groups especially in developing countries. Monitoring vitamin A levels in pregnant women is very important for also determining low and high levels