4,392 research outputs found

    Dark Energy Evolution and the Curvature of the Universe from Recent Observations

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    We discuss the constraints on the time-varying equation of state for dark energy and the curvature of the universe using observations of type Ia supernovae from Riess et al. and the most recent Supernova Legacy Survey (SNLS), the baryon acoustic oscillation peak detected in the SDSS luminous red galaxy survey and cosmic microwave background. Due to the degeneracy among the parameters which describe the time dependence of the equation of state and the curvature of the universe, the constraints on them can be weakened when we try to constrain them simultaneously, in particular when we use a single observational data. However, we show that we can obtain relatively severe constraints when we use all data sets from observations above even if we consider the time-varying equation of state and do not assume a flat universe. We also found that the combined data set favors a flat universe even if we consider the time variation of dark energy equation of state.Comment: 17 pages, 12 figures, references adde

    The Dwarf Nova Outbursts of Nova Her 1960 (=V446 Her)

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    V446 Her is the best example of an old nova which has developed dwarf nova eruptions in the post-nova state. We report on observed properties of the long-term light curve of V446 Her, using photometry over 19 years. Yearly averages of the outburst magnitudes shows a decline of ~0.013 mag/yr, consistent with the decline of other post-novae that do not have dwarf nova outbursts. Previous suggestions of bimodal distributions of the amplitudes and widths of the outbursts are confirmed. The outbursts occur at a mean spacing of 18 days but the range of spacings is large (13-30 days). From simulations of dwarf nova outbursts it has been predicted that the outburst spacing in V446 Her will increase as M-dot from the red dwarf companion slowly falls following the nova; however the large intrinsic scatter in the spacings serves to hide any evidence of this effect. We do find a systematic change in the outburst pattern in which the brighter, wider type of outbursts disappeared after late 2003, and this phenomenon is suggested to be due to falling M-dot following the nova.Comment: To appear at the Astronomical Journal; 7 pages, 1 table, 11 figure

    Changes in contractile proteins during differentiation of myeloid leukemia cells. II. Purification and characterization of actin

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    A myeloid leukemia cell line, M1, differentiates to macrophage and gains locomotive and phagocytic activity when incubated with conditioned medium (CM) from a fibroblast culture and bacterial endotoxin. To characterize the actin molecules before and after differentiation, the actin was purified through three sequential steps: DEAE-sephadex A- 50, polymerization/depolymerization, and sephadex G-150 chromatography. There were no essential differences between the inhibitory activity of actins from control M1 cells and CM-treated M1 cells on both DNase I and heavy meromyosin (HMMM) K(+)-EDTA-ATPase; the same dose response as with skeletal muscle actin took place. After the treatment with CM, however, the specific activity for the activation of HMMM Mg(2+)- ATPase by actin became two-fold that of untreated M1 actin, which was one third of the value for skeletal muscle actin. The V(max) for the control and the CM-treated M1 cell, as well as the skeletal muscle actins, proved to be the same. By contrast, the K(app) values for the control and CM-treated M1-cell actins were 3- and 1.5-fold the value for skeletal-muscle actin. This means that CM treatment of the M1 actin produced a twofold affinity for the Mg(2+)-ATPase of skeletal-muscle myosin. The critical concentrations for polymerization were compared under different salt concentrations and temperatures. Although no marked difference was found for the presence of 2 mM MgCl(2), 0.1 M KCl in place of MgCl(2) at 5 degrees C gave the following values: 0.1 mg/ml for skeletal-muscle actin, 0.7 mg/ml for control M1 actin, 0,5 mg/ml for CM- treated M1 actin, and 1.0 mg/ml for the D(-) subline that is insensitive to CM. Although the critical concentration of D(-) actin is extraordinarily high, this actin showed normal polymerization above the critical concentration. This together with the data presented in our previous paper, that the D(-) actin in the crude extract did not polymerize, suggests that an inhibitor for actin polymerization is present in the subline. The kinetics experiment at 0.1 M KCl and 25 degrees C revealed a slower polymerization of untreated M1- and D(-)-cell actins as compared with CM-treated M1 actin. This delayed polymerization was due to a delay during the nucleation stage, not during the elongation stage. By isoelectric focusing, the ratios of β- to γ-actin showed a marked difference depending on the states of cells: about 4.9 for control M1, 2.8 for CM-treated M1, and 7.6 for D(-)-subline actins. Tryptic peptide maps also revealed the presence of different peptides. Thus, the functional differences of actin before and after the differentiation was accompanied by some chemical changes in actin molecules

    Distance Measurement of Galaxies to Redshift of 0.1 using the CO-Line Tully-Fisher Relation

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    We report on the first results of a long-term project to derive distances of galaxies at cosmological distances by applying the CO-line width-luminosity relation. We have obtained deep CO-line observations of galaxies at redshifts up to 29,000 km/s using the Nobeyama 45-m mm-wave Telescope, and some supplementary data were obtained by using the IRAM 30-m telescope. We have detected the CO line emission for several galaxies, and used their CO line widths to estimate the absolute luminosities using the line-width-luminosity relation. In order to obtain photometric data and inclination correction, we also performed optical imaging observations of the CO-detected galaxies using the CFHT 3.6-m telescope at high resolution. The radio and optical data have been combined to derive the distance moduli and distances of the galaxies, and Hubble ratios were estimated for these galaxies. We propose that the CO line width-luminosity relation can be a powerful method to derive distances of galaxies to redfhift of z = 0.1 and to derive the Hubble ratio in a significant volume of the universe. Key words: Cosmology - Galaxies: general - Distance scale - CO lineComment: To appear in PASJ, Plain Tex, 3 figures (in 10 ps files

    Challenge of monitoring cohesive movement in homing fish using fine-scale 3D positioning

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    Rockfish, which are well known for their site fidelity and homing ability, live sympatrically with many conspecifics. Conspecifics may be external drivers influencing rockfish movement, and rockfish may move cohesively while travelling. We tested whether rockfish formed a group when returning to their original habitat after artificial displacement and examined the routes they travelled to return home. A fine-scale multi-individual simultaneous positioning method was used to observe the movement trajectories of tagged fish. Our results showed that tagged fish, released in groups, returned to their original habitat (5 of 8 fish) but generally did not travel with other individuals. There was one exception in which 2 individuals moved together for ~100 s immediately after release. These 2 fish had no designated leader, alternating as leader and follower. Our hypothesis was partially corroborated by these rockfish possibly travelling cohesively. The returning fish tended to travel along the sea bottom and the coastline, independent of current; thus, they likely used visual cues, rather than olfactory or social cues, to return home

    The Cosmic Neutrino Background and the Age of the Universe

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    We discuss the cosmological degeneracy between the age of the Universe, the Hubble parameter and the effective number of relativistic particles N_eff. We show that independent determinations of the Hubble parameter H(z) as those recently provided by Simon,Verde, Jimenez (2006), combined with other cosmological data sets can provide the most stringent constraint on N_eff, yielding N_eff=3.7 (-1.2) (+1.1) at 95% confidence level. A neutrino background is detected with high significance: N_eff >1.8 at better than 99% confidence level. Constraints on the age of the universe in the framework of an extra background of relativistic particles are improved by a factor 3.Comment: JCAP, in pres

    Live imaging of whole mouse embryos during gastrulation : migration analyses of epiblast and mesodermal cells

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    During gastrulation in the mouse embryo, dynamic cell movements including epiblast invagination and mesodermal layer expansion lead to the establishment of the three-layered body plan. The precise details of these movements, however, are sometimes elusive, because of the limitations in live imaging. To overcome this problem, we developed techniques to enable observation of living mouse embryos with digital scanned light sheet microscope (DSLM). The achieved deep and high time-resolution images of GFP-expressing nuclei and following 3D tracking analysis revealed the following findings: (i) Interkinetic nuclear migration (INM) occurs in the epiblast at embryonic day (E)6 and 6.5. (ii) INM-like migration occurs in the E5.5 embryo, when the epiblast is a monolayer and not yet pseudostratified. (iii) Primary driving force for INM at E6.5 is not pressure from neighboring nuclei. (iv) Mesodermal cells migrate not as a sheet but as individual cells without coordination

    Neutrino mass constraint from CMB and its degeneracy with other cosmological parameters

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    We show that the cosmic microwave background (CMB) data of WMAP can give subelectronvolt limit on the neutrino mass: m_nu < 0.63 eV (95% CL). We also investigate its degeneracy with other cosmological parameters. In particular, we show the Hubble constant derived from the WMAP data decreases considerably when the neutrino mass is a few times 0.1 eV.Comment: 3 pages, 2 figures, prepared for the TAUP2007 Proceeding

    An Unusual Combination of Neurological Manifestations and Sudden Vision Loss in a Child with Familial Hyperphosphatemic Tumoral Calcinosis

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    Hyperphosphatemia in the absence of renal failure is an unusual occurrence, particularly in children, but is a common primary feature of familial hyperphosphatemic tumor calcinosis. We report a child with hyperphosphatemia who presented with multiple episodes of neurologic dysfunction involving lower motor neuron facial nerve palsy along with sequential visual loss. He also had an episode of stroke. There was an extensive metastatic calcification of soft tissue and vasculature. Hyperphosphatemia with normal serum alkaline phosphatase, calcium, parathyroid hormone, and renal function was noted. He was managed with hemodialysis and sevelamer (3 months) without much success in reducing serum phosphate level, requiring continuous ambulatory peritoneal dialysis (3 years). Intact fibroblast growth factor 23 (FGF23) was undetectable, with C-terminal FGF23 fragments significantly elevated (2575 RU/ml, normal A (p.N162K) mutation in FGF23 exon 3, confirming the diagnoses of primary FGF23 deficiency, the first case to be reported from India
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